| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Omeprazole (sodium) perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Omeprazole (sodium)_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TRPS1 | trichorhinophalangeal syndrome I | 0.0903531 |
| COL11A1 | collagen, type XI, alpha 1 | 0.0853855 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0794302 |
| HDAC9 | histone deacetylase 9 | 0.0718923 |
| PEG10 | paternally expressed 10 | 0.0709113 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0630257 |
| CDC73 | cell division cycle 73 | 0.0609558 |
| ADGRV1 | adhesion G protein-coupled receptor V1 | 0.0583509 |
| NCKAP1 | NCK-associated protein 1 | 0.0579321 |
| DST | dystonin | 0.054781 |
| EMP1 | epithelial membrane protein 1 | 0.0540081 |
| PRKD1 | protein kinase D1 | 0.0532527 |
| SEMA3D | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D | 0.0522919 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0507265 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0501781 |
| ZNF292 | zinc finger protein 292 | 0.0490774 |
| SPAG9 | sperm associated antigen 9 | 0.0488179 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0483549 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0482634 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0477806 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.0468304 |
| SHROOM3 | shroom family member 3 | 0.0461728 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0437359 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0434611 |
| PGAP1 | post-GPI attachment to proteins 1 | 0.0427836 |
| USP3 | ubiquitin specific peptidase 3 | 0.0421686 |
| GALNTL6 | polypeptide N-acetylgalactosaminyltransferase-like 6 | 0.0418882 |
| FIGN | fidgetin | 0.0411314 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0408468 |
| RHEB | Ras homolog enriched in brain | 0.0404913 |
| MTF2 | metal response element binding transcription factor 2 | 0.0403865 |
| CTNNA3 | catenin (cadherin-associated protein), alpha 3 | 0.0402515 |
| NCOR1 | nuclear receptor corepressor 1 | 0.0394588 |
| SRP54 | signal recognition particle 54kDa | 0.037416 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0357982 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.0355428 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0354941 |
| JMJD1C | jumonji domain containing 1C | 0.0349406 |
| MB21D2 | Mab-21 domain containing 2 | 0.0346736 |
| ZNF217 | zinc finger protein 217 | 0.0346321 |
| DENND4C | DENN/MADD domain containing 4C | 0.0343756 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0343122 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0339385 |
| ACTN4 | actinin, alpha 4 | 0.0338933 |
| ADGRL3 | adhesion G protein-coupled receptor L3 | 0.0338786 |
| CADM2 | cell adhesion molecule 2 | 0.0337464 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0332969 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0332595 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0330948 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0329924 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.032918 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0328632 |
| APP | amyloid beta (A4) precursor protein | 0.0328588 |
| ENAH | enabled homolog (Drosophila) | 0.0325201 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0324514 |
| SMG7 | SMG7 nonsense mediated mRNA decay factor | 0.0321303 |
| PSMA6 | proteasome (prosome, macropain) subunit, alpha type, 6 | 0.0314513 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.03125 |
| HYCC2 | hyccin PI4KA lipid kinase complex subunit 2 | 0.0308207 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0306822 |
| CELF2 | CUGBP, Elav-like family member 2 | 0.0302824 |
| HELZ | helicase with zinc finger | 0.0300308 |
| PPP4R1 | protein phosphatase 4, regulatory subunit 1 | 0.0298511 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | 0.0295338 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | 0.0292297 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | 0.0290075 |
| MITF | microphthalmia-associated transcription factor | 0.0285033 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0282428 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | 0.0280666 |
| TRIM33 | tripartite motif containing 33 | 0.0280547 |
| RAD51B | RAD51 paralog B | 0.02776 |
| WWC2 | WW and C2 domain containing 2 | 0.027653 |
| RTTN | rotatin | 0.0276168 |
| UBAP2L | ubiquitin associated protein 2-like | 0.0274707 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.027174 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0270896 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.0269684 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0269357 |
| PRPF8 | pre-mRNA processing factor 8 | 0.0268531 |
| SERINC1 | serine incorporator 1 | 0.026748 |
| SBNO1 | strawberry notch homolog 1 (Drosophila) | 0.0265398 |
| MIER1 | mesoderm induction early response 1, transcriptional regulator | 0.0265243 |
| RASAL2 | RAS protein activator like 2 | 0.0264943 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.026406 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0263823 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | 0.0261008 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0259409 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0258097 |
| MEF2A | myocyte enhancer factor 2A | 0.0254166 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | 0.0253839 |
| ELOVL5 | ELOVL fatty acid elongase 5 | 0.0253587 |
| CLTC | clathrin, heavy chain (Hc) | 0.0251544 |
| TMEM39A | transmembrane protein 39A | 0.025117 |
| MEIS2 | Meis homeobox 2 | 0.0250727 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0249411 |
