| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Omeprazole perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Omeprazole_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL11A1 | collagen, type XI, alpha 1 | 0.0957134 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0783062 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | 0.0611391 |
| VIM | vimentin | 0.0508781 |
| COL5A2 | collagen, type V, alpha 2 | 0.0484814 |
| CADM2 | cell adhesion molecule 2 | 0.043279 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | 0.0410978 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0380023 |
| GPC3 | glypican 3 | 0.035417 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | 0.0345068 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0335123 |
| CTNNA3 | catenin (cadherin-associated protein), alpha 3 | 0.0321299 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | 0.0317165 |
| PCDH9 | protocadherin 9 | 0.030231 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | 0.0295364 |
| PTMA | prothymosin, alpha | 0.0291091 |
| HS3ST5 | heparan sulfate (glucosamine) 3-O-sulfotransferase 5 | 0.0282007 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0276721 |
| HDAC9 | histone deacetylase 9 | 0.0267822 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | 0.0260466 |
| NPAS3 | neuronal PAS domain protein 3 | 0.0248135 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0246085 |
| DST | dystonin | 0.0241999 |
| TRPS1 | trichorhinophalangeal syndrome I | 0.0241084 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0232499 |
| ITGAV | integrin, alpha V | 0.0226649 |
| TENM3 | teneurin transmembrane protein 3 | 0.0218097 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0217825 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0216883 |
| ADGRV1 | adhesion G protein-coupled receptor V1 | 0.0212347 |
| PEG10 | paternally expressed 10 | 0.0208212 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | 0.0206794 |
| THBS1 | thrombospondin 1 | 0.0205787 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0203145 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0195122 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.019434 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0193886 |
| GALNTL6 | polypeptide N-acetylgalactosaminyltransferase-like 6 | 0.0191066 |
| ZNF292 | zinc finger protein 292 | 0.019104 |
| ADGRL3 | adhesion G protein-coupled receptor L3 | 0.0190398 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | 0.0189998 |
| LRRC4C | leucine rich repeat containing 4C | 0.0189767 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.0182223 |
| PLPP1 | phospholipid phosphatase 1 | 0.0179525 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0177581 |
| SMYD3 | SET and MYND domain containing 3 | 0.0176471 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.0174722 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0173649 |
| NCAM2 | neural cell adhesion molecule 2 | 0.01735 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.017225 |
| COL3A1 | collagen, type III, alpha 1 | 0.0171324 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0171195 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0169223 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0169109 |
| CSMD3 | CUB and Sushi multiple domains 3 | 0.0166204 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0165967 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0161408 |
| TNRC6B | trinucleotide repeat containing 6B | 0.0157048 |
| UTRN | utrophin | 0.0156523 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0155327 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.0151637 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0150774 |
| SNX6 | sorting nexin 6 | 0.0149173 |
| ANKRD33B | ankyrin repeat domain 33B | 0.0148844 |
| SYT1 | synaptotagmin I | 0.0148341 |
| NEBL | nebulette | 0.0146005 |
| SPAG9 | sperm associated antigen 9 | 0.0145586 |
