| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Omeprazole (sodium) perturbation in PANC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Omeprazole (sodium)_PANC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0560983 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0409713 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0383462 |
| VCL | vinculin | 0.033691 |
| ZFP36 | ZFP36 ring finger protein | 0.0334036 |
| TMEM41B | transmembrane protein 41B | 0.0325938 |
| ACTN4 | actinin, alpha 4 | 0.0313496 |
| RTN4 | reticulon 4 | 0.026895 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0268562 |
| GCNT2 | glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) | 0.0260502 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.0253064 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0246123 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.024202 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0240932 |
| PLEKHG2 | pleckstrin homology domain containing, family G (with RhoGef domain) member 2 | 0.023216 |
| TXNRD1 | thioredoxin reductase 1 | 0.0222325 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0218048 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0209417 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0207793 |
| FOSL1 | FOS-like antigen 1 | 0.0198904 |
| VMP1 | vacuole membrane protein 1 | 0.017739 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0177114 |
| FHL2 | four and a half LIM domains 2 | 0.017352 |
| ARRDC3 | arrestin domain containing 3 | 0.0170954 |
| ATP13A3 | ATPase type 13A3 | 0.0170049 |
| ITGAV | integrin, alpha V | 0.0159094 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0154827 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0152412 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0143011 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0128575 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0125488 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.012396 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0122474 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | 0.0120704 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0116809 |
| CD44 | CD44 molecule (Indian blood group) | 0.0116125 |
| SFTPA2 | surfactant protein A2 | 0.0115064 |
| JMJD1C | jumonji domain containing 1C | 0.0114902 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0113696 |
| ITGB5 | integrin, beta 5 | 0.0113492 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0111152 |
| NPC1 | Niemann-Pick disease, type C1 | 0.0110054 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0109643 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0106328 |
| BMP6 | bone morphogenetic protein 6 | 0.0103853 |
| KLF6 | Kruppel-like factor 6 | 0.0103643 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.0101153 |
| PGK1 | phosphoglycerate kinase 1 | 0.0100137 |
| SEPTIN10 | septin 10 | 0.00995009 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.00989572 |
| SNX14 | sorting nexin 14 | 0.00988101 |
| ICAM1 | intercellular adhesion molecule 1 | 0.00986223 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.00974032 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.00972752 |
| NUP58 | nucleoporin 58 | 0.00943777 |
| SPRY4 | sprouty homolog 4 (Drosophila) | 0.00917616 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.00914152 |
| SLC38A2 | solute carrier family 38, member 2 | 0.00894713 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.00879451 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.00868371 |
| ANLN | anillin, actin binding protein | 0.00841396 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.00833831 |
| RNF145 | ring finger protein 145 | 0.00824105 |
| AMN1 | antagonist of mitotic exit network 1 homolog (S. cerevisiae) | 0.00823984 |
| MSMO1 | methylsterol monooxygenase 1 | 0.00819899 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.00812013 |
| SEC14L1 | SEC14-like 1 (S. cerevisiae) | 0.00811071 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 0.00810166 |
| CD59 | CD59 molecule, complement regulatory protein | 0.00805128 |
| CTTNBP2NL | CTTNBP2 N-terminal like | 0.00802638 |
| ELOVL5 | ELOVL fatty acid elongase 5 | 0.00795613 |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.00774477 |
| NEK7 | NIMA-related kinase 7 | 0.00763377 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.00762024 |
| FOXJ3 | forkhead box J3 | 0.00754566 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.00753801 |
| WEE1 | WEE1 G2 checkpoint kinase | 0.00750155 |
| UBC | ubiquitin C | 0.00748964 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0074888 |
| FAM3C | family with sequence similarity 3, member C | 0.00745584 |
| ZNF292 | zinc finger protein 292 | 0.00744733 |
| FRMD6 | FERM domain containing 6 | 0.00742828 |
| EGR1 | early growth response 1 | 0.00741136 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.00731862 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.00728692 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.00720477 |
| C1ORF52 | chromosome 1 open reading frame 52 | 0.00719497 |
| ANXA2 | annexin A2 | 0.00716057 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.00706299 |
| DNMBP | dynamin binding protein | 0.00703971 |
| TXNDC12 | thioredoxin domain containing 12 (endoplasmic reticulum) | 0.00701784 |
| USP12 | ubiquitin specific peptidase 12 | 0.00693995 |
| DSTN | destrin (actin depolymerizing factor) | 0.006849 |
| F2RL1 | coagulation factor II (thrombin) receptor-like 1 | 0.00682385 |
| CDCP1 | CUB domain containing protein 1 | 0.00677599 |
