| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Omeprazole perturbation in HS-578T cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Omeprazole_HS-578T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.466401 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.237968 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.125806 |
| COL6A3 | collagen, type VI, alpha 3 | 0.121326 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0842537 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0692758 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0684199 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0641292 |
| ENO1 | enolase 1, (alpha) | 0.0510893 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0487389 |
| LDHA | lactate dehydrogenase A | 0.0479884 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.04428 |
| FBN1 | fibrillin 1 | 0.0364691 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | 0.0351803 |
| CD44 | CD44 molecule (Indian blood group) | 0.0348525 |
| CALR | calreticulin | 0.0334954 |
| COL1A1 | collagen, type I, alpha 1 | 0.0332977 |
| ANXA2 | annexin A2 | 0.032387 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0322135 |
| VCL | vinculin | 0.0317096 |
| UBC | ubiquitin C | 0.0313003 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0293008 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0287978 |
| CLIC4 | chloride intracellular channel 4 | 0.0286388 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0275934 |
| PKM | pyruvate kinase, muscle | 0.0274522 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0252944 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0242717 |
| CANX | calnexin | 0.0242135 |
| AHNAK | AHNAK nucleoprotein | 0.0238405 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0225269 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0221629 |
| RIGI | RNA sensor RIG-I | 0.0219802 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0218958 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0210142 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0205768 |
| ECE1 | endothelin converting enzyme 1 | 0.0204755 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0204328 |
| CADM1 | cell adhesion molecule 1 | 0.0197577 |
| SP100 | SP100 nuclear antigen | 0.0193066 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0192676 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0191238 |
| VCAN | versican | 0.0187579 |
| PLEC | plectin | 0.0186775 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.018618 |
| POSTN | periostin, osteoblast specific factor | 0.0180296 |
| ASPH | aspartate beta-hydroxylase | 0.0177835 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | 0.017489 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | 0.0172123 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0171639 |
| ARRDC3 | arrestin domain containing 3 | 0.0170457 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.016658 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0165419 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | 0.0165029 |
| LOXL2 | lysyl oxidase-like 2 | 0.0164533 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0162193 |
| IL6ST | interleukin 6 signal transducer | 0.0161518 |
| QKI | QKI, KH domain containing, RNA binding | 0.0150483 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0150316 |
| JUN | jun proto-oncogene | 0.0149236 |
| ANXA5 | annexin A5 | 0.0148473 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0147922 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0147778 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0147192 |
| PGK1 | phosphoglycerate kinase 1 | 0.0146915 |
| SQSTM1 | sequestosome 1 | 0.0144555 |
| TAPBP | TAP binding protein (tapasin) | 0.0144281 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0141768 |
| HDLBP | high density lipoprotein binding protein | 0.0140262 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0140135 |
| EGFR | epidermal growth factor receptor | 0.0140112 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0136684 |
| HLA-A | major histocompatibility complex, class I, A | 0.0136082 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | 0.0135942 |
| MAP1B | microtubule-associated protein 1B | 0.0130213 |
| RYBP | RING1 and YY1 binding protein | 0.0128491 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0127953 |
| CALU | calumenin | 0.0126602 |
| HYOU1 | hypoxia up-regulated 1 | 0.0126326 |
| COL4A1 | collagen, type IV, alpha 1 | 0.0124986 |
| ZNF644 | zinc finger protein 644 | 0.0123173 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0121016 |
| MYOF | myoferlin | 0.012093 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0117767 |
| MYO10 | myosin X | 0.0117429 |
| SULF1 | sulfatase 1 | 0.0110407 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0108569 |
| ICAM1 | intercellular adhesion molecule 1 | 0.0108433 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0106271 |
| PIEZO2 | piezo-type mechanosensitive ion channel component 2 | 0.0105944 |
| PSMD2 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 | 0.0105778 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0104032 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0103704 |
| EGR1 | early growth response 1 | 0.0103701 |
| HDAC9 | histone deacetylase 9 | 0.0103358 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0101549 |
