| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ornidazole perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Ornidazole_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TXNIP | thioredoxin interacting protein | 0.102762 |
| NDRG1 | N-myc downstream regulated 1 | 0.100269 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0868525 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0804633 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0796085 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | 0.0769131 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0751504 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | 0.0715782 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | 0.0665314 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.0605404 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0598801 |
| RNF43 | ring finger protein 43 | 0.0587931 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0580195 |
| IFNGR1 | interferon gamma receptor 1 | 0.0578883 |
| PRELID2 | PRELI domain containing 2 | 0.0504143 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0502215 |
| RNF149 | ring finger protein 149 | 0.048683 |
| VEGFA | vascular endothelial growth factor A | 0.0465862 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | 0.0460294 |
| PTEN | phosphatase and tensin homolog | 0.0459688 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0454096 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.0442129 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0437682 |
| FNIP1 | folliculin interacting protein 1 | 0.0437079 |
| TMPRSS4 | transmembrane protease, serine 4 | 0.0434976 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0433035 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.043079 |
| RAPGEF1 | Rap guanine nucleotide exchange factor (GEF) 1 | 0.0418416 |
| SMAD3 | SMAD family member 3 | 0.0416575 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | 0.0412797 |
| MCTP2 | multiple C2 domains, transmembrane 2 | 0.0404075 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.0402587 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | 0.039585 |
| SORBS1 | sorbin and SH3 domain containing 1 | 0.0390637 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0380921 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0363872 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0363358 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0362905 |
| ATXN1 | ataxin 1 | 0.0362281 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0358542 |
| GRK3 | G protein-coupled receptor kinase 3 | 0.0357269 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0344374 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0343249 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0341906 |
| SBF2 | SET binding factor 2 | 0.0338355 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | 0.0327904 |
| USP3 | ubiquitin specific peptidase 3 | 0.0324163 |
| ARRDC3 | arrestin domain containing 3 | 0.0309629 |
| HELZ | helicase with zinc finger | 0.0308879 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0305757 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0303692 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0302007 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.030092 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.0297483 |
| CREB3L2 | cAMP responsive element binding protein 3-like 2 | 0.029521 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0293376 |
| ABHD2 | abhydrolase domain containing 2 | 0.0292828 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | 0.0289968 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0283684 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.028135 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0281 |
| HBS1L | HBS1-like translational GTPase | 0.0279403 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0276254 |
| NCOA3 | nuclear receptor coactivator 3 | 0.0274018 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0267889 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | 0.0267674 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0256943 |
| NCKAP5 | NCK-associated protein 5 | 0.02551 |
| CD46 | CD46 molecule, complement regulatory protein | 0.0253564 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0252541 |
| LDHA | lactate dehydrogenase A | 0.0250239 |
| YEATS2 | YEATS domain containing 2 | 0.0249455 |
| ZNF395 | zinc finger protein 395 | 0.0248729 |
| TBPL1 | TBP-like 1 | 0.0245979 |
| CLMN | calmin (calponin-like, transmembrane) | 0.0245441 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.024437 |
| RNF145 | ring finger protein 145 | 0.0244319 |
| TPCN1 | two pore segment channel 1 | 0.0242089 |
| EHF | ets homologous factor | 0.0241876 |
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 | 0.0237339 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | 0.0236864 |
| UBAC2 | UBA domain containing 2 | 0.023557 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | 0.023493 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0234727 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | 0.0234613 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | 0.02344 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0231095 |
| PDE8A | phosphodiesterase 8A | 0.0228759 |
| B2M | beta-2-microglobulin | 0.0227786 |
| RUNX1 | runt-related transcription factor 1 | 0.0227359 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0226577 |
| OGA | O-GlcNAcase | 0.0225785 |
| PADI1 | peptidyl arginine deiminase, type I | 0.0224337 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0224175 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0221971 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0218466 |
| ASPH | aspartate beta-hydroxylase | 0.0218388 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0218203 |
