| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Omeprazole perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Omeprazole_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SOD2 | superoxide dismutase 2, mitochondrial | 0.310127 |
| FN1 | fibronectin 1 | 0.245856 |
| FRMD4A | FERM domain containing 4A | 0.120704 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.116249 |
| PDE10A | phosphodiesterase 10A | 0.0995995 |
| CADM1 | cell adhesion molecule 1 | 0.0913909 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0913139 |
| VCAN | versican | 0.0848088 |
| DST | dystonin | 0.083634 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0815717 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0777327 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0743471 |
| PGK1 | phosphoglycerate kinase 1 | 0.0729206 |
| SFTPA2 | surfactant protein A2 | 0.0635739 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0629071 |
| MYOF | myoferlin | 0.0623551 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0619639 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0596242 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0591477 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0581478 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.058111 |
| ADM | adrenomedullin | 0.0554964 |
| CANX | calnexin | 0.0544597 |
| GRIN2A | glutamate receptor, ionotropic, N-methyl D-aspartate 2A | 0.0536486 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0534021 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0524811 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0523853 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0496975 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0493191 |
| ZNF292 | zinc finger protein 292 | 0.0491229 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0490401 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0473767 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | 0.0470344 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | 0.0463395 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.044006 |
| TNS3 | tensin 3 | 0.0431619 |
| LDHA | lactate dehydrogenase A | 0.0424327 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0416417 |
| CLIC4 | chloride intracellular channel 4 | 0.0415998 |
| HLA-E | major histocompatibility complex, class I, E | 0.0415634 |
| VIM | vimentin | 0.0407468 |
| PLIN2 | perilipin 2 | 0.0393939 |
| VCL | vinculin | 0.0386128 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0384175 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0378255 |
| SQSTM1 | sequestosome 1 | 0.0376131 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0376016 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0374574 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.037227 |
| RIGI | RNA sensor RIG-I | 0.0369808 |
| PHF21A | PHD finger protein 21A | 0.0365794 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0362563 |
| AHNAK | AHNAK nucleoprotein | 0.035502 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0354081 |
| SPAG9 | sperm associated antigen 9 | 0.0346486 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0336039 |
| STAG2 | stromal antigen 2 | 0.033424 |
| ATP13A3 | ATPase type 13A3 | 0.0329229 |
| RNF213 | ring finger protein 213 | 0.0328287 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0326218 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0316653 |
| OPTN | optineurin | 0.0312964 |
| QKI | QKI, KH domain containing, RNA binding | 0.031265 |
| RAI14 | retinoic acid induced 14 | 0.0311864 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0311087 |
| LAMP2 | lysosomal-associated membrane protein 2 | 0.0307829 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0304751 |
| OGA | O-GlcNAcase | 0.030147 |
| RTN4 | reticulon 4 | 0.0301248 |
| ARRDC3 | arrestin domain containing 3 | 0.0299514 |
| ENO1 | enolase 1, (alpha) | 0.0296398 |
| RND3 | Rho family GTPase 3 | 0.029635 |
| WDFY1 | WD repeat and FYVE domain containing 1 | 0.0296252 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0296028 |
| RBM39 | RNA binding motif protein 39 | 0.0294188 |
| KIF13A | kinesin family member 13A | 0.0291606 |
| MSN | moesin | 0.0290171 |
| JMJD1C | jumonji domain containing 1C | 0.0289219 |
| DIAPH2 | diaphanous-related formin 2 | 0.0288211 |
| LRRC7 | leucine rich repeat containing 7 | 0.0287651 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0287396 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0286089 |
| APP | amyloid beta (A4) precursor protein | 0.0285445 |
| ICAM1 | intercellular adhesion molecule 1 | 0.0283727 |
| C3 | complement component 3 | 0.0277722 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0276853 |
| JUN | jun proto-oncogene | 0.027595 |
| ANXA2 | annexin A2 | 0.0274962 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0274207 |
| ARF4 | ADP-ribosylation factor 4 | 0.0273474 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0271989 |
| VEGFA | vascular endothelial growth factor A | 0.0270559 |
| MMP12 | matrix metallopeptidase 12 | 0.0268672 |
| MX1 | MX dynamin-like GTPase 1 | 0.0266632 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.0265766 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0263166 |
| NDRG1 | N-myc downstream regulated 1 | 0.0260964 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0260054 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0259431 |
