| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Omeprazole (sodium) perturbation in H4 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Omeprazole (sodium)_H4 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL6A3 | collagen, type VI, alpha 3 | 0.141709 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0902967 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.078346 |
| EGFR | epidermal growth factor receptor | 0.0744811 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0739143 |
| SMAD3 | SMAD family member 3 | 0.0633479 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0591062 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0583433 |
| DST | dystonin | 0.0556048 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0529284 |
| STC1 | stanniocalcin 1 | 0.0524462 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0479283 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0476845 |
| ATP13A3 | ATPase type 13A3 | 0.0476732 |
| INHBA | inhibin, beta A | 0.0473686 |
| LOX | lysyl oxidase | 0.0468739 |
| NDRG1 | N-myc downstream regulated 1 | 0.0453156 |
| SBF2 | SET binding factor 2 | 0.0452333 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0419973 |
| ANO6 | anoctamin 6 | 0.0393932 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0389581 |
| RTN4 | reticulon 4 | 0.0389351 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0384041 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0381159 |
| OSMR | oncostatin M receptor | 0.0377931 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0370219 |
| MSN | moesin | 0.0363277 |
| TNNC1 | troponin C type 1 (slow) | 0.0342247 |
| COPB1 | coatomer protein complex, subunit beta 1 | 0.0341683 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0340561 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0340555 |
| HDAC9 | histone deacetylase 9 | 0.0331479 |
| CADM1 | cell adhesion molecule 1 | 0.0330709 |
| SNX13 | sorting nexin 13 | 0.0308009 |
| USP47 | ubiquitin specific peptidase 47 | 0.0307871 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0305859 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0304347 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0302747 |
| TMEM39A | transmembrane protein 39A | 0.0299726 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0299298 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0298655 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.029858 |
| CLTC | clathrin, heavy chain (Hc) | 0.0296007 |
| YEATS2 | YEATS domain containing 2 | 0.02914 |
| FNIP1 | folliculin interacting protein 1 | 0.028809 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0287631 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0286224 |
| GOLGB1 | golgin B1 | 0.0285568 |
| MYOF | myoferlin | 0.0285232 |
| COPA | coatomer protein complex, subunit alpha | 0.0284808 |
| HELZ | helicase with zinc finger | 0.0284793 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.028231 |
| CANX | calnexin | 0.0281031 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0279021 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0276472 |
| TXNIP | thioredoxin interacting protein | 0.0275898 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0274027 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0271239 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0269073 |
| OGA | O-GlcNAcase | 0.0268495 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.026814 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0267066 |
| COG5 | component of oligomeric golgi complex 5 | 0.0263126 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0262533 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0261578 |
| VMP1 | vacuole membrane protein 1 | 0.0257824 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0256817 |
| LRRC49 | leucine rich repeat containing 49 | 0.0254639 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0250606 |
| MAP1B | microtubule-associated protein 1B | 0.0246639 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0246122 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0246086 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0245807 |
| SETD5 | SET domain containing 5 | 0.0244707 |
| WDR26 | WD repeat domain 26 | 0.0241441 |
| RARS1 | arginyl-tRNA synthetase 1 | 0.0241276 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0241205 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0240657 |
| RASA2 | RAS p21 protein activator 2 | 0.0236424 |
| UTY | ubiquitously transcribed tetratricopeptide repeat containing, Y-linked | 0.02341 |
| LMAN1 | lectin, mannose-binding, 1 | 0.0232983 |
| MON2 | MON2 homolog (S. cerevisiae) | 0.0231474 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0225943 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | 0.0225915 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0224513 |
| CCDC14 | coiled-coil domain containing 14 | 0.0222673 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0219609 |
| FAM13A | family with sequence similarity 13, member A | 0.0218843 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | 0.021848 |
| TNS3 | tensin 3 | 0.0215206 |
| PMM2 | phosphomannomutase 2 | 0.0213947 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0213457 |
| PRKCSH | protein kinase C substrate 80K-H | 0.021221 |
| GOLGA4 | golgin A4 | 0.0212079 |
| ZNF841 | zinc finger protein 841 | 0.0210584 |
| FAM114A1 | family with sequence similarity 114, member A1 | 0.0205348 |
