Omeprazole_SNU-1 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Omeprazole perturbation in SNU-1 cell line (Tahoe Therapeutics)
Similar Terms
Downloads & Tools

Genes

200 genes differentially expressed following the Omeprazole_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
PDE4B phosphodiesterase 4B, cAMP-specific 0.234763
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 0.151542
RBMS3 RNA binding motif, single stranded interacting protein 3 0.147287
TJP1 tight junction protein 1 0.109722
SOX6 SRY (sex determining region Y)-box 6 0.109103
EZR ezrin 0.101711
CPED1 cadherin-like and PC-esterase domain containing 1 0.100164
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive 0.0945375
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 0.0788291
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 0.0740224
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 0.0729388
CENPF centromere protein F, 350/400kDa 0.0717305
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like) 0.0716379
NAV2 neuron navigator 2 0.0713772
GNPDA1 glucosamine-6-phosphate deaminase 1 0.0689468
RBPJ recombination signal binding protein for immunoglobulin kappa J region 0.0681947
ADAM10 ADAM metallopeptidase domain 10 0.0657136
NBEA neurobeachin 0.0654538
SSBP2 single-stranded DNA binding protein 2 0.0628215
HDAC9 histone deacetylase 9 0.0625783
ECT2 epithelial cell transforming 2 0.0618717
ZNF292 zinc finger protein 292 0.060101
PCBP2 poly(rC) binding protein 2 0.0578782
EML4 echinoderm microtubule associated protein like 4 0.0573415
ENO1 enolase 1, (alpha) 0.0570574
B3GALT1 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 0.0568591
VCL vinculin 0.0558433
PRELID2 PRELI domain containing 2 0.0556853
EEF1A1 eukaryotic translation elongation factor 1 alpha 1 0.0516742
FOXP1 forkhead box P1 0.0511335
EVI5 ecotropic viral integration site 5 0.0510036
TOP2A topoisomerase (DNA) II alpha 170kDa 0.0492383
HELZ helicase with zinc finger 0.0488704
CAMTA1 calmodulin binding transcription activator 1 0.048029
FNDC3B fibronectin type III domain containing 3B 0.0471986
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like 0.0471471
DLG1 discs, large homolog 1 (Drosophila) 0.0464975
SMC4 structural maintenance of chromosomes 4 0.0460032
PABPC1 poly(A) binding protein, cytoplasmic 1 0.0456297
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) 0.0450982
GBE1 glucan (1,4-alpha-), branching enzyme 1 0.044595
ANXA1 annexin A1 0.0442604
RPL3 ribosomal protein L3 0.0439686
MKI67 marker of proliferation Ki-67 0.0437608
BMP10 bone morphogenetic protein 10 0.0435334
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) 0.0434316
KDM3A lysine (K)-specific demethylase 3A 0.0433163
TGFBR3 transforming growth factor, beta receptor III 0.0431932
CACNB4 calcium channel, voltage-dependent, beta 4 subunit 0.0430189
UBR5 ubiquitin protein ligase E3 component n-recognin 5 0.0423537
EIF4A2 eukaryotic translation initiation factor 4A2 0.0421209
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box) 0.0417375
CANX calnexin 0.0415607
FAT1 FAT atypical cadherin 1 0.0414775
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 0.041455
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme 0.0414073
NPAS2 neuronal PAS domain protein 2 0.0409422
QKI QKI, KH domain containing, RNA binding 0.0399464
HIVEP2 human immunodeficiency virus type I enhancer binding protein 2 0.0396083
