| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ornidazole perturbation in NCI-H23 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Ornidazole_NCI-H23 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0909891 |
| TPM3 | tropomyosin 3 | 0.0779306 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.077856 |
| BBX | bobby sox homolog (Drosophila) | 0.075625 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0696398 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0695969 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0687435 |
| RAD51B | RAD51 paralog B | 0.0648698 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0616939 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0578428 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0568932 |
| RTN4 | reticulon 4 | 0.0533944 |
| RPS3 | ribosomal protein S3 | 0.0519773 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0517578 |
| ZNF292 | zinc finger protein 292 | 0.0478012 |
| MED13L | mediator complex subunit 13-like | 0.0476136 |
| SET | SET nuclear proto-oncogene | 0.0472726 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0470654 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0465407 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0465354 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0459852 |
| RSF1 | remodeling and spacing factor 1 | 0.0456728 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0448405 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0443152 |
| TPI1 | triosephosphate isomerase 1 | 0.0438533 |
| RPS8 | ribosomal protein S8 | 0.0436743 |
| RPL3 | ribosomal protein L3 | 0.0429007 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0427027 |
| OGA | O-GlcNAcase | 0.0426688 |
| YBX1 | Y box binding protein 1 | 0.0426448 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0425201 |
| SEPTIN7 | septin 7 | 0.0424702 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0411639 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0410414 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | 0.0405612 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0404342 |
| RPL37A | ribosomal protein L37a | 0.0400804 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0400551 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0390023 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0388892 |
| PTMA | prothymosin, alpha | 0.0386848 |
| CEP192 | centrosomal protein 192kDa | 0.0385705 |
| CTTN | cortactin | 0.0380376 |
| TFG | TRK-fused gene | 0.0374959 |
| RPS12 | ribosomal protein S12 | 0.0372771 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0372107 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0367 |
| PPME1 | protein phosphatase methylesterase 1 | 0.0362685 |
| RPS10 | ribosomal protein S10 | 0.0361014 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.0360901 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.035926 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0358679 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0356001 |
| SBF2 | SET binding factor 2 | 0.0354397 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0350957 |
| NUP58 | nucleoporin 58 | 0.0349859 |
| CHD1L | chromodomain helicase DNA binding protein 1-like | 0.0348091 |
| DENR | density-regulated protein | 0.0347228 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0344462 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0343863 |
| XPO1 | exportin 1 | 0.0338965 |
| COPA | coatomer protein complex, subunit alpha | 0.0334536 |
| PHF21A | PHD finger protein 21A | 0.0334032 |
| MEMO1 | mediator of cell motility 1 | 0.0328155 |
| FMNL2 | formin-like 2 | 0.0327943 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0325444 |
| PNN | pinin, desmosome associated protein | 0.0322515 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | 0.0321213 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0318878 |
| CDK19 | cyclin-dependent kinase 19 | 0.0316845 |
| PHIP | pleckstrin homology domain interacting protein | 0.0315509 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0313849 |
| RNF145 | ring finger protein 145 | 0.0313741 |
| RNF38 | ring finger protein 38 | 0.0313737 |
| CPSF6 | cleavage and polyadenylation specific factor 6, 68kDa | 0.03135 |
| PRELID2 | PRELI domain containing 2 | 0.0312648 |
| RPL37 | ribosomal protein L37 | 0.031165 |
| CDYL | chromodomain protein, Y-like | 0.0309314 |
| NCKAP1 | NCK-associated protein 1 | 0.0308081 |
| PTEN | phosphatase and tensin homolog | 0.0307162 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0306329 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | 0.0305035 |
| SINHCAF | SIN3-HDAC complex associated factor | 0.030314 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0296444 |
| PKM | pyruvate kinase, muscle | 0.0296094 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | 0.0295661 |
| KCMF1 | potassium channel modulatory factor 1 | 0.0294457 |
| PPHLN1 | periphilin 1 | 0.0293043 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0288081 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0287886 |
| MTPN | myotrophin | 0.0287651 |
| ENO1 | enolase 1, (alpha) | 0.0285051 |
| USP34 | ubiquitin specific peptidase 34 | 0.0284679 |
| DDX39B | DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B | 0.0284462 |
| POLR2B | polymerase (RNA) II (DNA directed) polypeptide B, 140kDa | 0.0283911 |
| RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 | 0.0283784 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0283499 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | 0.0282837 |
| ANO6 | anoctamin 6 | 0.0281965 |
| FOXO3 | forkhead box O3 | 0.028121 |
