Opiate Addiction Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description disease cluster belonging to disease group chemdependency (Genetic Association Database)
External Link https://www.disgenet.org/browser/0/1/0/C0524662
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Genes

78 genes associated with the disease Opiate Addiction in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ADCY1 adenylate cyclase 1 (brain)
ADGRV1 adhesion G protein-coupled receptor V1
ANKK1 ankyrin repeat and kinase domain containing 1
ARRB2 arrestin, beta 2
ATN1 atrophin 1
ATP2B2 ATPase, Ca++ transporting, plasma membrane 2
BDNF brain-derived neurotrophic factor
BMPER BMP binding endothelial regulator
C9 complement component 9
CARTPT CART prepropeptide
CD163 CD163 molecule
CD68 CD68 molecule
CES1 carboxylesterase 1
CHM choroideremia (Rab escort protein 1)
CNIH3 cornichon family AMPA receptor auxiliary protein 3
COMT catechol-O-methyltransferase
CRH corticotropin releasing hormone
CRY1 cryptochrome circadian clock 1
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
DBN1 drebrin 1
DISC1 disrupted in schizophrenia 1
DRD1 dopamine receptor D1
DRD2 dopamine receptor D2
DRD3 dopamine receptor D3
DRD4 dopamine receptor D4
DTNBP1 dystrobrevin binding protein 1
FKBP5 FK506 binding protein 5
GAL galanin/GMAP prepropeptide
GHRL ghrelin/obestatin prepropeptide
GRIA1 glutamate receptor, ionotropic, AMPA 1
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B
GRIN2D glutamate receptor, ionotropic, N-methyl D-aspartate 2D
GRK5 G protein-coupled receptor kinase 5
GRM6 glutamate receptor, metabotropic 6
GRM7 glutamate receptor, metabotropic 7
GRM8 glutamate receptor, metabotropic 8
HCRT hypocretin (orexin) neuropeptide precursor
HTR3A 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
INSRR insulin receptor-related receptor
KPNA3 karyopherin alpha 3 (importin alpha 4)
MAOA monoamine oxidase A
MAPK3 mitogen-activated protein kinase 3
MYD88 myeloid differentiation primary response 88
MYOCD myocardin
NAV3 neuron navigator 3
NGF nerve growth factor (beta polypeptide)
NISCH nischarin
NLN neurolysin (metallopeptidase M3 family)
NR4A2 nuclear receptor subfamily 4, group A, member 2
NRXN3 neurexin 3
OPN4 opsin 4
OPRD1 opioid receptor, delta 1
OPRK1 opioid receptor, kappa 1
OPRL1 opiate receptor-like 1
OPRM1 opioid receptor, mu 1
OR2AG1 olfactory receptor, family 2, subfamily AG, member 1 (gene/pseudogene)
PARP9 poly (ADP-ribose) polymerase family, member 9
PDYN prodynorphin
PENK proenkephalin
POMC proopiomelanocortin
PPP1R1B protein phosphatase 1, regulatory (inhibitor) subunit 1B
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme
RGMA repulsive guidance molecule family member a
SLC18A2 solute carrier family 18 (vesicular monoamine transporter), member 2
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
SNCA synuclein, alpha (non A4 component of amyloid precursor)
TCF4 transcription factor 4
TFF3 trefoil factor 3 (intestinal)
TPH1 tryptophan hydroxylase 1
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TTC9 tetratricopeptide repeat domain 9
VIPR2 vasoactive intestinal peptide receptor 2
ZNF565 zinc finger protein 565
ZNF699 zinc finger protein 699