| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ornidazole perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Ornidazole_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0823075 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0751241 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0685917 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0624915 |
| DST | dystonin | 0.0577224 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0473544 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0406593 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0402992 |
| LOXL2 | lysyl oxidase-like 2 | 0.040166 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0362052 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0358442 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0356401 |
| RUNX1 | runt-related transcription factor 1 | 0.0350252 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0348933 |
| EHBP1 | EH domain binding protein 1 | 0.0347435 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0311868 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | 0.0310585 |
| EFNA5 | ephrin-A5 | 0.0306693 |
| YEATS2 | YEATS domain containing 2 | 0.0301462 |
| DOCK11 | dedicator of cytokinesis 11 | 0.0297269 |
| FNIP1 | folliculin interacting protein 1 | 0.029489 |
| TP63 | tumor protein p63 | 0.02927 |
| TNS3 | tensin 3 | 0.0287821 |
| RAD51B | RAD51 paralog B | 0.0287299 |
| DENND1A | DENN/MADD domain containing 1A | 0.0284363 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.028427 |
| PDE10A | phosphodiesterase 10A | 0.0276412 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0265833 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0257932 |
| PODXL | podocalyxin-like | 0.0244035 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0242611 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0241244 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0228126 |
| CAPRIN2 | caprin family member 2 | 0.0226111 |
| PRELID2 | PRELI domain containing 2 | 0.0223631 |
| SMAD3 | SMAD family member 3 | 0.02235 |
| PLEC | plectin | 0.0222232 |
| FMNL2 | formin-like 2 | 0.0215613 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.021531 |
| EXOC4 | exocyst complex component 4 | 0.0214563 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0210771 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0206418 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0203059 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.019825 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | 0.0196093 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0194166 |
| UBE2E3 | ubiquitin-conjugating enzyme E2E 3 | 0.0192632 |
| MYOF | myoferlin | 0.0189483 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.0189226 |
| PYGL | phosphorylase, glycogen, liver | 0.0188571 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0188504 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0188274 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0187526 |
| SMYD3 | SET and MYND domain containing 3 | 0.0187282 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0187169 |
| HPCAL1 | hippocalcin-like 1 | 0.0184171 |
| CADM2 | cell adhesion molecule 2 | 0.0182785 |
| MTCL1 | microtubule crosslinking factor 1 | 0.0181973 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0179952 |
| KDM4B | lysine (K)-specific demethylase 4B | 0.0179501 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0177721 |
| CFAP299 | cilia and flagella associated protein 299 | 0.0177626 |
| HDAC9 | histone deacetylase 9 | 0.0176933 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 | 0.0175757 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | 0.017421 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0172223 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0168954 |
| CSMD3 | CUB and Sushi multiple domains 3 | 0.0168378 |
| ZNF292 | zinc finger protein 292 | 0.0168314 |
| PRRC2B | proline-rich coiled-coil 2B | 0.0167824 |
| EPHA4 | EPH receptor A4 | 0.0163874 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0161796 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0160743 |
| CDK19 | cyclin-dependent kinase 19 | 0.0160525 |
| EGFR | epidermal growth factor receptor | 0.0158817 |
| DPYSL2 | dihydropyrimidinase-like 2 | 0.0158044 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.01507 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0149476 |
| MED15 | mediator complex subunit 15 | 0.0144475 |
| PATJ | PATJ crumbs cell polarity complex component | 0.014406 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0142588 |
| BEGAIN | brain-enriched guanylate kinase-associated | 0.014146 |
| PPFIA4 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 | 0.0141191 |
| CEP250 | centrosomal protein 250kDa | 0.0140534 |
| MEF2A | myocyte enhancer factor 2A | 0.0137221 |
| TTC28 | tetratricopeptide repeat domain 28 | 0.0136565 |
| LRRC49 | leucine rich repeat containing 49 | 0.0134631 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0134466 |
| DPYD | dihydropyrimidine dehydrogenase | 0.013316 |
| VEGFC | vascular endothelial growth factor C | 0.0132508 |
| PTK2 | protein tyrosine kinase 2 | 0.0131353 |
| UBAP2L | ubiquitin associated protein 2-like | 0.0131307 |
| MNMIP1 | manchette microtubule inner protein 1 | 0.0131024 |
| GYS1 | glycogen synthase 1 (muscle) | 0.0131023 |
| GNGT1 | guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 | 0.0130795 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0128534 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | 0.0128146 |
