| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Omeprazole (sodium) perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Omeprazole (sodium)_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.136938 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.13616 |
| EGFR | epidermal growth factor receptor | 0.101571 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0883031 |
| HDAC9 | histone deacetylase 9 | 0.0791467 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0682081 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0660604 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.0649808 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0636579 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | 0.0617491 |
| EZR | ezrin | 0.0563977 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0498125 |
| FLNB | filamin B, beta | 0.0438241 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0419501 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0411887 |
| SOX6 | SRY (sex determining region Y)-box 6 | 0.0400299 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0380887 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0378354 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0377473 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0374987 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0367296 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | 0.0361912 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0360701 |
| VCL | vinculin | 0.0352733 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.034243 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0339453 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0333085 |
| CCNL1 | cyclin L1 | 0.0331502 |
| MED13 | mediator complex subunit 13 | 0.0331328 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0329074 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0324464 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0324421 |
| SMYD3 | SET and MYND domain containing 3 | 0.031971 |
| RPL3 | ribosomal protein L3 | 0.0319077 |
| ANXA1 | annexin A1 | 0.0317369 |
| FAT1 | FAT atypical cadherin 1 | 0.0307538 |
| PYGB | phosphorylase, glycogen; brain | 0.0306432 |
| CACNB4 | calcium channel, voltage-dependent, beta 4 subunit | 0.0301141 |
| RNF145 | ring finger protein 145 | 0.0296021 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0294276 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0291508 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.0286014 |
| ENOX1 | ecto-NOX disulfide-thiol exchanger 1 | 0.0285069 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0280536 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 0.0279275 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.0272375 |
| PHF3 | PHD finger protein 3 | 0.0269022 |
| GCNT1 | glucosaminyl (N-acetyl) transferase 1, core 2 | 0.0267313 |
| YEATS2 | YEATS domain containing 2 | 0.026325 |
| ZNF638 | zinc finger protein 638 | 0.0262816 |
| NUP58 | nucleoporin 58 | 0.0262015 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0261992 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0260909 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0260851 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0260395 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0257501 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0256062 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0253849 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.025361 |
| FHAD1 | forkhead-associated (FHA) phosphopeptide binding domain 1 | 0.0249499 |
| PRELID2 | PRELI domain containing 2 | 0.0246326 |
| WDR43 | WD repeat domain 43 | 0.024382 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.024331 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.0242301 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 | 0.0242137 |
| MYOF | myoferlin | 0.0241462 |
| TMEM39A | transmembrane protein 39A | 0.0241406 |
| TMF1 | TATA element modulatory factor 1 | 0.0240892 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0236958 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | 0.0234223 |
| FUBP1 | far upstream element (FUSE) binding protein 1 | 0.0233061 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0232642 |
| ZNF292 | zinc finger protein 292 | 0.0231388 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0230071 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0229578 |
| ITSN1 | intersectin 1 (SH3 domain protein) | 0.0228003 |
| PDGFC | platelet derived growth factor C | 0.0227536 |
| SGMS1 | sphingomyelin synthase 1 | 0.022635 |
| SBF2 | SET binding factor 2 | 0.0223436 |
| ASPH | aspartate beta-hydroxylase | 0.0222288 |
| RAB27B | RAB27B, member RAS oncogene family | 0.0220675 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.0219371 |
| SCAF8 | SR-related CTD-associated factor 8 | 0.021823 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0217847 |
| ZNF608 | zinc finger protein 608 | 0.0217406 |
| PLXNA1 | plexin A1 | 0.0215129 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0214346 |
| FOXP1 | forkhead box P1 | 0.0213571 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0211306 |
| MATR3 | matrin 3 | 0.0209443 |
| CALR | calreticulin | 0.0208532 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0207819 |
| EFNA5 | ephrin-A5 | 0.0207678 |
| CSF1 | colony stimulating factor 1 (macrophage) | 0.0206588 |
| RPS2 | ribosomal protein S2 | 0.0205323 |
| ECT2 | epithelial cell transforming 2 | 0.0204795 |
| GOSR2 | golgi SNAP receptor complex member 2 | 0.0203967 |
