| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Omeprazole (sodium) perturbation in HCT15 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Omeprazole (sodium)_HCT15 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.177411 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.122554 |
| NDRG1 | N-myc downstream regulated 1 | 0.0591442 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0577933 |
| FNIP1 | folliculin interacting protein 1 | 0.0515963 |
| TMF1 | TATA element modulatory factor 1 | 0.051201 |
| ARF4 | ADP-ribosylation factor 4 | 0.0509704 |
| PGK1 | phosphoglycerate kinase 1 | 0.0500887 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0455201 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0443933 |
| GOLGA4 | golgin A4 | 0.0435262 |
| YEATS2 | YEATS domain containing 2 | 0.0378663 |
| FOXO3 | forkhead box O3 | 0.0378548 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0370667 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0370026 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0368296 |
| DSPP | dentin sialophosphoprotein | 0.0365624 |
| VMP1 | vacuole membrane protein 1 | 0.0365601 |
| NUP58 | nucleoporin 58 | 0.0360363 |
| ZNF638 | zinc finger protein 638 | 0.0354419 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0350168 |
| HELZ | helicase with zinc finger | 0.0349522 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0341447 |
| FAM117B | family with sequence similarity 117, member B | 0.0336874 |
| SEC24A | SEC24 family member A | 0.0336693 |
| EZR | ezrin | 0.0335505 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0334347 |
| VEGFA | vascular endothelial growth factor A | 0.0333944 |
| MKI67 | marker of proliferation Ki-67 | 0.033268 |
| ARRDC3 | arrestin domain containing 3 | 0.0317875 |
| CDCP1 | CUB domain containing protein 1 | 0.0313877 |
| COG6 | component of oligomeric golgi complex 6 | 0.0307158 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0287271 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0285816 |
| EGR1 | early growth response 1 | 0.0285091 |
| RUNX1 | runt-related transcription factor 1 | 0.0284292 |
| KDM7A | lysine (K)-specific demethylase 7A | 0.0273835 |
| PRPF8 | pre-mRNA processing factor 8 | 0.0273671 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0273255 |
| PCM1 | pericentriolar material 1 | 0.0272241 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0272148 |
| CDK19 | cyclin-dependent kinase 19 | 0.0269579 |
| COPA | coatomer protein complex, subunit alpha | 0.0262815 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | 0.0261596 |
| SETD5 | SET domain containing 5 | 0.0255203 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0248746 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0246744 |
| DCAF7 | DDB1 and CUL4 associated factor 7 | 0.0246187 |
| RHOA | ras homolog family member A | 0.0243211 |
| MAP3K13 | mitogen-activated protein kinase kinase kinase 13 | 0.0237958 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0237094 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0230668 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0227237 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.022616 |
| HERC3 | HECT and RLD domain containing E3 ubiquitin protein ligase 3 | 0.0225974 |
| RCOR1 | REST corepressor 1 | 0.022415 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0223285 |
| TSR1 | TSR1, 20S rRNA accumulation, homolog (S. cerevisiae) | 0.0223023 |
| PDXDC1 | pyridoxal-dependent decarboxylase domain containing 1 | 0.0221912 |
| LMO7 | LIM domain 7 | 0.0219785 |
| EP300 | E1A binding protein p300 | 0.0218577 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0216636 |
| EPHA2 | EPH receptor A2 | 0.0214578 |
| RPL3 | ribosomal protein L3 | 0.0213089 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0208533 |
| CCNL1 | cyclin L1 | 0.0207682 |
| TLN1 | talin 1 | 0.0207041 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.0205169 |
| ARL5B | ADP-ribosylation factor-like 5B | 0.0204993 |
| COPB1 | coatomer protein complex, subunit beta 1 | 0.0204533 |
| TXNIP | thioredoxin interacting protein | 0.0203964 |
| SPAG9 | sperm associated antigen 9 | 0.0201185 |
| RNMT | RNA (guanine-7-) methyltransferase | 0.0201084 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0200322 |
| HJURP | Holliday junction recognition protein | 0.0199206 |
| MCL1 | myeloid cell leukemia 1 | 0.0197236 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0197028 |
| YTHDC1 | YTH domain containing 1 | 0.0196555 |
| SRP54 | signal recognition particle 54kDa | 0.0195926 |
| USP8 | ubiquitin specific peptidase 8 | 0.019553 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0195356 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0194231 |
| AP3S1 | adaptor-related protein complex 3, sigma 1 subunit | 0.0192899 |
| GPR107 | G protein-coupled receptor 107 | 0.019289 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0192757 |
| SNX9 | sorting nexin 9 | 0.0191566 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0190622 |
| DDX6 | DEAD (Asp-Glu-Ala-Asp) box helicase 6 | 0.0190306 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0189997 |
| FAM193A | family with sequence similarity 193, member A | 0.018886 |
| SEC16A | SEC16 homolog A (S. cerevisiae) | 0.0187049 |
| SLK | STE20-like kinase | 0.0183727 |
| SCFD1 | sec1 family domain containing 1 | 0.0183545 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.018206 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0181581 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0180697 |
