| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Omeprazole (sodium) perturbation in SW1417 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Omeprazole (sodium)_SW1417 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FTH1 | ferritin, heavy polypeptide 1 | 0.0620258 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | 0.0460727 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.043816 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0402721 |
| CCNL1 | cyclin L1 | 0.0400233 |
| USP3 | ubiquitin specific peptidase 3 | 0.0324767 |
| SNX9 | sorting nexin 9 | 0.0298597 |
| POTEF | POTE ankyrin domain family, member F | 0.0288465 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0271646 |
| CLDN4 | claudin 4 | 0.026339 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | 0.0241416 |
| NCKAP1 | NCK-associated protein 1 | 0.0229161 |
| FAR1 | fatty acyl CoA reductase 1 | 0.0213261 |
| MATR3 | matrin 3 | 0.0211032 |
| CYTH3 | cytohesin 3 | 0.0205728 |
| MKI67 | marker of proliferation Ki-67 | 0.0201748 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0200255 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.019731 |
| ZNF292 | zinc finger protein 292 | 0.0195871 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0181271 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0175235 |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit | 0.0172425 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | 0.0172272 |
| MEF2A | myocyte enhancer factor 2A | 0.0169264 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0167014 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0164624 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.016324 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.0161154 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0160412 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0159207 |
| RNF145 | ring finger protein 145 | 0.015861 |
| ARRDC3 | arrestin domain containing 3 | 0.0157806 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0156382 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0153453 |
| FTL | ferritin, light polypeptide | 0.0152446 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0146969 |
| ZFP36 | ZFP36 ring finger protein | 0.0144755 |
| TXNRD1 | thioredoxin reductase 1 | 0.0143529 |
| SLK | STE20-like kinase | 0.0143386 |
| C1ORF52 | chromosome 1 open reading frame 52 | 0.0143156 |
| ZFAND6 | zinc finger, AN1-type domain 6 | 0.0142693 |
| RTN4 | reticulon 4 | 0.0142617 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0142236 |
| FMR1 | fragile X mental retardation 1 | 0.0142186 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0140348 |
| H1-0 | H1.0 linker histone | 0.013969 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0137306 |
| L1CAM | L1 cell adhesion molecule | 0.0135882 |
| LRRC58 | leucine rich repeat containing 58 | 0.0135236 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0134888 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0134147 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0134053 |
| CLDN3 | claudin 3 | 0.0133773 |
| CDK2AP2 | cyclin-dependent kinase 2 associated protein 2 | 0.0133289 |
| RYK | receptor-like tyrosine kinase | 0.0132876 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0131838 |
| MAL2 | mal, T-cell differentiation protein 2 (gene/pseudogene) | 0.0131734 |
| MYO6 | myosin VI | 0.0131309 |
| HACD2 | 3-hydroxyacyl-CoA dehydratase 2 | 0.0130543 |
| PAFAH1B2 | platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa) | 0.0128762 |
| INSIG1 | insulin induced gene 1 | 0.0127099 |
| CWF19L2 | CWF19-like 2, cell cycle control (S. pombe) | 0.012622 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.012558 |
| BTBD10 | BTB (POZ) domain containing 10 | 0.0125358 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.012472 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0123798 |
| HNRNPH3 | heterogeneous nuclear ribonucleoprotein H3 (2H9) | 0.0123497 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | 0.0122579 |
| CLIP4 | CAP-GLY domain containing linker protein family, member 4 | 0.012224 |
| MIER1 | mesoderm induction early response 1, transcriptional regulator | 0.0121014 |
| TPX2 | TPX2, microtubule-associated | 0.0120972 |
| UBE3A | ubiquitin protein ligase E3A | 0.0119634 |
| LENG8 | leukocyte receptor cluster (LRC) member 8 | 0.0116944 |
| NDUFV2 | NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa | 0.0116873 |
| TFG | TRK-fused gene | 0.0116315 |
| MSMO1 | methylsterol monooxygenase 1 | 0.0116196 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0115919 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0115897 |
| MB21D2 | Mab-21 domain containing 2 | 0.01158 |
| NUP58 | nucleoporin 58 | 0.0115788 |
| FNBP1L | formin binding protein 1-like | 0.011569 |
| RRAS2 | related RAS viral (r-ras) oncogene homolog 2 | 0.0115568 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0115157 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | 0.0114333 |
| IMMP1L | IMP1 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0113368 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0113234 |
| RPRD2 | regulation of nuclear pre-mRNA domain containing 2 | 0.0112326 |
| TMEM41B | transmembrane protein 41B | 0.011137 |
| GORASP2 | golgi reassembly stacking protein 2, 55kDa | 0.0111263 |
| SRPK2 | SRSF protein kinase 2 | 0.0111185 |
| CNOT3 | CCR4-NOT transcription complex, subunit 3 | 0.0110858 |
| CENPE | centromere protein E, 312kDa | 0.011013 |
| MED14 | mediator complex subunit 14 | 0.0110023 |
| AGFG1 | ArfGAP with FG repeats 1 | 0.0109672 |
| TJP2 | tight junction protein 2 | 0.0109568 |
| TMEM39A | transmembrane protein 39A | 0.0108916 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0107161 |
| IL18 | interleukin 18 | 0.0105875 |
