| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Omeprazole (sodium) perturbation in HS-578T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Omeprazole (sodium)_HS-578T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.166725 |
| COL6A3 | collagen, type VI, alpha 3 | 0.12855 |
| ATP13A3 | ATPase type 13A3 | 0.0903117 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0864379 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0612542 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0547338 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0519743 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0467781 |
| COL5A1 | collagen, type V, alpha 1 | 0.0439214 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.039016 |
| CALD1 | caldesmon 1 | 0.036188 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0348824 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 | 0.0346444 |
| TFG | TRK-fused gene | 0.0344767 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0344697 |
| DST | dystonin | 0.0323556 |
| CDH13 | cadherin 13 | 0.0320667 |
| LOX | lysyl oxidase | 0.0305283 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0304256 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0302489 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0288566 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0284855 |
| FMNL2 | formin-like 2 | 0.028387 |
| CAVIN1 | caveolae associated protein 1 | 0.0282752 |
| PDLIM5 | PDZ and LIM domain 5 | 0.02823 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0280141 |
| GOLGA4 | golgin A4 | 0.0280054 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0277491 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0274725 |
| RLF | rearranged L-myc fusion | 0.0272267 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.027107 |
| CALR | calreticulin | 0.0265147 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0261355 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.02587 |
| COL4A1 | collagen, type IV, alpha 1 | 0.0258468 |
| PTK2 | protein tyrosine kinase 2 | 0.025768 |
| SDC2 | syndecan 2 | 0.0257351 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0256994 |
| MATR3 | matrin 3 | 0.0252461 |
| ACTG1 | actin gamma 1 | 0.0252034 |
| FOXJ3 | forkhead box J3 | 0.0248812 |
| HSPA8 | heat shock 70kDa protein 8 | 0.024744 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0247218 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | 0.0242809 |
| SPAG9 | sperm associated antigen 9 | 0.0238949 |
| MRTFA | myocardin related transcription factor A | 0.0235945 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0233067 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0228557 |
| RASA2 | RAS p21 protein activator 2 | 0.0228472 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0226814 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0226251 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0224354 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0224144 |
| QKI | QKI, KH domain containing, RNA binding | 0.0222337 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0218734 |
| JAK1 | Janus kinase 1 | 0.0216709 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0215945 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0215659 |
| NUMB | numb homolog (Drosophila) | 0.0214409 |
| CLINT1 | clathrin interactor 1 | 0.0213547 |
| ICAM1 | intercellular adhesion molecule 1 | 0.0212979 |
| DENND5A | DENN/MADD domain containing 5A | 0.0211679 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0208939 |
| ZNF292 | zinc finger protein 292 | 0.0207484 |
| DCAF13 | DDB1 and CUL4 associated factor 13 | 0.0207135 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0206176 |
| RYK | receptor-like tyrosine kinase | 0.0201973 |
| VEGFA | vascular endothelial growth factor A | 0.0196913 |
| PDE10A | phosphodiesterase 10A | 0.0196194 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0196008 |
| RBM39 | RNA binding motif protein 39 | 0.0194992 |
| COL6A2 | collagen, type VI, alpha 2 | 0.0194564 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.019277 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.0191842 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.019101 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | 0.0186027 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0185675 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0183919 |
| RPS2 | ribosomal protein S2 | 0.0183892 |
| TMEM39A | transmembrane protein 39A | 0.0180966 |
| GNAI3 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 | 0.0180962 |
| SAFB2 | scaffold attachment factor B2 | 0.0175335 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0175124 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0174968 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0174551 |
| FAM107B | family with sequence similarity 107, member B | 0.0174379 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0174157 |
| WDR43 | WD repeat domain 43 | 0.0174073 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0173629 |
| TFRC | transferrin receptor | 0.0173422 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0172165 |
| YTHDF3 | YTH N(6)-methyladenosine RNA binding protein 3 | 0.0168354 |
| RPL3 | ribosomal protein L3 | 0.0168335 |
| GLIS3 | GLIS family zinc finger 3 | 0.0166826 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0166247 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0165419 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0164764 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.016457 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0164119 |