| TMSB10 | thymosin beta 10 | 0.0145075 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0142918 |
| MYO10 | myosin X | 0.0141955 |
| TENM2 | teneurin transmembrane protein 2 | 0.014068 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0140255 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0138457 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0137766 |
| PHF3 | PHD finger protein 3 | 0.0137263 |
| ZNF385D | zinc finger protein 385D | 0.0136947 |
| SRP54 | signal recognition particle 54kDa | 0.0136168 |
| COL1A2 | collagen, type I, alpha 2 | 0.0135027 |
| SBF2 | SET binding factor 2 | 0.0134773 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | 0.0133967 |
| MEIS2 | Meis homeobox 2 | 0.0131887 |
| RAD51B | RAD51 paralog B | 0.0131845 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0131415 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0131284 |
| TTC28 | tetratricopeptide repeat domain 28 | 0.013009 |
| KIF5B | kinesin family member 5B | 0.0127781 |
| RAB2A | RAB2A, member RAS oncogene family | 0.0127593 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0126962 |
| PRELID2 | PRELI domain containing 2 | 0.012687 |
| PCDH7 | protocadherin 7 | 0.0125683 |
| SET | SET nuclear proto-oncogene | 0.0125646 |
| RAI1 | retinoic acid induced 1 | 0.012435 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0124265 |
| MAP4 | microtubule-associated protein 4 | 0.0123671 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0123659 |
| PCBP2 | poly(rC) binding protein 2 | 0.012212 |
| STRN3 | striatin, calmodulin binding protein 3 | 0.0121347 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0121306 |
| SRPK2 | SRSF protein kinase 2 | 0.0121261 |
| METAP2 | methionyl aminopeptidase 2 | 0.0120911 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0179317 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0103137 |
| POTEF | POTE ankyrin domain family, member F | -0.00956489 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.00924388 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | -0.00791716 |
| RPLP1 | ribosomal protein, large, P1 | -0.00773027 |
| ATP6V0C | ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c | -0.00765467 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.00725198 |
| RPL39 | ribosomal protein L39 | -0.0068544 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | -0.00631454 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | -0.00611611 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.00611606 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0059255 |
| RPS20 | ribosomal protein S20 | -0.0058942 |
| PER1 | period circadian clock 1 | -0.00581354 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.00576884 |
| RPS15 | ribosomal protein S15 | -0.00562435 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.00547766 |
| CKAP2 | cytoskeleton associated protein 2 | -0.00542859 |
| CYB5R3 | cytochrome b5 reductase 3 | -0.00538614 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.00537645 |
| SUPT16H | suppressor of Ty 16 homolog (S. cerevisiae) | -0.00536227 |
| ZFP36 | ZFP36 ring finger protein | -0.00497903 |
| TSC22D2 | TSC22 domain family, member 2 | -0.00497311 |
| ASTN2 | astrotactin 2 | -0.00494539 |
| RPL35 | ribosomal protein L35 | -0.00489205 |
| RPS5 | ribosomal protein S5 | -0.00488995 |
| H1-10 | H1.10 linker histone | -0.00485732 |
| YBX1 | Y box binding protein 1 | -0.00482158 |
| RNASEH2A | ribonuclease H2, subunit A | -0.00470506 |
| PPP1CC | protein phosphatase 1, catalytic subunit, gamma isozyme | -0.00468566 |
| SNX3 | sorting nexin 3 | -0.00465219 |
| CDC20 | cell division cycle 20 | -0.00461838 |
| ACTN4 | actinin, alpha 4 | -0.00457452 |
| RPL32 | ribosomal protein L32 | -0.00446822 |
| BTG3 | BTG family, member 3 | -0.00446815 |
| RBM3 | RNA binding motif (RNP1, RRM) protein 3 | -0.00446697 |
