| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Omeprazole (sodium) perturbation in NCI-H2030 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Omeprazole (sodium)_NCI-H2030 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GRAMD1B | GRAM domain containing 1B | 0.242829 |
| TXNRD1 | thioredoxin reductase 1 | 0.200603 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.137633 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.133514 |
| PM20D1 | peptidase M20 domain containing 1 | 0.120453 |
| WDR43 | WD repeat domain 43 | 0.0720333 |
| FGB | fibrinogen beta chain | 0.0648605 |
| RTN4 | reticulon 4 | 0.0632645 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0632033 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.05595 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.055131 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0538466 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.053677 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0535961 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0482614 |
| USP3 | ubiquitin specific peptidase 3 | 0.0470094 |
| PTP4A1 | protein tyrosine phosphatase type IVA, member 1 | 0.0455413 |
| CCNL1 | cyclin L1 | 0.0452361 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0449522 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0443525 |
| HDAC9 | histone deacetylase 9 | 0.0411301 |
| TPM3 | tropomyosin 3 | 0.0393535 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0387758 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.0382268 |
| YBX3 | Y box binding protein 3 | 0.0381693 |
| ZNF292 | zinc finger protein 292 | 0.0381682 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0381066 |
| PLS3 | plastin 3 | 0.0380428 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0375636 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.036506 |
| FAM168A | family with sequence similarity 168, member A | 0.036409 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0362222 |
| ECT2 | epithelial cell transforming 2 | 0.0361998 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.0361592 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0358618 |
| ARL5B | ADP-ribosylation factor-like 5B | 0.0352878 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0348926 |
| TPD52 | tumor protein D52 | 0.034495 |
| NUP58 | nucleoporin 58 | 0.0344826 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0342908 |
| MKI67 | marker of proliferation Ki-67 | 0.0342125 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0340918 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0329859 |
| TFG | TRK-fused gene | 0.0324449 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0318112 |
| POTEF | POTE ankyrin domain family, member F | 0.0316365 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0315577 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0312992 |
| CCT5 | chaperonin containing TCP1, subunit 5 (epsilon) | 0.0312616 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0309622 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0309466 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | 0.0309361 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0309314 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | 0.0299134 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0297528 |
| YBX1 | Y box binding protein 1 | 0.0288934 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0284846 |
| CHN1 | chimerin 1 | 0.0279252 |
| PAWR | PRKC, apoptosis, WT1, regulator | 0.0277722 |
| PFN1 | profilin 1 | 0.0276702 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0273811 |
| SPAG9 | sperm associated antigen 9 | 0.0272501 |
| THBS1 | thrombospondin 1 | 0.0271755 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0270405 |
| RFWD3 | ring finger and WD repeat domain 3 | 0.0267849 |
| WBP11 | WW domain binding protein 11 | 0.0259295 |
| MSN | moesin | 0.0258384 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | 0.0257691 |
| TRA2B | transformer 2 beta homolog (Drosophila) | 0.02541 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | 0.0252801 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0252738 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0249347 |
| PFDN2 | prefoldin subunit 2 | 0.0249054 |
| PTK2 | protein tyrosine kinase 2 | 0.0248754 |
| RNF145 | ring finger protein 145 | 0.0248536 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | 0.0242291 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0241017 |
| SIN3A | SIN3 transcription regulator family member A | 0.0239429 |
| XPO1 | exportin 1 | 0.0239405 |
| LAMB1 | laminin, beta 1 | 0.0236138 |
| CYRIB | CYFIP related Rac1 interactor B | 0.0236049 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0235369 |
| TAGLN2 | transgelin 2 | 0.0234036 |
| FGA | fibrinogen alpha chain | 0.0229097 |
| NCKAP1 | NCK-associated protein 1 | 0.0228812 |
| TCERG1 | transcription elongation regulator 1 | 0.0228596 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | 0.0227309 |
| MTMR3 | myotubularin related protein 3 | 0.0225534 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0223865 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0223466 |
| TMEM123 | transmembrane protein 123 | 0.0222914 |
| FGG | fibrinogen gamma chain | 0.0220988 |
| NOLC1 | nucleolar and coiled-body phosphoprotein 1 | 0.022078 |
| ANLN | anillin, actin binding protein | 0.0220736 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0218185 |
| JAK1 | Janus kinase 1 | 0.021707 |
| TMED10 | transmembrane emp24-like trafficking protein 10 (yeast) | 0.021553 |
| PFKP | phosphofructokinase, platelet | 0.0214222 |
