| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ornidazole perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Ornidazole_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NAMPT | nicotinamide phosphoribosyltransferase | 0.135988 |
| FAM13A | family with sequence similarity 13, member A | 0.135866 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0696011 |
| GOLGA4 | golgin A4 | 0.0623336 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0612183 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0597791 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0571464 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0545928 |
| HELZ | helicase with zinc finger | 0.0542984 |
| PRELID2 | PRELI domain containing 2 | 0.0522406 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0516958 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0505593 |
| NGLY1 | N-glycanase 1 | 0.0496998 |
| ZNF292 | zinc finger protein 292 | 0.0493301 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0488041 |
| FBXL13 | F-box and leucine-rich repeat protein 13 | 0.0472506 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0449196 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0445558 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0407425 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0384759 |
| RNF145 | ring finger protein 145 | 0.0383969 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0382694 |
| SETD5 | SET domain containing 5 | 0.0380717 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0375612 |
| COG5 | component of oligomeric golgi complex 5 | 0.0374888 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0357823 |
| USP3 | ubiquitin specific peptidase 3 | 0.0357593 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | 0.0355546 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0351417 |
| LRRC49 | leucine rich repeat containing 49 | 0.0342471 |
| GPC6 | glypican 6 | 0.0340368 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0337844 |
| OGA | O-GlcNAcase | 0.0337743 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0330012 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | 0.0329509 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0322542 |
| SBF2 | SET binding factor 2 | 0.0321364 |
| SMAD3 | SMAD family member 3 | 0.031545 |
| PIAS2 | protein inhibitor of activated STAT, 2 | 0.0304426 |
| AP3S1 | adaptor-related protein complex 3, sigma 1 subunit | 0.0302914 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0293106 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0282817 |
| CD109 | CD109 molecule | 0.0276045 |
| RUNX2 | runt-related transcription factor 2 | 0.0275646 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0274738 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.027317 |
| NBAS | neuroblastoma amplified sequence | 0.0271933 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0271528 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0271016 |
| VEGFA | vascular endothelial growth factor A | 0.0268979 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0264145 |
| PHF21A | PHD finger protein 21A | 0.0264046 |
| USP34 | ubiquitin specific peptidase 34 | 0.0260548 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0258997 |
| YEATS2 | YEATS domain containing 2 | 0.0258901 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0256426 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0254715 |
| RUNX1 | runt-related transcription factor 1 | 0.0250446 |
| MYOF | myoferlin | 0.0250295 |
| PARP8 | poly (ADP-ribose) polymerase family, member 8 | 0.0248056 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0247666 |
| SRP54 | signal recognition particle 54kDa | 0.0247388 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0246942 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | 0.0242987 |
| MXI1 | MAX interactor 1, dimerization protein | 0.024292 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0241626 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | 0.023585 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.023578 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0235003 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0234581 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | 0.0232088 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0231037 |
| COPA | coatomer protein complex, subunit alpha | 0.0230745 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0229589 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0228827 |
| ZNRF1 | zinc and ring finger 1, E3 ubiquitin protein ligase | 0.0227904 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0224032 |
| CDC73 | cell division cycle 73 | 0.0223981 |
| C1GALT1 | core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 | 0.0223342 |
| ANKRD11 | ankyrin repeat domain 11 | 0.022264 |
| SUCO | SUN domain containing ossification factor | 0.022233 |
| TPD52 | tumor protein D52 | 0.0222312 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0218705 |
| USP37 | ubiquitin specific peptidase 37 | 0.021657 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0214955 |
| FBXO42 | F-box protein 42 | 0.0214519 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0214017 |
| OTUD7B | OTU deubiquitinase 7B | 0.0212767 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0211564 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0210825 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.0207101 |
| QKI | QKI, KH domain containing, RNA binding | 0.0205969 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.0205482 |
| ESCO1 | establishment of sister chromatid cohesion N-acetyltransferase 1 | 0.020528 |
| SLC44A1 | solute carrier family 44 (choline transporter), member 1 | 0.0204438 |
