| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Omeprazole (sodium) perturbation in HOP62 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Omeprazole (sodium)_HOP62 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.192365 |
| FN1 | fibronectin 1 | 0.182422 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.137194 |
| COL6A1 | collagen, type VI, alpha 1 | 0.104615 |
| IGF2 | insulin-like growth factor 2 | 0.0825704 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0796399 |
| LOX | lysyl oxidase | 0.0770935 |
| COL6A2 | collagen, type VI, alpha 2 | 0.0748557 |
| VEGFA | vascular endothelial growth factor A | 0.0699291 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0688097 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0645546 |
| NDRG1 | N-myc downstream regulated 1 | 0.0637025 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0625034 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0606416 |
| DST | dystonin | 0.0605985 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0599043 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0568304 |
| COL5A1 | collagen, type V, alpha 1 | 0.056806 |
| SPAG9 | sperm associated antigen 9 | 0.0567138 |
| HMGA2 | high mobility group AT-hook 2 | 0.0547907 |
| MSN | moesin | 0.0541494 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0533463 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0515845 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0504455 |
| FAM13A | family with sequence similarity 13, member A | 0.0481865 |
| ADM | adrenomedullin | 0.0464295 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0459685 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0458879 |
| NUP58 | nucleoporin 58 | 0.0455273 |
| DTNA | dystrobrevin, alpha | 0.045455 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0445505 |
| ACTG1 | actin gamma 1 | 0.0439992 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0439499 |
| GOLGA4 | golgin A4 | 0.0438618 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0422774 |
| SETD5 | SET domain containing 5 | 0.0413642 |
| RNF145 | ring finger protein 145 | 0.0411906 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0410306 |
| L1CAM | L1 cell adhesion molecule | 0.0400856 |
| PGK1 | phosphoglycerate kinase 1 | 0.0398097 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.03938 |
| SFTPA2 | surfactant protein A2 | 0.038517 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0384717 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0378162 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0371337 |
| MYO10 | myosin X | 0.0370455 |
| FLNB | filamin B, beta | 0.0370415 |
| HPCAL1 | hippocalcin-like 1 | 0.0369656 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0366258 |
| HELZ | helicase with zinc finger | 0.0362102 |
| LOXL2 | lysyl oxidase-like 2 | 0.0354213 |
| ZNF292 | zinc finger protein 292 | 0.0353967 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0344588 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0342687 |
| ATP13A3 | ATPase type 13A3 | 0.0340704 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0340209 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0337338 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0334024 |
| TNS1 | tensin 1 | 0.0331974 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0331559 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0331227 |
| PTK2 | protein tyrosine kinase 2 | 0.0328741 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0327008 |
| RNF24 | ring finger protein 24 | 0.0326126 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.032426 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0323586 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0318488 |
| VMP1 | vacuole membrane protein 1 | 0.0317447 |
| ZNF148 | zinc finger protein 148 | 0.0308714 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0307674 |
| RAI14 | retinoic acid induced 14 | 0.0307059 |
| SEC24A | SEC24 family member A | 0.0306927 |
| COPA | coatomer protein complex, subunit alpha | 0.0305773 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.030544 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0302261 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0298197 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0298006 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0294998 |
| CAPRIN2 | caprin family member 2 | 0.0294723 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0294523 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0293856 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0293764 |
| TGFB1 | transforming growth factor, beta 1 | 0.0290955 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0289649 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0289074 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0288549 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0287639 |
| RPL3 | ribosomal protein L3 | 0.0285266 |
| TENM2 | teneurin transmembrane protein 2 | 0.0282025 |
| CDH13 | cadherin 13 | 0.0281837 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.02804 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0279966 |
| SRP54 | signal recognition particle 54kDa | 0.0274689 |
| FLNA | filamin A, alpha | 0.0274561 |
| CCNL1 | cyclin L1 | 0.0273824 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0269207 |
| SMAD3 | SMAD family member 3 | 0.0269178 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.026747 |
