| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ornidazole perturbation in A-427 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Ornidazole_A-427 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| YAP1 | Yes-associated protein 1 | 0.0742901 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0729969 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0713543 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0703539 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 0.0697452 |
| NHSL1 | NHS-like 1 | 0.0677771 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0647948 |
| HMGA2 | high mobility group AT-hook 2 | 0.0630558 |
| PDGFC | platelet derived growth factor C | 0.0561766 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0546336 |
| EHBP1 | EH domain binding protein 1 | 0.0523636 |
| ASPH | aspartate beta-hydroxylase | 0.05054 |
| MMP12 | matrix metallopeptidase 12 | 0.0497922 |
| TPM3 | tropomyosin 3 | 0.0487801 |
| NEBL | nebulette | 0.0485109 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0464854 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0437875 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0436228 |
| MED13L | mediator complex subunit 13-like | 0.0411238 |
| BCHE | butyrylcholinesterase | 0.0407938 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0395292 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0387626 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | 0.0366159 |
| SPATS2 | spermatogenesis associated, serine-rich 2 | 0.0350655 |
| TENM3 | teneurin transmembrane protein 3 | 0.0344126 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0339316 |
| VMP1 | vacuole membrane protein 1 | 0.0339127 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0338177 |
| MTAP | methylthioadenosine phosphorylase | 0.0329468 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0328338 |
| SMYD3 | SET and MYND domain containing 3 | 0.0326978 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.0325616 |
| YEATS2 | YEATS domain containing 2 | 0.0317804 |
| KCMF1 | potassium channel modulatory factor 1 | 0.0317188 |
| NR5A2 | nuclear receptor subfamily 5, group A, member 2 | 0.0311904 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | 0.0292066 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | 0.0291671 |
| DIP2B | DIP2 disco-interacting protein 2 homolog B (Drosophila) | 0.0290914 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0290062 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0286974 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0286941 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | 0.0285908 |
| NRXN3 | neurexin 3 | 0.0278846 |
| PRELID2 | PRELI domain containing 2 | 0.0273686 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0268704 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0266015 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0265926 |
| RPL3 | ribosomal protein L3 | 0.0265209 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0263653 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0262749 |
| NECTIN3 | nectin cell adhesion molecule 3 | 0.0257859 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0252174 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0247 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0246205 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) | 0.0245243 |
| VCL | vinculin | 0.0240786 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.0225021 |
| MTCL1 | microtubule crosslinking factor 1 | 0.0224473 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0224262 |
| FNIP1 | folliculin interacting protein 1 | 0.0220125 |
| JMJD1C | jumonji domain containing 1C | 0.021767 |
| NPC1 | Niemann-Pick disease, type C1 | 0.0216967 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0216558 |
| RAD51B | RAD51 paralog B | 0.0215975 |
| ATP2A2 | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 | 0.0213404 |
| FEZ2 | fasciculation and elongation protein zeta 2 (zygin II) | 0.0211092 |
| CLDND1 | claudin domain containing 1 | 0.0211073 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0206506 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0205856 |
| FHIT | fragile histidine triad | 0.0205262 |
| GSK3B | glycogen synthase kinase 3 beta | 0.020305 |
| KMT2D | lysine (K)-specific methyltransferase 2D | 0.0202247 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0200605 |
| NONO | non-POU domain containing, octamer-binding | 0.0198481 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0197116 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0196606 |
| ANK2 | ankyrin 2, neuronal | 0.0196011 |
| EXOC4 | exocyst complex component 4 | 0.0195036 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0194617 |
| ZNF407 | zinc finger protein 407 | 0.0194594 |
| CDK17 | cyclin-dependent kinase 17 | 0.0194368 |
| PRKCE | protein kinase C, epsilon | 0.0190046 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.019003 |
| AXIN2 | axin 2 | 0.0189517 |
| KSR2 | kinase suppressor of ras 2 | 0.0189011 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0187964 |
| RIMKLB | ribosomal modification protein rimK-like family member B | 0.0186309 |
| ATP2C1 | ATPase, Ca++ transporting, type 2C, member 1 | 0.018599 |
| RNF13 | ring finger protein 13 | 0.0184492 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.0184376 |
| EPHA6 | EPH receptor A6 | 0.0184289 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0184065 |
| RSF1 | remodeling and spacing factor 1 | 0.0183149 |
| RCOR1 | REST corepressor 1 | 0.0180388 |
| ZNF292 | zinc finger protein 292 | 0.0180112 |