| CTSB | cathepsin B | 0.0258895 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | -0.0913241 |
| TMSB10 | thymosin beta 10 | -0.0797423 |
| RPS6 | ribosomal protein S6 | -0.0696612 |
| RPS12 | ribosomal protein S12 | -0.0628175 |
| FTL | ferritin, light polypeptide | -0.0611189 |
| RPS3 | ribosomal protein S3 | -0.0569019 |
| RPL23 | ribosomal protein L23 | -0.0515128 |
| RPS8 | ribosomal protein S8 | -0.0514735 |
| RPLP2 | ribosomal protein, large, P2 | -0.0509406 |
| RPLP1 | ribosomal protein, large, P1 | -0.0506404 |
| RPL12 | ribosomal protein L12 | -0.0451525 |
| RPL37A | ribosomal protein L37a | -0.0448363 |
| RPL26 | ribosomal protein L26 | -0.0443333 |
| RPS19 | ribosomal protein S19 | -0.0434013 |
| RPL9 | ribosomal protein L9 | -0.0416086 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0415466 |
| RPL35A | ribosomal protein L35a | -0.0410028 |
| RPL36 | ribosomal protein L36 | -0.0380791 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0365383 |
| RPS24 | ribosomal protein S24 | -0.036105 |
| RPL19 | ribosomal protein L19 | -0.035351 |
| RPS4X | ribosomal protein S4, X-linked | -0.0341143 |
| RPL5 | ribosomal protein L5 | -0.0331068 |
| RPL7A | ribosomal protein L7a | -0.0317226 |
| RPS25 | ribosomal protein S25 | -0.0299964 |
| RPL35 | ribosomal protein L35 | -0.0292437 |
| RPL11 | ribosomal protein L11 | -0.0289934 |
| HLA-B | major histocompatibility complex, class I, B | -0.028389 |
| RPS14 | ribosomal protein S14 | -0.0276833 |
| RPL28 | ribosomal protein L28 | -0.0256677 |
| RPL36A | ribosomal protein L36a | -0.0251424 |
| RPS10 | ribosomal protein S10 | -0.0249386 |
| RPS16 | ribosomal protein S16 | -0.0247042 |
| RPL31 | ribosomal protein L31 | -0.0243412 |
| RPS17 | ribosomal protein S17 | -0.0243236 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0242961 |
| RPS27A | ribosomal protein S27a | -0.0241301 |
| RPL7 | ribosomal protein L7 | -0.0237552 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0236868 |
| RPL27 | ribosomal protein L27 | -0.0232217 |
| RPL32 | ribosomal protein L32 | -0.0227834 |
| ACTG1 | actin gamma 1 | -0.0225598 |
| RPS29 | ribosomal protein S29 | -0.0221742 |
| RACK1 | receptor for activated C kinase 1 | -0.0212916 |
| RPS13 | ribosomal protein S13 | -0.0210841 |
| RPL37 | ribosomal protein L37 | -0.0206077 |
| HMGA2 | high mobility group AT-hook 2 | -0.0205688 |
| RPL18 | ribosomal protein L18 | -0.0205538 |
| RPS23 | ribosomal protein S23 | -0.0200837 |
| RPL27A | ribosomal protein L27a | -0.0196681 |
| RPS5 | ribosomal protein S5 | -0.0183295 |
| RPS21 | ribosomal protein S21 | -0.0182407 |
| RPL34 | ribosomal protein L34 | -0.0177114 |
| RPL30 | ribosomal protein L30 | -0.0176234 |
| RPS20 | ribosomal protein S20 | -0.01753 |
| RPS27 | ribosomal protein S27 | -0.0174719 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | -0.017015 |
| ATP5F1E | ATP synthase F1 subunit epsilon | -0.0168194 |
| RPS2 | ribosomal protein S2 | -0.0163123 |
| RPL10A | ribosomal protein L10a | -0.0162253 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0162161 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0161976 |
| RPLP0 | ribosomal protein, large, P0 | -0.0158034 |
| INTS6 | integrator complex subunit 6 | -0.0156303 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0154601 |
| RPS15 | ribosomal protein S15 | -0.0149911 |
| UBA52 | ubiquitin A-52 residue ribosomal protein fusion product 1 | -0.0148492 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.0147438 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0147387 |
| PFN1 | profilin 1 | -0.0146207 |
| RPL21 | ribosomal protein L21 | -0.0135751 |
| RPL13A | ribosomal protein L13a | -0.0135523 |
| COX4I1 | cytochrome c oxidase subunit IV isoform 1 | -0.0132332 |
| UBB | ubiquitin B | -0.0129611 |
| PTMA | prothymosin, alpha | -0.0129533 |
| RPL15 | ribosomal protein L15 | -0.0128447 |
| RPL38 | ribosomal protein L38 | -0.0127454 |
| RPL8 | ribosomal protein L8 | -0.0123291 |
| S100A9 | S100 calcium binding protein A9 | -0.0122259 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | -0.012154 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0119184 |
| RPL39 | ribosomal protein L39 | -0.0119044 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0117724 |
| RPS11 | ribosomal protein S11 | -0.0116425 |
| POTEF | POTE ankyrin domain family, member F | -0.0116262 |
| EEF1D | eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) | -0.011607 |
| HMGB1 | high mobility group box 1 | -0.0111785 |
| ASTN2 | astrotactin 2 | -0.0111479 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0109429 |
| RPL23A | ribosomal protein L23a | -0.010849 |
| HMGA1 | high mobility group AT-hook 1 | -0.0105978 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0104547 |
| SLC25A3 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3 | -0.0103057 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.01023 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0101069 |
| FAU | Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed | -0.00977227 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.00966911 |
| NME2 | NME/NM23 nucleoside diphosphate kinase 2 | -0.00955796 |
| GPX4 | glutathione peroxidase 4 | -0.0092344 |
| MT1X | metallothionein 1X | -0.00922195 |