| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ornidazole perturbation in NCI-H1573 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Ornidazole_NCI-H1573 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EGFR | epidermal growth factor receptor | 0.104979 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0964253 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0656839 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0637374 |
| ANKRD10 | ankyrin repeat domain 10 | 0.0576971 |
| TOP1 | topoisomerase (DNA) I | 0.0547135 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0546836 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0546337 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | 0.0536797 |
| RNF145 | ring finger protein 145 | 0.0535545 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0529552 |
| SMAD3 | SMAD family member 3 | 0.0524479 |
| LAMC2 | laminin, gamma 2 | 0.047655 |
| RUNX1 | runt-related transcription factor 1 | 0.0469784 |
| FAM13A | family with sequence similarity 13, member A | 0.0428283 |
| NCOA3 | nuclear receptor coactivator 3 | 0.0387293 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | 0.038109 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0360631 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0349992 |
| AP1S3 | adaptor-related protein complex 1, sigma 3 subunit | 0.0343651 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.03426 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0335386 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.0333215 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0309399 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | 0.0301309 |
| ATP13A3 | ATPase type 13A3 | 0.0295891 |
| KCMF1 | potassium channel modulatory factor 1 | 0.0291633 |
| AGO2 | argonaute RISC catalytic component 2 | 0.0288594 |
| RPL4 | ribosomal protein L4 | 0.0285185 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0284304 |
| GPAT3 | glycerol-3-phosphate acyltransferase 3 | 0.0277497 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0276726 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0274997 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0273119 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0273094 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0264965 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0257704 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0256475 |
| EFNA5 | ephrin-A5 | 0.0254197 |
| RPS3 | ribosomal protein S3 | 0.0253844 |
| SLTM | SAFB-like, transcription modulator | 0.0249542 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0246651 |
| SLMAP | sarcolemma associated protein | 0.0245105 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | 0.0243215 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | 0.0242394 |
| DTNA | dystrobrevin, alpha | 0.0242268 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0239053 |
| HELZ | helicase with zinc finger | 0.023822 |
| RPL3 | ribosomal protein L3 | 0.0237986 |
| ENSA | endosulfine alpha | 0.0237087 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0234428 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0233142 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0231054 |
| RNF149 | ring finger protein 149 | 0.0230872 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0229388 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0224645 |
| TNFAIP8 | tumor necrosis factor, alpha-induced protein 8 | 0.0224194 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0222391 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0220872 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.021897 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0218605 |
| RAP1B | RAP1B, member of RAS oncogene family | 0.0215332 |
| EP300 | E1A binding protein p300 | 0.0213677 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0213642 |
| ZNF292 | zinc finger protein 292 | 0.0213214 |
| RASA2 | RAS p21 protein activator 2 | 0.0211469 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0209833 |
| B3GNT5 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5 | 0.0209168 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0207961 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | 0.0206221 |
| RTN4 | reticulon 4 | 0.0205946 |
| MT2A | metallothionein 2A | 0.0205142 |
| MCL1 | myeloid cell leukemia 1 | 0.0204597 |
| SLC35F5 | solute carrier family 35, member F5 | 0.0203635 |
| ZFAND6 | zinc finger, AN1-type domain 6 | 0.0202558 |
| YAP1 | Yes-associated protein 1 | 0.0202281 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | 0.0200112 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.0196664 |
| FNIP1 | folliculin interacting protein 1 | 0.0196199 |
| MKI67 | marker of proliferation Ki-67 | 0.0195747 |
| MLKL | mixed lineage kinase domain-like | 0.0192557 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0189188 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.018874 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0183819 |
| DOCK5 | dedicator of cytokinesis 5 | 0.018268 |
| MED13L | mediator complex subunit 13-like | 0.0181852 |
| LAMB3 | laminin, beta 3 | 0.0176245 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.0175947 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0175656 |
| NDUFV2 | NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa | 0.0175653 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0175599 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0174517 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0173063 |
| ATP11A | ATPase, class VI, type 11A | 0.0172539 |
