| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Omeprazole perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Omeprazole_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.145852 |
| B2M | beta-2-microglobulin | 0.144162 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.141852 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | 0.138451 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.117515 |
| LMO7 | LIM domain 7 | 0.115411 |
| RNF213 | ring finger protein 213 | 0.115224 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | 0.10984 |
| EZR | ezrin | 0.109833 |
| ANXA2 | annexin A2 | 0.107618 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.107289 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0982009 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0959863 |
| MX1 | MX dynamin-like GTPase 1 | 0.0922546 |
| ITGA6 | integrin, alpha 6 | 0.0865373 |
| RIGI | RNA sensor RIG-I | 0.0810105 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0739255 |
| SQSTM1 | sequestosome 1 | 0.0729393 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | 0.0716259 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0706318 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0650136 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.064927 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0632631 |
| PKM | pyruvate kinase, muscle | 0.0618727 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0613683 |
| PHF3 | PHD finger protein 3 | 0.0593777 |
| CDHR2 | cadherin-related family member 2 | 0.0592371 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0584941 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.0546259 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0543337 |
| MX2 | MX dynamin-like GTPase 2 | 0.0542343 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | 0.0538541 |
| ENO1 | enolase 1, (alpha) | 0.0536103 |
| SP100 | SP100 nuclear antigen | 0.0529023 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0524631 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0519211 |
| TMC5 | transmembrane channel-like 5 | 0.0513471 |
| EXT1 | exostosin glycosyltransferase 1 | 0.050911 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | 0.0506717 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0504048 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | 0.0499112 |
| PRKCA | protein kinase C, alpha | 0.049882 |
| LYZ | lysozyme | 0.0497271 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0490332 |
| TXNIP | thioredoxin interacting protein | 0.0483514 |
| INTS6 | integrator complex subunit 6 | 0.0481046 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0478395 |
| MCL1 | myeloid cell leukemia 1 | 0.0472472 |
| JUN | jun proto-oncogene | 0.0464794 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0442555 |
| EGR1 | early growth response 1 | 0.0442082 |
| CANX | calnexin | 0.0434175 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0430649 |
| DSPP | dentin sialophosphoprotein | 0.0429896 |
| NPSR1 | neuropeptide S receptor 1 | 0.0422288 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.0419421 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0416622 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | 0.041584 |
| NDRG1 | N-myc downstream regulated 1 | 0.0409014 |
| GOLGB1 | golgin B1 | 0.040675 |
| HLA-E | major histocompatibility complex, class I, E | 0.040264 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0402146 |
| IRF1 | interferon regulatory factor 1 | 0.0399853 |
| PLSCR1 | phospholipid scramblase 1 | 0.0399841 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.039924 |
| IGF1R | insulin-like growth factor 1 receptor | 0.039838 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | 0.0395968 |
| MCU | mitochondrial calcium uniporter | 0.0395162 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0388024 |
| ELOF1 | elongation factor 1 homolog (S. cerevisiae) | 0.0383505 |
| SFTPA2 | surfactant protein A2 | 0.0379284 |
| APOL1 | apolipoprotein L, 1 | 0.0377267 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.037637 |
| PGK1 | phosphoglycerate kinase 1 | 0.0373104 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.03695 |
| TRIM2 | tripartite motif containing 2 | 0.0368652 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0366332 |
| UBC | ubiquitin C | 0.0362559 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | 0.03602 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0359832 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0359825 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0358194 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0356979 |
| ERBIN | erbb2 interacting protein | 0.0350958 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0350105 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0345181 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.0345175 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0344581 |
| PARP9 | poly (ADP-ribose) polymerase family, member 9 | 0.0343667 |
| PERP | PERP, TP53 apoptosis effector | 0.0337717 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | 0.0327935 |
| APOL6 | apolipoprotein L, 6 | 0.0324454 |
| GRK3 | G protein-coupled receptor kinase 3 | 0.0324321 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0321025 |
| ABLIM1 | actin binding LIM protein 1 | 0.0320891 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0317096 |
| CALR | calreticulin | 0.0316564 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.0315431 |