| TMEM123 | transmembrane protein 123 | 0.00673167 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.00672844 |
| LDLR | low density lipoprotein receptor | 0.00671466 |
| CCNL1 | cyclin L1 | 0.006693 |
| FDPS | farnesyl diphosphate synthase | 0.00657027 |
| Symbol | Name | Standardized Value |
|---|---|---|
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.11652 |
| RPS16 | ribosomal protein S16 | -0.101864 |
| AHNAK | AHNAK nucleoprotein | -0.08352 |
| VIM | vimentin | -0.0735891 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.069331 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0686959 |
| PTMA | prothymosin, alpha | -0.0590105 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0576468 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0520027 |
| SLC35F3 | solute carrier family 35, member F3 | -0.051332 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0416276 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0397038 |
| PTK2 | protein tyrosine kinase 2 | -0.0394193 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0375381 |
| TNS3 | tensin 3 | -0.0360731 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0360444 |
| DST | dystonin | -0.0338074 |
| FBL | fibrillarin | -0.0335605 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.0329777 |
| TMSB10 | thymosin beta 10 | -0.0310949 |
| NAV2 | neuron navigator 2 | -0.0310898 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0308939 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0294605 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0293792 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0286948 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0283552 |
| CTBP2 | C-terminal binding protein 2 | -0.0267647 |
| HMGA2 | high mobility group AT-hook 2 | -0.0260022 |
| CANX | calnexin | -0.0259328 |
| RPL35A | ribosomal protein L35a | -0.0258444 |
| RNF220 | ring finger protein 220 | -0.0248735 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0246519 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | -0.0240957 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0238429 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0236926 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0231491 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | -0.0228867 |
| ATG7 | autophagy related 7 | -0.0228429 |
| RPS24 | ribosomal protein S24 | -0.0224803 |
| RPLP2 | ribosomal protein, large, P2 | -0.022128 |
| DIAPH2 | diaphanous-related formin 2 | -0.0218785 |
| RPLP1 | ribosomal protein, large, P1 | -0.0218772 |
| EXOC4 | exocyst complex component 4 | -0.0216261 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0213191 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0213026 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0207236 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.020693 |
| MYOF | myoferlin | -0.020409 |
| CUX1 | cut-like homeobox 1 | -0.0203831 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0203784 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.020311 |
| INTS6 | integrator complex subunit 6 | -0.019921 |
| PKM | pyruvate kinase, muscle | -0.0198895 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0197384 |
| COL18A1 | collagen, type XVIII, alpha 1 | -0.0191226 |
| ENO1 | enolase 1, (alpha) | -0.0190935 |
| NHSL1 | NHS-like 1 | -0.0190147 |
| EHBP1 | EH domain binding protein 1 | -0.0187316 |
| SEPTIN9 | septin 9 | -0.0186117 |
| RAD51B | RAD51 paralog B | -0.0181414 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0180887 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0180764 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | -0.0178912 |
| MORF4L2 | mortality factor 4 like 2 | -0.0174321 |
| DOCK1 | dedicator of cytokinesis 1 | -0.0171371 |
| CTSD | cathepsin D | -0.0171233 |
| TCF12 | transcription factor 12 | -0.0170728 |
| ZNF407 | zinc finger protein 407 | -0.0170539 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0169571 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0165691 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0163102 |
| RPS8 | ribosomal protein S8 | -0.016309 |
| PRKCA | protein kinase C, alpha | -0.0160753 |
| MYO10 | myosin X | -0.0158438 |
| GOLGB1 | golgin B1 | -0.0157286 |
| CMIP | c-Maf inducing protein | -0.0153439 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | -0.0153419 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0153042 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0150984 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.0150676 |
| RNF213 | ring finger protein 213 | -0.015058 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0148202 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | -0.0148104 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0147169 |
| PRSS23 | protease, serine, 23 | -0.014606 |
| RPL37A | ribosomal protein L37a | -0.0145976 |
| AKT2 | v-akt murine thymoma viral oncogene homolog 2 | -0.0145684 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0145088 |
| RPS12 | ribosomal protein S12 | -0.0144237 |
| HM13 | histocompatibility (minor) 13 | -0.0142742 |
| SBF2 | SET binding factor 2 | -0.01427 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0142517 |
| EGFR | epidermal growth factor receptor | -0.0142357 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.0140997 |
| TIAM2 | T-cell lymphoma invasion and metastasis 2 | -0.0139406 |
| AFAP1 | actin filament associated protein 1 | -0.0138564 |
| NF1 | neurofibromin 1 | -0.0138367 |
| RASAL2 | RAS protein activator like 2 | -0.0136664 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0136087 |
| PSMC4 | proteasome (prosome, macropain) 26S subunit, ATPase, 4 | -0.0135272 |
