| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Omeprazole (sodium) perturbation in NCI-H2122 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Omeprazole (sodium)_NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL5A2 | collagen, type V, alpha 2 | 0.0761995 |
| EFNA5 | ephrin-A5 | 0.0708909 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0650852 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0590693 |
| FRMD4A | FERM domain containing 4A | 0.0589461 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.0586386 |
| RLF | rearranged L-myc fusion | 0.0579551 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0569766 |
| UBC | ubiquitin C | 0.0542065 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.0539024 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0533622 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0517612 |
| SLTM | SAFB-like, transcription modulator | 0.0515293 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0478111 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0475438 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0472429 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0467917 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0461752 |
| TENM3 | teneurin transmembrane protein 3 | 0.0454213 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0446172 |
| QKI | QKI, KH domain containing, RNA binding | 0.0442892 |
| P3H2 | prolyl 3-hydroxylase 2 | 0.0441558 |
| NFIA | nuclear factor I/A | 0.0431368 |
| PNPLA8 | patatin-like phospholipase domain containing 8 | 0.0424969 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0422943 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0416684 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0410436 |
| B2M | beta-2-microglobulin | 0.0401154 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0395805 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0392543 |
| DST | dystonin | 0.0392333 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | 0.038401 |
| RPS3 | ribosomal protein S3 | 0.0381995 |
| MATR3 | matrin 3 | 0.0381028 |
| THOC2 | THO complex 2 | 0.037089 |
| HDLBP | high density lipoprotein binding protein | 0.0369581 |
| SEPTIN7 | septin 7 | 0.036955 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0365573 |
| CELF1 | CUGBP, Elav-like family member 1 | 0.0363457 |
| KMT2A | lysine (K)-specific methyltransferase 2A | 0.0363023 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0359609 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0358395 |
| PDPK1 | 3-phosphoinositide dependent protein kinase 1 | 0.0357182 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.0355401 |
| ITGA6 | integrin, alpha 6 | 0.0354845 |
| RAD21 | RAD21 homolog (S. pombe) | 0.035297 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0351993 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | 0.0351421 |
| LMBR1 | limb development membrane protein 1 | 0.03509 |
| RBM25 | RNA binding motif protein 25 | 0.0349523 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0348364 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.034779 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0346789 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0346513 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0346401 |
| TNRC6A | trinucleotide repeat containing 6A | 0.0343521 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | 0.0342012 |
| CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | 0.0340116 |
| JAK1 | Janus kinase 1 | 0.03394 |
| AUTS2 | autism susceptibility candidate 2 | 0.033592 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.033413 |
| MACROD2 | MACRO domain containing 2 | 0.033194 |
| PTMA | prothymosin, alpha | 0.0331817 |
| ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 | 0.0329422 |
| FAM13A | family with sequence similarity 13, member A | 0.0329388 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | 0.032745 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0325297 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.032517 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0322494 |
| MAPK8 | mitogen-activated protein kinase 8 | 0.0321853 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0320561 |
| RPS21 | ribosomal protein S21 | 0.0318728 |
| NCKAP1 | NCK-associated protein 1 | 0.0318123 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0314248 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0314226 |
| TPR | translocated promoter region, nuclear basket protein | 0.0313997 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0312121 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | 0.0311027 |
| GPHN | gephyrin | 0.0310595 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0310432 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0310054 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0309697 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | 0.0309014 |
| PGK1 | phosphoglycerate kinase 1 | 0.0305396 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0300282 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0300068 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0298109 |
| MT2A | metallothionein 2A | 0.0297626 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.0296428 |
| SEC24D | SEC24 family member D | 0.0296386 |
| PCBP2 | poly(rC) binding protein 2 | 0.0295901 |
| KIDINS220 | kinase D-interacting substrate, 220kDa | 0.0289323 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0288073 |
| WDR45B | WD repeat domain 45B | 0.0286485 |
| TPD52 | tumor protein D52 | 0.0284787 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.028392 |
| CD109 | CD109 molecule | 0.0282703 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0281033 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0279433 |
