| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Omeprazole (sodium) perturbation in HT-29 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Omeprazole (sodium)_HT-29 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EXT1 | exostosin glycosyltransferase 1 | 0.0788254 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.0459162 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.0442287 |
| SMAD3 | SMAD family member 3 | 0.0435107 |
| LMO7 | LIM domain 7 | 0.0422729 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0419136 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0367909 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0345019 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0342573 |
| VEGFA | vascular endothelial growth factor A | 0.0330071 |
| FBXO32 | F-box protein 32 | 0.0323823 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0304143 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0290004 |
| FOXO3 | forkhead box O3 | 0.0283646 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.028358 |
| RPS2 | ribosomal protein S2 | 0.0281524 |
| RIGI | RNA sensor RIG-I | 0.0271016 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.025703 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0252063 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0251576 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0248946 |
| FAM13A | family with sequence similarity 13, member A | 0.024886 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0238306 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0232975 |
| GOLGA4 | golgin A4 | 0.0231315 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | 0.0230087 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0225037 |
| TNS1 | tensin 1 | 0.0224872 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | 0.022466 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0222155 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.0221027 |
| FNDC3B | fibronectin type III domain containing 3B | 0.022003 |
| KRT20 | keratin 20, type I | 0.0219693 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.0218674 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | 0.0216694 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0215543 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0215501 |
| SLMAP | sarcolemma associated protein | 0.0210413 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0204944 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0202149 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0198269 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.018722 |
| CNNM2 | cyclin and CBS domain divalent metal cation transport mediator 2 | 0.0183815 |
| ZHX2 | zinc fingers and homeoboxes 2 | 0.0183151 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0182179 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0177428 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0175684 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0175 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0174052 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0172604 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.0171958 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0167446 |
| NEBL | nebulette | 0.0166345 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | 0.0166249 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0164422 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0162956 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0162363 |
| KDM5B | lysine (K)-specific demethylase 5B | 0.0158694 |
| ATAD2 | ATPase family, AAA domain containing 2 | 0.0158506 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | 0.0158484 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | 0.015606 |
| OGA | O-GlcNAcase | 0.0155244 |
| PDE10A | phosphodiesterase 10A | 0.0155132 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.015406 |
| UBA2 | ubiquitin-like modifier activating enzyme 2 | 0.0153301 |
| FAM168A | family with sequence similarity 168, member A | 0.0152664 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0152425 |
| CARS1 | cysteinyl-tRNA synthetase 1 | 0.0152029 |
| ANXA5 | annexin A5 | 0.0151199 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0151046 |
| RASEF | RAS and EF-hand domain containing | 0.0149514 |
| TMEM51 | transmembrane protein 51 | 0.0146301 |
| ZNF292 | zinc finger protein 292 | 0.0146259 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0146226 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0145575 |
| KCMF1 | potassium channel modulatory factor 1 | 0.0143337 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0142603 |
| FBXL20 | F-box and leucine-rich repeat protein 20 | 0.0142234 |
| NPTN | neuroplastin | 0.0141776 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0140354 |
| CRY1 | cryptochrome circadian clock 1 | 0.0139384 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0139094 |
| FOXJ3 | forkhead box J3 | 0.0138805 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | 0.0138156 |
| SEC61G | Sec61 gamma subunit | 0.0138066 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0137957 |
| RNF149 | ring finger protein 149 | 0.0137082 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.0136089 |
| MATR3 | matrin 3 | 0.0135623 |
| TMEM45B | transmembrane protein 45B | 0.0134788 |
| ADM | adrenomedullin | 0.0134263 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.0134238 |
| FBXO11 | F-box protein 11 | 0.0134172 |
| HERC3 | HECT and RLD domain containing E3 ubiquitin protein ligase 3 | 0.0133884 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0133048 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0132325 |
| RPL3 | ribosomal protein L3 | 0.0131343 |