| NKAIN3 | Na+/K+ transporting ATPase interacting 3 | 0.0101427 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0101168 |
| MSN | moesin | 0.0101144 |
| BSG | basigin (Ok blood group) | 0.0101068 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | -0.112623 |
| TMSB10 | thymosin beta 10 | -0.0518361 |
| STC1 | stanniocalcin 1 | -0.0474957 |
| RPS6 | ribosomal protein S6 | -0.0448637 |
| PTMA | prothymosin, alpha | -0.042364 |
| RPS3 | ribosomal protein S3 | -0.0390838 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0348003 |
| RPL37A | ribosomal protein L37a | -0.0347658 |
| RPL26 | ribosomal protein L26 | -0.0327563 |
| RPS8 | ribosomal protein S8 | -0.031425 |
| RPS12 | ribosomal protein S12 | -0.0284442 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0281957 |
| RPL36 | ribosomal protein L36 | -0.027893 |
| RPS19 | ribosomal protein S19 | -0.0272006 |
| GOLGA4 | golgin A4 | -0.0238534 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0233024 |
| RPL18 | ribosomal protein L18 | -0.0216919 |
| FTL | ferritin, light polypeptide | -0.0207033 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0204215 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0193544 |
| RPS2 | ribosomal protein S2 | -0.0192652 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0185769 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0181378 |
| RPL23 | ribosomal protein L23 | -0.0177986 |
| SQLE | squalene epoxidase | -0.0175817 |
| RPS25 | ribosomal protein S25 | -0.0170936 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0168175 |
| RPL12 | ribosomal protein L12 | -0.0166384 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0164377 |
| MYO9B | myosin IXB | -0.0164329 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0163849 |
| HMGA2 | high mobility group AT-hook 2 | -0.0161982 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0161679 |
| RPS16 | ribosomal protein S16 | -0.0159519 |
| RPLP2 | ribosomal protein, large, P2 | -0.0157671 |
| RPL32 | ribosomal protein L32 | -0.0157574 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0154167 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | -0.0151091 |
| RPL19 | ribosomal protein L19 | -0.0150739 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0150698 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0149946 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0148335 |
| TMEM165 | transmembrane protein 165 | -0.0146586 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0145104 |
| VIM | vimentin | -0.0144574 |
| PTK2 | protein tyrosine kinase 2 | -0.0142865 |
| S100A6 | S100 calcium binding protein A6 | -0.0140516 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0138386 |
| RPL31 | ribosomal protein L31 | -0.0137768 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0137554 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.013741 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0133655 |
| RPL11 | ribosomal protein L11 | -0.0131707 |
| RPL35A | ribosomal protein L35a | -0.0131651 |
| TNPO1 | transportin 1 | -0.0130628 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0130419 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0130213 |
| IER3 | immediate early response 3 | -0.0130209 |
| RPL5 | ribosomal protein L5 | -0.0129114 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.0127738 |
| RPL37 | ribosomal protein L37 | -0.0126915 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0126708 |
| SBF2 | SET binding factor 2 | -0.0124998 |
| RPLP1 | ribosomal protein, large, P1 | -0.012485 |
| RBM39 | RNA binding motif protein 39 | -0.0124845 |
| RPL9 | ribosomal protein L9 | -0.0124102 |
| NAV2 | neuron navigator 2 | -0.0123815 |
| RPL7 | ribosomal protein L7 | -0.0123767 |
| RPS11 | ribosomal protein S11 | -0.0121103 |
| MTDH | metadherin | -0.0120159 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0119601 |
| OGA | O-GlcNAcase | -0.0119343 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0117106 |
| RBM25 | RNA binding motif protein 25 | -0.0115993 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.011599 |
| TMSB4X | thymosin beta 4, X-linked | -0.011548 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0113971 |
| RPL36A | ribosomal protein L36a | -0.0111683 |
| RPL35 | ribosomal protein L35 | -0.0109508 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0109413 |
| RPL27 | ribosomal protein L27 | -0.0108737 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0108243 |
| EFNA5 | ephrin-A5 | -0.0107979 |
| TPR | translocated promoter region, nuclear basket protein | -0.0106933 |
| CMIP | c-Maf inducing protein | -0.0105895 |
| ANO10 | anoctamin 10 | -0.0105877 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0105587 |
| ATP5F1E | ATP synthase F1 subunit epsilon | -0.0104972 |
| CAVIN1 | caveolae associated protein 1 | -0.0104303 |
| FMNL2 | formin-like 2 | -0.0104277 |
| RPS17 | ribosomal protein S17 | -0.0103749 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0103641 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0102836 |
| SKIC3 | SKI3 subunit of superkiller complex | -0.010125 |
| GGNBP2 | gametogenetin binding protein 2 | -0.0101003 |
| RPS27A | ribosomal protein S27a | -0.0100535 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0100136 |
| CLMP | CXADR-like membrane protein | -0.00996199 |
| IGFBP7 | insulin-like growth factor binding protein 7 | -0.00992913 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.00989865 |
