Optic Neuropathy Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link https://www.disgenet.org/browser/0/1/0/C3887709
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Genes

53 genes associated with the disease Optic Neuropathy in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ACE angiotensin I converting enzyme
ACO2 aconitase 2, mitochondrial
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
APOE apolipoprotein E
AQP4 aquaporin 4
CASP3 caspase 3, apoptosis-related cysteine peptidase
CDK5 cyclin-dependent kinase 5
CRP C-reactive protein, pentraxin-related
DPYSL2 dihydropyrimidinase-like 2
EDN1 endothelin 1
EPO erythropoietin
ESR1 estrogen receptor 1
HMGB1 high mobility group box 1
KARS1 lysyl-tRNA synthetase 1
KIF1A kinesin family member 1A
KIF1B kinesin family member 1B
KNTC1 kinetochore associated 1
MAPK8 mitogen-activated protein kinase 8
MFN2 mitofusin 2
MMD monocyte to macrophage differentiation-associated
MOG myelin oligodendrocyte glycoprotein
MT-ATP8 ATP synthase F0 subunit 8
MT-ND4 NADH dehydrogenase, subunit 4 (complex I)
MT-ND6 NADH dehydrogenase, subunit 6 (complex I)
MYOC myocilin, trabecular meshwork inducible glucocorticoid response
NANOS2 nanos homolog 2 (Drosophila)
ND1
NDUFA1 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa
NDUFA13 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13
NOS2 nitric oxide synthase 2, inducible
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
OPA1 optic atrophy 1 (autosomal dominant)
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PGR progesterone receptor
PMP22 peripheral myelin protein 22
PRPS1 phosphoribosyl pyrophosphate synthetase 1
PTEN phosphatase and tensin homolog
RAG1 recombination activating gene 1
RTN4IP1 reticulon 4 interacting protein 1
SEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
SOD2 superoxide dismutase 2, mitochondrial
SSBP1 single-stranded DNA binding protein 1, mitochondrial
THY1 Thy-1 cell surface antigen
TLR9 toll-like receptor 9
TNF tumor necrosis factor
TP53 tumor protein p53
TSHR thyroid stimulating hormone receptor
TUB tubby bipartite transcription factor
TULP1 tubby like protein 1
USP7 ubiquitin specific peptidase 7 (herpes virus-associated)
WDHD1 WD repeat and HMG-box DNA binding protein 1
WFS1 Wolfram syndrome 1 (wolframin)