| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Omeprazole perturbation in Hs 766T cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Omeprazole_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.219878 |
| LMO7 | LIM domain 7 | 0.186524 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.18197 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | 0.144447 |
| DPYD | dihydropyrimidine dehydrogenase | 0.124489 |
| ITGA6 | integrin, alpha 6 | 0.120259 |
| FLNB | filamin B, beta | 0.114524 |
| PDLIM5 | PDZ and LIM domain 5 | 0.106159 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.101091 |
| RASAL2 | RAS protein activator like 2 | 0.0876198 |
| MSN | moesin | 0.0871464 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0865441 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0837539 |
| SLC35F3 | solute carrier family 35, member F3 | 0.0791079 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0766895 |
| CD44 | CD44 molecule (Indian blood group) | 0.0728657 |
| LDHA | lactate dehydrogenase A | 0.0724052 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0697833 |
| PLS3 | plastin 3 | 0.0684027 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0678791 |
| MYOF | myoferlin | 0.0676289 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0669849 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0618665 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0590325 |
| SULF1 | sulfatase 1 | 0.0590263 |
| CDK6 | cyclin-dependent kinase 6 | 0.0585352 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0570181 |
| JMJD1C | jumonji domain containing 1C | 0.0562055 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0560456 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0551452 |
| MYO10 | myosin X | 0.0550206 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0543004 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.0542368 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 0.0538495 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0534092 |
| EMP1 | epithelial membrane protein 1 | 0.0533367 |
| ENO1 | enolase 1, (alpha) | 0.0526279 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0513168 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.0512807 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0503811 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0498175 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0494209 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0492653 |
| NDRG1 | N-myc downstream regulated 1 | 0.047763 |
| PODXL | podocalyxin-like | 0.0477247 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0477212 |
| ASPH | aspartate beta-hydroxylase | 0.0476357 |
| MTSS1 | metastasis suppressor 1 | 0.0475492 |
| RCOR1 | REST corepressor 1 | 0.0475045 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0473146 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.0469246 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0463877 |
| FOXO1 | forkhead box O1 | 0.0463302 |
| PALLD | palladin, cytoskeletal associated protein | 0.0458363 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | 0.0457768 |
| DST | dystonin | 0.044698 |
| AMOTL1 | angiomotin like 1 | 0.0446589 |
| VCL | vinculin | 0.0443799 |
| EZR | ezrin | 0.044012 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0438307 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0433228 |
| INTS6 | integrator complex subunit 6 | 0.0415625 |
| UTRN | utrophin | 0.040888 |
| FN1 | fibronectin 1 | 0.0408328 |
| MECOM | MDS1 and EVI1 complex locus | 0.0406258 |
| ANXA1 | annexin A1 | 0.0406199 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0402899 |
| TGM2 | transglutaminase 2 | 0.0401031 |
| EGFR | epidermal growth factor receptor | 0.0400616 |
| RAI14 | retinoic acid induced 14 | 0.0395518 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0394109 |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) | 0.0386209 |
| LAMC2 | laminin, gamma 2 | 0.0380131 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0378625 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0373826 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.0372966 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.037184 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0367578 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0364986 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0361432 |
| RNF217 | ring finger protein 217 | 0.0359587 |
| MCL1 | myeloid cell leukemia 1 | 0.0359262 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0358327 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0357767 |
| SULF2 | sulfatase 2 | 0.0357661 |
| EFNA5 | ephrin-A5 | 0.0355507 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | 0.0354111 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0353186 |
| DGKH | diacylglycerol kinase, eta | 0.0347893 |
| CALB1 | calbindin 1, 28kDa | 0.0347317 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.0346279 |
| TPM3 | tropomyosin 3 | 0.0345908 |
| HMGA2 | high mobility group AT-hook 2 | 0.0345397 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0341616 |
| FAM107B | family with sequence similarity 107, member B | 0.0339867 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0337398 |
| RIGI | RNA sensor RIG-I | 0.0337107 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0337095 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.033607 |
