| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Omeprazole (sodium) perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Omeprazole (sodium)_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0714131 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0694483 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0560838 |
| GOLGA4 | golgin A4 | 0.0544089 |
| MATR3 | matrin 3 | 0.0538794 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0522289 |
| ATP13A3 | ATPase type 13A3 | 0.0485866 |
| TPX2 | TPX2, microtubule-associated | 0.0462514 |
| DNER | delta/notch-like EGF repeat containing | 0.0445834 |
| MIS18BP1 | MIS18 binding protein 1 | 0.0430659 |
| CENPF | centromere protein F, 350/400kDa | 0.0428845 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0411816 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0408512 |
| KIF5B | kinesin family member 5B | 0.0401979 |
| WAC | WW domain containing adaptor with coiled-coil | 0.039727 |
| NUP58 | nucleoporin 58 | 0.0396002 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0379321 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0366625 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0363473 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0362683 |
| ANLN | anillin, actin binding protein | 0.0355378 |
| MSN | moesin | 0.0350216 |
| SRP54 | signal recognition particle 54kDa | 0.0348972 |
| RBM39 | RNA binding motif protein 39 | 0.0327496 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0323895 |
| RNF145 | ring finger protein 145 | 0.0323487 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0323036 |
| MKI67 | marker of proliferation Ki-67 | 0.0320926 |
| DIAPH3 | diaphanous-related formin 3 | 0.032034 |
| ZNF292 | zinc finger protein 292 | 0.0318055 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.031527 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0293669 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0291265 |
| UBQLN1 | ubiquilin 1 | 0.029019 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0289554 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.02888 |
| TFG | TRK-fused gene | 0.0288276 |
| CKAP2 | cytoskeleton associated protein 2 | 0.0286842 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0283482 |
| ECT2 | epithelial cell transforming 2 | 0.0279507 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0277039 |
| CEP295 | centrosomal protein 295kDa | 0.0275232 |
| NAV2 | neuron navigator 2 | 0.026933 |
| WDPCP | WD repeat containing planar cell polarity effector | 0.0268034 |
| TXNRD1 | thioredoxin reductase 1 | 0.0266871 |
| PAPOLA | poly(A) polymerase alpha | 0.0265066 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0264682 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0262979 |
| TENT2 | terminal nucleotidyltransferase 2 | 0.025976 |
| APOLD1 | apolipoprotein L domain containing 1 | 0.0256338 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0255405 |
| PIAS1 | protein inhibitor of activated STAT, 1 | 0.0255239 |
| CAPRIN2 | caprin family member 2 | 0.0254393 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0252827 |
| SGO2 | shugoshin 2 | 0.0252389 |
| BUB1 | BUB1 mitotic checkpoint serine/threonine kinase | 0.025124 |
| COPB1 | coatomer protein complex, subunit beta 1 | 0.0250488 |
| SPAG9 | sperm associated antigen 9 | 0.0250163 |
| MRE11 | MRE11 homolog, double strand break repair nuclease | 0.0250106 |
| WDR43 | WD repeat domain 43 | 0.02501 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.024837 |
| PDS5B | PDS5 cohesin associated factor B | 0.0244533 |
| ANXA1 | annexin A1 | 0.0244455 |
| FAM13A | family with sequence similarity 13, member A | 0.0241774 |
| NCKAP1 | NCK-associated protein 1 | 0.023327 |
| TNPO1 | transportin 1 | 0.0231763 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | 0.0229547 |
| SNX13 | sorting nexin 13 | 0.0229435 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0228227 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0228042 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0227475 |
| ATP11B | ATPase, class VI, type 11B | 0.0227435 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | 0.0227162 |
| ZBTB10 | zinc finger and BTB domain containing 10 | 0.0226972 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0226272 |
| AHCTF1 | AT hook containing transcription factor 1 | 0.0225386 |
| NUP153 | nucleoporin 153kDa | 0.0225136 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.0225087 |
| NSD2 | nuclear receptor binding SET domain protein 2 | 0.0222015 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.022121 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0220224 |
| XPO1 | exportin 1 | 0.0219645 |
| PCNX1 | pecanex 1 | 0.0218996 |
| ZFR | zinc finger RNA binding protein | 0.021737 |
| KIF4A | kinesin family member 4A | 0.0214756 |
| TBK1 | TANK-binding kinase 1 | 0.0214736 |
| IPO5 | importin 5 | 0.0213884 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0213385 |
| AKAP10 | A kinase (PRKA) anchor protein 10 | 0.0213115 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0212046 |
| TPR | translocated promoter region, nuclear basket protein | 0.0211855 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0209587 |
| SRPK2 | SRSF protein kinase 2 | 0.0209137 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0209097 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0208937 |