| ERBIN | erbb2 interacting protein | 0.0205283 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0204709 |
| PRELID2 | PRELI domain containing 2 | 0.0204338 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0203216 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.163091 |
| VIM | vimentin | -0.147722 |
| PTMA | prothymosin, alpha | -0.11754 |
| MT2A | metallothionein 2A | -0.108153 |
| HLA-B | major histocompatibility complex, class I, B | -0.107227 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0997471 |
| B2M | beta-2-microglobulin | -0.0990104 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0930648 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0907819 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0824824 |
| RPL35A | ribosomal protein L35a | -0.0809371 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0763178 |
| FN1 | fibronectin 1 | -0.0716094 |
| RPS8 | ribosomal protein S8 | -0.0647935 |
| RPS6 | ribosomal protein S6 | -0.0627054 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0625461 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0618728 |
| RPL37A | ribosomal protein L37a | -0.0582058 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0578181 |
| HLA-A | major histocompatibility complex, class I, A | -0.0576436 |
| RPS13 | ribosomal protein S13 | -0.0568724 |
| FTL | ferritin, light polypeptide | -0.0563386 |
| RPLP1 | ribosomal protein, large, P1 | -0.050524 |
| NLGN1 | neuroligin 1 | -0.0497083 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0494082 |
| RPL23 | ribosomal protein L23 | -0.0487 |
| RPL31 | ribosomal protein L31 | -0.0455119 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0455075 |
| RPLP2 | ribosomal protein, large, P2 | -0.0447711 |
| RPS25 | ribosomal protein S25 | -0.0425883 |
| RPL34 | ribosomal protein L34 | -0.0422994 |
| RPL9 | ribosomal protein L9 | -0.0419297 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0411333 |
| RPL28 | ribosomal protein L28 | -0.040254 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0402185 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0397009 |
| RPS24 | ribosomal protein S24 | -0.0362382 |
| IGF2 | insulin-like growth factor 2 | -0.0345498 |
| ACTG1 | actin gamma 1 | -0.0341716 |
| ENO1 | enolase 1, (alpha) | -0.0341121 |
| RPS23 | ribosomal protein S23 | -0.0335025 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0329941 |
| SEC61G | Sec61 gamma subunit | -0.0322777 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0315811 |
| TPM4 | tropomyosin 4 | -0.0314663 |
| RPS16 | ribosomal protein S16 | -0.0309677 |
| RPS27A | ribosomal protein S27a | -0.0308863 |
| RPL11 | ribosomal protein L11 | -0.030165 |
| PRSS23 | protease, serine, 23 | -0.0294242 |
| RPS29 | ribosomal protein S29 | -0.0294042 |
| RPS11 | ribosomal protein S11 | -0.0291849 |
| RPL7A | ribosomal protein L7a | -0.0289245 |
| RPS12 | ribosomal protein S12 | -0.028466 |
| RPL38 | ribosomal protein L38 | -0.027145 |
| RPL37 | ribosomal protein L37 | -0.0268165 |
| S100A10 | S100 calcium binding protein A10 | -0.0266941 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.0266156 |
| RPS21 | ribosomal protein S21 | -0.0264943 |
| HLA-C | major histocompatibility complex, class I, C | -0.0262453 |
| RPS3 | ribosomal protein S3 | -0.0260874 |
| FAM162A | family with sequence similarity 162, member A | -0.0260311 |
| S100A6 | S100 calcium binding protein A6 | -0.0259224 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0258412 |
| RPS17 | ribosomal protein S17 | -0.0258137 |
| S100A9 | S100 calcium binding protein A9 | -0.0257418 |
| RPS19 | ribosomal protein S19 | -0.0256487 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0255529 |
| RPS14 | ribosomal protein S14 | -0.025329 |
| RPL27A | ribosomal protein L27a | -0.0249458 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0248264 |
| RPL12 | ribosomal protein L12 | -0.0248039 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0245299 |
| RPL36 | ribosomal protein L36 | -0.0245214 |
| RACK1 | receptor for activated C kinase 1 | -0.0241978 |
| SQSTM1 | sequestosome 1 | -0.02411 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0236955 |
| GNAS | GNAS complex locus | -0.0236457 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | -0.0230306 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.022972 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0224105 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0223931 |
| RPS5 | ribosomal protein S5 | -0.0223841 |
| FBXO11 | F-box protein 11 | -0.0219808 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0219466 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0218765 |
| TOMM7 | translocase of outer mitochondrial membrane 7 homolog (yeast) | -0.0217595 |
| DTNA | dystrobrevin, alpha | -0.0216842 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0213 |
| POTEF | POTE ankyrin domain family, member F | -0.021018 |
| DGKI | diacylglycerol kinase, iota | -0.0209065 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0204239 |
| RPS10 | ribosomal protein S10 | -0.0201075 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | -0.0200318 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0198973 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0198853 |
| ZNF804A | zinc finger protein 804A | -0.0198068 |
| ATF4 | activating transcription factor 4 | -0.0197808 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0196586 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0196216 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0195733 |