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.184224 |
| OSMR | oncostatin M receptor | -0.0944466 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0778234 |
| MCL1 | myeloid cell leukemia 1 | -0.069456 |
| PDE10A | phosphodiesterase 10A | -0.0590343 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0581703 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0580202 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0543415 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0519684 |
| NABP1 | nucleic acid binding protein 1 | -0.051197 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0510338 |
| YBX3 | Y box binding protein 3 | -0.0510247 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0492402 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0476193 |
| VCL | vinculin | -0.0461934 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0423253 |
| STC1 | stanniocalcin 1 | -0.0402034 |
| EGR1 | early growth response 1 | -0.0396757 |
| RNF213 | ring finger protein 213 | -0.0393106 |
| RIGI | RNA sensor RIG-I | -0.0388903 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0378556 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0375677 |
| HELZ2 | helicase with zinc finger 2, transcriptional coactivator | -0.0374995 |
| PLSCR1 | phospholipid scramblase 1 | -0.0367863 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0350471 |
| WNT2B | wingless-type MMTV integration site family, member 2B | -0.0346879 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0332852 |
| KLF6 | Kruppel-like factor 6 | -0.0329603 |
| PNPT1 | polyribonucleotide nucleotidyltransferase 1 | -0.0326598 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.032293 |
| AHNAK | AHNAK nucleoprotein | -0.0322173 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.031996 |
| TPM4 | tropomyosin 4 | -0.0311662 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0306831 |
| CDK17 | cyclin-dependent kinase 17 | -0.0305004 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0300541 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0299174 |
| KRT18 | keratin 18, type I | -0.0299058 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0297614 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | -0.0291788 |
| POTEF | POTE ankyrin domain family, member F | -0.0291042 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | -0.0290708 |
| PMP22 | peripheral myelin protein 22 | -0.0286582 |
| DHFR | dihydrofolate reductase | -0.0281189 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0278828 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0267514 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0265116 |
| SNAP25 | synaptosomal-associated protein, 25kDa | -0.0262234 |
| MX1 | MX dynamin-like GTPase 1 | -0.0255892 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0254574 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0252124 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0249516 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.0249415 |
| IER3 | immediate early response 3 | -0.0249132 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | -0.0246787 |
| PPP1R10 | protein phosphatase 1, regulatory subunit 10 | -0.024586 |
| CAVIN1 | caveolae associated protein 1 | -0.0244498 |
| TUBA1C | tubulin, alpha 1c | -0.0242964 |
| EXT1 | exostosin glycosyltransferase 1 | -0.024222 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | -0.0241758 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | -0.0234355 |
| ACTG1 | actin gamma 1 | -0.0232131 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.0230711 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | -0.0229393 |
| CCND1 | cyclin D1 | -0.0228362 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0227463 |
| TRIM56 | tripartite motif containing 56 | -0.0225585 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0222327 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | -0.022211 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0221189 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0220641 |
| NRG1 | neuregulin 1 | -0.0218191 |
| HLA-C | major histocompatibility complex, class I, C | -0.0217766 |
| EGFR | epidermal growth factor receptor | -0.021768 |
| FLNA | filamin A, alpha | -0.0213815 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0213771 |
| JUN | jun proto-oncogene | -0.021036 |
| ZNF644 | zinc finger protein 644 | -0.0206932 |
| TXNRD1 | thioredoxin reductase 1 | -0.020249 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | -0.0200298 |
| EPAS1 | endothelial PAS domain protein 1 | -0.0197545 |
| TPM2 | tropomyosin 2 (beta) | -0.0197264 |
| STX8 | syntaxin 8 | -0.0195669 |
| ARF1 | ADP-ribosylation factor 1 | -0.0191903 |
| RBBP6 | retinoblastoma binding protein 6 | -0.0187974 |
| LATS2 | large tumor suppressor kinase 2 | -0.0185801 |
| CALD1 | caldesmon 1 | -0.0183423 |
| PHF3 | PHD finger protein 3 | -0.0182716 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0180539 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.0179778 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0179091 |
| HLA-B | major histocompatibility complex, class I, B | -0.0178878 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0175202 |
| CLDN1 | claudin 1 | -0.0175117 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0173739 |
| CDC50A | cell division cycle 50 P4-ATPase accessory subunit A | -0.0173652 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0173572 |
| ATP11A | ATPase, class VI, type 11A | -0.0173481 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.0172989 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0172914 |
