| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Omeprazole (sodium) perturbation in RKO cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Omeprazole (sodium)_RKO drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DLC1 | DLC1 Rho GTPase activating protein | 0.0456394 |
| TTR | transthyretin | 0.027494 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0261966 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0186633 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0178975 |
| SETD5 | SET domain containing 5 | 0.0170919 |
| ZNF292 | zinc finger protein 292 | 0.0158875 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0145157 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0134994 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0134159 |
| PIAS2 | protein inhibitor of activated STAT, 2 | 0.0131988 |
| WDR43 | WD repeat domain 43 | 0.013196 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0129442 |
| NUP58 | nucleoporin 58 | 0.0127211 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | 0.0122808 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0121917 |
| FOXJ3 | forkhead box J3 | 0.0119094 |
| FMNL2 | formin-like 2 | 0.0106801 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0106493 |
| NCKAP1 | NCK-associated protein 1 | 0.0105407 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0104858 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0104605 |
| KDM7A | lysine (K)-specific demethylase 7A | 0.0102062 |
| C1ORF52 | chromosome 1 open reading frame 52 | 0.0100185 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.00983293 |
| FRMD4A | FERM domain containing 4A | 0.00977809 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.00965196 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.00956423 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.00955426 |
| RAD51B | RAD51 paralog B | 0.00941168 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.00916589 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.00902126 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0085776 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.00856533 |
| PAPOLA | poly(A) polymerase alpha | 0.00851119 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | 0.00850536 |
| ATP13A3 | ATPase type 13A3 | 0.00825087 |
| SEC24A | SEC24 family member A | 0.00821245 |
| RNF145 | ring finger protein 145 | 0.00807267 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.00781161 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 0.00771002 |
| MXI1 | MAX interactor 1, dimerization protein | 0.00767758 |
| BBX | bobby sox homolog (Drosophila) | 0.00767291 |
| CALD1 | caldesmon 1 | 0.00763332 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 | 0.00751325 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.00743221 |
| FOXO3 | forkhead box O3 | 0.00735847 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.00734512 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0073053 |
| SBF2 | SET binding factor 2 | 0.0072713 |
| RLF | rearranged L-myc fusion | 0.00722132 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.00719888 |
| USP3 | ubiquitin specific peptidase 3 | 0.00718307 |
| TPD52 | tumor protein D52 | 0.0071036 |
| CRACD | capping protein inhibiting regulator of actin dynamics | 0.00701548 |
| MKI67 | marker of proliferation Ki-67 | 0.00694305 |
| GOLGA4 | golgin A4 | 0.00685806 |
| MTMR3 | myotubularin related protein 3 | 0.00681652 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.00679286 |
| KMT2A | lysine (K)-specific methyltransferase 2A | 0.00660419 |
| FNIP1 | folliculin interacting protein 1 | 0.00657984 |
| CAPRIN1 | cell cycle associated protein 1 | 0.0065709 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0065565 |
| CRKL | v-crk avian sarcoma virus CT10 oncogene homolog-like | 0.0065054 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.00650203 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.00650086 |
| ATN1 | atrophin 1 | 0.00646306 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | 0.00645773 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.00637262 |
| RASA2 | RAS p21 protein activator 2 | 0.00636521 |
| TET2 | tet methylcytosine dioxygenase 2 | 0.00635287 |
| SFTPA2 | surfactant protein A2 | 0.00633683 |
| PPP1R3B | protein phosphatase 1, regulatory subunit 3B | 0.00632178 |
| UBQLN1 | ubiquilin 1 | 0.00626077 |
| RAB18 | RAB18, member RAS oncogene family | 0.00625769 |
| NSD3 | nuclear receptor binding SET domain protein 3 | 0.0062567 |
| CCNL1 | cyclin L1 | 0.00620321 |
| SRPK1 | SRSF protein kinase 1 | 0.00620022 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.00618064 |
| RIC1 | RAB6A GEF complex partner 1 | 0.00617354 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.00616498 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | 0.00616312 |
| FNDC3B | fibronectin type III domain containing 3B | 0.00615437 |
| POU2F1 | POU class 2 homeobox 1 | 0.00613286 |
| HELZ | helicase with zinc finger | 0.00611061 |
| PAWR | PRKC, apoptosis, WT1, regulator | 0.00607836 |
| ANO6 | anoctamin 6 | 0.00602387 |
| TRIM33 | tripartite motif containing 33 | 0.00600788 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.00600082 |
| MEMO1 | mediator of cell motility 1 | 0.00596761 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.00591862 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | 0.00591636 |
| CKAP5 | cytoskeleton associated protein 5 | 0.00591031 |
| PDS5B | PDS5 cohesin associated factor B | 0.00589854 |