| KIF5B | kinesin family member 5B | 0.0163837 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.280089 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.227094 |
| MT2A | metallothionein 2A | -0.197638 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.183559 |
| NDRG1 | N-myc downstream regulated 1 | -0.138182 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.124635 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.107494 |
| TMSB10 | thymosin beta 10 | -0.096194 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0949659 |
| CD44 | CD44 molecule (Indian blood group) | -0.0918254 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0911019 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0854075 |
| B2M | beta-2-microglobulin | -0.0753173 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0706541 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.069861 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0674809 |
| FTL | ferritin, light polypeptide | -0.0647452 |
| ENO1 | enolase 1, (alpha) | -0.0577654 |
| COL1A2 | collagen, type I, alpha 2 | -0.0567644 |
| MAP1B | microtubule-associated protein 1B | -0.0561045 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0555807 |
| HLA-B | major histocompatibility complex, class I, B | -0.0530948 |
| RPL35A | ribosomal protein L35a | -0.051009 |
| LDHA | lactate dehydrogenase A | -0.050696 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0483981 |
| S100A10 | S100 calcium binding protein A10 | -0.0468867 |
| HLA-A | major histocompatibility complex, class I, A | -0.0457388 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0455385 |
| CYB5R3 | cytochrome b5 reductase 3 | -0.0454475 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0450199 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0435395 |
| MT1X | metallothionein 1X | -0.0431262 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0429026 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.042643 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0421585 |
| PFN1 | profilin 1 | -0.0381562 |
| HMGA1 | high mobility group AT-hook 1 | -0.035527 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.033394 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | -0.0333337 |
| IER3 | immediate early response 3 | -0.0329657 |
| AXL | AXL receptor tyrosine kinase | -0.032842 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0327141 |
| TPM4 | tropomyosin 4 | -0.0318139 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0317699 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0316672 |
| COL1A1 | collagen, type I, alpha 1 | -0.0315833 |
| TAPBP | TAP binding protein (tapasin) | -0.0314976 |
| IL6ST | interleukin 6 signal transducer | -0.0307646 |
| RPL19 | ribosomal protein L19 | -0.0305881 |
| ATL1 | atlastin GTPase 1 | -0.0304522 |
| PKM | pyruvate kinase, muscle | -0.0303135 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0302705 |
| RPS19 | ribosomal protein S19 | -0.030115 |
| S100A6 | S100 calcium binding protein A6 | -0.0293732 |
| PERP | PERP, TP53 apoptosis effector | -0.0281445 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0280634 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0280552 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0276591 |
| RPL8 | ribosomal protein L8 | -0.0274865 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0274363 |
| IL6 | interleukin 6 | -0.0264898 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0264687 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0264499 |
| YBX1 | Y box binding protein 1 | -0.0263913 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0260053 |
| PTMA | prothymosin, alpha | -0.0258776 |
| RPS8 | ribosomal protein S8 | -0.0258427 |
| BBX | bobby sox homolog (Drosophila) | -0.0254073 |
| MX2 | MX dynamin-like GTPase 2 | -0.0247334 |
| NRP1 | neuropilin 1 | -0.0241066 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0240178 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0238674 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0235958 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.0234722 |
| ARRDC3 | arrestin domain containing 3 | -0.0233818 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0232638 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0231824 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0230659 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0230002 |
| TPI1 | triosephosphate isomerase 1 | -0.0229865 |
| FOSL1 | FOS-like antigen 1 | -0.022979 |
| UBC | ubiquitin C | -0.0225993 |
| RPS11 | ribosomal protein S11 | -0.0223723 |
| INHBA | inhibin, beta A | -0.0221911 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0219757 |
| RPS14 | ribosomal protein S14 | -0.0219214 |
| RTN4 | reticulon 4 | -0.0218851 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0217588 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | -0.0217012 |
| RPLP0 | ribosomal protein, large, P0 | -0.0216338 |
| CST3 | cystatin C | -0.0215175 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0214951 |
| RPL28 | ribosomal protein L28 | -0.0212976 |
| NUCB2 | nucleobindin 2 | -0.0212816 |
| KLF6 | Kruppel-like factor 6 | -0.0211975 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0208805 |
| CTSB | cathepsin B | -0.0208307 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0206399 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0206085 |
| RPS12 | ribosomal protein S12 | -0.0205944 |
