| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Omeprazole (sodium) perturbation in RPMI-7951 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Omeprazole (sodium)_RPMI-7951 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.108906 |
| VEGFA | vascular endothelial growth factor A | 0.0785693 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0695141 |
| NDRG1 | N-myc downstream regulated 1 | 0.0590901 |
| MT2A | metallothionein 2A | 0.0568622 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0546977 |
| MSN | moesin | 0.0507782 |
| TGM2 | transglutaminase 2 | 0.0428831 |
| CD109 | CD109 molecule | 0.0426312 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0423133 |
| POTEF | POTE ankyrin domain family, member F | 0.0383203 |
| FOSL1 | FOS-like antigen 1 | 0.0359774 |
| FAM13A | family with sequence similarity 13, member A | 0.0358207 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0351944 |
| CDCP1 | CUB domain containing protein 1 | 0.0332427 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0327652 |
| MEF2A | myocyte enhancer factor 2A | 0.0322634 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.0309658 |
| MMP12 | matrix metallopeptidase 12 | 0.0305443 |
| YEATS2 | YEATS domain containing 2 | 0.0297889 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0296581 |
| ARRDC3 | arrestin domain containing 3 | 0.0286197 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0282525 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0277473 |
| CENPF | centromere protein F, 350/400kDa | 0.027547 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0259374 |
| TMF1 | TATA element modulatory factor 1 | 0.0257597 |
| RAD51B | RAD51 paralog B | 0.0255666 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0249038 |
| NGLY1 | N-glycanase 1 | 0.0239647 |
| CDK19 | cyclin-dependent kinase 19 | 0.0238723 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0234184 |
| ANGPTL4 | angiopoietin-like 4 | 0.0226765 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.022618 |
| ZNF292 | zinc finger protein 292 | 0.0224276 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0221673 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0221571 |
| MKI67 | marker of proliferation Ki-67 | 0.021591 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0215361 |
| INSIG2 | insulin induced gene 2 | 0.0211156 |
| XPO1 | exportin 1 | 0.0210438 |
| FLNB | filamin B, beta | 0.0209687 |
| NUP58 | nucleoporin 58 | 0.0205461 |
| PFKP | phosphofructokinase, platelet | 0.0204288 |
| L1CAM | L1 cell adhesion molecule | 0.0203932 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0197962 |
| AXL | AXL receptor tyrosine kinase | 0.019649 |
| C1D | C1D nuclear receptor corepressor | 0.0189714 |
| OPTN | optineurin | 0.0189594 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0187434 |
| PLOD1 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 | 0.0186427 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0186213 |
| INSIG1 | insulin induced gene 1 | 0.0185545 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0183699 |
| MMP2 | matrix metallopeptidase 2 | 0.0182484 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0177627 |
| HDAC9 | histone deacetylase 9 | 0.0177373 |
| CD163L1 | CD163 molecule-like 1 | 0.0174678 |
| ITGB5 | integrin, beta 5 | 0.0168949 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0168399 |
| RELA | v-rel avian reticuloendotheliosis viral oncogene homolog A | 0.0167933 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0166062 |
| ZNF148 | zinc finger protein 148 | 0.0164036 |
| PLIN2 | perilipin 2 | 0.0163189 |
| MTSS1 | metastasis suppressor 1 | 0.0162463 |
| PLP2 | proteolipid protein 2 (colonic epithelium-enriched) | 0.0161508 |
| MYO1B | myosin IB | 0.0161431 |
| TPM1 | tropomyosin 1 (alpha) | 0.0158977 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0158744 |
| CCDC88A | coiled-coil domain containing 88A | 0.0157414 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.0156637 |
| CBX3 | chromobox homolog 3 | 0.0155019 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0154226 |
| SKAP2 | src kinase associated phosphoprotein 2 | 0.0151068 |
| CEP192 | centrosomal protein 192kDa | 0.0146456 |
| DEPP1 | DEPP autophagy regulator 1 | 0.0145407 |
| SNAPC3 | small nuclear RNA activating complex, polypeptide 3, 50kDa | 0.0145403 |
| FBXL5 | F-box and leucine-rich repeat protein 5 | 0.0144118 |
| THBS1 | thrombospondin 1 | 0.0144009 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.0143445 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0143182 |
| CYB5R3 | cytochrome b5 reductase 3 | 0.0141987 |
| ZNF160 | zinc finger protein 160 | 0.0137873 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0135256 |
| ZNF395 | zinc finger protein 395 | 0.0134814 |
| NCKAP1 | NCK-associated protein 1 | 0.013307 |
| COLEC10 | collectin sub-family member 10 (C-type lectin) | 0.0132533 |
| CALD1 | caldesmon 1 | 0.0132288 |
| CEP152 | centrosomal protein 152kDa | 0.0132154 |
| ABHD2 | abhydrolase domain containing 2 | 0.0131938 |
| CA12 | carbonic anhydrase XII | 0.0131933 |
| CDON | cell adhesion associated, oncogene regulated | 0.0131359 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0130612 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0130347 |
| PKM | pyruvate kinase, muscle | 0.0128737 |
| FAM162A | family with sequence similarity 162, member A | 0.0127748 |
| ARHGAP11A | Rho GTPase activating protein 11A | 0.0127653 |
| MIGA1 | mitoguardin 1 | 0.0127593 |
| USP37 | ubiquitin specific peptidase 37 | 0.0126787 |
