| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ornidazole perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Ornidazole_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TRIO | trio Rho guanine nucleotide exchange factor | 0.183934 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.143374 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0922367 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0915588 |
| FLNB | filamin B, beta | 0.0822292 |
| PODXL | podocalyxin-like | 0.0710147 |
| NAV2 | neuron navigator 2 | 0.0584351 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0504111 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0492675 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0476807 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0444385 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0414955 |
| RUNX1 | runt-related transcription factor 1 | 0.0412448 |
| PRELID2 | PRELI domain containing 2 | 0.0404963 |
| SLC22A23 | solute carrier family 22, member 23 | 0.0401207 |
| MYOF | myoferlin | 0.0388902 |
| PLAT | plasminogen activator, tissue | 0.0384338 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0383469 |
| NDRG1 | N-myc downstream regulated 1 | 0.0380566 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0360324 |
| NAV1 | neuron navigator 1 | 0.0360202 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0353696 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0349623 |
| OGA | O-GlcNAcase | 0.033053 |
| ZNF292 | zinc finger protein 292 | 0.0328135 |
| AGPAT5 | 1-acylglycerol-3-phosphate O-acyltransferase 5 | 0.0322025 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.03192 |
| ATP13A3 | ATPase type 13A3 | 0.0317394 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0311648 |
| SEPTIN9 | septin 9 | 0.0308292 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0296679 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | 0.0295236 |
| SBF2 | SET binding factor 2 | 0.0292916 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0287767 |
| TRAM2 | translocation associated membrane protein 2 | 0.028734 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0285554 |
| MT2A | metallothionein 2A | 0.0283398 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0274447 |
| GPC6 | glypican 6 | 0.0273644 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0271002 |
| YEATS2 | YEATS domain containing 2 | 0.0268934 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0267987 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0267306 |
| DENND1A | DENN/MADD domain containing 1A | 0.0262033 |
| AUTS2 | autism susceptibility candidate 2 | 0.026092 |
| APP | amyloid beta (A4) precursor protein | 0.0259346 |
| MED15 | mediator complex subunit 15 | 0.024883 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.024796 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0243407 |
| NBAS | neuroblastoma amplified sequence | 0.0240554 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0237055 |
| MB21D2 | Mab-21 domain containing 2 | 0.0231667 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | 0.0228606 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0228518 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0226781 |
| RASA3 | RAS p21 protein activator 3 | 0.0224878 |
| ABTB3 | ankyrin repeat and BTB domain containing 3 | 0.0214708 |
| DTNA | dystrobrevin, alpha | 0.0214108 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0212527 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0211943 |
| LENG8 | leukocyte receptor cluster (LRC) member 8 | 0.0205551 |
| DCAF6 | DDB1 and CUL4 associated factor 6 | 0.0204291 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0203913 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0203081 |
| SETD5 | SET domain containing 5 | 0.0200136 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0199416 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0197212 |
| SP3 | Sp3 transcription factor | 0.0196872 |
| SMYD3 | SET and MYND domain containing 3 | 0.0196374 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0195292 |
| STK10 | serine/threonine kinase 10 | 0.0194826 |
| VEGFA | vascular endothelial growth factor A | 0.0193319 |
| AFF3 | AF4/FMR2 family, member 3 | 0.0193309 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.019236 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0191394 |
| ANKRD10 | ankyrin repeat domain 10 | 0.0189167 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | 0.0186916 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0182772 |
| CD109 | CD109 molecule | 0.0181924 |
| CDK19 | cyclin-dependent kinase 19 | 0.0181822 |
| AMPD3 | adenosine monophosphate deaminase 3 | 0.0180284 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0178517 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.0177871 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.0176282 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0174778 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0172997 |
| ARFGEF3 | ARFGEF family member 3 | 0.0172971 |
| PRKD3 | protein kinase D3 | 0.0172904 |
| DCUN1D4 | DCN1, defective in cullin neddylation 1, domain containing 4 | 0.0172857 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.017243 |
| LOXL2 | lysyl oxidase-like 2 | 0.0172146 |
| INSIG2 | insulin induced gene 2 | 0.0171687 |
| ANO6 | anoctamin 6 | 0.017134 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0167035 |
| MEF2A | myocyte enhancer factor 2A | 0.0165914 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0165568 |
| CTTN | cortactin | 0.0165387 |