| CCNG2 | cyclin G2 | 0.0179297 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0177841 |
| NAV3 | neuron navigator 3 | 0.0177163 |
| HHAT | hedgehog acyltransferase | 0.0176666 |
| KDM4B | lysine (K)-specific demethylase 4B | 0.0175555 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.27066 |
| AREG | amphiregulin | -0.169663 |
| TMSB10 | thymosin beta 10 | -0.151075 |
| FTL | ferritin, light polypeptide | -0.131852 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.126764 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.107912 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0926118 |
| RPS6 | ribosomal protein S6 | -0.0759863 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0724159 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0662616 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0640537 |
| PTMA | prothymosin, alpha | -0.0636223 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0606463 |
| RPLP1 | ribosomal protein, large, P1 | -0.0601338 |
| CCND1 | cyclin D1 | -0.0595638 |
| RPL35A | ribosomal protein L35a | -0.058397 |
| RPL12 | ribosomal protein L12 | -0.0561481 |
| CLDN1 | claudin 1 | -0.0529969 |
| RPL19 | ribosomal protein L19 | -0.0527013 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0520377 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0515122 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0512759 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0504445 |
| AHNAK | AHNAK nucleoprotein | -0.048929 |
| RPS24 | ribosomal protein S24 | -0.0463983 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0462894 |
| RPL8 | ribosomal protein L8 | -0.045025 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0446606 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0441659 |
| CELF2 | CUGBP, Elav-like family member 2 | -0.0438828 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -0.043365 |
| KIF5B | kinesin family member 5B | -0.0432514 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | -0.0432444 |
| CUBN | cubilin (intrinsic factor-cobalamin receptor) | -0.0428997 |
| RPS19 | ribosomal protein S19 | -0.0424455 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0420231 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0413036 |
| RPL11 | ribosomal protein L11 | -0.0408554 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.0408037 |
| GNAS | GNAS complex locus | -0.0400472 |
| PFN1 | profilin 1 | -0.0398826 |
| RPL34 | ribosomal protein L34 | -0.0393485 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0385866 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0385225 |
| YBX3 | Y box binding protein 3 | -0.0381743 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0359686 |
| RPL36 | ribosomal protein L36 | -0.0353983 |
| RPS8 | ribosomal protein S8 | -0.0353392 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | -0.0353073 |
| RPL23 | ribosomal protein L23 | -0.0352427 |
| LDHB | lactate dehydrogenase B | -0.0350496 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | -0.0339641 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0334672 |
| RPLP2 | ribosomal protein, large, P2 | -0.0332789 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0332439 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0332228 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0331847 |
| RPL26 | ribosomal protein L26 | -0.0322057 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | -0.0316911 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | -0.0313879 |
| YBX1 | Y box binding protein 1 | -0.031268 |
| RPS16 | ribosomal protein S16 | -0.0312388 |
| EDN1 | endothelin 1 | -0.0310401 |
| RPS2 | ribosomal protein S2 | -0.0309338 |
| RPL31 | ribosomal protein L31 | -0.0309301 |
| S100A6 | S100 calcium binding protein A6 | -0.030548 |
| RPL32 | ribosomal protein L32 | -0.0301938 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0298491 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0297974 |
| HLA-A | major histocompatibility complex, class I, A | -0.0296885 |
| CCT4 | chaperonin containing TCP1, subunit 4 (delta) | -0.0293664 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | -0.0291606 |
| RPS3 | ribosomal protein S3 | -0.0287812 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0287509 |
| GCG | glucagon | -0.0284813 |
| RPS4X | ribosomal protein S4, X-linked | -0.0284135 |
| RPL28 | ribosomal protein L28 | -0.0281303 |
| RPS14 | ribosomal protein S14 | -0.0278728 |
| TGM2 | transglutaminase 2 | -0.0274235 |
| RPS27A | ribosomal protein S27a | -0.0272525 |
| HMGA1 | high mobility group AT-hook 1 | -0.0271805 |
| ATP5F1E | ATP synthase F1 subunit epsilon | -0.0270864 |
| HDLBP | high density lipoprotein binding protein | -0.026968 |
| RPL27A | ribosomal protein L27a | -0.026678 |
| RPL13A | ribosomal protein L13a | -0.0265331 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.026482 |
| H1-0 | H1.0 linker histone | -0.0263351 |
| CXADR | coxsackie virus and adenovirus receptor | -0.026305 |
| RPS20 | ribosomal protein S20 | -0.0258196 |
| PTMS | parathymosin | -0.025498 |
| RPL7 | ribosomal protein L7 | -0.025364 |
| RPS5 | ribosomal protein S5 | -0.0252931 |
| NACA | nascent polypeptide-associated complex alpha subunit | -0.0251521 |
| TRMT112 | tRNA methyltransferase 11-2 homolog (S. cerevisiae) | -0.0251006 |
| RBM39 | RNA binding motif protein 39 | -0.0246794 |
| HMGB1 | high mobility group box 1 | -0.0245946 |
| SEC62 | SEC62 homolog (S. cerevisiae) | -0.024233 |
| PRKCI | protein kinase C, iota | -0.0241839 |
| EZR | ezrin | -0.0239081 |
| DHX36 | DEAH (Asp-Glu-Ala-His) box polypeptide 36 | -0.0237682 |