| GOLGA2 | golgin A2 | 0.0180561 |
| TMEM87A | transmembrane protein 87A | 0.0180561 |
| TMEM41B | transmembrane protein 41B | 0.0179461 |
| TENT2 | terminal nucleotidyltransferase 2 | 0.0178675 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.195265 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.167225 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.145199 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.1259 |
| AHNAK | AHNAK nucleoprotein | -0.123197 |
| FAT1 | FAT atypical cadherin 1 | -0.104786 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.102753 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.101155 |
| PTMA | prothymosin, alpha | -0.0921503 |
| RPS8 | ribosomal protein S8 | -0.0814986 |
| MED13L | mediator complex subunit 13-like | -0.074256 |
| TMSB10 | thymosin beta 10 | -0.0734845 |
| FHIT | fragile histidine triad | -0.0723959 |
| RPS6 | ribosomal protein S6 | -0.0704532 |
| RPS24 | ribosomal protein S24 | -0.0679714 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0678383 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0676098 |
| WWOX | WW domain containing oxidoreductase | -0.0637873 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0620592 |
| RRBP1 | ribosome binding protein 1 | -0.0616026 |
| RPL26 | ribosomal protein L26 | -0.0591316 |
| RPLP1 | ribosomal protein, large, P1 | -0.0586617 |
| RAD51B | RAD51 paralog B | -0.0576957 |
| RPL35A | ribosomal protein L35a | -0.0562746 |
| CANX | calnexin | -0.0557866 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0536873 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0514421 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.05041 |
| RPL23 | ribosomal protein L23 | -0.0504086 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.0502445 |
| KRT8 | keratin 8, type II | -0.049057 |
| FUS | FUS RNA binding protein | -0.048565 |
| RPS21 | ribosomal protein S21 | -0.048347 |
| RPL37A | ribosomal protein L37a | -0.0459017 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0457927 |
| RPL34 | ribosomal protein L34 | -0.0457161 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0454824 |
| TENM3 | teneurin transmembrane protein 3 | -0.0448534 |
| RPL27A | ribosomal protein L27a | -0.0440975 |
| RPLP0 | ribosomal protein, large, P0 | -0.0436828 |
| TXNRD1 | thioredoxin reductase 1 | -0.0433785 |
| RPL12 | ribosomal protein L12 | -0.0433265 |
| RPL30 | ribosomal protein L30 | -0.0405956 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0405943 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0399607 |
| RPLP2 | ribosomal protein, large, P2 | -0.0395817 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0395283 |
| RPL11 | ribosomal protein L11 | -0.0392687 |
| HMGB1 | high mobility group box 1 | -0.037191 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0371249 |
| SPIDR | scaffolding protein involved in DNA repair | -0.0370437 |
| RPL5 | ribosomal protein L5 | -0.0367171 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0360557 |
| TBC1D4 | TBC1 domain family, member 4 | -0.0360409 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0348956 |
| ENO1 | enolase 1, (alpha) | -0.0348858 |
| RPL19 | ribosomal protein L19 | -0.0348749 |
| RBM39 | RNA binding motif protein 39 | -0.0345677 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0343668 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0340211 |
| EXOC4 | exocyst complex component 4 | -0.033673 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0336277 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0329656 |
| ANXA2 | annexin A2 | -0.0322406 |
| APP | amyloid beta (A4) precursor protein | -0.0322148 |
| RPL35 | ribosomal protein L35 | -0.0318633 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0316476 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0311949 |
| OLA1 | Obg-like ATPase 1 | -0.0310627 |
| RPS27A | ribosomal protein S27a | -0.0309021 |
| RPS12 | ribosomal protein S12 | -0.030703 |
| ZNRF3 | zinc and ring finger 3 | -0.0306 |
| RPL36 | ribosomal protein L36 | -0.0303047 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0300493 |
| RPS20 | ribosomal protein S20 | -0.030004 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0299617 |
| SRSF9 | serine/arginine-rich splicing factor 9 | -0.029956 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0295064 |
| PRDX1 | peroxiredoxin 1 | -0.0292226 |
| RPL31 | ribosomal protein L31 | -0.0290301 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0289437 |
| TCF12 | transcription factor 12 | -0.0289072 |
| RPL7 | ribosomal protein L7 | -0.0288577 |
| LDHB | lactate dehydrogenase B | -0.0288552 |
| HOXB3 | homeobox B3 | -0.0288481 |
| RPS19 | ribosomal protein S19 | -0.0288123 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0287587 |
| SMYD3 | SET and MYND domain containing 3 | -0.0287404 |
| KRT18 | keratin 18, type I | -0.028697 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.028457 |
| RPL9 | ribosomal protein L9 | -0.0283495 |
| S100A10 | S100 calcium binding protein A10 | -0.0281417 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | -0.0280649 |
| RPL27 | ribosomal protein L27 | -0.027835 |
| RPL13A | ribosomal protein L13a | -0.0276609 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0270586 |
| JMJD1C | jumonji domain containing 1C | -0.0268963 |
| CCT4 | chaperonin containing TCP1, subunit 4 (delta) | -0.0268412 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0268269 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0268165 |
