| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Omeprazole perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Omeprazole_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.174334 |
| GOLGA4 | golgin A4 | 0.0960905 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0939412 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0807349 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0712561 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0705376 |
| PCBP2 | poly(rC) binding protein 2 | 0.0691249 |
| GPC6 | glypican 6 | 0.0663087 |
| FAM13A | family with sequence similarity 13, member A | 0.0651282 |
| PRELID2 | PRELI domain containing 2 | 0.0624347 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0597923 |
| CANX | calnexin | 0.0589076 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0556725 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0520791 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0500341 |
| RBM39 | RNA binding motif protein 39 | 0.0493399 |
| MYOF | myoferlin | 0.0456965 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.044614 |
| NCOA7 | nuclear receptor coactivator 7 | 0.0442038 |
| ARF4 | ADP-ribosylation factor 4 | 0.0441156 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0439684 |
| DDIT3 | DNA-damage-inducible transcript 3 | 0.043354 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0398649 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0395972 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.039177 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0372433 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0368717 |
| OS9 | osteosarcoma amplified 9, endoplasmic reticulum lectin | 0.0366566 |
| OGA | O-GlcNAcase | 0.0366036 |
| ZNF292 | zinc finger protein 292 | 0.0362928 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0355287 |
| SRP54 | signal recognition particle 54kDa | 0.0350075 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0346017 |
| CD109 | CD109 molecule | 0.0345524 |
| EZR | ezrin | 0.0340265 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0337058 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0333741 |
| MORF4L2 | mortality factor 4 like 2 | 0.0327085 |
| RAD51B | RAD51 paralog B | 0.032495 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0320684 |
| SQSTM1 | sequestosome 1 | 0.0317715 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0315414 |
| SMAD3 | SMAD family member 3 | 0.0312061 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 0.0310845 |
| FBXL13 | F-box and leucine-rich repeat protein 13 | 0.0307269 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0299602 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0298257 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0297632 |
| COPB1 | coatomer protein complex, subunit beta 1 | 0.0297251 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0295221 |
| NBAS | neuroblastoma amplified sequence | 0.0291997 |
| MCL1 | myeloid cell leukemia 1 | 0.0291134 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0289776 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0286497 |
| COPA | coatomer protein complex, subunit alpha | 0.0286449 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0286136 |
| HDLBP | high density lipoprotein binding protein | 0.0280275 |
| NAV2 | neuron navigator 2 | 0.0276535 |
| MON2 | MON2 homolog (S. cerevisiae) | 0.0275071 |
| SUCO | SUN domain containing ossification factor | 0.0274404 |
| COG5 | component of oligomeric golgi complex 5 | 0.0274084 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0269628 |
| SBF2 | SET binding factor 2 | 0.0269445 |
| NDRG1 | N-myc downstream regulated 1 | 0.026889 |
| ENO1 | enolase 1, (alpha) | 0.0263398 |
| TNNC1 | troponin C type 1 (slow) | 0.0261164 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.0258378 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0256556 |
| SEC24A | SEC24 family member A | 0.0253972 |
| HELZ | helicase with zinc finger | 0.0253107 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0251716 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | 0.0248858 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0247762 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.024776 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.024723 |
| SPAG9 | sperm associated antigen 9 | 0.0246474 |
| LMAN1 | lectin, mannose-binding, 1 | 0.0246287 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0244638 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0240095 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0239318 |
| ASPH | aspartate beta-hydroxylase | 0.0238048 |
| ARRDC3 | arrestin domain containing 3 | 0.0237995 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0237479 |
| YME1L1 | YME1-like 1 ATPase | 0.0237007 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.023599 |
| VCL | vinculin | 0.0234084 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0233849 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0232896 |
| HDAC9 | histone deacetylase 9 | 0.0231579 |
| GDI2 | GDP dissociation inhibitor 2 | 0.0231486 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0231365 |
| TBC1D15 | TBC1 domain family, member 15 | 0.0230374 |
| TP53BP1 | tumor protein p53 binding protein 1 | 0.0224922 |
| VMP1 | vacuole membrane protein 1 | 0.0223627 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0222812 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0221932 |
| CALU | calumenin | 0.0221761 |
