| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Omeprazole (sodium) perturbation in HEC-1-A cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Omeprazole (sodium)_HEC-1-A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| POTEF | POTE ankyrin domain family, member F | 0.0567026 |
| NDRG1 | N-myc downstream regulated 1 | 0.0516161 |
| PRELID2 | PRELI domain containing 2 | 0.0483569 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0345494 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.033996 |
| ACTG1 | actin gamma 1 | 0.0319922 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0318599 |
| CCNL1 | cyclin L1 | 0.0314396 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.031017 |
| SNX9 | sorting nexin 9 | 0.0291644 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0290136 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0288138 |
| RNF145 | ring finger protein 145 | 0.0280265 |
| MYEOV | myeloma overexpressed | 0.0279362 |
| FLNA | filamin A, alpha | 0.0275769 |
| NCKAP1 | NCK-associated protein 1 | 0.0268612 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0257304 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0233903 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0221029 |
| PCBP2 | poly(rC) binding protein 2 | 0.0219101 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0217961 |
| CLDN4 | claudin 4 | 0.0216013 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0207769 |
| AFDN | afadin, adherens junction formation factor | 0.0206907 |
| AXL | AXL receptor tyrosine kinase | 0.0202006 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0197868 |
| SLC35F5 | solute carrier family 35, member F5 | 0.0194184 |
| AGRN | agrin | 0.0193099 |
| ICAM1 | intercellular adhesion molecule 1 | 0.0189128 |
| KIF5C | kinesin family member 5C | 0.0186774 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0183521 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0182964 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0178347 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0177772 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0173506 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0173272 |
| VEGFA | vascular endothelial growth factor A | 0.0168929 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0166021 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0163787 |
| ZNF292 | zinc finger protein 292 | 0.0163489 |
| LAMA5 | laminin, alpha 5 | 0.0163447 |
| INSIG2 | insulin induced gene 2 | 0.0163113 |
| SEPTIN9 | septin 9 | 0.0163084 |
| UBE2E1 | ubiquitin-conjugating enzyme E2E 1 | 0.0157842 |
| CYB5R3 | cytochrome b5 reductase 3 | 0.0148671 |
| SRPK1 | SRSF protein kinase 1 | 0.0148053 |
| YLPM1 | YLP motif containing 1 | 0.0147681 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0145767 |
| DCAF7 | DDB1 and CUL4 associated factor 7 | 0.0143483 |
| YWHAH | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta | 0.0143188 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.014198 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0141779 |
| RASA2 | RAS p21 protein activator 2 | 0.0137289 |
| ZNF148 | zinc finger protein 148 | 0.0135572 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0134727 |
| RPL21 | ribosomal protein L21 | 0.0133776 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 | 0.0132204 |
| FOSL1 | FOS-like antigen 1 | 0.0129951 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0129142 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0127997 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0127698 |
| OPTN | optineurin | 0.0127123 |
| FUBP1 | far upstream element (FUSE) binding protein 1 | 0.0125956 |
| NOTCH2 | notch 2 | 0.0125217 |
| RPL3 | ribosomal protein L3 | 0.0123948 |
| WASL | Wiskott-Aldrich syndrome-like | 0.012388 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.0123407 |
| WASF2 | WAS protein family, member 2 | 0.0122762 |
| CORO1C | coronin, actin binding protein, 1C | 0.0122654 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0122007 |
| SMAD4 | SMAD family member 4 | 0.0121577 |
| PITPNB | phosphatidylinositol transfer protein, beta | 0.0121453 |
| CDCP1 | CUB domain containing protein 1 | 0.0121248 |
| EGR1 | early growth response 1 | 0.0120854 |
| CD46 | CD46 molecule, complement regulatory protein | 0.0120244 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0119936 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0119256 |
| MTCH1 | mitochondrial carrier 1 | 0.011864 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0118172 |
| PKM | pyruvate kinase, muscle | 0.0117925 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0117649 |
| RCOR1 | REST corepressor 1 | 0.0115541 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | 0.0113894 |
| PLXNB2 | plexin B2 | 0.0113486 |
| RELA | v-rel avian reticuloendotheliosis viral oncogene homolog A | 0.0113381 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0111957 |
| JUP | junction plakoglobin | 0.011058 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0110248 |
| RHOF | ras homolog family member F (in filopodia) | 0.010947 |
| CDC73 | cell division cycle 73 | 0.0109453 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0109333 |
| RTN4 | reticulon 4 | 0.0107778 |
| ATN1 | atrophin 1 | 0.010752 |
| SLK | STE20-like kinase | 0.0106992 |
| RPL5 | ribosomal protein L5 | 0.0106272 |
| MIER1 | mesoderm induction early response 1, transcriptional regulator | 0.0105794 |
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 | 0.0105089 |
| RNASEH2A | ribonuclease H2, subunit A | 0.010446 |
