| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Omeprazole (sodium) perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Omeprazole (sodium)_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LOX | lysyl oxidase | 0.152247 |
| GRB10 | growth factor receptor-bound protein 10 | 0.10854 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 0.0910045 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0896858 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0878462 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0859688 |
| TMSB10 | thymosin beta 10 | 0.0817575 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0793649 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0726594 |
| FAM20C | family with sequence similarity 20, member C | 0.0620676 |
| VIM | vimentin | 0.05777 |
| VEGFA | vascular endothelial growth factor A | 0.0566065 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.05492 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0548804 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0534355 |
| HMGA2 | high mobility group AT-hook 2 | 0.0533546 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0523552 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0521735 |
| FN1 | fibronectin 1 | 0.0509983 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0496825 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0487686 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0474345 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 0.046836 |
| RNF145 | ring finger protein 145 | 0.0459553 |
| SFTPA2 | surfactant protein A2 | 0.0443148 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0439767 |
| NAV2 | neuron navigator 2 | 0.0439725 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0433393 |
| EGFR | epidermal growth factor receptor | 0.0419068 |
| SIK3 | SIK family kinase 3 | 0.041875 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0410832 |
| NDRG1 | N-myc downstream regulated 1 | 0.0407491 |
| NGLY1 | N-glycanase 1 | 0.0398223 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0387936 |
| ATP13A3 | ATPase type 13A3 | 0.0386236 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | 0.0381743 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0369488 |
| ADM | adrenomedullin | 0.036495 |
| MEMO1 | mediator of cell motility 1 | 0.0361764 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0357735 |
| ACTN4 | actinin, alpha 4 | 0.0349941 |
| TGM2 | transglutaminase 2 | 0.0342317 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0340791 |
| NPC1 | Niemann-Pick disease, type C1 | 0.0334241 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0331067 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.032994 |
| CALR | calreticulin | 0.0329452 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.032393 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0316139 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0312977 |
| STAM | signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 | 0.0305767 |
| SETD5 | SET domain containing 5 | 0.0303195 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.030317 |
| TOP1 | topoisomerase (DNA) I | 0.0298073 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0296123 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0293152 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0286027 |
| STC1 | stanniocalcin 1 | 0.0279976 |
| RAP1B | RAP1B, member of RAS oncogene family | 0.0277101 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0276464 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0269421 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0268644 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | 0.0266073 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0264622 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0264282 |
| PDGFA | platelet-derived growth factor alpha polypeptide | 0.0263336 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0262617 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0260564 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.026 |
| GREB1L | growth regulation by estrogen in breast cancer-like | 0.0252591 |
| MAX | MYC associated factor X | 0.0252011 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.0250788 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0248901 |
| MMP2 | matrix metallopeptidase 2 | 0.0245528 |
| PGK1 | phosphoglycerate kinase 1 | 0.0239693 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0238339 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0231834 |
| PDLIM5 | PDZ and LIM domain 5 | 0.023156 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0230941 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0230126 |
| CSNK1G1 | casein kinase 1, gamma 1 | 0.0225126 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0223613 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 0.0221762 |
| TMTC1 | transmembrane and tetratricopeptide repeat containing 1 | 0.0218835 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0218829 |
| POTEF | POTE ankyrin domain family, member F | 0.0217539 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0216053 |
| USP53 | ubiquitin specific peptidase 53 | 0.0214402 |
| DPM1 | dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit | 0.0211599 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0210753 |
| MT2A | metallothionein 2A | 0.0209706 |
| OXSR1 | oxidative stress responsive 1 | 0.0208679 |
| EGR1 | early growth response 1 | 0.0208592 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | 0.020787 |
| RAB18 | RAB18, member RAS oncogene family | 0.0206847 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0206034 |
| FLNB | filamin B, beta | 0.0205626 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | 0.0204808 |