| MYO1B | myosin IB | 0.0267441 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0264758 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.240193 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.218978 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.155933 |
| MT2A | metallothionein 2A | -0.130178 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.120325 |
| TMSB10 | thymosin beta 10 | -0.105825 |
| PTMA | prothymosin, alpha | -0.0891407 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0885976 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0818375 |
| RPS24 | ribosomal protein S24 | -0.0618502 |
| AHNAK | AHNAK nucleoprotein | -0.0618362 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0616683 |
| IER3 | immediate early response 3 | -0.0615568 |
| RPL35A | ribosomal protein L35a | -0.0564498 |
| FTL | ferritin, light polypeptide | -0.0517014 |
| CANX | calnexin | -0.0506209 |
| RPLP1 | ribosomal protein, large, P1 | -0.0443473 |
| S100A10 | S100 calcium binding protein A10 | -0.0432888 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0393904 |
| RPL12 | ribosomal protein L12 | -0.0389034 |
| ENO1 | enolase 1, (alpha) | -0.0364793 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0350685 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0330411 |
| MT1X | metallothionein 1X | -0.0323759 |
| RPL34 | ribosomal protein L34 | -0.0317852 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0317733 |
| CD44 | CD44 molecule (Indian blood group) | -0.0312337 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0306821 |
| DUSP6 | dual specificity phosphatase 6 | -0.0304455 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0297632 |
| ANXA2 | annexin A2 | -0.0296399 |
| RPL23 | ribosomal protein L23 | -0.0290439 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0269864 |
| RPL19 | ribosomal protein L19 | -0.0263784 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0256124 |
| RPS19 | ribosomal protein S19 | -0.0255226 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0254554 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0252722 |
| RPS6 | ribosomal protein S6 | -0.0249754 |
| S100A6 | S100 calcium binding protein A6 | -0.0242337 |
| RPS8 | ribosomal protein S8 | -0.0240483 |
| H3-3B | H3.3 histone B | -0.0236243 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0235901 |
| MORF4L2 | mortality factor 4 like 2 | -0.0234738 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0233813 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0227169 |
| TXNIP | thioredoxin interacting protein | -0.0226791 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0220315 |
| MAP1B | microtubule-associated protein 1B | -0.0216939 |
| RPS21 | ribosomal protein S21 | -0.021312 |
| RPL9 | ribosomal protein L9 | -0.0212438 |
| LMNA | lamin A/C | -0.0211103 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0210696 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0207218 |
| RPLP0 | ribosomal protein, large, P0 | -0.0204982 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0194586 |
| RRM2 | ribonucleotide reductase M2 | -0.0192258 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.0190122 |
| HMGB1 | high mobility group box 1 | -0.0189092 |
| TUBB | tubulin, beta class I | -0.0188519 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0186515 |
| NRP1 | neuropilin 1 | -0.018202 |
| RPL32 | ribosomal protein L32 | -0.0180593 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0179748 |
| RPS16 | ribosomal protein S16 | -0.0176228 |
| HDLBP | high density lipoprotein binding protein | -0.0175995 |
| RPS23 | ribosomal protein S23 | -0.0174152 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0172403 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0171543 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0171219 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | -0.0170533 |
| EREG | epiregulin | -0.0168587 |
| RRBP1 | ribosome binding protein 1 | -0.0167358 |
| TMEM263 | transmembrane protein 263 | -0.0166738 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0164542 |
| CCNI | cyclin I | -0.01626 |
| TPI1 | triosephosphate isomerase 1 | -0.0162042 |
| GNAS | GNAS complex locus | -0.0161416 |
| H1-0 | H1.0 linker histone | -0.0161219 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0160893 |
| RPL31 | ribosomal protein L31 | -0.0160825 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.015697 |
| SYNJ2 | synaptojanin 2 | -0.0156768 |
| RPLP2 | ribosomal protein, large, P2 | -0.0156756 |
| GNS | glucosamine (N-acetyl)-6-sulfatase | -0.0149321 |
| RPL8 | ribosomal protein L8 | -0.0148532 |
| COL1A1 | collagen, type I, alpha 1 | -0.0148135 |
| UBB | ubiquitin B | -0.0148109 |
| RPL36A | ribosomal protein L36a | -0.014638 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0146015 |
| PRR11 | proline rich 11 | -0.0145843 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -0.0145231 |
| KLF6 | Kruppel-like factor 6 | -0.014461 |
| CDCP1 | CUB domain containing protein 1 | -0.0144456 |
| RPS27A | ribosomal protein S27a | -0.0142857 |
| PRMT2 | protein arginine methyltransferase 2 | -0.0142596 |
| CPNE3 | copine III | -0.0142085 |
| EXOC4 | exocyst complex component 4 | -0.0141045 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0138346 |
| ENPP1 | ectonucleotide pyrophosphatase/phosphodiesterase 1 | -0.0137326 |
