Orchitis Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores 2025
Category disease or phenotype associations
Type disease
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Genes

239 genes co-occuring with the disease Orchitis in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.

Symbol Name Standardized Value
ACE2 angiotensin I converting enzyme 2 2.617
TMPRSS2 transmembrane protease, serine 2 2.447
IL6 interleukin 6 2.186
CD4 CD4 molecule 2.13
SYNJ2BP synaptojanin 2 binding protein 2.068
TNF tumor necrosis factor 2.064
IFNG interferon, gamma 2.057
ZAN zonadhesin (gene/pseudogene) 2.046
IL1B interleukin 1, beta 2.025
CLDN11 claudin 11 2.006
AMH anti-Mullerian hormone 1.977
IL10 interleukin 10 1.958
CD68 CD68 molecule 1.954
CD8A CD8a molecule 1.927
CRP C-reactive protein, pentraxin-related 1.927
TEX11 testis expressed 11 1.89
CCL2 chemokine (C-C motif) ligand 2 1.867
PRL prolactin 1.823
PRM2 protamine 2 1.813
RNASE10 ribonuclease, RNase A family, 10 (non-active) 1.804
IL1A interleukin 1, alpha 1.784
PROKR1 prokineticin receptor 1 1.773
IL2 interleukin 2 1.753
SHBG sex hormone-binding globulin 1.745
DAZ1 deleted in azoospermia 1 1.743
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone) 1.735
IL17A interleukin 17A 1.723
AR androgen receptor 1.711
PROK2 prokineticin 2 1.707
FOXP3 forkhead box P3 1.702
TEX14 testis expressed 14 1.696
AFP alpha-fetoprotein 1.676
HSD3B1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 1.663
IL4 interleukin 4 1.644
OCLN occludin 1.641
ALB albumin 1.638
FASLG Fas ligand (TNF superfamily, member 6) 1.628
PRM1 protamine 1 1.621
BPY2 basic charge, Y-linked, 2 1.619
TLR4 toll-like receptor 4 1.619
GJB6 gap junction protein, beta 6, 30kDa 1.601
IFNA1 interferon, alpha 1 1.595
CXCL8 chemokine (C-X-C motif) ligand 8 1.585
MFSD6 major facilitator superfamily domain containing 6 1.583
DDX4 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 1.578
DAZ3 deleted in azoospermia 3 1.571
GTSF1L gametocyte specific factor 1-like 1.562
BSG basigin (Ok blood group) 1.554
CXCL10 chemokine (C-X-C motif) ligand 10 1.553
OR4F29 olfactory receptor, family 4, subfamily F, member 29 1.552
TLR2 toll-like receptor 2 1.551
KLK3 kallikrein-related peptidase 3 1.536
IFNAR1 interferon (alpha, beta and omega) receptor 1 1.536
TGFB1 transforming growth factor, beta 1 1.531
BPY2C basic charge, Y-linked, 2C 1.53
BPY2B basic charge, Y-linked, 2B 1.53
AIRE autoimmune regulator 1.529
IFNB1 interferon, beta 1, fibroblast 1.52
ACE angiotensin I converting enzyme 1.519
DAZ2 deleted in azoospermia 2 1.515
VWA7 von Willebrand factor A domain containing 7 1.503
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 1.501
STAR steroidogenic acute regulatory protein 1.499
INSL3 insulin-like 3 (Leydig cell) 1.494
CCL3 chemokine (C-C motif) ligand 3 1.482
GJA1 gap junction protein, alpha 1, 43kDa 1.481
ZMYND15 zinc finger, MYND-type containing 15 1.48
CRISP2 cysteine-rich secretory protein 2 1.476
ACTB actin, beta 1.476
PXDNL peroxidasin-like 1.475
PXDN peroxidasin 1.473
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1 1.472
TMPRSS11B transmembrane protease, serine 11B 1.47
CATSPER1 cation channel, sperm associated 1 1.468
MEIOB meiosis specific with OB domains 1.462
TNP1 transition protein 1 (during histone to protamine replacement) 1.459
REN renin 1.456
TMPRSS12 transmembrane (C-terminal) protease, serine 12 1.446
TEX15 testis expressed 15 1.441
CCER1 coiled-coil glutamate-rich protein 1 1.439
SHOC1 shortage in chiasmata 1 1.434
TLR3 toll-like receptor 3 1.433