| FOXO3 | forkhead box O3 | 0.0204006 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0203214 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.281 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.25236 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.14775 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0962733 |
| PCBP2 | poly(rC) binding protein 2 | -0.0961765 |
| CANX | calnexin | -0.0914155 |
| CD44 | CD44 molecule (Indian blood group) | -0.0856284 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0827542 |
| AHNAK | AHNAK nucleoprotein | -0.071589 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0698497 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0685521 |
| USP34 | ubiquitin specific peptidase 34 | -0.0655988 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0636284 |
| FTL | ferritin, light polypeptide | -0.0630176 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0595287 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0575776 |
| RBM39 | RNA binding motif protein 39 | -0.0572328 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.052801 |
| RAD51B | RAD51 paralog B | -0.0522231 |
| SMAD3 | SMAD family member 3 | -0.0521537 |
| TXNRD1 | thioredoxin reductase 1 | -0.0494633 |
| PTMA | prothymosin, alpha | -0.0480768 |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) | -0.0480049 |
| ASPH | aspartate beta-hydroxylase | -0.0454478 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0451126 |
| RPS24 | ribosomal protein S24 | -0.0449521 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0437308 |
| NRG1 | neuregulin 1 | -0.0432914 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0430148 |
| LRP1B | low density lipoprotein receptor-related protein 1B | -0.0425048 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.041639 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0411174 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.041062 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0409299 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0407756 |
| PNPT1 | polyribonucleotide nucleotidyltransferase 1 | -0.0402834 |
| H1-0 | H1.0 linker histone | -0.0398403 |
| GPC6 | glypican 6 | -0.039034 |
| HDLBP | high density lipoprotein binding protein | -0.0388932 |
| EREG | epiregulin | -0.0387644 |
| B2M | beta-2-microglobulin | -0.0381429 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0378476 |
| TMEM263 | transmembrane protein 263 | -0.0375807 |
| UGP2 | UDP-glucose pyrophosphorylase 2 | -0.0372498 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0367054 |
| ETV6 | ets variant 6 | -0.0363602 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0363232 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0360284 |
| XPO1 | exportin 1 | -0.0358102 |
| OGA | O-GlcNAcase | -0.0354262 |
| MAN2A1 | mannosidase, alpha, class 2A, member 1 | -0.0352925 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0345512 |
| MORF4L2 | mortality factor 4 like 2 | -0.0338709 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0338579 |
| ADAR | adenosine deaminase, RNA-specific | -0.0337248 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0336245 |
| RPLP0 | ribosomal protein, large, P0 | -0.0332975 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0330012 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0327735 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0323231 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0321327 |
| ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 | -0.0319569 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0318021 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0316628 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | -0.0315422 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0314928 |
| FAM13A | family with sequence similarity 13, member A | -0.0314841 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0311114 |
| ZFP91 | ZFP91 zinc finger protein | -0.0304264 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0303879 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0299765 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0299023 |
| PTK2 | protein tyrosine kinase 2 | -0.0298375 |
| RPS11 | ribosomal protein S11 | -0.0298136 |
| GNGT1 | guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 | -0.0298093 |
| RPL7 | ribosomal protein L7 | -0.0294852 |
| ANXA1 | annexin A1 | -0.0294666 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0285945 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.028513 |
| MIB1 | mindbomb E3 ubiquitin protein ligase 1 | -0.0278609 |
| SLFN5 | schlafen family member 5 | -0.0277979 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.027593 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0275157 |
| EXOC4 | exocyst complex component 4 | -0.0273982 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0273141 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0271745 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0270248 |
| PLA2G4A | phospholipase A2, group IVA (cytosolic, calcium-dependent) | -0.0268972 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0268594 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | -0.0268163 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0264406 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0262463 |
| UMAD1 | UBAP1-MVB12-associated (UMA) domain containing 1 | -0.0261728 |
| NTN4 | netrin 4 | -0.0261352 |
| YBX1 | Y box binding protein 1 | -0.0259086 |
| CDCP1 | CUB domain containing protein 1 | -0.0258254 |
| RPS2 | ribosomal protein S2 | -0.0252895 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0252387 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0252328 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0251283 |