| RPL3 | ribosomal protein L3 | 0.0126466 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.201373 |
| VIM | vimentin | -0.15578 |
| CD44 | CD44 molecule (Indian blood group) | -0.101416 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0933941 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.088002 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0791904 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0691109 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0639696 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0605155 |
| AHNAK | AHNAK nucleoprotein | -0.0597173 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0595052 |
| NPAS2 | neuronal PAS domain protein 2 | -0.057769 |
| TNNC1 | troponin C type 1 (slow) | -0.057763 |
| HDLBP | high density lipoprotein binding protein | -0.0543956 |
| FRMD4A | FERM domain containing 4A | -0.0540335 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0529896 |
| FAM20C | family with sequence similarity 20, member C | -0.0522693 |
| RRBP1 | ribosome binding protein 1 | -0.0518399 |
| SP100 | SP100 nuclear antigen | -0.0515766 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0500478 |
| GLIS3 | GLIS family zinc finger 3 | -0.0500091 |
| COL1A1 | collagen, type I, alpha 1 | -0.0497117 |
| FBXO11 | F-box protein 11 | -0.0495813 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0480542 |
| CALU | calumenin | -0.0476988 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0461965 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.045924 |
| CANX | calnexin | -0.0456666 |
| HLA-B | major histocompatibility complex, class I, B | -0.0454786 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0453159 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0447429 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0442938 |
| ANXA2 | annexin A2 | -0.0442216 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0439361 |
| COL4A2 | collagen, type IV, alpha 2 | -0.0435961 |
| RBM39 | RNA binding motif protein 39 | -0.0434908 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0431164 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0421423 |
| IER3 | immediate early response 3 | -0.0415861 |
| TOP1 | topoisomerase (DNA) I | -0.0413697 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0412719 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0398495 |
| SVIL | supervillin | -0.0397182 |
| SENP5 | SUMO1/sentrin specific peptidase 5 | -0.038336 |
| COL1A2 | collagen, type I, alpha 2 | -0.038196 |
| DNAAF9 | dynein axonemal assembly factor 9 | -0.038006 |
| CDK13 | cyclin-dependent kinase 13 | -0.0375561 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0372511 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.0371746 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.036752 |
| HPCAL1 | hippocalcin-like 1 | -0.0364655 |
| PDLIM5 | PDZ and LIM domain 5 | -0.036294 |
| GNAS | GNAS complex locus | -0.0362126 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0358783 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0351583 |
| HMGA2 | high mobility group AT-hook 2 | -0.0345395 |
| HLA-C | major histocompatibility complex, class I, C | -0.0344125 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0338556 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0338213 |
| CAPZB | capping protein (actin filament) muscle Z-line, beta | -0.033708 |
| SCLT1 | sodium channel and clathrin linker 1 | -0.0334143 |
| VCL | vinculin | -0.0334056 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0332281 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0327784 |
| AOPEP | aminopeptidase O (putative) | -0.0326022 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0325548 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0324932 |
| INTS6 | integrator complex subunit 6 | -0.032446 |
| LARP4B | La ribonucleoprotein domain family, member 4B | -0.0323315 |
| FMNL2 | formin-like 2 | -0.0319282 |
| RAB2A | RAB2A, member RAS oncogene family | -0.0315428 |
| ACTN1 | actinin, alpha 1 | -0.0313242 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0312466 |
| NF1 | neurofibromin 1 | -0.0311139 |
| HM13 | histocompatibility (minor) 13 | -0.0309829 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0307961 |
| EGR1 | early growth response 1 | -0.0307502 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0306184 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0305746 |
| TMSB10 | thymosin beta 10 | -0.0305458 |
| GLG1 | golgi glycoprotein 1 | -0.0304331 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0299418 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0296068 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0295627 |
| TJP1 | tight junction protein 1 | -0.0294449 |
| TPM4 | tropomyosin 4 | -0.0292955 |
| PEAK1 | pseudopodium-enriched atypical kinase 1 | -0.0292753 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.0292657 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0292388 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0292382 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0291767 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0291518 |
| GOLGB1 | golgin B1 | -0.0288539 |
| FN1 | fibronectin 1 | -0.0287317 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0284887 |
| ASPH | aspartate beta-hydroxylase | -0.028395 |
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) | -0.0283069 |
| ARF1 | ADP-ribosylation factor 1 | -0.0282813 |
| CHD9 | chromodomain helicase DNA binding protein 9 | -0.0281954 |
| PAX3 | paired box 3 | -0.0280623 |