| PLEKHF2 | pleckstrin homology domain containing, family F (with FYVE domain) member 2 | 0.0104184 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 | 0.010385 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | -0.132475 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.116824 |
| IFRD1 | interferon-related developmental regulator 1 | -0.0937793 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0936672 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0924156 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0840236 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.0840194 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0805155 |
| EHBP1 | EH domain binding protein 1 | -0.0738431 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0726345 |
| ANXA2 | annexin A2 | -0.0720664 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0698135 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0669481 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0657645 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0653652 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0652682 |
| AHNAK | AHNAK nucleoprotein | -0.0647112 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0588471 |
| CANX | calnexin | -0.0586561 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | -0.058168 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0571418 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0566998 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.056419 |
| VCL | vinculin | -0.0563007 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0551779 |
| NEBL | nebulette | -0.0542899 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0532217 |
| GNAS | GNAS complex locus | -0.0525826 |
| PTMA | prothymosin, alpha | -0.0524285 |
| INTS6 | integrator complex subunit 6 | -0.0523151 |
| EXOC4 | exocyst complex component 4 | -0.0508737 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0495779 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0493246 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.047323 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0472152 |
| PCSK5 | proprotein convertase subtilisin/kexin type 5 | -0.0470519 |
| EZR | ezrin | -0.0469576 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0462196 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0460258 |
| MYO1E | myosin IE | -0.0454968 |
| CUX1 | cut-like homeobox 1 | -0.0452092 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0451046 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.0448969 |
| HDLBP | high density lipoprotein binding protein | -0.0442243 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0442192 |
| CADPS | Ca++-dependent secretion activator | -0.0438056 |
| TMSB10 | thymosin beta 10 | -0.0437162 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0436574 |
| NFIA | nuclear factor I/A | -0.0436514 |
| KRT8 | keratin 8, type II | -0.0432338 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0427575 |
| CDK13 | cyclin-dependent kinase 13 | -0.0421484 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0416814 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0415101 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0408353 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.040083 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0400284 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0398463 |
| HM13 | histocompatibility (minor) 13 | -0.0397781 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0389941 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | -0.0387011 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0386305 |
| EPB41L1 | erythrocyte membrane protein band 4.1-like 1 | -0.0383925 |
| MSI2 | musashi RNA-binding protein 2 | -0.0381224 |
| RIGI | RNA sensor RIG-I | -0.0378817 |
| BZW2 | basic leucine zipper and W2 domains 2 | -0.0377754 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | -0.0374848 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0373944 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.037297 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0371246 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0370235 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | -0.0365963 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0364144 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0358292 |
| RPS6 | ribosomal protein S6 | -0.0355826 |
| SERINC5 | serine incorporator 5 | -0.0355132 |
| RPS24 | ribosomal protein S24 | -0.0354016 |
| CTBP2 | C-terminal binding protein 2 | -0.0353894 |
| TPM4 | tropomyosin 4 | -0.0353563 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0350441 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0347575 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -0.0338541 |
| SQSTM1 | sequestosome 1 | -0.0336137 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0335558 |
| USP34 | ubiquitin specific peptidase 34 | -0.0330657 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0330079 |
| ETV6 | ets variant 6 | -0.0329957 |
| GOLGB1 | golgin B1 | -0.0329434 |
| SHB | Src homology 2 domain containing adaptor protein B | -0.0328956 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0328345 |
| TOP1 | topoisomerase (DNA) I | -0.0327952 |
| RUNX1 | runt-related transcription factor 1 | -0.0326021 |
| MED13 | mediator complex subunit 13 | -0.0323019 |
| FAT1 | FAT atypical cadherin 1 | -0.0321624 |
| SMAD2 | SMAD family member 2 | -0.0320543 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | -0.0320075 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0319355 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.0317925 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 | -0.0316867 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0316206 |