| RRBP1 | ribosome binding protein 1 | 0.031396 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0313052 |
| Symbol | Name | Standardized Value |
|---|---|---|
| RPS6 | ribosomal protein S6 | -0.0547783 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0454438 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0444353 |
| RPL35A | ribosomal protein L35a | -0.033686 |
| RPS8 | ribosomal protein S8 | -0.0303332 |
| RPLP1 | ribosomal protein, large, P1 | -0.028746 |
| RPL34 | ribosomal protein L34 | -0.0278087 |
| RPL23 | ribosomal protein L23 | -0.0254017 |
| RPL37A | ribosomal protein L37a | -0.0241145 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0237404 |
| RPL12 | ribosomal protein L12 | -0.0234157 |
| FTL | ferritin, light polypeptide | -0.0233021 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | -0.0220005 |
| RNF43 | ring finger protein 43 | -0.0217057 |
| RPS24 | ribosomal protein S24 | -0.0213305 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0202703 |
| RPLP0 | ribosomal protein, large, P0 | -0.0199881 |
| RPS19 | ribosomal protein S19 | -0.0191281 |
| RPS3 | ribosomal protein S3 | -0.0187171 |
| RPL30 | ribosomal protein L30 | -0.0184255 |
| RPL19 | ribosomal protein L19 | -0.018329 |
| RPS27 | ribosomal protein S27 | -0.0173353 |
| IFNGR1 | interferon gamma receptor 1 | -0.0167361 |
| GNAS | GNAS complex locus | -0.0163675 |
| RPL37 | ribosomal protein L37 | -0.0162585 |
| RPL31 | ribosomal protein L31 | -0.0159523 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0153981 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | -0.0149454 |
| RPL7A | ribosomal protein L7a | -0.0149359 |
| RPS20 | ribosomal protein S20 | -0.0148766 |
| RPL35 | ribosomal protein L35 | -0.0148485 |
| RPS27A | ribosomal protein S27a | -0.014795 |
| RPS21 | ribosomal protein S21 | -0.0146508 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0146267 |
| RPL9 | ribosomal protein L9 | -0.0145192 |
| TXNRD1 | thioredoxin reductase 1 | -0.0144217 |
| ZDHHC20 | zinc finger, DHHC-type containing 20 | -0.0143079 |
| USP3 | ubiquitin specific peptidase 3 | -0.0138581 |
| RPL11 | ribosomal protein L11 | -0.0137458 |
| RPL36A | ribosomal protein L36a | -0.0136676 |
| RPS16 | ribosomal protein S16 | -0.0135482 |
| RPS29 | ribosomal protein S29 | -0.0135095 |
| RPL26 | ribosomal protein L26 | -0.01311 |
| RPL28 | ribosomal protein L28 | -0.0128927 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | -0.0128122 |
| RACK1 | receptor for activated C kinase 1 | -0.0128033 |
| RPS4X | ribosomal protein S4, X-linked | -0.0127085 |
| ANAPC5 | anaphase promoting complex subunit 5 | -0.0124762 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0123974 |
| CDCP1 | CUB domain containing protein 1 | -0.0120306 |
| BAZ1B | bromodomain adjacent to zinc finger domain, 1B | -0.0119024 |
| RPS25 | ribosomal protein S25 | -0.0118965 |
| RPL27 | ribosomal protein L27 | -0.011874 |
| RPL36 | ribosomal protein L36 | -0.0116952 |
| ATP10B | ATPase, class V, type 10B | -0.0116812 |
| RPL5 | ribosomal protein L5 | -0.0115986 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0114514 |
| RPL18 | ribosomal protein L18 | -0.0114184 |
| PRSS3 | protease, serine, 3 | -0.0112653 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -0.0112532 |
| KYNU | kynureninase | -0.0112484 |
| TMEM165 | transmembrane protein 165 | -0.0112397 |
| MPHOSPH8 | M-phase phosphoprotein 8 | -0.0112367 |
| RPL38 | ribosomal protein L38 | -0.0112364 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0110206 |
| UQCRQ | ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa | -0.010983 |
| RPL13A | ribosomal protein L13a | -0.0109614 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | -0.010928 |
| C6ORF132 | chromosome 6 open reading frame 132 | -0.0108777 |
| FBXO28 | F-box protein 28 | -0.0108176 |
| EFNA5 | ephrin-A5 | -0.0107494 |
| RPS13 | ribosomal protein S13 | -0.0106549 |
| RUNX1 | runt-related transcription factor 1 | -0.0106208 |
| AVL9 | AVL9 homolog (S. cerevisiase) | -0.0106088 |
| VAPA | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa | -0.0105843 |
| RNF145 | ring finger protein 145 | -0.0105792 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0105184 |
| RASA2 | RAS p21 protein activator 2 | -0.0104814 |
| SKIC3 | SKI3 subunit of superkiller complex | -0.0103178 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0102715 |
| ALDH3A1 | aldehyde dehydrogenase 3 family, member A1 | -0.010164 |
| SLC37A1 | solute carrier family 37 (glucose-6-phosphate transporter), member 1 | -0.0100947 |
| SH3RF1 | SH3 domain containing ring finger 1 | -0.0100703 |
| RPS12 | ribosomal protein S12 | -0.0100314 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.00995154 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.00991269 |
| PIBF1 | progesterone immunomodulatory binding factor 1 | -0.00981185 |
| HMGXB4 | HMG box domain containing 4 | -0.00974522 |
| RPL27A | ribosomal protein L27a | -0.00940327 |
| SARNP | SAP domain containing ribonucleoprotein | -0.00938908 |
| RNF149 | ring finger protein 149 | -0.00935013 |
| COG5 | component of oligomeric golgi complex 5 | -0.00926851 |
| SMC4 | structural maintenance of chromosomes 4 | -0.00926085 |
| ZFR | zinc finger RNA binding protein | -0.0092608 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | -0.00922926 |
| YTHDC2 | YTH domain containing 2 | -0.00922715 |
| RPS17 | ribosomal protein S17 | -0.00919891 |
| SFXN1 | sideroflexin 1 | -0.00905257 |
| PPIG | peptidylprolyl isomerase G (cyclophilin G) | -0.0089522 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | -0.00894464 |