| BUB3 | BUB3 mitotic checkpoint protein | 0.0208468 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0208362 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0208083 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.020662 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.020661 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TPT1 | tumor protein, translationally-controlled 1 | -0.137662 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.116847 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.110037 |
| TMSB10 | thymosin beta 10 | -0.102724 |
| VIM | vimentin | -0.100782 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0949724 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0747005 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0746693 |
| HMGA2 | high mobility group AT-hook 2 | -0.0741338 |
| ANGPTL4 | angiopoietin-like 4 | -0.0682963 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0620282 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0613115 |
| DST | dystonin | -0.0609501 |
| LDHA | lactate dehydrogenase A | -0.0593982 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.058555 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0578837 |
| SVIL | supervillin | -0.0544454 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0531399 |
| RAI14 | retinoic acid induced 14 | -0.0530757 |
| SDC4 | syndecan 4 | -0.0499311 |
| FMN1 | formin 1 | -0.0494028 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0489467 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0487789 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0482543 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.04746 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0470869 |
| ACTG1 | actin gamma 1 | -0.0462228 |
| AHNAK | AHNAK nucleoprotein | -0.0460668 |
| CD44 | CD44 molecule (Indian blood group) | -0.0457424 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0452169 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0436518 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0423965 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0421562 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.041501 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0414641 |
| RIGI | RNA sensor RIG-I | -0.0411612 |
| SMYD3 | SET and MYND domain containing 3 | -0.0407425 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0400067 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.039999 |
| S100A10 | S100 calcium binding protein A10 | -0.039689 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0394633 |
| PODXL | podocalyxin-like | -0.0389893 |
| JMJD1C | jumonji domain containing 1C | -0.0389673 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0383953 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0382542 |
| ANXA2 | annexin A2 | -0.0381675 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0374111 |
| PRKCA | protein kinase C, alpha | -0.0366999 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0365108 |
| ASPH | aspartate beta-hydroxylase | -0.0360676 |
| PTMA | prothymosin, alpha | -0.0359367 |
| RPL31 | ribosomal protein L31 | -0.0358406 |
| JARID2 | jumonji, AT rich interactive domain 2 | -0.0357744 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0354401 |
| INTS6 | integrator complex subunit 6 | -0.0353754 |
| NALCN | sodium leak channel, non selective | -0.0351002 |
| EGR1 | early growth response 1 | -0.0349691 |
| ATXN1 | ataxin 1 | -0.0331719 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0331048 |
| SETX | senataxin | -0.0327862 |
| ERBIN | erbb2 interacting protein | -0.0323232 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0319848 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.0317642 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | -0.0314127 |
| GPC6 | glypican 6 | -0.0313974 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0313512 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0312949 |
| RPL37 | ribosomal protein L37 | -0.0310272 |
| MT2A | metallothionein 2A | -0.0308705 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0307815 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0304064 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0303603 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0303331 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0302126 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0300513 |
| RPL35A | ribosomal protein L35a | -0.0295415 |
| COL5A1 | collagen, type V, alpha 1 | -0.0294227 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.029358 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0293514 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0293398 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0291784 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | -0.0291377 |
| FBXO11 | F-box protein 11 | -0.0288377 |
| HLA-B | major histocompatibility complex, class I, B | -0.0286014 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0285022 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0282301 |
| AEBP2 | AE binding protein 2 | -0.0280471 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0279801 |
| ZBTB7A | zinc finger and BTB domain containing 7A | -0.0278381 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0274928 |
| GPC5 | glypican 5 | -0.0274794 |
| PRSS23 | protease, serine, 23 | -0.0269993 |
| DLGAP4 | discs, large (Drosophila) homolog-associated protein 4 | -0.0266156 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0263316 |
| EFNA5 | ephrin-A5 | -0.0261783 |
| ITPRID2 | ITPR interacting domain containing 2 | -0.0259887 |
| RPL19 | ribosomal protein L19 | -0.0259112 |
| LMO7 | LIM domain 7 | -0.0259055 |
| RDX | radixin | -0.0256986 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0256242 |