| EPHA2 | EPH receptor A2 | 0.0131308 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0131082 |
| ARRDC3 | arrestin domain containing 3 | 0.0130745 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FTL | ferritin, light polypeptide | -0.163945 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.152617 |
| TXNRD1 | thioredoxin reductase 1 | -0.126139 |
| ANXA2 | annexin A2 | -0.104495 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.0848495 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.084767 |
| PTMA | prothymosin, alpha | -0.0793179 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0788213 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0782447 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0723717 |
| LDHA | lactate dehydrogenase A | -0.0705696 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.070155 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0697043 |
| WASF2 | WAS protein family, member 2 | -0.0696873 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.065817 |
| DST | dystonin | -0.0625066 |
| CANX | calnexin | -0.0613454 |
| AHNAK | AHNAK nucleoprotein | -0.0607343 |
| TMSB10 | thymosin beta 10 | -0.0604604 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0588292 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0576251 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0557002 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0549144 |
| LYZ | lysozyme | -0.0548311 |
| S100A6 | S100 calcium binding protein A6 | -0.052112 |
| KLF3 | Kruppel-like factor 3 (basic) | -0.0519304 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.0505133 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0490027 |
| TRAPPC9 | trafficking protein particle complex 9 | -0.0481527 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0479696 |
| CD2AP | CD2-associated protein | -0.047876 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0475959 |
| KRT8 | keratin 8, type II | -0.0474255 |
| CCNI | cyclin I | -0.0471851 |
| DGKH | diacylglycerol kinase, eta | -0.0465336 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0462038 |
| CSDE1 | cold shock domain containing E1, RNA-binding | -0.0455055 |
| KRT18 | keratin 18, type I | -0.0454378 |
| NSMCE2 | non-SMC element 2, MMS21 homolog (S. cerevisiae) | -0.0450709 |
| TMEM123 | transmembrane protein 123 | -0.0449879 |
| NF1 | neurofibromin 1 | -0.044777 |
| SQSTM1 | sequestosome 1 | -0.0439676 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0436589 |
| ACTN4 | actinin, alpha 4 | -0.0426683 |
| HDLBP | high density lipoprotein binding protein | -0.0423728 |
| ENO1 | enolase 1, (alpha) | -0.0421542 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0419225 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.041259 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | -0.0408677 |
| NECTIN2 | nectin cell adhesion molecule 2 | -0.0406024 |
| THOC2 | THO complex 2 | -0.039988 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | -0.0396517 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0396271 |
| SLC45A4 | solute carrier family 45, member 4 | -0.0393544 |
| DIAPH2 | diaphanous-related formin 2 | -0.039105 |
| TJP1 | tight junction protein 1 | -0.0389953 |
| TKT | transketolase | -0.0379431 |
| EXOC4 | exocyst complex component 4 | -0.0378881 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0373496 |
| PERP | PERP, TP53 apoptosis effector | -0.0366703 |
| JUN | jun proto-oncogene | -0.0363447 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0362097 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.0356647 |
| RPL27A | ribosomal protein L27a | -0.0354809 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0354681 |
| ACACA | acetyl-CoA carboxylase alpha | -0.0351073 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0350693 |
| KLF12 | Kruppel-like factor 12 | -0.0348383 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.034638 |
| TRAM1 | translocation associated membrane protein 1 | -0.0345685 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0344923 |
| PGK1 | phosphoglycerate kinase 1 | -0.0344011 |
| ITPKC | inositol-trisphosphate 3-kinase C | -0.0341357 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type | -0.034114 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.0338919 |
| RPL23 | ribosomal protein L23 | -0.0338204 |
| LGALS4 | lectin, galactoside-binding, soluble, 4 | -0.0337789 |
| BPTF | bromodomain PHD finger transcription factor | -0.0335128 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0332723 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0331032 |
| ITGA6 | integrin, alpha 6 | -0.0330982 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0326201 |
| RPL19 | ribosomal protein L19 | -0.0325795 |
| EGR1 | early growth response 1 | -0.0322076 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0320674 |
| C6ORF132 | chromosome 6 open reading frame 132 | -0.0318693 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0318025 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0313704 |
| SLC38A2 | solute carrier family 38, member 2 | -0.03118 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.0307063 |
| ATXN1 | ataxin 1 | -0.030697 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | -0.0305573 |
| PTK2 | protein tyrosine kinase 2 | -0.0304895 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0302624 |
| CHD9 | chromodomain helicase DNA binding protein 9 | -0.0300985 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0300864 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0299695 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0298112 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0298084 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0296331 |