| PHF21A | PHD finger protein 21A | 0.0203119 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0202356 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | 0.0200964 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.208977 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.142261 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.105484 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.103594 |
| RPS6 | ribosomal protein S6 | -0.0984131 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0963312 |
| AHNAK | AHNAK nucleoprotein | -0.0745505 |
| RPS8 | ribosomal protein S8 | -0.0640623 |
| RPLP1 | ribosomal protein, large, P1 | -0.0610516 |
| S100A6 | S100 calcium binding protein A6 | -0.0584442 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0581935 |
| RPL35A | ribosomal protein L35a | -0.0574744 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0541548 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0486507 |
| RPL34 | ribosomal protein L34 | -0.0482506 |
| RPS23 | ribosomal protein S23 | -0.0463431 |
| RPS24 | ribosomal protein S24 | -0.0448759 |
| RPL19 | ribosomal protein L19 | -0.0441416 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0434602 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.042249 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0415581 |
| RPL12 | ribosomal protein L12 | -0.0414519 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0403233 |
| TMSB4X | thymosin beta 4, X-linked | -0.0397553 |
| RPS27A | ribosomal protein S27a | -0.0396406 |
| RPL31 | ribosomal protein L31 | -0.0370912 |
| MKI67 | marker of proliferation Ki-67 | -0.0367446 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0337297 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0320088 |
| RPS19 | ribosomal protein S19 | -0.0318801 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0315444 |
| ENO1 | enolase 1, (alpha) | -0.0306225 |
| RPL9 | ribosomal protein L9 | -0.0304574 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | -0.0302734 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0298539 |
| RPS14 | ribosomal protein S14 | -0.0294129 |
| HJURP | Holliday junction recognition protein | -0.0293279 |
| RPLP0 | ribosomal protein, large, P0 | -0.029259 |
| RPL23 | ribosomal protein L23 | -0.028811 |
| RPS25 | ribosomal protein S25 | -0.0273664 |
| HDLBP | high density lipoprotein binding protein | -0.0272382 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0267923 |
| RPLP2 | ribosomal protein, large, P2 | -0.0267049 |
| CANX | calnexin | -0.0266098 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0264264 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0262656 |
| HMGB1 | high mobility group box 1 | -0.02606 |
| ACTG1 | actin gamma 1 | -0.0259127 |
| FTL | ferritin, light polypeptide | -0.0257021 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0252082 |
| ABI1 | abl-interactor 1 | -0.0250407 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0245796 |
| DEK | DEK proto-oncogene | -0.0245115 |
| RPL30 | ribosomal protein L30 | -0.0242299 |
| IPO7 | importin 7 | -0.024032 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.024001 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0238581 |
| S100A10 | S100 calcium binding protein A10 | -0.0235257 |
| RPL13A | ribosomal protein L13a | -0.0234062 |
| MT2A | metallothionein 2A | -0.0233941 |
| RPL26 | ribosomal protein L26 | -0.0233159 |
| TPM4 | tropomyosin 4 | -0.0232689 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0230592 |
| TUBB | tubulin, beta class I | -0.0230402 |
| CSE1L | CSE1 chromosome segregation 1-like (yeast) | -0.022399 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0223037 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0222639 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0219643 |
| TXNRD1 | thioredoxin reductase 1 | -0.0218033 |
| RAB3GAP1 | RAB3 GTPase activating protein subunit 1 (catalytic) | -0.0214737 |
| MORF4L2 | mortality factor 4 like 2 | -0.0214381 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | -0.0214321 |
| GCLM | glutamate-cysteine ligase, modifier subunit | -0.0211487 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0210456 |
| SOD1 | superoxide dismutase 1, soluble | -0.0209319 |
| CENPF | centromere protein F, 350/400kDa | -0.020912 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | -0.0209035 |
| RPL28 | ribosomal protein L28 | -0.0206784 |
| RPS20 | ribosomal protein S20 | -0.0202811 |
| RPL32 | ribosomal protein L32 | -0.0201515 |
| RPS13 | ribosomal protein S13 | -0.0198157 |
| DDX18 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 | -0.0194128 |
| SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) | -0.0190986 |
| DIAPH3 | diaphanous-related formin 3 | -0.0189838 |
| CKAP2 | cytoskeleton associated protein 2 | -0.0186971 |
| MZT1 | mitotic spindle organizing protein 1 | -0.0186808 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0186062 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0185448 |
| ANLN | anillin, actin binding protein | -0.0185326 |
| AZIN1 | antizyme inhibitor 1 | -0.0183745 |
| RPL8 | ribosomal protein L8 | -0.0181258 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0180414 |
| RRBP1 | ribosome binding protein 1 | -0.0179358 |
| RTN4 | reticulon 4 | -0.0179154 |
| SDCBP | syndecan binding protein (syntenin) | -0.0177574 |
| TMEM123 | transmembrane protein 123 | -0.0177228 |
| RSRC1 | arginine/serine-rich coiled-coil 1 | -0.0176554 |
| CDCA2 | cell division cycle associated 2 | -0.0175637 |
| MARCHF7 | membrane associated ring-CH-type finger 7 | -0.0174397 |
| NUSAP1 | nucleolar and spindle associated protein 1 | -0.0174119 |