| POTEF | POTE ankyrin domain family, member F | 0.0334202 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.0867875 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0599589 |
| KIAA1217 | KIAA1217 | -0.053107 |
| MT2A | metallothionein 2A | -0.0471966 |
| RPLP2 | ribosomal protein, large, P2 | -0.044527 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0445149 |
| GNAS | GNAS complex locus | -0.0417636 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | -0.0411372 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0409318 |
| RPS21 | ribosomal protein S21 | -0.0368065 |
| RPS3 | ribosomal protein S3 | -0.036491 |
| PTMA | prothymosin, alpha | -0.0358706 |
| RPS19 | ribosomal protein S19 | -0.0347406 |
| OGA | O-GlcNAcase | -0.0345517 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0321215 |
| RPLP1 | ribosomal protein, large, P1 | -0.031192 |
| RPS24 | ribosomal protein S24 | -0.0311669 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0290064 |
| S100A2 | S100 calcium binding protein A2 | -0.0287988 |
| RPL11 | ribosomal protein L11 | -0.0278223 |
| RPL37A | ribosomal protein L37a | -0.027751 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0274285 |
| LMNA | lamin A/C | -0.0269462 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain | -0.0260592 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0260192 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0259799 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0258828 |
| RPS8 | ribosomal protein S8 | -0.0254503 |
| RPL12 | ribosomal protein L12 | -0.0250356 |
| H1-0 | H1.0 linker histone | -0.0248143 |
| RPS6 | ribosomal protein S6 | -0.0244397 |
| RPL19 | ribosomal protein L19 | -0.0244073 |
| FSCN1 | fascin actin-bundling protein 1 | -0.0241506 |
| ATP5F1E | ATP synthase F1 subunit epsilon | -0.0240689 |
| ALDH3A1 | aldehyde dehydrogenase 3 family, member A1 | -0.0240534 |
| RPS12 | ribosomal protein S12 | -0.0239348 |
| RPL23 | ribosomal protein L23 | -0.0237301 |
| RPL30 | ribosomal protein L30 | -0.0236017 |
| RPL34 | ribosomal protein L34 | -0.0231925 |
| HLA-B | major histocompatibility complex, class I, B | -0.0227311 |
| RPL35A | ribosomal protein L35a | -0.0219981 |
| S100A4 | S100 calcium binding protein A4 | -0.0216731 |
| IER3 | immediate early response 3 | -0.0216483 |
| RPL26 | ribosomal protein L26 | -0.0215778 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0215372 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0212419 |
| RPS27 | ribosomal protein S27 | -0.0209201 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0208627 |
| S100A6 | S100 calcium binding protein A6 | -0.0206122 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0205805 |
| RPL37 | ribosomal protein L37 | -0.0205704 |
| SLC38A1 | solute carrier family 38, member 1 | -0.020379 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0201875 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0196885 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0196481 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.0194471 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0193091 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0191744 |
| RPS29 | ribosomal protein S29 | -0.0191634 |
| RPL36 | ribosomal protein L36 | -0.0190074 |
| PRELID2 | PRELI domain containing 2 | -0.018998 |
| SQLE | squalene epoxidase | -0.0189507 |
| CAVIN1 | caveolae associated protein 1 | -0.0188722 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0185894 |
| RPL35 | ribosomal protein L35 | -0.0184976 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0183815 |
| RPS27A | ribosomal protein S27a | -0.0182013 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.0175286 |
| RLF | rearranged L-myc fusion | -0.0173185 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0172552 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0171672 |
| MATR3 | matrin 3 | -0.017056 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.016833 |
| HYCC2 | hyccin PI4KA lipid kinase complex subunit 2 | -0.0167396 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0167327 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0163576 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | -0.0163222 |
| HMGB1 | high mobility group box 1 | -0.0162897 |
| RPL13A | ribosomal protein L13a | -0.0161475 |
| LIFR | leukemia inhibitory factor receptor alpha | -0.0160081 |
| RBM39 | RNA binding motif protein 39 | -0.015762 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.0155189 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0153839 |
| RPL31 | ribosomal protein L31 | -0.0153711 |
| RPS20 | ribosomal protein S20 | -0.0150863 |
| COX4I1 | cytochrome c oxidase subunit IV isoform 1 | -0.0150828 |
| SEC22A | SEC22 vesicle trafficking protein homolog A (S. cerevisiae) | -0.0147708 |
| ZFR | zinc finger RNA binding protein | -0.0146492 |
| PDGFB | platelet-derived growth factor beta polypeptide | -0.0145413 |
| RPL18 | ribosomal protein L18 | -0.0144906 |
| RPS16 | ribosomal protein S16 | -0.0144297 |
| NDFIP1 | Nedd4 family interacting protein 1 | -0.0142549 |
| HIP1 | huntingtin interacting protein 1 | -0.0141467 |
| MT1X | metallothionein 1X | -0.014131 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0140665 |
| BZW2 | basic leucine zipper and W2 domains 2 | -0.0140066 |
| SMAD3 | SMAD family member 3 | -0.0139269 |
| RPS25 | ribosomal protein S25 | -0.0139096 |
| GM2A | GM2 ganglioside activator | -0.0138813 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | -0.0137733 |