| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Omeprazole (sodium) perturbation in NCI-H1573 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Omeprazole (sodium)_NCI-H1573 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EGFR | epidermal growth factor receptor | 0.136408 |
| LAMC2 | laminin, gamma 2 | 0.104549 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.100762 |
| NDRG1 | N-myc downstream regulated 1 | 0.0891994 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0835372 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | 0.0810968 |
| FAM13A | family with sequence similarity 13, member A | 0.0790823 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0553952 |
| SMAD3 | SMAD family member 3 | 0.0504566 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0489886 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0470054 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.046846 |
| PDE8A | phosphodiesterase 8A | 0.0463464 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0455384 |
| MSN | moesin | 0.0443822 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0429779 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0406622 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0400402 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0392867 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0392776 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0391729 |
| ZNF292 | zinc finger protein 292 | 0.0380559 |
| ATP13A3 | ATPase type 13A3 | 0.0377107 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.03754 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0372825 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | 0.034976 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0346604 |
| POTEF | POTE ankyrin domain family, member F | 0.0335483 |
| CAV2 | caveolin 2 | 0.0324547 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | 0.0318199 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0314366 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0308847 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0304141 |
| TNFAIP8 | tumor necrosis factor, alpha-induced protein 8 | 0.0303767 |
| KCMF1 | potassium channel modulatory factor 1 | 0.0298853 |
| LANCL2 | LanC lantibiotic synthetase component C-like 2 (bacterial) | 0.0298761 |
| FBXL5 | F-box and leucine-rich repeat protein 5 | 0.0286016 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0283387 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | 0.0276534 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0274883 |
| SETD5 | SET domain containing 5 | 0.0271785 |
| RASA2 | RAS p21 protein activator 2 | 0.0266732 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.0264837 |
| NCKAP1 | NCK-associated protein 1 | 0.0263714 |
| SBF2 | SET binding factor 2 | 0.0259387 |
| LRP1B | low density lipoprotein receptor-related protein 1B | 0.025822 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0255661 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0251378 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0249476 |
| RNF145 | ring finger protein 145 | 0.0249393 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.024733 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.0245641 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0243958 |
| CDCP1 | CUB domain containing protein 1 | 0.0241618 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0238488 |
| ARRDC3 | arrestin domain containing 3 | 0.0235524 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0235244 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0235135 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0234596 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0232979 |
| CDKN2A | cyclin-dependent kinase inhibitor 2A | 0.023022 |
| FLNB | filamin B, beta | 0.0230033 |
| VEGFA | vascular endothelial growth factor A | 0.0229649 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0226687 |
| GPC6 | glypican 6 | 0.0226143 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0225378 |
| SLMAP | sarcolemma associated protein | 0.0225024 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0221559 |
| NDUFV2 | NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa | 0.0220828 |
| SEC61G | Sec61 gamma subunit | 0.0218328 |
| ITGA6 | integrin, alpha 6 | 0.0215396 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0213882 |
| TM9SF2 | transmembrane 9 superfamily member 2 | 0.0212076 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0210966 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0209519 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0206068 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.0205772 |
| GOLGA4 | golgin A4 | 0.0204505 |
| OFD1 | oral-facial-digital syndrome 1 | 0.0204489 |
| TPD52 | tumor protein D52 | 0.0201342 |
| FERMT1 | fermitin family member 1 | 0.02001 |
| SLK | STE20-like kinase | 0.0200035 |
| DIP2B | DIP2 disco-interacting protein 2 homolog B (Drosophila) | 0.0198497 |
| RNF149 | ring finger protein 149 | 0.0197676 |
| CYLD | cylindromatosis (turban tumor syndrome) | 0.0196753 |
| FA2H | fatty acid 2-hydroxylase | 0.0194995 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0193159 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.0191711 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0191456 |
| AMOTL1 | angiomotin like 1 | 0.0190582 |
| ITSN2 | intersectin 2 | 0.0190025 |
| MXD1 | MAX dimerization protein 1 | 0.0189643 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0188879 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.0188298 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.0185199 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.0183025 |
| SPIRE1 | spire-type actin nucleation factor 1 | 0.0183009 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0181382 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0178423 |