| DNER | delta/notch-like EGF repeat containing | 0.0127044 |
| MYO18A | myosin XVIIIA | 0.0126355 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0125679 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.459287 |
| VIM | vimentin | -0.396447 |
| MT2A | metallothionein 2A | -0.182878 |
| PTMA | prothymosin, alpha | -0.154305 |
| TMSB10 | thymosin beta 10 | -0.153351 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.140472 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.123052 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.108342 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.104777 |
| FTL | ferritin, light polypeptide | -0.0911393 |
| UBC | ubiquitin C | -0.0892239 |
| RPS6 | ribosomal protein S6 | -0.0664276 |
| LDHA | lactate dehydrogenase A | -0.0643476 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0632626 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0603628 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0588825 |
| POTEF | POTE ankyrin domain family, member F | -0.0569448 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0553186 |
| RPL12 | ribosomal protein L12 | -0.0533082 |
| ENO1 | enolase 1, (alpha) | -0.0527637 |
| HMGA1 | high mobility group AT-hook 1 | -0.0524582 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0506933 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0500632 |
| RPS8 | ribosomal protein S8 | -0.0490885 |
| RPL35A | ribosomal protein L35a | -0.0490207 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0477081 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0449738 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0439913 |
| RPS27A | ribosomal protein S27a | -0.0430826 |
| RPL23 | ribosomal protein L23 | -0.0423379 |
| MT1X | metallothionein 1X | -0.0414197 |
| TXNIP | thioredoxin interacting protein | -0.040995 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0404102 |
| PCBP2 | poly(rC) binding protein 2 | -0.0391884 |
| RPLP2 | ribosomal protein, large, P2 | -0.0390149 |
| ACTG1 | actin gamma 1 | -0.0387613 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0375419 |
| MT1E | metallothionein 1E | -0.0372739 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0371156 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0357091 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0356241 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0348492 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0345705 |
| CALR | calreticulin | -0.034566 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0345535 |
| AHNAK | AHNAK nucleoprotein | -0.0340275 |
| RPLP1 | ribosomal protein, large, P1 | -0.0336867 |
| RPS19 | ribosomal protein S19 | -0.0328875 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0325936 |
| JUN | jun proto-oncogene | -0.0325505 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0322719 |
| SRGN | serglycin | -0.0320246 |
| S100A6 | S100 calcium binding protein A6 | -0.0319559 |
| SEPTIN7 | septin 7 | -0.0319416 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0314846 |
| RPL19 | ribosomal protein L19 | -0.0309452 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0309177 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0308977 |
| RPL5 | ribosomal protein L5 | -0.0301158 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0300649 |
| CANX | calnexin | -0.0297884 |
| RPL31 | ribosomal protein L31 | -0.029609 |
| RPS3 | ribosomal protein S3 | -0.0294718 |
| RPL8 | ribosomal protein L8 | -0.0290959 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0290684 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0287665 |
| RPL28 | ribosomal protein L28 | -0.02829 |
| RPS23 | ribosomal protein S23 | -0.0280686 |
| RPL26 | ribosomal protein L26 | -0.0280517 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0279316 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0273174 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | -0.027225 |
| TPI1 | triosephosphate isomerase 1 | -0.0271727 |
| RPS24 | ribosomal protein S24 | -0.0267843 |
| YBX1 | Y box binding protein 1 | -0.0266127 |
| RPL36 | ribosomal protein L36 | -0.026319 |
| PFN1 | profilin 1 | -0.0262739 |
| TNFRSF6B | tumor necrosis factor receptor superfamily, member 6b, decoy | -0.0260684 |
| RPS12 | ribosomal protein S12 | -0.0256087 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0253491 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | -0.0252464 |
| B2M | beta-2-microglobulin | -0.0246786 |
| PKM | pyruvate kinase, muscle | -0.0244651 |
| RPS14 | ribosomal protein S14 | -0.0243135 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.023764 |
| S100A9 | S100 calcium binding protein A9 | -0.0237525 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0237444 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0236435 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0231614 |
| HLA-B | major histocompatibility complex, class I, B | -0.0229866 |
| WDR45B | WD repeat domain 45B | -0.0227674 |
| RPS13 | ribosomal protein S13 | -0.0227658 |
| S100A10 | S100 calcium binding protein A10 | -0.0221546 |
| RPS25 | ribosomal protein S25 | -0.022062 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0217654 |
| RPL35 | ribosomal protein L35 | -0.0214437 |
| RPS5 | ribosomal protein S5 | -0.0213139 |
| RBM25 | RNA binding motif protein 25 | -0.0213096 |
| RPL36A | ribosomal protein L36a | -0.0212442 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0211323 |
