| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Omeprazole perturbation in NCI-H596 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Omeprazole_NCI-H596 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.252665 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.124862 |
| ENO1 | enolase 1, (alpha) | 0.116538 |
| FNDC3B | fibronectin type III domain containing 3B | 0.113131 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.10125 |
| CALR | calreticulin | 0.0940427 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0911987 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0892268 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0879194 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | 0.0828097 |
| FTL | ferritin, light polypeptide | 0.0822625 |
| SPAG9 | sperm associated antigen 9 | 0.0818145 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0785952 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0778748 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0750628 |
| MED13L | mediator complex subunit 13-like | 0.0747562 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0741765 |
| RRBP1 | ribosome binding protein 1 | 0.0714547 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0712526 |
| AOPEP | aminopeptidase O (putative) | 0.0704923 |
| RPLP0 | ribosomal protein, large, P0 | 0.069897 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0696643 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0693496 |
| PGK1 | phosphoglycerate kinase 1 | 0.068557 |
| PRRC2B | proline-rich coiled-coil 2B | 0.0682784 |
| ZNF292 | zinc finger protein 292 | 0.0679961 |
| PRELID2 | PRELI domain containing 2 | 0.0672886 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0651606 |
| GOLGB1 | golgin B1 | 0.0642001 |
| XPO1 | exportin 1 | 0.0640561 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.0640212 |
| TPM4 | tropomyosin 4 | 0.0633932 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0623327 |
| RAB10 | RAB10, member RAS oncogene family | 0.0619959 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0609464 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0602292 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0602099 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0593357 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0589374 |
| CCNI | cyclin I | 0.0585036 |
| TXNRD1 | thioredoxin reductase 1 | 0.0583507 |
| FMNL2 | formin-like 2 | 0.0577705 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0562502 |
| ATXN2 | ataxin 2 | 0.0559167 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0550401 |
| RPS3 | ribosomal protein S3 | 0.0540406 |
| SLMAP | sarcolemma associated protein | 0.0538886 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0534192 |
| AHNAK | AHNAK nucleoprotein | 0.0521788 |
| PKM | pyruvate kinase, muscle | 0.0520149 |
| COL8A1 | collagen, type VIII, alpha 1 | 0.0517724 |
| RPS12 | ribosomal protein S12 | 0.0516772 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0515087 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.049868 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0498588 |
| LMO7 | LIM domain 7 | 0.0494326 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0493166 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0492359 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0491298 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.0489763 |
| GOLGA4 | golgin A4 | 0.047013 |
| BCL2L1 | BCL2-like 1 | 0.0461343 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0455941 |
| CCNY | cyclin Y | 0.0453871 |
| NOP58 | NOP58 ribonucleoprotein | 0.0448955 |
| FOXP1 | forkhead box P1 | 0.0447107 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0439208 |
| EXOC4 | exocyst complex component 4 | 0.0423692 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0420898 |
| OGA | O-GlcNAcase | 0.0413397 |
| SVIL | supervillin | 0.0410373 |
| PTMA | prothymosin, alpha | 0.0406604 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.0402891 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.0400487 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | 0.0392899 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0386898 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0383589 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0377898 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0376488 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0375415 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0372912 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0367804 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0347883 |
| SRPK2 | SRSF protein kinase 2 | 0.0345339 |
| FLNB | filamin B, beta | 0.0339786 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | 0.0335727 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0307101 |
| TPR | translocated promoter region, nuclear basket protein | 0.0306566 |
| PCBP2 | poly(rC) binding protein 2 | 0.030112 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0298714 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0280513 |
| VMP1 | vacuole membrane protein 1 | 0.0280012 |
| CHD9 | chromodomain helicase DNA binding protein 9 | 0.0277504 |
| SBF2 | SET binding factor 2 | 0.0276715 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0275173 |
| ZNF207 | zinc finger protein 207 | 0.027484 |
| RPL23 | ribosomal protein L23 | 0.0270832 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0261572 |
| PDE10A | phosphodiesterase 10A | 0.0261234 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | 0.0260574 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MYO1E | myosin IE | -0.118952 |