| NCOA3 | nuclear receptor coactivator 3 | 0.0248109 |
| CALCR | calcitonin receptor | 0.0246892 |
| MATR3 | matrin 3 | 0.0245561 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0243889 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | 0.0241035 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.179903 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0959819 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0946598 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0802454 |
| RPS16 | ribosomal protein S16 | -0.0796135 |
| TMSB10 | thymosin beta 10 | -0.0791438 |
| ACTG1 | actin gamma 1 | -0.0638977 |
| SYT1 | synaptotagmin I | -0.0623963 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0617397 |
| RPLP1 | ribosomal protein, large, P1 | -0.0601858 |
| RPS8 | ribosomal protein S8 | -0.0574428 |
| TENM3 | teneurin transmembrane protein 3 | -0.0573983 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0562537 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | -0.0546197 |
| COL5A2 | collagen, type V, alpha 2 | -0.0505603 |
| COL3A1 | collagen, type III, alpha 1 | -0.0500341 |
| ENO1 | enolase 1, (alpha) | -0.0490483 |
| PCDH7 | protocadherin 7 | -0.0464249 |
| RPS19 | ribosomal protein S19 | -0.0460801 |
| RPS13 | ribosomal protein S13 | -0.0458528 |
| HMGB1 | high mobility group box 1 | -0.04585 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0457731 |
| RPL31 | ribosomal protein L31 | -0.044601 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.0437866 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0422172 |
| CCN2 | cellular communication network factor 2 | -0.0418104 |
| RPL23 | ribosomal protein L23 | -0.0417059 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0407163 |
| NRG1 | neuregulin 1 | -0.0403641 |
| RPL37 | ribosomal protein L37 | -0.040203 |
| RPS6 | ribosomal protein S6 | -0.0398455 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0389664 |
| RPS24 | ribosomal protein S24 | -0.0385083 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0381309 |
| RPL35A | ribosomal protein L35a | -0.0379075 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0376202 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0374764 |
| NSUN6 | NOP2/Sun domain family, member 6 | -0.0374426 |
| CDK6 | cyclin-dependent kinase 6 | -0.0373997 |
| PGK1 | phosphoglycerate kinase 1 | -0.0373034 |
| TCEA1 | transcription elongation factor A (SII), 1 | -0.037115 |
| CDH19 | cadherin 19, type 2 | -0.0367624 |
| RPS12 | ribosomal protein S12 | -0.0361576 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0359963 |
| TEX11 | testis expressed 11 | -0.0355664 |
| SNX6 | sorting nexin 6 | -0.0353055 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0345198 |
| RPL19 | ribosomal protein L19 | -0.0344478 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0342402 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0336305 |
| ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 | -0.0332827 |
| MKI67 | marker of proliferation Ki-67 | -0.0328773 |
| RPL11 | ribosomal protein L11 | -0.0324397 |
| DEK | DEK proto-oncogene | -0.0323826 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0322258 |
| LHFPL6 | LHFPL tetraspan subfamily member 6 | -0.0320144 |
| RPL37A | ribosomal protein L37a | -0.0318694 |
| TMSB4X | thymosin beta 4, X-linked | -0.0316379 |
| EXOC4 | exocyst complex component 4 | -0.0310493 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0309631 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.0306505 |
| RPLP0 | ribosomal protein, large, P0 | -0.0300557 |
| RPLP2 | ribosomal protein, large, P2 | -0.0299931 |
| ARHGAP15 | Rho GTPase activating protein 15 | -0.0295969 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.029399 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.029034 |
| S100A9 | S100 calcium binding protein A9 | -0.0287432 |
| PCDH9 | protocadherin 9 | -0.0285245 |
| SNAPC1 | small nuclear RNA activating complex, polypeptide 1, 43kDa | -0.0284804 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0282585 |
| RPL34 | ribosomal protein L34 | -0.0282268 |
| SET | SET nuclear proto-oncogene | -0.0280636 |
| RPS4X | ribosomal protein S4, X-linked | -0.0280321 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0278074 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.0278052 |
| PFN1 | profilin 1 | -0.0278004 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0276958 |
| RPS15 | ribosomal protein S15 | -0.0276483 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | -0.0276373 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0273313 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0270901 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.0270824 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.027 |
| RPL30 | ribosomal protein L30 | -0.0267703 |
| CKAP2 | cytoskeleton associated protein 2 | -0.0266051 |
| MED13L | mediator complex subunit 13-like | -0.0264753 |
| KIAA1328 | KIAA1328 | -0.0262161 |
| RPL9 | ribosomal protein L9 | -0.0261197 |
| USP34 | ubiquitin specific peptidase 34 | -0.0261164 |
| RPL7 | ribosomal protein L7 | -0.0259889 |
| ITSN1 | intersectin 1 (SH3 domain protein) | -0.0259799 |
| RAI1 | retinoic acid induced 1 | -0.0259133 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0258809 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | -0.0258465 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0258308 |
| GLI3 | GLI family zinc finger 3 | -0.0257695 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0255873 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0255676 |
| TUBA1B | tubulin, alpha 1b | -0.0255257 |
| EIF3K | eukaryotic translation initiation factor 3, subunit K | -0.0253867 |
