| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Omeprazole (sodium) perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Omeprazole (sodium)_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DST | dystonin | 0.0456258 |
| POTEF | POTE ankyrin domain family, member F | 0.0409238 |
| CAPRIN2 | caprin family member 2 | 0.0386673 |
| PIAS2 | protein inhibitor of activated STAT, 2 | 0.0374764 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0324192 |
| PCDH1 | protocadherin 1 | 0.028331 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0275664 |
| SLK | STE20-like kinase | 0.0266703 |
| PRELID2 | PRELI domain containing 2 | 0.023987 |
| CCNL1 | cyclin L1 | 0.0223936 |
| ZNF292 | zinc finger protein 292 | 0.021796 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.0216413 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0213746 |
| MEF2A | myocyte enhancer factor 2A | 0.0199469 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0198231 |
| HELZ | helicase with zinc finger | 0.0192918 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0189114 |
| MSN | moesin | 0.0188272 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.018082 |
| VEGFA | vascular endothelial growth factor A | 0.0178497 |
| FNIP1 | folliculin interacting protein 1 | 0.0178327 |
| RPL3 | ribosomal protein L3 | 0.0169064 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0168876 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0167916 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0166222 |
| HSPG2 | heparan sulfate proteoglycan 2 | 0.0163855 |
| DDX41 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 41 | 0.0162985 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0161722 |
| DOCK11 | dedicator of cytokinesis 11 | 0.0161635 |
| FMNL2 | formin-like 2 | 0.0161286 |
| CSMD3 | CUB and Sushi multiple domains 3 | 0.015731 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.015589 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.0155771 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0155451 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0154571 |
| RAD51B | RAD51 paralog B | 0.0152112 |
| ARRDC3 | arrestin domain containing 3 | 0.0151344 |
| HDGF | hepatoma-derived growth factor | 0.0150913 |
| RPS2 | ribosomal protein S2 | 0.0146611 |
| RNF145 | ring finger protein 145 | 0.0145755 |
| EGFR | epidermal growth factor receptor | 0.0145485 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0145361 |
| ZNF148 | zinc finger protein 148 | 0.0145154 |
| GNGT1 | guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 | 0.0136952 |
| GOLGA4 | golgin A4 | 0.0134038 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0132947 |
| PLOD1 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 | 0.01319 |
| ZMIZ2 | zinc finger, MIZ-type containing 2 | 0.0131706 |
| SETD5 | SET domain containing 5 | 0.0130671 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.012872 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0126587 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0126503 |
| PRPF8 | pre-mRNA processing factor 8 | 0.0126212 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0125333 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0124026 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0124023 |
| SBF2 | SET binding factor 2 | 0.0122943 |
| ATN1 | atrophin 1 | 0.012243 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0121171 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.01205 |
| LYST | lysosomal trafficking regulator | 0.0119997 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0116568 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0115823 |
| CDK19 | cyclin-dependent kinase 19 | 0.0115091 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | 0.0114926 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | 0.0114336 |
| CD109 | CD109 molecule | 0.0114256 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0114196 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | 0.0114136 |
| PKM | pyruvate kinase, muscle | 0.0113961 |
| TPRG1 | tumor protein p63 regulated 1 | 0.0113753 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0113689 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0113598 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0113331 |
| RPS12 | ribosomal protein S12 | 0.0112135 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 | 0.0111329 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0110713 |
| TNS3 | tensin 3 | 0.0110002 |
| AHDC1 | AT hook, DNA binding motif, containing 1 | 0.0109112 |
| TRERF1 | transcriptional regulating factor 1 | 0.0108203 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0107454 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0106942 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.01069 |
| YEATS2 | YEATS domain containing 2 | 0.0106455 |
| LENG8 | leukocyte receptor cluster (LRC) member 8 | 0.0103492 |
| FBXL5 | F-box and leucine-rich repeat protein 5 | 0.0103465 |
| FOXN3 | forkhead box N3 | 0.0102444 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0101152 |
| TGM2 | transglutaminase 2 | 0.0100326 |
| ANKRD36B | ankyrin repeat domain 36B | 0.0100255 |
| PFN1 | profilin 1 | 0.00998795 |
| AGRN | agrin | 0.00995017 |
| NUP58 | nucleoporin 58 | 0.00994675 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.00992381 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.00991146 |
| RNPS1 | RNA binding protein S1, serine-rich domain | 0.00989801 |
| WDR43 | WD repeat domain 43 | 0.00985588 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.00983564 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | 0.00982009 |
