| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Omeprazole (sodium) perturbation in NCI-H460 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Omeprazole (sodium)_NCI-H460 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GDA | guanine deaminase | 0.0935312 |
| DST | dystonin | 0.0740381 |
| EPB41L3 | erythrocyte membrane protein band 4.1-like 3 | 0.0672284 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0566808 |
| MYOF | myoferlin | 0.0523121 |
| CTSC | cathepsin C | 0.0498773 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0477289 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.046775 |
| EFNA5 | ephrin-A5 | 0.044051 |
| KYNU | kynureninase | 0.0434697 |
| NRCAM | neuronal cell adhesion molecule | 0.0421769 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0394195 |
| PDLIM5 | PDZ and LIM domain 5 | 0.036291 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0354211 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0352026 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0350714 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0319075 |
| COL8A1 | collagen, type VIII, alpha 1 | 0.031105 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.0306416 |
| PCBP3 | poly(rC) binding protein 3 | 0.0287478 |
| ASPH | aspartate beta-hydroxylase | 0.0286938 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.028651 |
| COL4A6 | collagen, type IV, alpha 6 | 0.0277028 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0275528 |
| MFF | mitochondrial fission factor | 0.0274169 |
| MT2A | metallothionein 2A | 0.0268839 |
| PM20D1 | peptidase M20 domain containing 1 | 0.0259585 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 0.0250433 |
| NEK7 | NIMA-related kinase 7 | 0.0209299 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.020747 |
| CD109 | CD109 molecule | 0.0200599 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0198985 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | 0.0192134 |
| STC2 | stanniocalcin 2 | 0.0186792 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.0184894 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0183092 |
| ATXN1 | ataxin 1 | 0.0175744 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0175123 |
| NHSL1 | NHS-like 1 | 0.0174242 |
| VCL | vinculin | 0.017282 |
| PTEN | phosphatase and tensin homolog | 0.0172277 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0166875 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0162964 |
| TNFRSF19 | tumor necrosis factor receptor superfamily, member 19 | 0.0161593 |
| FLNB | filamin B, beta | 0.0159767 |
| EPGN | epithelial mitogen | 0.0158978 |
| COL4A5 | collagen, type IV, alpha 5 | 0.0156303 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0154072 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0151576 |
| VMP1 | vacuole membrane protein 1 | 0.0150177 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.01501 |
| TGFBR1 | transforming growth factor, beta receptor 1 | 0.0147693 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0145546 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | 0.014543 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.0144154 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | 0.014336 |
| UTY | ubiquitously transcribed tetratricopeptide repeat containing, Y-linked | 0.0142825 |
| NRG1 | neuregulin 1 | 0.0142691 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0141874 |
| PRKACB | protein kinase, cAMP-dependent, catalytic, beta | 0.0135119 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0135064 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0132621 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0123759 |
| GLIS3 | GLIS family zinc finger 3 | 0.012357 |
| MALT1 | MALT1 paracaspase | 0.0123549 |
| IL1RAP | interleukin 1 receptor accessory protein | 0.0120706 |
| RAB3B | RAB3B, member RAS oncogene family | 0.0120583 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0119331 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0118479 |
| MB21D2 | Mab-21 domain containing 2 | 0.0114002 |
| DCLK2 | doublecortin-like kinase 2 | 0.0113528 |
| RTN1 | reticulon 1 | 0.0112914 |
| DNER | delta/notch-like EGF repeat containing | 0.0112398 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0111887 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0111227 |
| MT1X | metallothionein 1X | 0.0109193 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0108959 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.010845 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0108305 |
| MKI67 | marker of proliferation Ki-67 | 0.0106408 |
| FBXL5 | F-box and leucine-rich repeat protein 5 | 0.0105841 |
| GPAT3 | glycerol-3-phosphate acyltransferase 3 | 0.010357 |
| MN1 | meningioma (disrupted in balanced translocation) 1 | 0.0102985 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.0102719 |
| ZNF292 | zinc finger protein 292 | 0.0102505 |
| VPS13C | vacuolar protein sorting 13 homolog C (S. cerevisiae) | 0.0101269 |
| BDNF | brain-derived neurotrophic factor | 0.0100365 |
| ARRDC3 | arrestin domain containing 3 | 0.009886 |
| COPA | coatomer protein complex, subunit alpha | 0.00982512 |
| HSPA8 | heat shock 70kDa protein 8 | 0.00977412 |
| WDFY2 | WD repeat and FYVE domain containing 2 | 0.0096886 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.00960713 |
| PID1 | phosphotyrosine interaction domain containing 1 | 0.0095821 |
| ENAH | enabled homolog (Drosophila) | 0.00952497 |
| GLCCI1 | glucocorticoid induced 1 | 0.00947589 |