DAZL deleted in azoospermia-like 1.432
FURIN furin (paired basic amino acid cleaving enzyme) 1.426
MEFV Mediterranean fever 1.42
SPAM1 sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding) 1.418
SEMG1 semenogelin I 1.417
CDY2A chromodomain protein, Y-linked, 2A 1.416
BRCA2 breast cancer 2, early onset 1.414
LDHC lactate dehydrogenase C 1.412
POMC proopiomelanocortin 1.412
IL18 interleukin 18 1.399
SRY sex determining region Y 1.396
EPPIN epididymal peptidase inhibitor 1.395
KIF21B kinesin family member 21B 1.394
SYCE1 synaptonemal complex central element protein 1 1.394
FSHB follicle stimulating hormone, beta polypeptide 1.389
IFNA2 interferon, alpha 2 1.387
GOLGA6L6 golgin A6 family-like 6 1.384
CTSL cathepsin L 1.369
CD86 CD86 molecule 1.362
TJP1 tight junction protein 1 1.36
TSSK6 testis-specific serine kinase 6 1.357
PTPRC protein tyrosine phosphatase, receptor type, C 1.352
CRISP1 cysteine-rich secretory protein 1 1.351
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit) 1.338
F2RL1 coagulation factor II (thrombin) receptor-like 1 1.335
HEATR9 HEAT repeat containing 9 1.329
SYCP3 synaptonemal complex protein 3 1.321
IL7 interleukin 7 1.32
TEKT2 tektin 2 (testicular) 1.319
FSHR follicle stimulating hormone receptor 1.318
CD80 CD80 molecule 1.312
PRTN3 proteinase 3 1.306
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) 1.304
AXL AXL receptor tyrosine kinase 1.302
CDY1 chromodomain protein, Y-linked, 1 1.3
C20ORF173 chromosome 20 open reading frame 173 1.299
AKAP4 A kinase (PRKA) anchor protein 4 1.298
CASP1 caspase 1, apoptosis-related cysteine peptidase 1.294
OR4F16 olfactory receptor, family 4, subfamily F, member 16 1.291
USP9Y ubiquitin specific peptidase 9, Y-linked 1.291
CYP11A1 cytochrome P450, family 11, subfamily A, polypeptide 1 1.289
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 1.287
REV1 REV1, polymerase (DNA directed) 1.284
GAPDH glyceraldehyde-3-phosphate dehydrogenase 1.274
STAG3 stromal antigen 3 1.268
CCR2 chemokine (C-C motif) receptor 2 1.265
CASP3 caspase 3, apoptosis-related cysteine peptidase 1.265
RASGEF1B RasGEF domain family, member 1B 1.263
TYRO3 TYRO3 protein tyrosine kinase 1.26
CD163 CD163 molecule 1.26
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1 1.26
GPT glutamic-pyruvate transaminase (alanine aminotransferase) 1.259
CBY1 chibby homolog 1 (Drosophila) 1.247
ACR acrosin 1.245
DNAH1 dynein, axonemal, heavy chain 1 1.244
GTPBP1 GTP binding protein 1 1.238
HSPA4L heat shock 70kDa protein 4-like 1.238
ESR1 estrogen receptor 1 1.231
ZFP30 ZFP30 zinc finger protein 1.222
TLR7 toll-like receptor 7 1.215
MYD88 myeloid differentiation primary response 88 1.215
LHCGR luteinizing hormone/choriogonadotropin receptor 1.212
INS insulin 1.207
ERVW-1 endogenous retrovirus group W, member 1 1.202
CD209 CD209 molecule 1.202
PHF7 PHD finger protein 7 1.2
NR5A1 nuclear receptor subfamily 5, group A, member 1 1.194
AKAP3 A kinase (PRKA) anchor protein 3 1.187
FHL5 four and a half LIM domains 5 1.185
RIMBP3 RIMS binding protein 3 1.183
TESK1 testis-specific kinase 1 1.183
IL22 interleukin 22 1.181
TNP2 transition protein 2 (during histone to protamine replacement) 1.18
IL13 interleukin 13 1.179
HOOK1 hook microtubule-tethering protein 1 1.178
GAPDHS glyceraldehyde-3-phosphate dehydrogenase, spermatogenic 1.177
FST follistatin 1.173
FSCN3 fascin actin-bundling protein 3, testicular 1.172
IDO1 indoleamine 2,3-dioxygenase 1 1.169
CCL4 chemokine (C-C motif) ligand 4 1.161
DEFB126 defensin, beta 126 1.159