| TENT2 | terminal nucleotidyltransferase 2 | 0.0170855 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.016935 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0168102 |
| NPC1 | Niemann-Pick disease, type C1 | 0.01663 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.0165704 |
| KIAA1217 | KIAA1217 | 0.0165602 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.262792 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.250612 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.186414 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0945103 |
| TMSB10 | thymosin beta 10 | -0.0861103 |
| NDRG1 | N-myc downstream regulated 1 | -0.0792314 |
| PTMA | prothymosin, alpha | -0.0669794 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0646307 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0644427 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.060429 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0575824 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0571891 |
| CES1 | carboxylesterase 1 | -0.0553312 |
| HDLBP | high density lipoprotein binding protein | -0.0549 |
| H1-0 | H1.0 linker histone | -0.0537413 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0535519 |
| LMO7 | LIM domain 7 | -0.052454 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0510254 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0504217 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0492924 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0485374 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0475727 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0462839 |
| KRT18 | keratin 18, type I | -0.0460356 |
| AHNAK | AHNAK nucleoprotein | -0.0455837 |
| S100A10 | S100 calcium binding protein A10 | -0.0426617 |
| FTL | ferritin, light polypeptide | -0.0426273 |
| TXNRD1 | thioredoxin reductase 1 | -0.0423219 |
| EGR1 | early growth response 1 | -0.0417904 |
| CANX | calnexin | -0.0416228 |
| LDHA | lactate dehydrogenase A | -0.0400242 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0398506 |
| ACTG1 | actin gamma 1 | -0.0391086 |
| PKM | pyruvate kinase, muscle | -0.0368301 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0365156 |
| GOLGB1 | golgin B1 | -0.0360197 |
| F11R | F11 receptor | -0.0353511 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0347856 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0334436 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0322553 |
| HMGA1 | high mobility group AT-hook 1 | -0.0313459 |
| RNF213 | ring finger protein 213 | -0.0312864 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0312313 |
| EMP1 | epithelial membrane protein 1 | -0.0310254 |
| HYOU1 | hypoxia up-regulated 1 | -0.0292373 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0291181 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0289848 |
| CST3 | cystatin C | -0.0286672 |
| ASPH | aspartate beta-hydroxylase | -0.0283376 |
| EZR | ezrin | -0.0282106 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0277278 |
| AGR2 | anterior gradient 2 | -0.0275805 |
| S100A6 | S100 calcium binding protein A6 | -0.0272215 |
| MORF4L2 | mortality factor 4 like 2 | -0.0255174 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0252096 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0250046 |
| RPL35A | ribosomal protein L35a | -0.024686 |
| CCND1 | cyclin D1 | -0.024658 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0243958 |
| ENO1 | enolase 1, (alpha) | -0.0242257 |
| STC1 | stanniocalcin 1 | -0.024189 |
| DSPP | dentin sialophosphoprotein | -0.02398 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.023873 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0235954 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.023226 |
| CALR | calreticulin | -0.0231513 |
| CPE | carboxypeptidase E | -0.0231432 |
| RPS6 | ribosomal protein S6 | -0.0230351 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | -0.0226751 |
| POTEF | POTE ankyrin domain family, member F | -0.0225014 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0219925 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0213892 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0213817 |
| HLA-B | major histocompatibility complex, class I, B | -0.0212002 |
| ARCN1 | archain 1 | -0.0211508 |
| HLA-A | major histocompatibility complex, class I, A | -0.0211062 |
| HM13 | histocompatibility (minor) 13 | -0.0210584 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0208259 |
| PERP | PERP, TP53 apoptosis effector | -0.0205877 |
| GNAS | GNAS complex locus | -0.0205585 |
| GOLGA4 | golgin A4 | -0.0205221 |
| TES | testin LIM domain protein | -0.0203592 |
| CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase | -0.0200961 |
| SRPRA | SRP receptor subunit alpha | -0.0200731 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0199137 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0198881 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0197056 |
| MYOF | myoferlin | -0.0195364 |
| ANXA2 | annexin A2 | -0.0191272 |
| DHFR | dihydrofolate reductase | -0.0190627 |
| RIOK3 | RIO kinase 3 | -0.018621 |
| TMF1 | TATA element modulatory factor 1 | -0.0186028 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0185856 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0185368 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0181367 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0180164 |
| KMT2A | lysine (K)-specific methyltransferase 2A | -0.0179416 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0178753 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0178256 |
| CSDE1 | cold shock domain containing E1, RNA-binding | -0.01768 |
