| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ornidazole perturbation in Hs 766T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Ornidazole_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TRIO | trio Rho guanine nucleotide exchange factor | 0.153005 |
| MEF2A | myocyte enhancer factor 2A | 0.148823 |
| SULF1 | sulfatase 1 | 0.0952459 |
| FLNB | filamin B, beta | 0.092817 |
| PRELID2 | PRELI domain containing 2 | 0.0672764 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0570769 |
| MTSS1 | metastasis suppressor 1 | 0.0569972 |
| ADAMTS16 | ADAM metallopeptidase with thrombospondin type 1 motif, 16 | 0.0556062 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0535444 |
| MYOF | myoferlin | 0.0510014 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | 0.0459979 |
| FNIP1 | folliculin interacting protein 1 | 0.0429604 |
| KIAA1217 | KIAA1217 | 0.0426223 |
| ASPH | aspartate beta-hydroxylase | 0.0425131 |
| OGA | O-GlcNAcase | 0.0420555 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.042016 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0406355 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | 0.0396072 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0391621 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0390536 |
| SQLE | squalene epoxidase | 0.0380975 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0379703 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0376949 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0376543 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0365223 |
| PDGFB | platelet-derived growth factor beta polypeptide | 0.0364455 |
| SMAD3 | SMAD family member 3 | 0.0355813 |
| CUL4B | cullin 4B | 0.0350621 |
| SBF2 | SET binding factor 2 | 0.0349584 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0343909 |
| ZNF292 | zinc finger protein 292 | 0.033684 |
| AOPEP | aminopeptidase O (putative) | 0.0336366 |
| LNPEP | leucyl/cystinyl aminopeptidase | 0.0334237 |
| INTS6 | integrator complex subunit 6 | 0.0333781 |
| FOXO1 | forkhead box O1 | 0.032838 |
| RIN2 | Ras and Rab interactor 2 | 0.0321672 |
| ANLN | anillin, actin binding protein | 0.0318098 |
| STC1 | stanniocalcin 1 | 0.0311402 |
| HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 | 0.0306733 |
| RNF145 | ring finger protein 145 | 0.0306455 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.030389 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0296607 |
| ANKRD10 | ankyrin repeat domain 10 | 0.0292837 |
| SLMAP | sarcolemma associated protein | 0.0290233 |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) | 0.0288511 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0285155 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.028289 |
| NCOA3 | nuclear receptor coactivator 3 | 0.0278911 |
| CAPRIN2 | caprin family member 2 | 0.027862 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | 0.0278355 |
| NRCAM | neuronal cell adhesion molecule | 0.0272102 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0271384 |
| COG6 | component of oligomeric golgi complex 6 | 0.0270335 |
| CDC73 | cell division cycle 73 | 0.0269338 |
| SMYD3 | SET and MYND domain containing 3 | 0.0268503 |
| NRG1 | neuregulin 1 | 0.0267549 |
| ITGA6 | integrin, alpha 6 | 0.0265333 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0258909 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0257919 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.025766 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0257091 |
| RAI14 | retinoic acid induced 14 | 0.025562 |
| FLOT1 | flotillin 1 | 0.0254891 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0254425 |
| YAP1 | Yes-associated protein 1 | 0.0252637 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0251965 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0249636 |
| RPL4 | ribosomal protein L4 | 0.0249365 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0248264 |
| ASXL1 | additional sex combs like transcriptional regulator 1 | 0.0243909 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | 0.0243871 |
| TMEM135 | transmembrane protein 135 | 0.0243139 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0241628 |
| KDM1A | lysine (K)-specific demethylase 1A | 0.0239596 |
| NEK7 | NIMA-related kinase 7 | 0.0239503 |
| PIAS1 | protein inhibitor of activated STAT, 1 | 0.0238142 |
| SERINC3 | serine incorporator 3 | 0.0236043 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | 0.0235154 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0233329 |
| PTK2 | protein tyrosine kinase 2 | 0.0232927 |
| FOXO3 | forkhead box O3 | 0.0232872 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0231545 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | 0.0229673 |
| DIDO1 | death inducer-obliterator 1 | 0.0229359 |
| NF1 | neurofibromin 1 | 0.0227748 |
| METTL15 | methyltransferase like 15 | 0.0226722 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0225918 |
| EFNA5 | ephrin-A5 | 0.022264 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0222226 |
| ANKRD33B | ankyrin repeat domain 33B | 0.0221995 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0221983 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 | 0.0220049 |
| UHRF2 | ubiquitin-like with PHD and ring finger domains 2, E3 ubiquitin protein ligase | 0.0219635 |
| CDC27 | cell division cycle 27 | 0.0219177 |
| VCL | vinculin | 0.0218752 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0218301 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0217349 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0216639 |
