| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Omeprazole perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Omeprazole_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL6A3 | collagen, type VI, alpha 3 | 0.242388 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.21622 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.119777 |
| FN1 | fibronectin 1 | 0.11176 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.0738902 |
| VIM | vimentin | 0.0666086 |
| B2M | beta-2-microglobulin | 0.06338 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0609912 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0593307 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0584135 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0580827 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.057379 |
| STC1 | stanniocalcin 1 | 0.0559815 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0557477 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0543374 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0527781 |
| CALR | calreticulin | 0.0523739 |
| ANXA2 | annexin A2 | 0.0514216 |
| MAP1B | microtubule-associated protein 1B | 0.0507196 |
| ARRDC3 | arrestin domain containing 3 | 0.0492906 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0486759 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0480669 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0466608 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0457879 |
| ANXA5 | annexin A5 | 0.0443674 |
| NDRG1 | N-myc downstream regulated 1 | 0.0440434 |
| CD44 | CD44 molecule (Indian blood group) | 0.0436165 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0426847 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0420704 |
| VEGFA | vascular endothelial growth factor A | 0.0419752 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0418573 |
| CALU | calumenin | 0.0404206 |
| LOXL2 | lysyl oxidase-like 2 | 0.0396132 |
| ENO1 | enolase 1, (alpha) | 0.039473 |
| COL5A1 | collagen, type V, alpha 1 | 0.0389547 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0372204 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0370139 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0357577 |
| VEGFC | vascular endothelial growth factor C | 0.0352889 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.03465 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | 0.0343169 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0342625 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0341386 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0336687 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0336024 |
| NRXN3 | neurexin 3 | 0.0331431 |
| LDHA | lactate dehydrogenase A | 0.0328414 |
| PRSS23 | protease, serine, 23 | 0.0326686 |
| GOLGA4 | golgin A4 | 0.032588 |
| PRKCA | protein kinase C, alpha | 0.0319402 |
| LOX | lysyl oxidase | 0.0318848 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0315347 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.031142 |
| CANX | calnexin | 0.0303904 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | 0.0300951 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0299854 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0295707 |
| TNS3 | tensin 3 | 0.0295453 |
| LMAN1 | lectin, mannose-binding, 1 | 0.0291083 |
| PRELID2 | PRELI domain containing 2 | 0.028167 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0281611 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.028117 |
| HDLBP | high density lipoprotein binding protein | 0.0277469 |
| RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 | 0.027698 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0274704 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0274087 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0271291 |
| PGK1 | phosphoglycerate kinase 1 | 0.027045 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0268666 |
| UBC | ubiquitin C | 0.0265771 |
| PKM | pyruvate kinase, muscle | 0.0265268 |
| ANXA1 | annexin A1 | 0.026388 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.026231 |
| EGFR | epidermal growth factor receptor | 0.0261835 |
| NAV1 | neuron navigator 1 | 0.0257974 |
| HLA-C | major histocompatibility complex, class I, C | 0.0257859 |
| XPO1 | exportin 1 | 0.0253891 |
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | 0.0253431 |
| CALD1 | caldesmon 1 | 0.0252847 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0250166 |
| FMNL2 | formin-like 2 | 0.0248624 |
| PTGES2 | prostaglandin E synthase 2 | 0.0244901 |
| ADM | adrenomedullin | 0.0242067 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0241716 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0238945 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0238778 |
| ZNF395 | zinc finger protein 395 | 0.0237556 |
| SEPTIN9 | septin 9 | 0.0237375 |
| VCL | vinculin | 0.0232727 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | 0.0230239 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0226687 |
| CLTC | clathrin, heavy chain (Hc) | 0.0226218 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | 0.0224344 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.022384 |
| NBAS | neuroblastoma amplified sequence | 0.0223794 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0223072 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0221571 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0218762 |
| RRBP1 | ribosome binding protein 1 | 0.021787 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0217041 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | -0.0543292 |