| PPP1R12B | protein phosphatase 1, regulatory subunit 12B | 0.00971659 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.259101 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.238476 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.167502 |
| TXNRD1 | thioredoxin reductase 1 | -0.149991 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.131806 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.110678 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.102874 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0955599 |
| TMSB10 | thymosin beta 10 | -0.0900705 |
| AHNAK | AHNAK nucleoprotein | -0.0853328 |
| CD44 | CD44 molecule (Indian blood group) | -0.082541 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0807286 |
| CANX | calnexin | -0.0781829 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0761908 |
| TMSB4X | thymosin beta 4, X-linked | -0.0754334 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0713463 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0692901 |
| MT2A | metallothionein 2A | -0.0672214 |
| RAI1 | retinoic acid induced 1 | -0.0646579 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0630814 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.059118 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0566189 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0543218 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0531528 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.0522498 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0516838 |
| GCLM | glutamate-cysteine ligase, modifier subunit | -0.0491451 |
| HDLBP | high density lipoprotein binding protein | -0.0483054 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0470659 |
| TP63 | tumor protein p63 | -0.0464706 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0457473 |
| SLC38A2 | solute carrier family 38, member 2 | -0.044983 |
| APP | amyloid beta (A4) precursor protein | -0.0449765 |
| HLA-B | major histocompatibility complex, class I, B | -0.0446085 |
| RGS4 | regulator of G-protein signaling 4 | -0.0427929 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.041246 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.0409913 |
| RPS24 | ribosomal protein S24 | -0.0407141 |
| KPNB1 | karyopherin (importin) beta 1 | -0.039314 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | -0.0384754 |
| RPL35A | ribosomal protein L35a | -0.0383004 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0374413 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0369498 |
| ZNF217 | zinc finger protein 217 | -0.0369093 |
| ACTG1 | actin gamma 1 | -0.0361577 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0360941 |
| LDHA | lactate dehydrogenase A | -0.0344606 |
| RUNX1 | runt-related transcription factor 1 | -0.033659 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0334142 |
| VDAC1 | voltage-dependent anion channel 1 | -0.032744 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0309011 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0305119 |
| JMJD1C | jumonji domain containing 1C | -0.0305042 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0298302 |
| SRGN | serglycin | -0.0296969 |
| RIGI | RNA sensor RIG-I | -0.0296633 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0293993 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0292635 |
| RPLP1 | ribosomal protein, large, P1 | -0.029212 |
| USP34 | ubiquitin specific peptidase 34 | -0.0291707 |
| PRRC2B | proline-rich coiled-coil 2B | -0.0291158 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0289495 |
| ARF1 | ADP-ribosylation factor 1 | -0.0289492 |
| ANXA2 | annexin A2 | -0.0288422 |
| SP100 | SP100 nuclear antigen | -0.028815 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0281558 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0280919 |
| CMIP | c-Maf inducing protein | -0.027286 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0272699 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0269701 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 | -0.0266313 |
| EHBP1 | EH domain binding protein 1 | -0.0266127 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0265488 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0264409 |
| EREG | epiregulin | -0.0264391 |
| RPL36A | ribosomal protein L36a | -0.026245 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0261018 |
| RPS19 | ribosomal protein S19 | -0.0258535 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | -0.0258197 |
| ENO1 | enolase 1, (alpha) | -0.0255732 |
| RPL19 | ribosomal protein L19 | -0.0255654 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0254946 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0254814 |
| RPS8 | ribosomal protein S8 | -0.0252572 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0252422 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0249535 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0248877 |
| YBX3 | Y box binding protein 3 | -0.0248754 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.0248652 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0247515 |
| FBXO11 | F-box protein 11 | -0.02463 |
| TMEM41B | transmembrane protein 41B | -0.0245709 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.024481 |
| SLC38A1 | solute carrier family 38, member 1 | -0.024384 |
| JUN | jun proto-oncogene | -0.0243593 |
| TRIP12 | thyroid hormone receptor interactor 12 | -0.0240785 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0239173 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | -0.0238957 |
| CDK13 | cyclin-dependent kinase 13 | -0.0238405 |
| KLF6 | Kruppel-like factor 6 | -0.0236098 |