| ATP13A3 | ATPase type 13A3 | 0.0204391 |
| RIOK3 | RIO kinase 3 | 0.0204223 |
| SLTM | SAFB-like, transcription modulator | 0.020211 |
| AAK1 | AP2 associated kinase 1 | 0.0201772 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0200035 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.24099 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.172139 |
| CD44 | CD44 molecule (Indian blood group) | -0.155595 |
| PCBP2 | poly(rC) binding protein 2 | -0.150312 |
| TMSB10 | thymosin beta 10 | -0.144118 |
| UBC | ubiquitin C | -0.0981896 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0910961 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0898568 |
| LOX | lysyl oxidase | -0.0838131 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | -0.0826496 |
| FN1 | fibronectin 1 | -0.0787095 |
| GLCCI1 | glucocorticoid induced 1 | -0.0742621 |
| NRG1 | neuregulin 1 | -0.071615 |
| MT2A | metallothionein 2A | -0.0709439 |
| ENO1 | enolase 1, (alpha) | -0.0672168 |
| AHNAK | AHNAK nucleoprotein | -0.0655138 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0647773 |
| CDH13 | cadherin 13 | -0.063624 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0630811 |
| MTSS1 | metastasis suppressor 1 | -0.0575301 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0531107 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0529037 |
| STC1 | stanniocalcin 1 | -0.0528033 |
| PTMA | prothymosin, alpha | -0.0496986 |
| RPL23 | ribosomal protein L23 | -0.0486991 |
| RPLP1 | ribosomal protein, large, P1 | -0.0486775 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0480263 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0476113 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0464206 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0453935 |
| FTL | ferritin, light polypeptide | -0.0453126 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0451919 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0441743 |
| PKM | pyruvate kinase, muscle | -0.0440188 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0429241 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0426245 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0418346 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | -0.0404866 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0391538 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0384462 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0377029 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0373278 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0373124 |
| NTN4 | netrin 4 | -0.0373022 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.036732 |
| LDHA | lactate dehydrogenase A | -0.0366868 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0365504 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.036409 |
| JUN | jun proto-oncogene | -0.0361165 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0357117 |
| FBN1 | fibrillin 1 | -0.0354762 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0354159 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.034962 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0336352 |
| FAM20C | family with sequence similarity 20, member C | -0.0335678 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0335444 |
| POTEF | POTE ankyrin domain family, member F | -0.032805 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0323146 |
| RPS19 | ribosomal protein S19 | -0.0322872 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0321991 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.032074 |
| B2M | beta-2-microglobulin | -0.0320583 |
| RPLP2 | ribosomal protein, large, P2 | -0.0312132 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0311901 |
| ANKRD28 | ankyrin repeat domain 28 | -0.030991 |
| NUMB | numb homolog (Drosophila) | -0.0303492 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0303176 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | -0.0303084 |
| RPS27A | ribosomal protein S27a | -0.0302321 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0302208 |
| HMGA2 | high mobility group AT-hook 2 | -0.0295292 |
| S100A6 | S100 calcium binding protein A6 | -0.029468 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0290816 |
| OSMR | oncostatin M receptor | -0.0289517 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0281382 |
| NRP1 | neuropilin 1 | -0.0281221 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.0280781 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0278561 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0277728 |
| IL1B | interleukin 1, beta | -0.0276763 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0276571 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0275801 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0275118 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0274425 |
| CDK14 | cyclin-dependent kinase 14 | -0.027385 |
| EGR1 | early growth response 1 | -0.0272419 |
| EMP1 | epithelial membrane protein 1 | -0.0266259 |
| TNNC1 | troponin C type 1 (slow) | -0.0265818 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0265734 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | -0.0265275 |
| CALR | calreticulin | -0.0261806 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0260481 |
| CANX | calnexin | -0.0258191 |
| HDLBP | high density lipoprotein binding protein | -0.0254167 |
| HLA-B | major histocompatibility complex, class I, B | -0.0249127 |
| MAN2A1 | mannosidase, alpha, class 2A, member 1 | -0.0247614 |
| CLMP | CXADR-like membrane protein | -0.0246022 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0245712 |
| MSRB3 | methionine sulfoxide reductase B3 | -0.0245506 |
| OSBPL8 | oxysterol binding protein-like 8 | -0.0244915 |