KMT2E lysine (K)-specific methyltransferase 2E 0.0390923
FAM13A family with sequence similarity 13, member A 0.0390576
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A 0.0387634
CALR calreticulin 0.038297
DPYD dihydropyrimidine dehydrogenase 0.0379952
ZEB1 zinc finger E-box binding homeobox 1 0.0378794
CAMK1D calcium/calmodulin-dependent protein kinase ID 0.0371107
SPTBN1 spectrin, beta, non-erythrocytic 1 0.0370969
HNRNPA3 heterogeneous nuclear ribonucleoprotein A3 0.0364837
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 0.0360075
RAD18 RAD18 E3 ubiquitin protein ligase 0.0353139
HJURP Holliday junction recognition protein 0.0351539
TAC4 tachykinin 4 (hemokinin) 0.0350841
DSCAM Down syndrome cell adhesion molecule 0.0349304
APLP2 amyloid beta (A4) precursor-like protein 2 0.0344561
ASPH aspartate beta-hydroxylase 0.0343787
PDGFC platelet derived growth factor C 0.0337888
SET SET nuclear proto-oncogene 0.0337548
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2 0.0336161
KDM4C lysine (K)-specific demethylase 4C 0.03344
PPM1L protein phosphatase, Mg2+/Mn2+ dependent, 1L 0.0329676
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.0328553
PPP1R15A protein phosphatase 1, regulatory subunit 15A 0.0323585
P4HB prolyl 4-hydroxylase, beta polypeptide 0.0323056
EXOC6B exocyst complex component 6B 0.0322641
GFPT1 glutamine--fructose-6-phosphate transaminase 1 0.0319069
MBNL1 muscleblind-like splicing regulator 1 0.0315455
RCOR1 REST corepressor 1 0.0314802
MYCBP2 MYC binding protein 2, E3 ubiquitin protein ligase 0.031285
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 0.0312486
KTN1 kinectin 1 (kinesin receptor) 0.0312308
NAB1 NGFI-A binding protein 1 (EGR1 binding protein 1) 0.0311038
TXNIP thioredoxin interacting protein 0.0310851
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I 0.0308257
NFIA nuclear factor I/A 0.0307957
ZNF608 zinc finger protein 608 0.0307578
PDIA3 protein disulfide isomerase family A, member 3 0.0306925
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 0.0306779
ERO1A endoplasmic reticulum oxidoreductase 1 alpha 0.030442
SRRM2 serine/arginine repetitive matrix 2 0.0304096
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A 0.0303965

decreased expression

Symbol Name Standardized Value
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.143118
TPT1 tumor protein, translationally-controlled 1 -0.0960801
RPS6 ribosomal protein S6 -0.0937332
RPL35A ribosomal protein L35a -0.0783447
RPS8 ribosomal protein S8 -0.065732
RPLP1 ribosomal protein, large, P1 -0.0616273
S100A6 S100 calcium binding protein A6 -0.0561644
PTMA prothymosin, alpha -0.0559165
ACTG1 actin gamma 1 -0.0551013
RPL9 ribosomal protein L9 -0.0548233
RPLP2 ribosomal protein, large, P2 -0.0527517
RPL34 ribosomal protein L34 -0.0454855
RPL26 ribosomal protein L26 -0.044802
ANK2 ankyrin 2, neuronal -0.0430497
RPL23 ribosomal protein L23 -0.0427554
RPS25 ribosomal protein S25 -0.0415291
RPL12 ribosomal protein L12 -0.0401757
RPS19 ribosomal protein S19 -0.0401056
ARL4C ADP-ribosylation factor-like 4C -0.0399318
RPL37A ribosomal protein L37a -0.0396515
RPL11 ribosomal protein L11 -0.0380469
PDE4D phosphodiesterase 4D, cAMP-specific -0.037986
RPS12 ribosomal protein S12 -0.0365841
DOCK3 dedicator of cytokinesis 3 -0.0358947
RPL4 ribosomal protein L4 -0.0350312
OSMR oncostatin M receptor -0.0349827
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 -0.0349807