| NDRG1 | N-myc downstream regulated 1 | -0.110778 |
| EFNA5 | ephrin-A5 | -0.100494 |
| GRIK1 | glutamate receptor, ionotropic, kainate 1 | -0.0933543 |
| RORA | RAR-related orphan receptor A | -0.085038 |
| FN1 | fibronectin 1 | -0.0772744 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0749209 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | -0.0749031 |
| FAM13A | family with sequence similarity 13, member A | -0.0741839 |
| DST | dystonin | -0.0718743 |
| ASPH | aspartate beta-hydroxylase | -0.0701097 |
| DTNA | dystrobrevin, alpha | -0.0693261 |
| PRKCA | protein kinase C, alpha | -0.0670141 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0659473 |
| ATXN1 | ataxin 1 | -0.0637778 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0630339 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0607765 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0576944 |
| CUX1 | cut-like homeobox 1 | -0.0575047 |
| SNX14 | sorting nexin 14 | -0.0563089 |
| SEPTIN9 | septin 9 | -0.0545507 |
| BPTF | bromodomain PHD finger transcription factor | -0.0528503 |
| PCBP3 | poly(rC) binding protein 3 | -0.0519004 |
| HMGA2 | high mobility group AT-hook 2 | -0.051303 |
| GPR75-ASB3 | GPR75-ASB3 readthrough | -0.051222 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0509372 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.050823 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0505335 |
| PPP1R10 | protein phosphatase 1, regulatory subunit 10 | -0.049727 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.0494282 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0492897 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0491058 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0485925 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0485705 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0485555 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0484372 |
| MYOF | myoferlin | -0.0481902 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0476264 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0471357 |
| FMN1 | formin 1 | -0.0470553 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0461777 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0458317 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0458089 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | -0.0453001 |
| NRG1 | neuregulin 1 | -0.0443345 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | -0.0431818 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0431115 |
| ADARB2 | adenosine deaminase, RNA-specific, B2 (non-functional) | -0.0422971 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0419989 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0414915 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0404839 |
| NBEAL1 | neurobeachin-like 1 | -0.0402639 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0401259 |
| RNF213 | ring finger protein 213 | -0.0400219 |
| NF1 | neurofibromin 1 | -0.0394224 |
| SMYD3 | SET and MYND domain containing 3 | -0.0389893 |
| COL1A1 | collagen, type I, alpha 1 | -0.0385932 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0385541 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | -0.0370698 |
| NHSL1 | NHS-like 1 | -0.0365078 |
| NAV2 | neuron navigator 2 | -0.0362232 |
| TNNC1 | troponin C type 1 (slow) | -0.0359641 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0356207 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | -0.0355272 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0354756 |
| COG5 | component of oligomeric golgi complex 5 | -0.0350423 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.035041 |
| CD44 | CD44 molecule (Indian blood group) | -0.0342529 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0329103 |
| CMIP | c-Maf inducing protein | -0.0326401 |
| KDELR2 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 | -0.0322942 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | -0.0321719 |
| CAMK2D | calcium/calmodulin-dependent protein kinase II delta | -0.0319418 |
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | -0.0318793 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0318446 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0313912 |
| WASF2 | WAS protein family, member 2 | -0.0297592 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | -0.0297052 |
| RBM39 | RNA binding motif protein 39 | -0.0296338 |
| GPC6 | glypican 6 | -0.029551 |
| YME1L1 | YME1-like 1 ATPase | -0.0294625 |
| NSMCE2 | non-SMC element 2, MMS21 homolog (S. cerevisiae) | -0.0287752 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0284337 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.028319 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0279504 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | -0.0276803 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0276432 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0269632 |
| ZEB2 | zinc finger E-box binding homeobox 2 | -0.0267095 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.0262176 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0258822 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0257659 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0251145 |
| CLTC | clathrin, heavy chain (Hc) | -0.0249886 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0249833 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0248715 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0248022 |
| EGR1 | early growth response 1 | -0.0245259 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0243786 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0238031 |