DHRS11 dehydrogenase/reductase (SDR family) member 11 1.159
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked 1.157
DMRT1 doublesex and mab-3 related transcription factor 1 1.155
CCL5 chemokine (C-C motif) ligand 5 1.152
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 1.144
TPR translocated promoter region, nuclear basket protein 1.144
KIF1C kinesin family member 1C 1.143
NANOS2 nanos homolog 2 (Drosophila) 1.141
DNTT DNA nucleotidylexotransferase 1.14
ZNF32 zinc finger protein 32 1.14
ACTL7A actin-like 7A 1.14
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 1.138
IRF3 interferon regulatory factor 3 1.137
CATSPER4 cation channel, sperm associated 4 1.135
DRC7 dynein regulatory complex subunit 7 1.133
LGALS1 lectin, galactoside-binding, soluble, 1 1.132
CTLA4 cytotoxic T-lymphocyte-associated protein 4 1.13
NLRP3 NLR family, pyrin domain containing 3 1.125
BCL2 B-cell CLL/lymphoma 2 1.125
MX1 MX dynamin-like GTPase 1 1.121
ICAM1 intercellular adhesion molecule 1 1.119
TSSK3 testis-specific serine kinase 3 1.119
DPP4 dipeptidyl-peptidase 4 1.119
NACAD NAC alpha domain containing 1.117
DAZ4 deleted in azoospermia 4 1.116
CSF3 colony stimulating factor 3 (granulocyte) 1.114
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 1.113
VCAM1 vascular cell adhesion molecule 1 1.111
AGTR2 angiotensin II receptor, type 2 1.106
MPO myeloperoxidase 1.105
CASP8 caspase 8, apoptosis-related cysteine peptidase 1.098
UBQLN3 ubiquilin 3 1.097
UTF1 undifferentiated embryonic cell transcription factor 1 1.096
TDRD9 tudor domain containing 9 1.095
MRC1 mannose receptor, C type 1 1.094
SPATS1 spermatogenesis associated, serine-rich 1 1.093
CASR calcium-sensing receptor 1.092
IL5 interleukin 5 1.091
FAM47C family with sequence similarity 47, member C 1.091
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) 1.089
TLR1 toll-like receptor 1 1.088
MGARP mitochondria-localized glutamic acid-rich protein 1.088
HSD17B3 hydroxysteroid (17-beta) dehydrogenase 3 1.081
GSDMD gasdermin D 1.078
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog 1.076
HRH1 histamine receptor H1 1.07
ADM2 adrenomedullin 2 1.069
CABYR calcium binding tyrosine-(Y)-phosphorylation regulated 1.065
TMPRSS4 transmembrane protease, serine 4 1.063
ODF1 outer dense fiber of sperm tails 1 1.061
CFAP44 cilia and flagella associated protein 44 1.06
HRH4 histamine receptor H4 1.056
TSSK2 testis-specific serine kinase 2 1.051
CT47A4 cancer/testis antigen family 47, member A4 1.048
SPACA5B sperm acrosome associated 5B 1.047
GP2 glycoprotein 2 (zymogen granule membrane) 1.045
SEMG2 semenogelin II 1.043
STAT1 signal transducer and activator of transcription 1, 91kDa 1.039
IFIH1 interferon induced with helicase C domain 1 1.032
IL9 interleukin 9 1.032
CD274 CD274 molecule 1.029
SELL selectin L 1.024
SPATA16 spermatogenesis associated 16 1.024
TMCO2 transmembrane and coiled-coil domains 2 1.023
GDNF glial cell derived neurotrophic factor 1.022
TAF7L TAF7-like RNA polymerase II, TATA box binding protein (TBP)-associated factor, 50kDa 1.019
DEFB103B defensin, beta 103B 1.019
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa 1.015
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) 1.01
ZZZ3 zinc finger, ZZ-type containing 3 1.009
DNAH6 dynein, axonemal, heavy chain 6 1.008
SYCP1 synaptonemal complex protein 1 1.007
BRCA1 breast cancer 1, early onset 1.004
DHDH dihydrodiol dehydrogenase (dimeric) 1.003
TMCO5A transmembrane and coiled-coil domains 5A 1.001
ALPP alkaline phosphatase, placental 1.001