| PTMA | prothymosin, alpha | -0.0276181 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0261103 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0245589 |
| RPL37A | ribosomal protein L37a | -0.0244271 |
| RPS3 | ribosomal protein S3 | -0.02229 |
| RPS17 | ribosomal protein S17 | -0.0222094 |
| RPL19 | ribosomal protein L19 | -0.0218223 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.021397 |
| RPL34 | ribosomal protein L34 | -0.0202292 |
| S100A6 | S100 calcium binding protein A6 | -0.0194136 |
| RPS5 | ribosomal protein S5 | -0.0169582 |
| RACK1 | receptor for activated C kinase 1 | -0.0166874 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0162625 |
| RPS13 | ribosomal protein S13 | -0.016208 |
| RPL26 | ribosomal protein L26 | -0.0160008 |
| RPS25 | ribosomal protein S25 | -0.0159976 |
| RPS12 | ribosomal protein S12 | -0.0159714 |
| RPL5 | ribosomal protein L5 | -0.0155408 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.0154273 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | -0.0147045 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0145575 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0142967 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0142843 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | -0.0141315 |
| CTR9 | CTR9, Paf1/RNA polymerase II complex component | -0.0141175 |
| GNAS | GNAS complex locus | -0.0138089 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0137926 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.013597 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.013483 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | -0.013465 |
| ZC3H15 | zinc finger CCCH-type containing 15 | -0.0132743 |
| RPLP2 | ribosomal protein, large, P2 | -0.0132516 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0130991 |
| CLU | clusterin | -0.0130563 |
| IER3 | immediate early response 3 | -0.0129697 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0129478 |
| KBTBD2 | kelch repeat and BTB (POZ) domain containing 2 | -0.0129095 |
| ZC3H13 | zinc finger CCCH-type containing 13 | -0.0128692 |
| UQCRQ | ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa | -0.0127702 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | -0.0126762 |
| RFX7 | regulatory factor X, 7 | -0.0126339 |
| NRG1 | neuregulin 1 | -0.0125966 |
| HPCAL1 | hippocalcin-like 1 | -0.0124567 |
| EGR1 | early growth response 1 | -0.0124391 |
| SIK3 | SIK family kinase 3 | -0.0124148 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0123158 |
| RPS29 | ribosomal protein S29 | -0.0122261 |
| RPL23 | ribosomal protein L23 | -0.0122253 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0122016 |
| RPS15 | ribosomal protein S15 | -0.012191 |
| OLA1 | Obg-like ATPase 1 | -0.0121803 |
| IRS2 | insulin receptor substrate 2 | -0.0121516 |
| RPL27A | ribosomal protein L27a | -0.0121384 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -0.0121333 |
| RPL35A | ribosomal protein L35a | -0.0120421 |
| WTAP | Wilms tumor 1 associated protein | -0.0119888 |
| PPP4R3A | protein phosphatase 4 regulatory subunit 3A | -0.0119266 |
| TMEM263 | transmembrane protein 263 | -0.0119126 |
| GALK2 | galactokinase 2 | -0.0118376 |
| LCOR | ligand dependent nuclear receptor corepressor | -0.0117984 |
| RPS10 | ribosomal protein S10 | -0.0117562 |
| SLMAP | sarcolemma associated protein | -0.0117541 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0116707 |
| FRMD5 | FERM domain containing 5 | -0.0116616 |
| RPL7A | ribosomal protein L7a | -0.0115871 |
| RPS27A | ribosomal protein S27a | -0.0115422 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.0115374 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | -0.0115297 |
| UVRAG | UV radiation resistance associated | -0.0115109 |
| SMG7 | SMG7 nonsense mediated mRNA decay factor | -0.0115002 |
| EXOC1 | exocyst complex component 1 | -0.0114776 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0112879 |
| EEF1D | eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) | -0.011196 |
| MPP2 | membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2) | -0.0111856 |
| SEC61B | Sec61 beta subunit | -0.0110711 |
| FAM168A | family with sequence similarity 168, member A | -0.0110433 |
| PDE10A | phosphodiesterase 10A | -0.0110376 |
| FLNB | filamin B, beta | -0.0110143 |
| ZNF652 | zinc finger protein 652 | -0.0110081 |
| BCL3 | B-cell CLL/lymphoma 3 | -0.0109885 |
| C2ORF42 | chromosome 2 open reading frame 42 | -0.0109806 |
| RPL37 | ribosomal protein L37 | -0.0109777 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0108693 |
| GPX4 | glutathione peroxidase 4 | -0.010821 |
| UBE2R2 | ubiquitin-conjugating enzyme E2R 2 | -0.0108071 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0107625 |
| RPL8 | ribosomal protein L8 | -0.0106846 |
| RPL10A | ribosomal protein L10a | -0.0106738 |
| INTS6L | integrator complex subunit 6 like | -0.0106718 |
| TIPRL | TOR signaling pathway regulator | -0.0106349 |
| FYN | FYN proto-oncogene, Src family tyrosine kinase | -0.0106168 |
| ATXN3 | ataxin 3 | -0.0105969 |
| BTN3A3 | butyrophilin, subfamily 3, member A3 | -0.0105757 |
| TENT4B | terminal nucleotidyltransferase 4B | -0.0105724 |
| CTSC | cathepsin C | -0.010532 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0105247 |
| KRT8 | keratin 8, type II | -0.0104918 |
| ZFHX3 | zinc finger homeobox 3 | -0.01042 |
| RBM6 | RNA binding motif protein 6 | -0.0104055 |
