| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Omeprazole (sodium) perturbation in NCI-H596 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Omeprazole (sodium)_NCI-H596 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NAMPT | nicotinamide phosphoribosyltransferase | 0.13138 |
| DTNA | dystrobrevin, alpha | 0.0984178 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0964704 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0942788 |
| RLF | rearranged L-myc fusion | 0.0927405 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0793289 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0789479 |
| ELOF1 | elongation factor 1 homolog (S. cerevisiae) | 0.0788878 |
| DST | dystonin | 0.0775173 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0766637 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0749524 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0734673 |
| CTBP2 | C-terminal binding protein 2 | 0.070675 |
| HDAC9 | histone deacetylase 9 | 0.0703758 |
| ZFR | zinc finger RNA binding protein | 0.0685809 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0670264 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0667071 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.064821 |
| RNF145 | ring finger protein 145 | 0.0646876 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0635254 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0632698 |
| MYO1D | myosin ID | 0.0598554 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0587849 |
| PHF3 | PHD finger protein 3 | 0.0580786 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0579482 |
| RUNX1 | runt-related transcription factor 1 | 0.0576454 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0575373 |
| NCOR1 | nuclear receptor corepressor 1 | 0.056964 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0555158 |
| ATP11B | ATPase, class VI, type 11B | 0.0530664 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | 0.0526032 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0520537 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0520322 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.050811 |
| RPL8 | ribosomal protein L8 | 0.0501631 |
| PTK2 | protein tyrosine kinase 2 | 0.0501343 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0500827 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0496796 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0480946 |
| MT2A | metallothionein 2A | 0.0479106 |
| EFNA5 | ephrin-A5 | 0.0477533 |
| PDE10A | phosphodiesterase 10A | 0.0472843 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0466742 |
| IRS2 | insulin receptor substrate 2 | 0.0463073 |
| ZNF292 | zinc finger protein 292 | 0.0447869 |
| RPL37 | ribosomal protein L37 | 0.0427693 |
| PPP1R12B | protein phosphatase 1, regulatory subunit 12B | 0.0421762 |
| DSTN | destrin (actin depolymerizing factor) | 0.040828 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0402856 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0398825 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.0391786 |
| SFTPA2 | surfactant protein A2 | 0.0379049 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0376819 |
| JAK1 | Janus kinase 1 | 0.0363743 |
| RASAL2 | RAS protein activator like 2 | 0.0363305 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0358275 |
| EHBP1 | EH domain binding protein 1 | 0.0357412 |
| MYO1E | myosin IE | 0.0347591 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | 0.0340002 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | 0.0335956 |
| RBM39 | RNA binding motif protein 39 | 0.0330553 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.032638 |
| ETNK1 | ethanolamine kinase 1 | 0.0320566 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0314817 |
| RORA | RAR-related orphan receptor A | 0.0313664 |
| JMJD1C | jumonji domain containing 1C | 0.0306239 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0297947 |
| S100A6 | S100 calcium binding protein A6 | 0.0289794 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0284709 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.02778 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0276189 |
| H3-3B | H3.3 histone B | 0.026023 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.025364 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0249555 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0242308 |
| ACTG1 | actin gamma 1 | 0.023132 |
| S100A10 | S100 calcium binding protein A10 | 0.0230884 |
| CAMK2D | calcium/calmodulin-dependent protein kinase II delta | 0.022691 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | 0.0224156 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | 0.0215563 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0199318 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.019585 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0187972 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0179176 |
| LMO7 | LIM domain 7 | 0.0173397 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.0172264 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0147969 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0147361 |
| SPAG9 | sperm associated antigen 9 | 0.0146548 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0140394 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0138809 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.013615 |
| RAB10 | RAB10, member RAS oncogene family | 0.0129915 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0128058 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0126469 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0120253 |