| SMAD5 | SMAD family member 5 | 0.0104264 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0104259 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.200398 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.126684 |
| AHNAK | AHNAK nucleoprotein | -0.108221 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.099596 |
| ASPH | aspartate beta-hydroxylase | -0.0677684 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0674573 |
| TMSB10 | thymosin beta 10 | -0.066499 |
| CANX | calnexin | -0.0591836 |
| LAMB3 | laminin, beta 3 | -0.055545 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0542331 |
| TMSB4X | thymosin beta 4, X-linked | -0.0541476 |
| ENO1 | enolase 1, (alpha) | -0.0473652 |
| SSH2 | slingshot protein phosphatase 2 | -0.0466551 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0459123 |
| RHEX | regulator of hemoglobinization and erythroid cell expansion | -0.0455685 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0429442 |
| ANXA2 | annexin A2 | -0.0429233 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0421773 |
| LAMA4 | laminin, alpha 4 | -0.041049 |
| CREB5 | cAMP responsive element binding protein 5 | -0.0384743 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0382616 |
| DSCAML1 | Down syndrome cell adhesion molecule like 1 | -0.03816 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.037906 |
| HDLBP | high density lipoprotein binding protein | -0.0377472 |
| SMYD3 | SET and MYND domain containing 3 | -0.0376381 |
| TXNRD1 | thioredoxin reductase 1 | -0.0376186 |
| SVIL | supervillin | -0.037487 |
| JMJD1C | jumonji domain containing 1C | -0.0368384 |
| MKI67 | marker of proliferation Ki-67 | -0.0367159 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0354793 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0345353 |
| EXOC4 | exocyst complex component 4 | -0.0343778 |
| RAD51B | RAD51 paralog B | -0.0339643 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0339462 |
| EZR | ezrin | -0.0338391 |
| SQSTM1 | sequestosome 1 | -0.0331558 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0331472 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0318866 |
| HMGA2 | high mobility group AT-hook 2 | -0.0318004 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0317851 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0316154 |
| COA1 | cytochrome c oxidase assembly factor 1 homolog (S. cerevisiae) | -0.0305489 |
| KAZN | kazrin, periplakin interacting protein | -0.0304715 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0304417 |
| ANXA1 | annexin A1 | -0.0297488 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0297443 |
| CCND1 | cyclin D1 | -0.0297224 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0296536 |
| LAMC2 | laminin, gamma 2 | -0.0293198 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0291656 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0285977 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0278511 |
| ANKLE2 | ankyrin repeat and LEM domain containing 2 | -0.0277862 |
| H1-0 | H1.0 linker histone | -0.0277112 |
| PTMA | prothymosin, alpha | -0.027657 |
| TCF12 | transcription factor 12 | -0.0271983 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.027145 |
| FTL | ferritin, light polypeptide | -0.0267686 |
| DOCK1 | dedicator of cytokinesis 1 | -0.0267303 |
| EHBP1 | EH domain binding protein 1 | -0.0266999 |
| MAP4 | microtubule-associated protein 4 | -0.0266903 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0266512 |
| FHIT | fragile histidine triad | -0.0263867 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0262067 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0261077 |
| TULP4 | tubby like protein 4 | -0.0260176 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0260174 |
| GOLGA4 | golgin A4 | -0.0258047 |
| ATG7 | autophagy related 7 | -0.0257432 |
| PCSK5 | proprotein convertase subtilisin/kexin type 5 | -0.0255578 |
| UTRN | utrophin | -0.0254642 |
| LMNA | lamin A/C | -0.0254219 |
| GOLGB1 | golgin B1 | -0.0253051 |
| NF1 | neurofibromin 1 | -0.0251955 |
| RPL19 | ribosomal protein L19 | -0.0251595 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0251042 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | -0.0250947 |
| ANLN | anillin, actin binding protein | -0.0250065 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | -0.0247522 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0244804 |
| GNL3 | guanine nucleotide binding protein-like 3 (nucleolar) | -0.0244314 |
| FIGN | fidgetin | -0.0244226 |
| ACACA | acetyl-CoA carboxylase alpha | -0.024184 |
| OSBPL10 | oxysterol binding protein-like 10 | -0.0240135 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0240098 |
| CHD9 | chromodomain helicase DNA binding protein 9 | -0.0239349 |
| GPR39 | G protein-coupled receptor 39 | -0.023893 |
| APP | amyloid beta (A4) precursor protein | -0.0238779 |
| RPL32 | ribosomal protein L32 | -0.02363 |
| CLTC | clathrin, heavy chain (Hc) | -0.0235888 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0235666 |
| BICC1 | BicC family RNA binding protein 1 | -0.0234805 |
| CLDN1 | claudin 1 | -0.023418 |
| G3BP1 | GTPase activating protein (SH3 domain) binding protein 1 | -0.023196 |
| NDUFAF2 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 2 | -0.0231882 |
| DOCK3 | dedicator of cytokinesis 3 | -0.0231416 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.023126 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.022799 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | -0.022795 |
| BBX | bobby sox homolog (Drosophila) | -0.0225779 |