| ACTN1 | actinin, alpha 1 | 0.0176904 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.181574 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.104683 |
| TXNRD1 | thioredoxin reductase 1 | -0.0972863 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0838643 |
| CANX | calnexin | -0.0746392 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0685126 |
| AGO2 | argonaute RISC catalytic component 2 | -0.0637855 |
| NABP1 | nucleic acid binding protein 1 | -0.0632704 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0597007 |
| HDLBP | high density lipoprotein binding protein | -0.0592026 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0580059 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0546661 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0514066 |
| AHNAK | AHNAK nucleoprotein | -0.0485027 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0470509 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0466796 |
| ANXA2 | annexin A2 | -0.046331 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0455869 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0435316 |
| TRAPPC9 | trafficking protein particle complex 9 | -0.0430823 |
| RPLP1 | ribosomal protein, large, P1 | -0.0422749 |
| RPLP0 | ribosomal protein, large, P0 | -0.0420111 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0416687 |
| INTS6 | integrator complex subunit 6 | -0.0409725 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0405961 |
| GM2A | GM2 ganglioside activator | -0.0395987 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0395224 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0390317 |
| H1-0 | H1.0 linker histone | -0.0387489 |
| ZC3H11A | zinc finger CCCH-type containing 11A | -0.0384422 |
| RPS24 | ribosomal protein S24 | -0.0384291 |
| RPS3 | ribosomal protein S3 | -0.0379645 |
| TMCO3 | transmembrane and coiled-coil domains 3 | -0.0354451 |
| EFNA5 | ephrin-A5 | -0.0351151 |
| ABLIM1 | actin binding LIM protein 1 | -0.0347502 |
| FTL | ferritin, light polypeptide | -0.0342806 |
| RPL34 | ribosomal protein L34 | -0.0334397 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | -0.0322825 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0321581 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0317759 |
| SP100 | SP100 nuclear antigen | -0.0317003 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0307968 |
| NSUN6 | NOP2/Sun domain family, member 6 | -0.030375 |
| ANKLE2 | ankyrin repeat and LEM domain containing 2 | -0.0296331 |
| RPL11 | ribosomal protein L11 | -0.0296312 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0296246 |
| MORF4L2 | mortality factor 4 like 2 | -0.0287881 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.02835 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.028173 |
| SCLT1 | sodium channel and clathrin linker 1 | -0.0276521 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.027629 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0276122 |
| RNF169 | ring finger protein 169 | -0.0274031 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0273967 |
| SMYD3 | SET and MYND domain containing 3 | -0.0273766 |
| RPL35A | ribosomal protein L35a | -0.0273297 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0268425 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.026816 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0262734 |
| CCND1 | cyclin D1 | -0.0259509 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0255247 |
| RNF213 | ring finger protein 213 | -0.0254784 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0254013 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0253263 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0249183 |
| MGAT4C | MGAT4 family, member C | -0.0248275 |
| SMIM14 | small integral membrane protein 14 | -0.0245586 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0244298 |
| RPS25 | ribosomal protein S25 | -0.0243515 |
| ANKRD10 | ankyrin repeat domain 10 | -0.024337 |
| LAMB3 | laminin, beta 3 | -0.0243098 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0242893 |
| XRRA1 | X-ray radiation resistance associated 1 | -0.0242859 |
| TRIM56 | tripartite motif containing 56 | -0.0241706 |
| LRP12 | low density lipoprotein receptor-related protein 12 | -0.024113 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | -0.024091 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0238132 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0233002 |
| GOLGB1 | golgin B1 | -0.0232674 |
| EXOC6B | exocyst complex component 6B | -0.0229919 |
| MGST1 | microsomal glutathione S-transferase 1 | -0.0229514 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0229228 |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) | -0.0228376 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0223487 |
| EMP1 | epithelial membrane protein 1 | -0.022292 |
| EYA2 | EYA transcriptional coactivator and phosphatase 2 | -0.0222455 |
| HOMER1 | homer scaffolding protein 1 | -0.0221668 |
| IRS2 | insulin receptor substrate 2 | -0.0221287 |
| UGGT2 | UDP-glucose glycoprotein glucosyltransferase 2 | -0.0218815 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0218127 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0217104 |
| PM20D1 | peptidase M20 domain containing 1 | -0.0216887 |
| TPTEP2-CSNK1E | TPTEP2-CSNK1E readthrough | -0.0214624 |
| FOXP1 | forkhead box P1 | -0.0212925 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | -0.0211737 |
| FAAH2 | fatty acid amide hydrolase 2 | -0.0210915 |
| ARF1 | ADP-ribosylation factor 1 | -0.0210836 |
| AEBP2 | AE binding protein 2 | -0.0206299 |
| ADAM32 | ADAM metallopeptidase domain 32 | -0.0204566 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0204498 |