| FLNB | filamin B, beta | 0.0279427 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LMO7 | LIM domain 7 | -0.171867 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.150734 |
| MYO1E | myosin IE | -0.139516 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.126948 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.12313 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | -0.122368 |
| EXT1 | exostosin glycosyltransferase 1 | -0.11507 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0900522 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0888294 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0845379 |
| FTL | ferritin, light polypeptide | -0.0787099 |
| ANXA2 | annexin A2 | -0.078558 |
| LAMB3 | laminin, beta 3 | -0.0756853 |
| RUNX1 | runt-related transcription factor 1 | -0.0695479 |
| KRT17 | keratin 17, type I | -0.0693874 |
| SVIL | supervillin | -0.0676174 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0671766 |
| CMIP | c-Maf inducing protein | -0.0647567 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0644195 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0643919 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0635282 |
| ATOSA | atos homolog A | -0.0626293 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0619883 |
| MUC16 | mucin 16, cell surface associated | -0.0605605 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0585176 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0578036 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0576109 |
| RBM47 | RNA binding motif protein 47 | -0.0540084 |
| LAMC2 | laminin, gamma 2 | -0.0533631 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0518124 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0515179 |
| S100A9 | S100 calcium binding protein A9 | -0.049159 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0478644 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.0466342 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0460787 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0455447 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0423902 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0422196 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0416183 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0411429 |
| NHSL1 | NHS-like 1 | -0.040763 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0407367 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | -0.0400056 |
| SMOC1 | SPARC related modular calcium binding 1 | -0.0394628 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0386833 |
| WASL | Wiskott-Aldrich syndrome-like | -0.0378361 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0372717 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | -0.03653 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0364707 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | -0.0352022 |
| MYO6 | myosin VI | -0.0350849 |
| AHNAK | AHNAK nucleoprotein | -0.0347503 |
| ASPH | aspartate beta-hydroxylase | -0.0347396 |
| EPB41L5 | erythrocyte membrane protein band 4.1 like 5 | -0.0347299 |
| DSPP | dentin sialophosphoprotein | -0.0343031 |
| PLEKHA1 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 | -0.0333115 |
| STEAP4 | STEAP family member 4 | -0.0328269 |
| CATSPERB | catsper channel auxiliary subunit beta | -0.0326181 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | -0.0325327 |
| MEF2A | myocyte enhancer factor 2A | -0.0322857 |
| SNX9 | sorting nexin 9 | -0.0316382 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0315315 |
| LDHA | lactate dehydrogenase A | -0.0315263 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.031511 |
| ABHD17C | abhydrolase domain containing 17C | -0.0313234 |
| MYO5B | myosin VB | -0.0311157 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.0307764 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0307482 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0305907 |
| RESF1 | retroelement silencing factor 1 | -0.030578 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | -0.0303811 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0303181 |
| MCL1 | myeloid cell leukemia 1 | -0.0295476 |
| VIM | vimentin | -0.0294239 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0288017 |
| JUP | junction plakoglobin | -0.0286566 |
| PDS5B | PDS5 cohesin associated factor B | -0.0280294 |
| KDM7A | lysine (K)-specific demethylase 7A | -0.0279981 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0278536 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0277055 |
| FOXO1 | forkhead box O1 | -0.0277008 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0276236 |
| OCLN | occludin | -0.0276188 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0272313 |
| UBAP1 | ubiquitin associated protein 1 | -0.0271747 |
| FBXO34 | F-box protein 34 | -0.0269527 |
| TPM4 | tropomyosin 4 | -0.0269519 |
| ANXA1 | annexin A1 | -0.0269287 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0267023 |
| ATP11B | ATPase, class VI, type 11B | -0.0266171 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.026615 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0266112 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0265215 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0265031 |
| AFDN | afadin, adherens junction formation factor | -0.0264039 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | -0.0259785 |
| SDCBP2 | syndecan binding protein (syntenin) 2 | -0.0257525 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | -0.0255975 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0253033 |
| TC2N | tandem C2 domains, nuclear | -0.0252847 |
