| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ornidazole perturbation in NCI-H2030 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Ornidazole_NCI-H2030 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GRAMD1B | GRAM domain containing 1B | 0.100335 |
| IGF2 | insulin-like growth factor 2 | 0.0827146 |
| WDR43 | WD repeat domain 43 | 0.0727395 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0712588 |
| APP | amyloid beta (A4) precursor protein | 0.066856 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0654101 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0636831 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0630037 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0625016 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0599799 |
| TPM3 | tropomyosin 3 | 0.059512 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0588433 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | 0.0586646 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.0582533 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0559832 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0518931 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0508949 |
| TXNRD1 | thioredoxin reductase 1 | 0.0485491 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0484079 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0483878 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0474962 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0464787 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0461321 |
| FAM168A | family with sequence similarity 168, member A | 0.0456053 |
| YBX3 | Y box binding protein 3 | 0.0438653 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0437239 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0434532 |
| RPL3 | ribosomal protein L3 | 0.042217 |
| TPD52 | tumor protein D52 | 0.0420744 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0413596 |
| LANCL1 | LanC lantibiotic synthetase component C-like 1 (bacterial) | 0.0411897 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0401925 |
| UBAP2L | ubiquitin associated protein 2-like | 0.040125 |
| JAK1 | Janus kinase 1 | 0.0399216 |
| WTAP | Wilms tumor 1 associated protein | 0.0394969 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | 0.0393256 |
| RBM39 | RNA binding motif protein 39 | 0.0388722 |
| FUS | FUS RNA binding protein | 0.0385332 |
| CYRIB | CYFIP related Rac1 interactor B | 0.0385317 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0385069 |
| ZNF292 | zinc finger protein 292 | 0.0382373 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | 0.0377302 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0374713 |
| NUP58 | nucleoporin 58 | 0.0374353 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.0373435 |
| PDE8A | phosphodiesterase 8A | 0.0373279 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0367504 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0365648 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0363926 |
| KLF6 | Kruppel-like factor 6 | 0.036035 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0360318 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0351423 |
| CTNNBL1 | catenin, beta like 1 | 0.0349575 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | 0.0347987 |
| MKI67 | marker of proliferation Ki-67 | 0.0347556 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0347348 |
| SPAG5 | sperm associated antigen 5 | 0.0339224 |
| SRSF5 | serine/arginine-rich splicing factor 5 | 0.0339038 |
| ACTN1 | actinin, alpha 1 | 0.0336002 |
| PRRC2A | proline-rich coiled-coil 2A | 0.0334533 |
| PTK2 | protein tyrosine kinase 2 | 0.0328929 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0327502 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0327434 |
| PTP4A1 | protein tyrosine phosphatase type IVA, member 1 | 0.0325946 |
| ABI1 | abl-interactor 1 | 0.0324806 |
| PLEC | plectin | 0.0321755 |
| PTMA | prothymosin, alpha | 0.0320927 |
| EWSR1 | EWS RNA-binding protein 1 | 0.0319428 |
| RBM33 | RNA binding motif protein 33 | 0.0318924 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | 0.0313187 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0311932 |
| NUDT21 | nudix (nucleoside diphosphate linked moiety X)-type motif 21 | 0.0311233 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0305083 |
| RPS12 | ribosomal protein S12 | 0.0304833 |
| USP3 | ubiquitin specific peptidase 3 | 0.0304645 |
| PFDN2 | prefoldin subunit 2 | 0.0303472 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0297205 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0293666 |
| UPP1 | uridine phosphorylase 1 | 0.0293288 |
| RRM2 | ribonucleotide reductase M2 | 0.028897 |
| MED15 | mediator complex subunit 15 | 0.0284978 |
| TRA2B | transformer 2 beta homolog (Drosophila) | 0.0284686 |
| KHDC4 | KH domain containing 4, pre-mRNA splicing factor | 0.0284683 |
| IQGAP3 | IQ motif containing GTPase activating protein 3 | 0.0281476 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0281063 |
| CASC3 | cancer susceptibility candidate 3 | 0.0278194 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0278067 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0277784 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0277707 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0277561 |
| LMNA | lamin A/C | 0.0276107 |
| MRTFA | myocardin related transcription factor A | 0.0274316 |
| SMAD3 | SMAD family member 3 | 0.0273376 |
| CABIN1 | calcineurin binding protein 1 | 0.0273185 |
| SPOPL | speckle-type POZ protein-like | 0.0272284 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | 0.027105 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0269899 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0267549 |
