| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Omeprazole (sodium) perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Omeprazole (sodium)_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGF2 | insulin-like growth factor 2 | 0.218252 |
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | 0.0774497 |
| MAP1B | microtubule-associated protein 1B | 0.0620859 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | 0.0568883 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0488492 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.045577 |
| CD36 | CD36 molecule (thrombospondin receptor) | 0.0439136 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0435104 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0420996 |
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase | 0.0403411 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0375787 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0366939 |
| TPST1 | tyrosylprotein sulfotransferase 1 | 0.0365008 |
| ARHGAP9 | Rho GTPase activating protein 9 | 0.0343196 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | 0.0318874 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0294625 |
| AOPEP | aminopeptidase O (putative) | 0.0294266 |
| HAND2 | heart and neural crest derivatives expressed 2 | 0.027238 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.0271518 |
| MEIS2 | Meis homeobox 2 | 0.0268789 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0262968 |
| PTEN | phosphatase and tensin homolog | 0.0257041 |
| RNF145 | ring finger protein 145 | 0.0253471 |
| NEK7 | NIMA-related kinase 7 | 0.0249452 |
| FOXO3 | forkhead box O3 | 0.0245774 |
| RTN4 | reticulon 4 | 0.0240568 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0238509 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | 0.0234719 |
| GNA13 | guanine nucleotide binding protein (G protein), alpha 13 | 0.023464 |
| SSH1 | slingshot protein phosphatase 1 | 0.0233293 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0226188 |
| DST | dystonin | 0.0222957 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0218211 |
| MEIS1 | Meis homeobox 1 | 0.0217546 |
| KCTD3 | potassium channel tetramerization domain containing 3 | 0.0214742 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0212418 |
| USPL1 | ubiquitin specific peptidase like 1 | 0.0209982 |
| HAS2 | hyaluronan synthase 2 | 0.0209574 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0209543 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0209481 |
| APP | amyloid beta (A4) precursor protein | 0.0204644 |
| ARRDC3 | arrestin domain containing 3 | 0.0201129 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0201045 |
| SET | SET nuclear proto-oncogene | 0.0198123 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.0193982 |
| XPO1 | exportin 1 | 0.019018 |
| USP3 | ubiquitin specific peptidase 3 | 0.0188971 |
| EYA1 | EYA transcriptional coactivator and phosphatase 1 | 0.0186967 |
| GNG2 | guanine nucleotide binding protein (G protein), gamma 2 | 0.0185794 |
| WDR45B | WD repeat domain 45B | 0.0185236 |
| UHMK1 | U2AF homology motif (UHM) kinase 1 | 0.018459 |
| LONRF2 | LON peptidase N-terminal domain and ring finger 2 | 0.0183186 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0181256 |
| TMF1 | TATA element modulatory factor 1 | 0.01805 |
| SRPK2 | SRSF protein kinase 2 | 0.0180281 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0177129 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | 0.0175681 |
| MYO6 | myosin VI | 0.0172845 |
| RAB30 | RAB30, member RAS oncogene family | 0.0172763 |
| ABCA5 | ATP-binding cassette, sub-family A (ABC1), member 5 | 0.0168382 |
| CORO1C | coronin, actin binding protein, 1C | 0.0168238 |
| ITGA1 | integrin, alpha 1 | 0.0167911 |
| FCHSD2 | FCH and double SH3 domains 2 | 0.0167556 |
| ANGPT1 | angiopoietin 1 | 0.0167054 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | 0.0166695 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0164933 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0164673 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0163616 |
| USP12 | ubiquitin specific peptidase 12 | 0.0162865 |
| PRPF8 | pre-mRNA processing factor 8 | 0.0162347 |
| ARL8B | ADP-ribosylation factor-like 8B | 0.0161748 |
| CLCN3 | chloride channel, voltage-sensitive 3 | 0.0160531 |
| CASC3 | cancer susceptibility candidate 3 | 0.015871 |
| NAA50 | N(alpha)-acetyltransferase 50, NatE catalytic subunit | 0.0158128 |
| SLC41A2 | solute carrier family 41 (magnesium transporter), member 2 | 0.0157391 |
| CDON | cell adhesion associated, oncogene regulated | 0.0156795 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0156629 |
| RUNX1T1 | runt-related transcription factor 1; translocated to, 1 (cyclin D-related) | 0.015604 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | 0.015587 |
| FKBP10 | FK506 binding protein 10, 65 kDa | 0.0154918 |
| ATP6V0A1 | ATPase, H+ transporting, lysosomal V0 subunit a1 | 0.0154503 |
| FDFT1 | farnesyl-diphosphate farnesyltransferase 1 | 0.0153593 |
| SLITRK6 | SLIT and NTRK-like family, member 6 | 0.0152758 |
| CDC73 | cell division cycle 73 | 0.0152734 |
| CHRM3 | cholinergic receptor, muscarinic 3 | 0.0151427 |
| L1CAM | L1 cell adhesion molecule | 0.0151147 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0150595 |
| ZNF148 | zinc finger protein 148 | 0.0150082 |
| VEGFA | vascular endothelial growth factor A | 0.0149753 |
| NCKAP1 | NCK-associated protein 1 | 0.0149526 |
| FNBP1 | formin binding protein 1 | 0.0149372 |
| EFTUD2 | elongation factor Tu GTP binding domain containing 2 | 0.0147559 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0146694 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0146643 |
| BDKRB2 | bradykinin receptor B2 | 0.0146056 |
| ZBTB1 | zinc finger and BTB domain containing 1 | 0.014597 |