EIF1 eukaryotic translation initiation factor 1 -0.0349291
RPS27A ribosomal protein S27a -0.033937
RPS3 ribosomal protein S3 -0.0325003
RPS23 ribosomal protein S23 -0.0323493
RPL36 ribosomal protein L36 -0.0323161
RPS21 ribosomal protein S21 -0.032306
LOC112694756 uncharaterized LOC112694756 -0.0315738
ATF4 activating transcription factor 4 -0.0313254
RPL31 ribosomal protein L31 -0.030344
RPL19 ribosomal protein L19 -0.0302398
EIF2S2 eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa -0.0301978
RTN4 reticulon 4 -0.0301695
RPS13 ribosomal protein S13 -0.0296068
RPS24 ribosomal protein S24 -0.0293395
RPL7A ribosomal protein L7a -0.028658
RPL13A ribosomal protein L13a -0.0284913
RPL30 ribosomal protein L30 -0.0283612
TXNRD1 thioredoxin reductase 1 -0.0282787
RPS16 ribosomal protein S16 -0.0280632
HLA-B major histocompatibility complex, class I, B -0.0276577
TMSB10 thymosin beta 10 -0.0276142
CMSS1 cms1 ribosomal small subunit homolog (yeast) -0.0270225
RPS14 ribosomal protein S14 -0.0269671
RPL18 ribosomal protein L18 -0.0269655
RACK1 receptor for activated C kinase 1 -0.0268284
TAF1D TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa -0.02637
RPL28 ribosomal protein L28 -0.0251602
RPS29 ribosomal protein S29 -0.0250132
RPL36A ribosomal protein L36a -0.0244746
RPS20 ribosomal protein S20 -0.0243669
GARS1 glycyl-tRNA synthetase 1 -0.0239549
PYGB phosphorylase, glycogen; brain -0.0234914
RPL32 ribosomal protein L32 -0.0234136
ASNS asparagine synthetase (glutamine-hydrolyzing) -0.0228202
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) -0.0225628
RPL17-C18ORF32 RPL17-C18orf32 readthrough -0.0225498
ATP9B ATPase, class II, type 9B -0.0224734
UQCRB ubiquinol-cytochrome c reductase binding protein -0.0210555
S100A4 S100 calcium binding protein A4 -0.0209021
WARS1 tryptophanyl-tRNA synthetase 1 -0.0208224
ZBTB20 zinc finger and BTB domain containing 20 -0.0203606
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) -0.0198135
FTL ferritin, light polypeptide -0.0195706
RPL35 ribosomal protein L35 -0.0192233
ZFAND3 zinc finger, AN1-type domain 3 -0.0192139
RPS4X ribosomal protein S4, X-linked -0.0190538
S100A10 S100 calcium binding protein A10 -0.0190086
PRMT2 protein arginine methyltransferase 2 -0.0188115
RPS5 ribosomal protein S5 -0.0185154
COG5 component of oligomeric golgi complex 5 -0.0184493
NACA nascent polypeptide-associated complex alpha subunit -0.0182785
PARP14 poly (ADP-ribose) polymerase family, member 14 -0.0182573
MTAP methylthioadenosine phosphorylase -0.0181205
RPLP0 ribosomal protein, large, P0 -0.0179429
ADNP activity-dependent neuroprotector homeobox -0.0176995
RPL38 ribosomal protein L38 -0.0173038
BBS9 Bardet-Biedl syndrome 9 -0.0172663
NCEH1 neutral cholesterol ester hydrolase 1 -0.0172638
RPL37 ribosomal protein L37 -0.0172618
RPS17 ribosomal protein S17 -0.016971
RPL5 ribosomal protein L5 -0.0168397
MT2A metallothionein 2A -0.0168382
EXT1 exostosin glycosyltransferase 1 -0.0167047
RPS28 ribosomal protein S28 -0.0166737
EIF4G3 eukaryotic translation initiation factor 4 gamma, 3 -0.0166576
PFN1 profilin 1 -0.0163233
RPS27 ribosomal protein S27 -0.0160105
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1 -0.015915
PHF14 PHD finger protein 14 -0.0158927
PRDX2 peroxiredoxin 2 -0.0156953
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta -0.0155528
MYL12B myosin, light chain 12B, regulatory -0.0154837
KLF3 Kruppel-like factor 3 (basic) -0.0153254