| RHEB | Ras homolog enriched in brain | 0.0266903 |
| SUB1 | SUB1 homolog (S. cerevisiae) | 0.0263744 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.263762 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.255054 |
| FTL | ferritin, light polypeptide | -0.154227 |
| VIM | vimentin | -0.141457 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.131556 |
| TMSB10 | thymosin beta 10 | -0.108309 |
| MT2A | metallothionein 2A | -0.0799136 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0784839 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0781924 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0625429 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0587043 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0542728 |
| HMGA1 | high mobility group AT-hook 1 | -0.0493294 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0485727 |
| RPS6 | ribosomal protein S6 | -0.0437094 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0412557 |
| S100A6 | S100 calcium binding protein A6 | -0.0405072 |
| POTEF | POTE ankyrin domain family, member F | -0.0376367 |
| LDHA | lactate dehydrogenase A | -0.0344597 |
| RPL19 | ribosomal protein L19 | -0.0340853 |
| PFN1 | profilin 1 | -0.0339709 |
| AHNAK | AHNAK nucleoprotein | -0.0339503 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0332967 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0314098 |
| IER3 | immediate early response 3 | -0.0311085 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0304612 |
| CMIP | c-Maf inducing protein | -0.0301724 |
| IL6 | interleukin 6 | -0.0289409 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0286888 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0274246 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.026328 |
| MCL1 | myeloid cell leukemia 1 | -0.0260516 |
| RPLP1 | ribosomal protein, large, P1 | -0.0258793 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0258071 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | -0.0251618 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0247849 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.0247154 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0245659 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0245395 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0244989 |
| PYGL | phosphorylase, glycogen, liver | -0.0240827 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0237731 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0237571 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0234005 |
| BICC1 | BicC family RNA binding protein 1 | -0.0232698 |
| NEGR1 | neuronal growth regulator 1 | -0.0224474 |
| OSMR | oncostatin M receptor | -0.0223383 |
| STC1 | stanniocalcin 1 | -0.0221995 |
| CUX1 | cut-like homeobox 1 | -0.0220966 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0218194 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0215785 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0215376 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0215228 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0214458 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.020968 |
| TMEM87A | transmembrane protein 87A | -0.0208008 |
| RPS16 | ribosomal protein S16 | -0.020591 |
| TRIP11 | thyroid hormone receptor interactor 11 | -0.0203621 |
| ENO1 | enolase 1, (alpha) | -0.0196711 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | -0.0194222 |
| UBC | ubiquitin C | -0.0193466 |
| MAP1B | microtubule-associated protein 1B | -0.0193045 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.01901 |
| ASTN2 | astrotactin 2 | -0.0186001 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0185884 |
| SMOC1 | SPARC related modular calcium binding 1 | -0.0183545 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0180486 |
| CDK13 | cyclin-dependent kinase 13 | -0.0179533 |
| EXOC6B | exocyst complex component 6B | -0.017898 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0177539 |
| S100A11 | S100 calcium binding protein A11 | -0.0176233 |
| EHBP1 | EH domain binding protein 1 | -0.0175209 |
| RPS5 | ribosomal protein S5 | -0.0174472 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0172446 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | -0.0171891 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.017185 |
| COX4I1 | cytochrome c oxidase subunit IV isoform 1 | -0.0168953 |
| ATF4 | activating transcription factor 4 | -0.0168833 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0168772 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0168102 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.016798 |
| COTL1 | coactosin-like F-actin binding protein 1 | -0.0167733 |
| RPS24 | ribosomal protein S24 | -0.016716 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0166293 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0166252 |
| MYADM | myeloid-associated differentiation marker | -0.0166164 |
| RPS19 | ribosomal protein S19 | -0.0164617 |
| ERBIN | erbb2 interacting protein | -0.0160114 |
| HLA-A | major histocompatibility complex, class I, A | -0.0159913 |
| PCNX4 | pecanex 4 | -0.0158137 |
| USP34 | ubiquitin specific peptidase 34 | -0.0157027 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | -0.0156631 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | -0.0155909 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.0155592 |
| RPLP0 | ribosomal protein, large, P0 | -0.0154546 |
| MYO9A | myosin IXA | -0.015353 |
| RPL35A | ribosomal protein L35a | -0.0153326 |
| PCBP1 | poly(rC) binding protein 1 | -0.0150293 |
| SVIL | supervillin | -0.014989 |
| ZNF609 | zinc finger protein 609 | -0.0148906 |