| FAM107B | family with sequence similarity 107, member B | 0.0164812 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | 0.0164622 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0164526 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.247786 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.23411 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.117371 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.117217 |
| MAP1B | microtubule-associated protein 1B | -0.103957 |
| LOX | lysyl oxidase | -0.100323 |
| TMSB10 | thymosin beta 10 | -0.0882173 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.083441 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0745306 |
| COL1A2 | collagen, type I, alpha 2 | -0.0717672 |
| AHNAK | AHNAK nucleoprotein | -0.0699372 |
| CSTB | cystatin B (stefin B) | -0.0663811 |
| S100A6 | S100 calcium binding protein A6 | -0.0659453 |
| HLA-C | major histocompatibility complex, class I, C | -0.0591904 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0584973 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0582693 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0572271 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.053041 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0498336 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0495204 |
| CALR | calreticulin | -0.046048 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0458957 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0431922 |
| HLA-A | major histocompatibility complex, class I, A | -0.0421294 |
| TPM4 | tropomyosin 4 | -0.0410622 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0402538 |
| MYADM | myeloid-associated differentiation marker | -0.0392577 |
| HLA-E | major histocompatibility complex, class I, E | -0.0391358 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0382569 |
| CANX | calnexin | -0.0368961 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0360501 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0360128 |
| COL3A1 | collagen, type III, alpha 1 | -0.035901 |
| FN1 | fibronectin 1 | -0.0354806 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.0352935 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0347046 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 | -0.033844 |
| SLC38A1 | solute carrier family 38, member 1 | -0.033235 |
| MEIS2 | Meis homeobox 2 | -0.0328013 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0323832 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0323106 |
| FTL | ferritin, light polypeptide | -0.0316371 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.031376 |
| PTMA | prothymosin, alpha | -0.0311169 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.0301083 |
| HLA-B | major histocompatibility complex, class I, B | -0.0295003 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0290834 |
| RRBP1 | ribosome binding protein 1 | -0.0286141 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0283365 |
| MX2 | MX dynamin-like GTPase 2 | -0.0281896 |
| BSG | basigin (Ok blood group) | -0.0281314 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0276212 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.027533 |
| CD99 | CD99 molecule | -0.0274262 |
| CCND1 | cyclin D1 | -0.0274033 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0268787 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0268346 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0265032 |
| COL5A2 | collagen, type V, alpha 2 | -0.0264455 |
| RIGI | RNA sensor RIG-I | -0.0261425 |
| SUCNR1 | succinate receptor 1 | -0.0258744 |
| SP100 | SP100 nuclear antigen | -0.0256294 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0255821 |
| HDLBP | high density lipoprotein binding protein | -0.0254305 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0253142 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0243469 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0242774 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0242532 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0242478 |
| IL7R | interleukin 7 receptor | -0.0237373 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0235646 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0233911 |
| L1CAM | L1 cell adhesion molecule | -0.0230852 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0224869 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0224619 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0223392 |
| TAGLN2 | transgelin 2 | -0.0222158 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0217202 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0212733 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.0211194 |
| S100A11 | S100 calcium binding protein A11 | -0.0207695 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0207297 |
| GOLGB1 | golgin B1 | -0.0199797 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | -0.0192653 |
| TUBB4B | tubulin, beta 4B class IVb | -0.01925 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0188332 |
| LMNA | lamin A/C | -0.0187576 |
| OASL | 2'-5'-oligoadenylate synthetase-like | -0.0186253 |
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) | -0.0183183 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0183022 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0182655 |
| RPS6 | ribosomal protein S6 | -0.0180719 |
| IGFBP6 | insulin-like growth factor binding protein 6 | -0.0177321 |
| RASAL2 | RAS protein activator like 2 | -0.0173354 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0172652 |
| POTEF | POTE ankyrin domain family, member F | -0.0170772 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0170726 |
| GNAS | GNAS complex locus | -0.016904 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0168391 |
| PFN1 | profilin 1 | -0.0167273 |