| SKAP2 | src kinase associated phosphoprotein 2 | 0.0217313 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0215818 |
| Symbol | Name | Standardized Value |
|---|---|---|
| RNF213 | ring finger protein 213 | -0.123646 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.11757 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.11381 |
| RIGI | RNA sensor RIG-I | -0.112382 |
| LYZ | lysozyme | -0.108823 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.104228 |
| MX1 | MX dynamin-like GTPase 1 | -0.102631 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0998364 |
| SQSTM1 | sequestosome 1 | -0.0996566 |
| ANXA2 | annexin A2 | -0.0931351 |
| LMO7 | LIM domain 7 | -0.0847785 |
| SP100 | SP100 nuclear antigen | -0.0825157 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.0802359 |
| MX2 | MX dynamin-like GTPase 2 | -0.0715338 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.070691 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0684318 |
| EGR1 | early growth response 1 | -0.0606728 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0586366 |
| STS | steroid sulfatase (microsomal), isozyme S | -0.0581867 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0562085 |
| HLA-E | major histocompatibility complex, class I, E | -0.0533658 |
| XAF1 | XIAP associated factor 1 | -0.0519361 |
| VCL | vinculin | -0.0512546 |
| HLA-C | major histocompatibility complex, class I, C | -0.0510682 |
| EZR | ezrin | -0.0499969 |
| EPHB2 | EPH receptor B2 | -0.0498175 |
| TJP1 | tight junction protein 1 | -0.0493437 |
| PTMA | prothymosin, alpha | -0.0488386 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0474823 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0464037 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0459748 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | -0.0459683 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0453564 |
| PERP | PERP, TP53 apoptosis effector | -0.0452206 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0433891 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0430768 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0416595 |
| PHF3 | PHD finger protein 3 | -0.0410575 |
| RRBP1 | ribosome binding protein 1 | -0.0409085 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0408313 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0406812 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | -0.0400363 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0399055 |
| C6ORF132 | chromosome 6 open reading frame 132 | -0.0395299 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | -0.038828 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | -0.038378 |
| ACTG1 | actin gamma 1 | -0.0383337 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0374856 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0373429 |
| NPSR1 | neuropeptide S receptor 1 | -0.035933 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | -0.0355714 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0351365 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0351153 |
| TSHZ2 | teashirt zinc finger homeobox 2 | -0.0346796 |
| PLSCR1 | phospholipid scramblase 1 | -0.0345973 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0344956 |
| JUN | jun proto-oncogene | -0.0329391 |
| MCL1 | myeloid cell leukemia 1 | -0.0327352 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0319826 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0319339 |
| PMP22 | peripheral myelin protein 22 | -0.0318628 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0318006 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | -0.0310596 |
| TMC5 | transmembrane channel-like 5 | -0.0308735 |
| PNPT1 | polyribonucleotide nucleotidyltransferase 1 | -0.0304982 |
| MUC13 | mucin 13, cell surface associated | -0.0299126 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0298334 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0296151 |
| ELOF1 | elongation factor 1 homolog (S. cerevisiae) | -0.0292583 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0289215 |
| LAP3 | leucine aminopeptidase 3 | -0.0285089 |
| IRF1 | interferon regulatory factor 1 | -0.0284408 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0284099 |
| IRS2 | insulin receptor substrate 2 | -0.0281452 |
| TFRC | transferrin receptor | -0.0281186 |
| HLA-A | major histocompatibility complex, class I, A | -0.0281133 |
| SPATA13 | spermatogenesis associated 13 | -0.0277857 |
| SDC4 | syndecan 4 | -0.0271894 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0264006 |
| MYO1E | myosin IE | -0.0261567 |
| OASL | 2'-5'-oligoadenylate synthetase-like | -0.0261172 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | -0.025751 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa | -0.025741 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | -0.0253378 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0252222 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | -0.0247645 |
| STAT2 | signal transducer and activator of transcription 2, 113kDa | -0.0246814 |
| ERBIN | erbb2 interacting protein | -0.0243998 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0241752 |
| INTS6 | integrator complex subunit 6 | -0.0241281 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0239124 |
| VPS37B | vacuolar protein sorting 37 homolog B (S. cerevisiae) | -0.0238617 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0238286 |
| GPX2 | glutathione peroxidase 2 | -0.0238103 |
| PLSCR2 | phospholipid scramblase 2 | -0.02381 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.023629 |
| ATF4 | activating transcription factor 4 | -0.023401 |
| MACC1 | metastasis associated in colon cancer 1 | -0.0233876 |
| CCND3 | cyclin D3 | -0.0232212 |
| HLA-B | major histocompatibility complex, class I, B | -0.023195 |