| SETD5 | SET domain containing 5 | 0.0120089 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0116473 |
| RAD51B | RAD51 paralog B | 0.011626 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0113389 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.337945 |
| VIM | vimentin | -0.268181 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.152155 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.146825 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.13829 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.134754 |
| EGFR | epidermal growth factor receptor | -0.134349 |
| TMSB10 | thymosin beta 10 | -0.130485 |
| PKM | pyruvate kinase, muscle | -0.120719 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.11786 |
| STC1 | stanniocalcin 1 | -0.114586 |
| AHNAK | AHNAK nucleoprotein | -0.0971978 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0970617 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0950705 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0837491 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.079061 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0719043 |
| MAP4 | microtubule-associated protein 4 | -0.0699616 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0635022 |
| SMYD3 | SET and MYND domain containing 3 | -0.0621264 |
| LOXL2 | lysyl oxidase-like 2 | -0.0608859 |
| IGF2 | insulin-like growth factor 2 | -0.0552602 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0547111 |
| RPL11 | ribosomal protein L11 | -0.0542008 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0536579 |
| NAV1 | neuron navigator 1 | -0.0525392 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.049289 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0486014 |
| PRELID2 | PRELI domain containing 2 | -0.0474223 |
| B2M | beta-2-microglobulin | -0.0465744 |
| S100A9 | S100 calcium binding protein A9 | -0.0451967 |
| RPS16 | ribosomal protein S16 | -0.0451011 |
| FMNL2 | formin-like 2 | -0.044409 |
| RACK1 | receptor for activated C kinase 1 | -0.0430707 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0428892 |
| ITGA6 | integrin, alpha 6 | -0.0427172 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0422174 |
| HLA-B | major histocompatibility complex, class I, B | -0.0413027 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0411255 |
| PTMA | prothymosin, alpha | -0.0410269 |
| CD44 | CD44 molecule (Indian blood group) | -0.0407918 |
| ANXA2 | annexin A2 | -0.0406619 |
| FN1 | fibronectin 1 | -0.0404311 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0401743 |
| ASPH | aspartate beta-hydroxylase | -0.0401144 |
| SNX14 | sorting nexin 14 | -0.03991 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0383729 |
| CCNI | cyclin I | -0.037804 |
| ANO6 | anoctamin 6 | -0.0341005 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0324248 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0322007 |
| TXNRD1 | thioredoxin reductase 1 | -0.0313141 |
| RPL13A | ribosomal protein L13a | -0.0311221 |
| ERCC6L2 | excision repair cross-complementation group 6-like 2 | -0.0310118 |
| TOR1AIP2 | torsin A interacting protein 2 | -0.0302683 |
| RNF213 | ring finger protein 213 | -0.0283607 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0282136 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0274793 |
| SEC62 | SEC62 homolog (S. cerevisiae) | -0.0262433 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0253 |
| OSMR | oncostatin M receptor | -0.0247535 |
| EXOC6B | exocyst complex component 6B | -0.0242781 |
| MYOF | myoferlin | -0.0239899 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0239371 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0237098 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.0233916 |
| GPC6 | glypican 6 | -0.0231864 |
| COL5A2 | collagen, type V, alpha 2 | -0.0230671 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0222995 |
| NF1 | neurofibromin 1 | -0.022019 |
| RPS8 | ribosomal protein S8 | -0.0219678 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0214353 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0202 |
| FOXP1 | forkhead box P1 | -0.0201028 |
| INTS6 | integrator complex subunit 6 | -0.0198462 |
| TRIP12 | thyroid hormone receptor interactor 12 | -0.0191518 |
| USP34 | ubiquitin specific peptidase 34 | -0.0186649 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.018452 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0183196 |
| LDHA | lactate dehydrogenase A | -0.0181066 |
| CARD16 | caspase recruitment domain family, member 16 | -0.017999 |
| MAP1B | microtubule-associated protein 1B | -0.0170647 |
| SP100 | SP100 nuclear antigen | -0.0169004 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | -0.0157394 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0156573 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0154522 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0154418 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0148953 |
| TAOK3 | TAO kinase 3 | -0.0143605 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0138644 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0132614 |
| RPLP1 | ribosomal protein, large, P1 | -0.0114203 |
| PRKCA | protein kinase C, alpha | -0.0110249 |
| KCTD9 | potassium channel tetramerization domain containing 9 | -0.0102531 |
| CNKSR3 | CNKSR family member 3 | -0.00903159 |
| NFIA | nuclear factor I/A | -0.00688131 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | -0.00675599 |
| FAM13A | family with sequence similarity 13, member A | -0.00595144 |
| POTEF | POTE ankyrin domain family, member F | -0.00544266 |
| TENM3 | teneurin transmembrane protein 3 | -0.00536232 |