| LDHA | lactate dehydrogenase A | 0.0221755 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0221283 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0220672 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.214744 |
| VIM | vimentin | -0.144163 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | -0.106809 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.106536 |
| NRG1 | neuregulin 1 | -0.0991676 |
| MTSS1 | metastasis suppressor 1 | -0.0961268 |
| HMGA2 | high mobility group AT-hook 2 | -0.0909619 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0908814 |
| FTL | ferritin, light polypeptide | -0.0877677 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0877627 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0860233 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0851768 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0819847 |
| CDH13 | cadherin 13 | -0.081359 |
| GLCCI1 | glucocorticoid induced 1 | -0.0798473 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0797512 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0790707 |
| STC1 | stanniocalcin 1 | -0.0789804 |
| MT2A | metallothionein 2A | -0.0785987 |
| NRP1 | neuropilin 1 | -0.0767059 |
| RPLP1 | ribosomal protein, large, P1 | -0.0731051 |
| RPS19 | ribosomal protein S19 | -0.0710984 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0673034 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0635314 |
| S100A6 | S100 calcium binding protein A6 | -0.0614153 |
| RPL36 | ribosomal protein L36 | -0.0595083 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0573588 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0556259 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0555734 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0548729 |
| VRK2 | vaccinia related kinase 2 | -0.054439 |
| CLMP | CXADR-like membrane protein | -0.0543643 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0536796 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0519095 |
| RPS12 | ribosomal protein S12 | -0.0517876 |
| RPS6 | ribosomal protein S6 | -0.0515767 |
| PTMA | prothymosin, alpha | -0.0501285 |
| SNX9 | sorting nexin 9 | -0.0478848 |
| PTK2 | protein tyrosine kinase 2 | -0.0470324 |
| IL1B | interleukin 1, beta | -0.0461288 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0461042 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0444177 |
| RPLP2 | ribosomal protein, large, P2 | -0.0436264 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.0430772 |
| RPL34 | ribosomal protein L34 | -0.0422016 |
| NUMB | numb homolog (Drosophila) | -0.0414312 |
| B2M | beta-2-microglobulin | -0.0411898 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0410974 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0406625 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0403904 |
| PRRX1 | paired related homeobox 1 | -0.0398406 |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) | -0.0388945 |
| RPS21 | ribosomal protein S21 | -0.0387568 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.038017 |
| ZEB2 | zinc finger E-box binding homeobox 2 | -0.0380153 |
| ANXA10 | annexin A10 | -0.0375848 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0373537 |
| CDK14 | cyclin-dependent kinase 14 | -0.0368796 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0365963 |
| OSMR | oncostatin M receptor | -0.0363797 |
| RPL37A | ribosomal protein L37a | -0.0362804 |
| RPL18 | ribosomal protein L18 | -0.0355601 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | -0.0352958 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0351416 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0344545 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.034361 |
| RPL23 | ribosomal protein L23 | -0.0343062 |
| BMERB1 | bMERB domain containing 1 | -0.0342542 |
| MSRB3 | methionine sulfoxide reductase B3 | -0.0341331 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0334587 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | -0.0333796 |
| RPS27 | ribosomal protein S27 | -0.0332976 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0330608 |
| FRMD4A | FERM domain containing 4A | -0.0330013 |
| TMEM165 | transmembrane protein 165 | -0.0329808 |
| RPS8 | ribosomal protein S8 | -0.0329507 |
| RPL35A | ribosomal protein L35a | -0.0325257 |
| WWC2 | WW and C2 domain containing 2 | -0.0324622 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.032257 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | -0.0318504 |
| RPS3 | ribosomal protein S3 | -0.0318477 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0316984 |
| RPL12 | ribosomal protein L12 | -0.0316332 |
| IFI44L | interferon-induced protein 44-like | -0.0312374 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0302176 |
| SIK3 | SIK family kinase 3 | -0.0300998 |
| NAV3 | neuron navigator 3 | -0.0299825 |
| RPL28 | ribosomal protein L28 | -0.0298309 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | -0.0297684 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.029755 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | -0.0297363 |
| RPS29 | ribosomal protein S29 | -0.0295367 |
| ABCA6 | ATP-binding cassette, sub-family A (ABC1), member 6 | -0.0295151 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0294445 |
| FNBP1 | formin binding protein 1 | -0.0294395 |
| GLIS3 | GLIS family zinc finger 3 | -0.0289747 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0289616 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0287829 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0282256 |
| RPL31 | ribosomal protein L31 | -0.02791 |