| CENPF | centromere protein F, 350/400kDa | 0.00586978 |
| YEATS2 | YEATS domain containing 2 | 0.00585106 |
| MED15 | mediator complex subunit 15 | 0.00584634 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.00582337 |
| SFXN1 | sideroflexin 1 | 0.00580786 |
| NCOR1 | nuclear receptor corepressor 1 | 0.00580613 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.104569 |
| MT2A | metallothionein 2A | -0.0880051 |
| UBC | ubiquitin C | -0.0745874 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0657424 |
| AHNAK | AHNAK nucleoprotein | -0.0632065 |
| RPS27A | ribosomal protein S27a | -0.0556401 |
| RPL23 | ribosomal protein L23 | -0.0555265 |
| ACTG1 | actin gamma 1 | -0.0552461 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0537408 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0511142 |
| ENO1 | enolase 1, (alpha) | -0.0510729 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0501231 |
| TMSB10 | thymosin beta 10 | -0.0481604 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0475447 |
| RPLP1 | ribosomal protein, large, P1 | -0.0473559 |
| EXT1 | exostosin glycosyltransferase 1 | -0.046778 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0453664 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0447767 |
| RPS6 | ribosomal protein S6 | -0.0437717 |
| JUN | jun proto-oncogene | -0.0431394 |
| RPL7A | ribosomal protein L7a | -0.0424615 |
| RPS8 | ribosomal protein S8 | -0.0402758 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0368897 |
| RPL12 | ribosomal protein L12 | -0.0367534 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0363496 |
| RPS3 | ribosomal protein S3 | -0.035938 |
| MCL1 | myeloid cell leukemia 1 | -0.0357672 |
| RPL37A | ribosomal protein L37a | -0.0355164 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.034996 |
| RPS24 | ribosomal protein S24 | -0.0347041 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0346894 |
| RPS12 | ribosomal protein S12 | -0.0342927 |
| RPLP2 | ribosomal protein, large, P2 | -0.0341189 |
| RPL9 | ribosomal protein L9 | -0.0338122 |
| RPL30 | ribosomal protein L30 | -0.0336161 |
| RPL8 | ribosomal protein L8 | -0.0335707 |
| RPL35A | ribosomal protein L35a | -0.0328008 |
| RPL7 | ribosomal protein L7 | -0.0326824 |
| RPS19 | ribosomal protein S19 | -0.0325099 |
| PKM | pyruvate kinase, muscle | -0.0322985 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0319804 |
| PTMA | prothymosin, alpha | -0.0319221 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0308353 |
| RPS21 | ribosomal protein S21 | -0.0307319 |
| SET | SET nuclear proto-oncogene | -0.0307258 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0294815 |
| RPL26 | ribosomal protein L26 | -0.0293733 |
| ARHGAP22 | Rho GTPase activating protein 22 | -0.0283798 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0283547 |
| LAMB3 | laminin, beta 3 | -0.0276631 |
| TPM4 | tropomyosin 4 | -0.0275492 |
| PCBP2 | poly(rC) binding protein 2 | -0.0270013 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0263915 |
| RPL19 | ribosomal protein L19 | -0.0256451 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0245934 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0245623 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0235363 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | -0.0231785 |
| RPL35 | ribosomal protein L35 | -0.0231043 |
| RPS29 | ribosomal protein S29 | -0.0230557 |
| PRRC2B | proline-rich coiled-coil 2B | -0.0229589 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0229236 |
| RPS13 | ribosomal protein S13 | -0.0228941 |
| RPL34 | ribosomal protein L34 | -0.0228031 |
| RPL31 | ribosomal protein L31 | -0.0226253 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0219307 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0211157 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | -0.0210006 |
| G0S2 | G0/G1 switch 2 | -0.0206977 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0206954 |
| RPS4X | ribosomal protein S4, X-linked | -0.0201451 |
| TOP1 | topoisomerase (DNA) I | -0.0201016 |
| RPS11 | ribosomal protein S11 | -0.0200111 |
| S100A6 | S100 calcium binding protein A6 | -0.0199689 |
| RPS25 | ribosomal protein S25 | -0.0198342 |
| RBM25 | RNA binding motif protein 25 | -0.0197946 |
| RPL5 | ribosomal protein L5 | -0.0197931 |
| FTL | ferritin, light polypeptide | -0.019607 |
| RPS23 | ribosomal protein S23 | -0.0196049 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0195907 |
| RPL32 | ribosomal protein L32 | -0.0194287 |
| RPS16 | ribosomal protein S16 | -0.0193786 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0193205 |
| SFPQ | splicing factor proline/glutamine-rich | -0.0192966 |
| RPL28 | ribosomal protein L28 | -0.0191163 |
| POTEF | POTE ankyrin domain family, member F | -0.0190993 |
| UPP1 | uridine phosphorylase 1 | -0.0190446 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.01897 |
| RPS15 | ribosomal protein S15 | -0.0189049 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | -0.0188052 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | -0.0187631 |
| RPS17 | ribosomal protein S17 | -0.0182768 |
| MTDH | metadherin | -0.0182412 |
| RPL11 | ribosomal protein L11 | -0.0181697 |
| RPLP0 | ribosomal protein, large, P0 | -0.0181389 |
| RPL36A | ribosomal protein L36a | -0.0180798 |
| EEF1D | eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) | -0.0179955 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0178789 |
| RPS5 | ribosomal protein S5 | -0.0175908 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0173348 |