| MEMO1 | mediator of cell motility 1 | 0.0213307 |
| XRCC5 | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) | 0.021315 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | -0.225304 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.179432 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.159227 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.148969 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.100528 |
| VIM | vimentin | -0.0933284 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0929754 |
| TMSB10 | thymosin beta 10 | -0.0880023 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0829545 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0819022 |
| IER3 | immediate early response 3 | -0.0753025 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0648774 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0609464 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0606594 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0605461 |
| HLA-B | major histocompatibility complex, class I, B | -0.0583963 |
| RPS8 | ribosomal protein S8 | -0.0577039 |
| S100A6 | S100 calcium binding protein A6 | -0.0561089 |
| AHNAK | AHNAK nucleoprotein | -0.0537955 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0528718 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0501264 |
| SMOC1 | SPARC related modular calcium binding 1 | -0.0493031 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.049153 |
| FTL | ferritin, light polypeptide | -0.0475015 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0463147 |
| RPL23 | ribosomal protein L23 | -0.0451366 |
| EGFR | epidermal growth factor receptor | -0.0450385 |
| S100A10 | S100 calcium binding protein A10 | -0.0448792 |
| INTS6 | integrator complex subunit 6 | -0.0432158 |
| VCL | vinculin | -0.0428727 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.04261 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0420652 |
| RPL35A | ribosomal protein L35a | -0.0414163 |
| RPL19 | ribosomal protein L19 | -0.0403444 |
| ATXN1 | ataxin 1 | -0.0399192 |
| MYO1E | myosin IE | -0.0393363 |
| RPLP1 | ribosomal protein, large, P1 | -0.038773 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | -0.0381613 |
| FMNL2 | formin-like 2 | -0.0381497 |
| PCNX4 | pecanex 4 | -0.0375939 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0372696 |
| MORF4L2 | mortality factor 4 like 2 | -0.0371965 |
| RPL31 | ribosomal protein L31 | -0.0371395 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | -0.0365667 |
| KYNU | kynureninase | -0.0361782 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0358769 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | -0.0354442 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0351883 |
| NF1 | neurofibromin 1 | -0.0351068 |
| RPL37A | ribosomal protein L37a | -0.0348489 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0346072 |
| SQSTM1 | sequestosome 1 | -0.0342946 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0340146 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0334862 |
| RPL34 | ribosomal protein L34 | -0.0327416 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0323659 |
| PYGL | phosphorylase, glycogen, liver | -0.0316747 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0315603 |
| CAVIN1 | caveolae associated protein 1 | -0.0314339 |
| RPS24 | ribosomal protein S24 | -0.0310381 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0308511 |
| HLA-E | major histocompatibility complex, class I, E | -0.0305045 |
| RPS27A | ribosomal protein S27a | -0.0300611 |
| GNAS | GNAS complex locus | -0.0299958 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.029832 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0297286 |
| RPS25 | ribosomal protein S25 | -0.0292762 |
| CDK13 | cyclin-dependent kinase 13 | -0.0288567 |
| CUX1 | cut-like homeobox 1 | -0.028765 |
| HLA-A | major histocompatibility complex, class I, A | -0.0280512 |
| SNX14 | sorting nexin 14 | -0.0280402 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0277474 |
| ACTG1 | actin gamma 1 | -0.0271408 |
| NUMB | numb homolog (Drosophila) | -0.0269279 |
| NHSL1 | NHS-like 1 | -0.0268549 |
| CMIP | c-Maf inducing protein | -0.0265839 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0265054 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0262943 |
| RPS16 | ribosomal protein S16 | -0.0261889 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 | -0.0261616 |
| CTBP2 | C-terminal binding protein 2 | -0.0261086 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | -0.0260338 |
| NDRG1 | N-myc downstream regulated 1 | -0.0257492 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0257204 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0257017 |
| MCL1 | myeloid cell leukemia 1 | -0.0256896 |
| ATG7 | autophagy related 7 | -0.0255683 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0255331 |
| NLK | nemo-like kinase | -0.025456 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | -0.0253114 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0252111 |
| HMGA2 | high mobility group AT-hook 2 | -0.0251289 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0249474 |
| LRCH3 | leucine-rich repeats and calponin homology (CH) domain containing 3 | -0.0246591 |
| MSRB3 | methionine sulfoxide reductase B3 | -0.0246296 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0245003 |
| RPL9 | ribosomal protein L9 | -0.024441 |
| CFDP1 | craniofacial development protein 1 | -0.0243409 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0242568 |
| RPL11 | ribosomal protein L11 | -0.0242551 |