| TANC1 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 | 0.0145002 |
| MSMO1 | methylsterol monooxygenase 1 | 0.0144844 |
| CAB39 | calcium binding protein 39 | 0.0144602 |
| PCTP | phosphatidylcholine transfer protein | 0.0144271 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LSAMP | limbic system-associated membrane protein | -0.222782 |
| NRG1 | neuregulin 1 | -0.201005 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.184778 |
| VCL | vinculin | -0.162495 |
| PRKCA | protein kinase C, alpha | -0.14386 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.12163 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.102744 |
| EXT1 | exostosin glycosyltransferase 1 | -0.100615 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.099577 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0840077 |
| LRFN5 | leucine rich repeat and fibronectin type III domain containing 5 | -0.0833098 |
| CUX1 | cut-like homeobox 1 | -0.0772543 |
| ACTG1 | actin gamma 1 | -0.0766209 |
| MCL1 | myeloid cell leukemia 1 | -0.06999 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | -0.0698137 |
| TRIB2 | tribbles pseudokinase 2 | -0.0695791 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0669491 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.0668477 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.065776 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0651764 |
| RPL23 | ribosomal protein L23 | -0.0641163 |
| ZNF804A | zinc finger protein 804A | -0.0614566 |
| RPS6 | ribosomal protein S6 | -0.0609235 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0608012 |
| MSI2 | musashi RNA-binding protein 2 | -0.0590298 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0568202 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0562744 |
| MED13 | mediator complex subunit 13 | -0.0538512 |
| UNC5C | unc-5 homolog C (C. elegans) | -0.0535213 |
| SMYD3 | SET and MYND domain containing 3 | -0.0525004 |
| CADM2 | cell adhesion molecule 2 | -0.0507204 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0499305 |
| SYT1 | synaptotagmin I | -0.0490754 |
| ST6GALNAC3 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 | -0.0479907 |
| MAPK10 | mitogen-activated protein kinase 10 | -0.0474957 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.0474514 |
| GSE1 | Gse1 coiled-coil protein | -0.0461792 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0459852 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0459184 |
| ANTXR1 | anthrax toxin receptor 1 | -0.0449313 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.0444693 |
| SP100 | SP100 nuclear antigen | -0.0442013 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0438784 |
| COL1A1 | collagen, type I, alpha 1 | -0.0433884 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0427883 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0421013 |
| EFNA5 | ephrin-A5 | -0.042089 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0417713 |
| TLE4 | transducin-like enhancer of split 4 | -0.0409007 |
| TPM1 | tropomyosin 1 (alpha) | -0.0408729 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0402872 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.039886 |
| MBTD1 | mbt domain containing 1 | -0.0390939 |
| PDZRN3 | PDZ domain containing ring finger 3 | -0.0386361 |
| AFF3 | AF4/FMR2 family, member 3 | -0.0385593 |
| MYO1E | myosin IE | -0.0381992 |
| PTMA | prothymosin, alpha | -0.0380437 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0379705 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0377413 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0374297 |
| IER3 | immediate early response 3 | -0.0370009 |
| RPL19 | ribosomal protein L19 | -0.0369373 |
| RAD51B | RAD51 paralog B | -0.0369359 |
| BPTF | bromodomain PHD finger transcription factor | -0.0366766 |
| RPTOR | regulatory associated protein of MTOR, complex 1 | -0.0366563 |
| PARD3 | par-3 family cell polarity regulator | -0.0360041 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0359812 |
| PBX1 | pre-B-cell leukemia homeobox 1 | -0.0359074 |
| INTS6 | integrator complex subunit 6 | -0.0355832 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0351638 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0349119 |
| RPS19 | ribosomal protein S19 | -0.0345979 |
| CDH13 | cadherin 13 | -0.0343192 |
| EGR1 | early growth response 1 | -0.0342179 |
| GREM2 | gremlin 2, DAN family BMP antagonist | -0.0341911 |
| DIAPH2 | diaphanous-related formin 2 | -0.0337815 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0335309 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0331653 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0329194 |
| TMSB10 | thymosin beta 10 | -0.0328701 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0327433 |
| TPM4 | tropomyosin 4 | -0.0326391 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0325234 |
| VIM | vimentin | -0.032495 |
| AUTS2 | autism susceptibility candidate 2 | -0.032345 |
| DACH2 | dachshund family transcription factor 2 | -0.03198 |
| CADM1 | cell adhesion molecule 1 | -0.0319353 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0316935 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0316817 |
| PPM1D | protein phosphatase, Mg2+/Mn2+ dependent, 1D | -0.0315476 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0310529 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0309277 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0308341 |
| TCF12 | transcription factor 12 | -0.0307268 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0306709 |
| CANX | calnexin | -0.0306203 |
| EGFR | epidermal growth factor receptor | -0.0305314 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0305272 |
| NREP | neuronal regeneration related protein | -0.030515 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0305007 |