| RNF19B | ring finger protein 19B | 0.0214558 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0214279 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NDRG1 | N-myc downstream regulated 1 | -0.20912 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.200593 |
| LOC112694756 | uncharaterized LOC112694756 | -0.107286 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.102619 |
| PLEC | plectin | -0.0980792 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0942371 |
| MT2A | metallothionein 2A | -0.09062 |
| IGF2 | insulin-like growth factor 2 | -0.0837922 |
| RPS6 | ribosomal protein S6 | -0.0827639 |
| POTEF | POTE ankyrin domain family, member F | -0.0827391 |
| CD44 | CD44 molecule (Indian blood group) | -0.0698197 |
| LMO7 | LIM domain 7 | -0.0578195 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0575012 |
| EZR | ezrin | -0.0555471 |
| TMSB10 | thymosin beta 10 | -0.0548515 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0491201 |
| GNAS | GNAS complex locus | -0.0486281 |
| FLNA | filamin A, alpha | -0.0470608 |
| TGM2 | transglutaminase 2 | -0.0469197 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0468152 |
| HLA-B | major histocompatibility complex, class I, B | -0.0455389 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0420731 |
| LAMA5 | laminin, alpha 5 | -0.040996 |
| B2M | beta-2-microglobulin | -0.0406738 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0397977 |
| ITGB4 | integrin, beta 4 | -0.0395414 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0385233 |
| RPL35A | ribosomal protein L35a | -0.0376666 |
| EGR1 | early growth response 1 | -0.037043 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0369788 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0353303 |
| TMSB4X | thymosin beta 4, X-linked | -0.0352793 |
| EFHD2 | EF-hand domain family, member D2 | -0.0351693 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0340189 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0340173 |
| PODXL | podocalyxin-like | -0.0321969 |
| RPS19 | ribosomal protein S19 | -0.0319012 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.03123 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.0310609 |
| TXNIP | thioredoxin interacting protein | -0.0309699 |
| FTL | ferritin, light polypeptide | -0.0307804 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | -0.0305078 |
| MT1X | metallothionein 1X | -0.0303699 |
| RPLP1 | ribosomal protein, large, P1 | -0.0303418 |
| VEGFA | vascular endothelial growth factor A | -0.0297512 |
| CYB5R3 | cytochrome b5 reductase 3 | -0.029706 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0296987 |
| RPL36 | ribosomal protein L36 | -0.0294643 |
| YBX1 | Y box binding protein 1 | -0.029088 |
| EMP1 | epithelial membrane protein 1 | -0.0286194 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0286183 |
| FSCN1 | fascin actin-bundling protein 1 | -0.0284974 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | -0.0284738 |
| IFI44L | interferon-induced protein 44-like | -0.0283908 |
| RPL12 | ribosomal protein L12 | -0.0283644 |
| RPL23 | ribosomal protein L23 | -0.0274012 |
| RPL8 | ribosomal protein L8 | -0.0270663 |
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) | -0.0268824 |
| S100A6 | S100 calcium binding protein A6 | -0.0268026 |
| LDHA | lactate dehydrogenase A | -0.0267186 |
| HELZ2 | helicase with zinc finger 2, transcriptional coactivator | -0.0265397 |
| RRBP1 | ribosome binding protein 1 | -0.0264883 |
| ANXA1 | annexin A1 | -0.0259807 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0259001 |
| RALGDS | ral guanine nucleotide dissociation stimulator | -0.0253909 |
| RIGI | RNA sensor RIG-I | -0.0252869 |
| MSN | moesin | -0.0250049 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0249841 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0248343 |
| HMGA1 | high mobility group AT-hook 1 | -0.0248154 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0247123 |
| RPS4X | ribosomal protein S4, X-linked | -0.024303 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0241848 |
| IGFBP6 | insulin-like growth factor binding protein 6 | -0.0241165 |
| S100A11 | S100 calcium binding protein A11 | -0.0236984 |
| S100A10 | S100 calcium binding protein A10 | -0.0232801 |
| KRT19 | keratin 19, type I | -0.023127 |
| ATP5F1E | ATP synthase F1 subunit epsilon | -0.0230932 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.023049 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0229792 |
| DHFR | dihydrofolate reductase | -0.0229576 |
| PCDH1 | protocadherin 1 | -0.022349 |
| NCOR2 | nuclear receptor corepressor 2 | -0.0218795 |
| CALB1 | calbindin 1, 28kDa | -0.0217546 |
| TINAGL1 | tubulointerstitial nephritis antigen-like 1 | -0.0216108 |
| HLA-C | major histocompatibility complex, class I, C | -0.0215166 |
| RPLP2 | ribosomal protein, large, P2 | -0.0214471 |
| ANO1 | anoctamin 1, calcium activated chloride channel | -0.0213716 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0213709 |
| FN1 | fibronectin 1 | -0.0210414 |
| GOLGB1 | golgin B1 | -0.0210124 |
| EPHA2 | EPH receptor A2 | -0.0209476 |
| RPL36A | ribosomal protein L36a | -0.0207877 |
| ATF4 | activating transcription factor 4 | -0.0207194 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0206735 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0206724 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.0206444 |
| RPL34 | ribosomal protein L34 | -0.0205672 |
| MXRA5 | matrix-remodelling associated 5 | -0.0205501 |
| CSNK1E | casein kinase 1, epsilon | -0.020411 |