| ANKRD17 | ankyrin repeat domain 17 | 0.00947301 |
| GPC6 | glypican 6 | 0.00946719 |
| RBMS2 | RNA binding motif, single stranded interacting protein 2 | 0.0094365 |
| ZC3H12C | zinc finger CCCH-type containing 12C | 0.00943009 |
| ZBTB41 | zinc finger and BTB domain containing 41 | 0.00939596 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.152707 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.145377 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.116701 |
| PTMA | prothymosin, alpha | -0.103248 |
| TMSB10 | thymosin beta 10 | -0.0951796 |
| VIM | vimentin | -0.0862648 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0763226 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0745176 |
| RPLP1 | ribosomal protein, large, P1 | -0.0737362 |
| RPS6 | ribosomal protein S6 | -0.0688813 |
| RPS24 | ribosomal protein S24 | -0.0662127 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0640301 |
| FN1 | fibronectin 1 | -0.0608207 |
| RPL37A | ribosomal protein L37a | -0.0589241 |
| CDH13 | cadherin 13 | -0.0588933 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0581663 |
| RPL26 | ribosomal protein L26 | -0.0570483 |
| RPS8 | ribosomal protein S8 | -0.0543944 |
| RPL35A | ribosomal protein L35a | -0.0513293 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0495502 |
| RPL31 | ribosomal protein L31 | -0.0473699 |
| RPS12 | ribosomal protein S12 | -0.046489 |
| COL5A2 | collagen, type V, alpha 2 | -0.046171 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0457108 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0452418 |
| RPS19 | ribosomal protein S19 | -0.0442909 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.043891 |
| B2M | beta-2-microglobulin | -0.0437112 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.043699 |
| RPL12 | ribosomal protein L12 | -0.0421263 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0421259 |
| RPL19 | ribosomal protein L19 | -0.0415056 |
| RPL34 | ribosomal protein L34 | -0.0414913 |
| RPLP0 | ribosomal protein, large, P0 | -0.0397133 |
| RPS21 | ribosomal protein S21 | -0.0392238 |
| RPL23 | ribosomal protein L23 | -0.0391739 |
| SPAG9 | sperm associated antigen 9 | -0.0390684 |
| RPL9 | ribosomal protein L9 | -0.0380529 |
| DPP10 | dipeptidyl-peptidase 10 (non-functional) | -0.0378892 |
| RPS23 | ribosomal protein S23 | -0.036815 |
| RPS27A | ribosomal protein S27a | -0.0368147 |
| S100A6 | S100 calcium binding protein A6 | -0.0357415 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.035506 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0349726 |
| RPL36A | ribosomal protein L36a | -0.034776 |
| RPS3 | ribosomal protein S3 | -0.0341791 |
| SMYD3 | SET and MYND domain containing 3 | -0.0341695 |
| RPS14 | ribosomal protein S14 | -0.0341007 |
| RPL11 | ribosomal protein L11 | -0.0339142 |
| HLA-B | major histocompatibility complex, class I, B | -0.033861 |
| RPS25 | ribosomal protein S25 | -0.0338406 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0337206 |
| RPL37 | ribosomal protein L37 | -0.0334105 |
| RPL7A | ribosomal protein L7a | -0.0325245 |
| S100A10 | S100 calcium binding protein A10 | -0.0312997 |
| RPLP2 | ribosomal protein, large, P2 | -0.0311171 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0305608 |
| RPS16 | ribosomal protein S16 | -0.0304794 |
| RPS29 | ribosomal protein S29 | -0.0298388 |
| CANX | calnexin | -0.0297977 |
| KIAA0825 | KIAA0825 | -0.0294702 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.029375 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.029217 |
| RPS13 | ribosomal protein S13 | -0.0288402 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0287431 |
| RPL38 | ribosomal protein L38 | -0.0282706 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0282218 |
| LMNA | lamin A/C | -0.0277924 |
| ACTG1 | actin gamma 1 | -0.0274488 |
| GNAS | GNAS complex locus | -0.0266864 |
| RPL36 | ribosomal protein L36 | -0.026327 |
| RPS4X | ribosomal protein S4, X-linked | -0.0262924 |
| RPS27 | ribosomal protein S27 | -0.0261005 |
| FTL | ferritin, light polypeptide | -0.0258836 |
| LSAMP | limbic system-associated membrane protein | -0.0255245 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0254663 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0254109 |
| OASL | 2'-5'-oligoadenylate synthetase-like | -0.0253931 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | -0.0249374 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0249055 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0248193 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0244373 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0241216 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0240949 |
| RPL32 | ribosomal protein L32 | -0.0239435 |
| HLA-A | major histocompatibility complex, class I, A | -0.0239382 |
| RPS17 | ribosomal protein S17 | -0.0238201 |
| ENO1 | enolase 1, (alpha) | -0.023764 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0233949 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | -0.0233028 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0229267 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0228905 |
| YBX3 | Y box binding protein 3 | -0.0224335 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0223362 |
| RPL5 | ribosomal protein L5 | -0.0222858 |
| RPL35 | ribosomal protein L35 | -0.022184 |
| RPL13A | ribosomal protein L13a | -0.0219759 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0216307 |
| ANXA2 | annexin A2 | -0.0215852 |
| RPS11 | ribosomal protein S11 | -0.0211587 |