| DYNC1LI2 | dynein, cytoplasmic 1, light intermediate chain 2 | -0.0043241 |
| GPX1 | glutathione peroxidase 1 | -0.00431077 |
| RNF149 | ring finger protein 149 | -0.0043044 |
| MRE11 | MRE11 homolog, double strand break repair nuclease | -0.00429832 |
| MKI67 | marker of proliferation Ki-67 | -0.00421095 |
| RIGI | RNA sensor RIG-I | -0.0041822 |
| RNPS1 | RNA binding protein S1, serine-rich domain | -0.00418185 |
| BRPF3 | bromodomain and PHD finger containing, 3 | -0.00417941 |
| PLP2 | proteolipid protein 2 (colonic epithelium-enriched) | -0.00413764 |
| RPL34 | ribosomal protein L34 | -0.00412242 |
| H2BC5 | H2B clustered histone 5 | -0.0041194 |
| GABARAP | GABA(A) receptor-associated protein | -0.00411785 |
| HECTD4 | HECT domain containing E3 ubiquitin protein ligase 4 | -0.0041025 |
| DROSHA | drosha, ribonuclease type III | -0.00408114 |
| SYDE2 | synapse defective 1, Rho GTPase, homolog 2 (C. elegans) | -0.00408097 |
| NGFR | nerve growth factor receptor | -0.00408013 |
| EIF3D | eukaryotic translation initiation factor 3, subunit D | -0.004071 |
| TCERG1 | transcription elongation regulator 1 | -0.00406425 |
| UBB | ubiquitin B | -0.00405539 |
| TUBB2A | tubulin, beta 2A class IIa | -0.00400614 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.00397458 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | -0.0039698 |
| DKC1 | dyskeratosis congenita 1, dyskerin | -0.00396439 |
| PSMA2 | proteasome (prosome, macropain) subunit, alpha type, 2 | -0.00395255 |
| CRKL | v-crk avian sarcoma virus CT10 oncogene homolog-like | -0.00394363 |
| ACTN1 | actinin, alpha 1 | -0.00392769 |
| ZNF106 | zinc finger protein 106 | -0.00391312 |
| GPN3 | GPN-loop GTPase 3 | -0.00388498 |
| KIF21A | kinesin family member 21A | -0.00386691 |
| COX5A | cytochrome c oxidase subunit Va | -0.00386584 |
| ASXL2 | additional sex combs like transcriptional regulator 2 | -0.00386571 |
| QPRT | quinolinate phosphoribosyltransferase | -0.00384894 |
| KLHL24 | kelch-like family member 24 | -0.00383329 |
| OSR2 | odd-skipped related transciption factor 2 | -0.00381587 |
| PHB2 | prohibitin 2 | -0.00380986 |
| TARS1 | threonyl-tRNA synthetase 1 | -0.00380983 |
| VBP1 | von Hippel-Lindau binding protein 1 | -0.00380234 |
| CDK17 | cyclin-dependent kinase 17 | -0.00379922 |
| RPLP0 | ribosomal protein, large, P0 | -0.00379554 |
| MFGE8 | milk fat globule-EGF factor 8 protein | -0.00378096 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.00375944 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.00375488 |
| RPL38 | ribosomal protein L38 | -0.00371258 |
| FSCN1 | fascin actin-bundling protein 1 | -0.00369622 |
| CFAP20 | cilia and flagella associated protein 20 | -0.00368022 |
| NELFA | negative elongation factor complex member A | -0.00367015 |
| GART | phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase | -0.00363039 |
| GADD45B | growth arrest and DNA-damage-inducible, beta | -0.00362406 |
| SVIL | supervillin | -0.00362043 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.00361313 |
| PELP1 | proline, glutamate and leucine rich protein 1 | -0.00360203 |
| CKB | creatine kinase, brain | -0.00359769 |
| COQ10B | coenzyme Q10 homolog B (S. cerevisiae) | -0.003596 |
| MAPK1IP1L | mitogen-activated protein kinase 1 interacting protein 1-like | -0.0035955 |
| TMEM230 | transmembrane protein 230 | -0.00359536 |
| PTBP1 | polypyrimidine tract binding protein 1 | -0.00358376 |
| AREL1 | apoptosis resistant E3 ubiquitin protein ligase 1 | -0.00357925 |
| SLC6A4 | solute carrier family 6 (neurotransmitter transporter), member 4 | -0.00357774 |
| PIGT | phosphatidylinositol glycan anchor biosynthesis, class T | -0.00347904 |
| MRPS24 | mitochondrial ribosomal protein S24 | -0.00346718 |
| HDIP1 | HDAC and MIER1 interacting protein 1 | -0.0034602 |
| NHEJ1 | nonhomologous end-joining factor 1 | -0.0034535 |
| LDLRAD4 | low density lipoprotein receptor class A domain containing 4 | -0.00344814 |
