| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ornidazole perturbation in NCI-H2347 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Ornidazole_NCI-H2347 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FNDC3B | fibronectin type III domain containing 3B | 0.148154 |
| GRB10 | growth factor receptor-bound protein 10 | 0.132625 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.103162 |
| TSC22D2 | TSC22 domain family, member 2 | 0.097008 |
| FAM13A | family with sequence similarity 13, member A | 0.0939577 |
| VEGFA | vascular endothelial growth factor A | 0.0920355 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0898323 |
| NDRG1 | N-myc downstream regulated 1 | 0.0817293 |
| TFG | TRK-fused gene | 0.080953 |
| PTK2 | protein tyrosine kinase 2 | 0.0747356 |
| ASPH | aspartate beta-hydroxylase | 0.0743057 |
| RNF145 | ring finger protein 145 | 0.0738838 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0729384 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0703842 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0697753 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0677888 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0658033 |
| ZNF292 | zinc finger protein 292 | 0.0655748 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.065304 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0641659 |
| COPA | coatomer protein complex, subunit alpha | 0.0630373 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | 0.061 |
| NAV2 | neuron navigator 2 | 0.0600532 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0547586 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0547028 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0540112 |
| PLEC | plectin | 0.0529525 |
| MSN | moesin | 0.0523182 |
| PGK1 | phosphoglycerate kinase 1 | 0.051616 |
| UPP1 | uridine phosphorylase 1 | 0.051571 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.050908 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0500551 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0499288 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0497526 |
| TOP1 | topoisomerase (DNA) I | 0.0482972 |
| FLNB | filamin B, beta | 0.0478513 |
| RCOR1 | REST corepressor 1 | 0.0469152 |
| TPM3 | tropomyosin 3 | 0.04678 |
| NUP58 | nucleoporin 58 | 0.0466887 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.043724 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | 0.0434634 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0434367 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0425442 |
| PKM | pyruvate kinase, muscle | 0.0424937 |
| WAC | WW domain containing adaptor with coiled-coil | 0.042287 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0422717 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0414936 |
| MXD1 | MAX dimerization protein 1 | 0.0413023 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.04129 |
| QKI | QKI, KH domain containing, RNA binding | 0.0409824 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.040449 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0403664 |
| SETD5 | SET domain containing 5 | 0.0397894 |
| RPL3 | ribosomal protein L3 | 0.0397388 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0394747 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0394644 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0390775 |
| RYBP | RING1 and YY1 binding protein | 0.0387285 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0382831 |
| SMG7 | SMG7 nonsense mediated mRNA decay factor | 0.0381818 |
| CCNY | cyclin Y | 0.0368438 |
| TRA2B | transformer 2 beta homolog (Drosophila) | 0.0364541 |
| MAL2 | mal, T-cell differentiation protein 2 (gene/pseudogene) | 0.0360924 |
| NCKAP1 | NCK-associated protein 1 | 0.0358705 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.0353006 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0352877 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0346388 |
| RYK | receptor-like tyrosine kinase | 0.0344842 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0344538 |
| CLIP4 | CAP-GLY domain containing linker protein family, member 4 | 0.0343268 |
| KRT8 | keratin 8, type II | 0.0342735 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0342458 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0342135 |
| PUM1 | pumilio RNA-binding family member 1 | 0.034189 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0341207 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0339453 |
| RACK1 | receptor for activated C kinase 1 | 0.0334537 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0334458 |
| SLMAP | sarcolemma associated protein | 0.0333198 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0333129 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.032667 |
| CDC73 | cell division cycle 73 | 0.0321628 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0321376 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0320735 |
| PAPOLA | poly(A) polymerase alpha | 0.03205 |
| AHDC1 | AT hook, DNA binding motif, containing 1 | 0.032 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0317376 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0314165 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0313468 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0311166 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0309558 |
| MSMO1 | methylsterol monooxygenase 1 | 0.0305671 |
| CTBP2 | C-terminal binding protein 2 | 0.0305022 |
| CCNL1 | cyclin L1 | 0.0303682 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0303078 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | 0.0298798 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0298102 |
| PARD3 | par-3 family cell polarity regulator | 0.0295993 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0295797 |
| YAP1 | Yes-associated protein 1 | 0.0293495 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FTL | ferritin, light polypeptide | -0.192486 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.152542 |
| FN1 | fibronectin 1 | -0.150865 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.129591 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.125558 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.121361 |
| TMSB10 | thymosin beta 10 | -0.112274 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0858784 |
| S100A6 | S100 calcium binding protein A6 | -0.0785339 |
| MT2A | metallothionein 2A | -0.0777103 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0725869 |
| RPLP1 | ribosomal protein, large, P1 | -0.0632911 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0549884 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0548764 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0532674 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0505035 |
| SDC4 | syndecan 4 | -0.0500998 |
| LAMB3 | laminin, beta 3 | -0.0499681 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0481304 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0476464 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0466377 |
| CSTB | cystatin B (stefin B) | -0.0464192 |
| RPL35A | ribosomal protein L35a | -0.0464118 |
| TMSB4X | thymosin beta 4, X-linked | -0.0458169 |
| HMGA1 | high mobility group AT-hook 1 | -0.045292 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0445529 |
| F11R | F11 receptor | -0.0435583 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0416711 |
| RPS6 | ribosomal protein S6 | -0.0415443 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0401041 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0400295 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | -0.0398025 |
| FBXO32 | F-box protein 32 | -0.0395695 |
| RPS19 | ribosomal protein S19 | -0.0392673 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.038385 |
| TXNIP | thioredoxin interacting protein | -0.0376489 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0374666 |
| CD2AP | CD2-associated protein | -0.0373833 |
| LMO7 | LIM domain 7 | -0.0373184 |
| RPL34 | ribosomal protein L34 | -0.0364556 |
| GNAS | GNAS complex locus | -0.0355077 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.035192 |
| S100A10 | S100 calcium binding protein A10 | -0.033704 |
| RPLP2 | ribosomal protein, large, P2 | -0.0335115 |
| HLA-A | major histocompatibility complex, class I, A | -0.0334515 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0328364 |
| TPM4 | tropomyosin 4 | -0.0317904 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0313646 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0313229 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0313147 |
| HLA-E | major histocompatibility complex, class I, E | -0.0311494 |
| RRBP1 | ribosome binding protein 1 | -0.0310095 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0309249 |
| MACC1 | metastasis associated in colon cancer 1 | -0.0296233 |
| CLDN4 | claudin 4 | -0.0295089 |
| ARF1 | ADP-ribosylation factor 1 | -0.0291535 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0290701 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0285543 |
| RPL12 | ribosomal protein L12 | -0.0281806 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0280805 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0280514 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | -0.0271804 |
| MYO1E | myosin IE | -0.0267112 |
| ACTG1 | actin gamma 1 | -0.0266532 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0264488 |
| S100A11 | S100 calcium binding protein A11 | -0.0261392 |
| AHNAK | AHNAK nucleoprotein | -0.0256864 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0256532 |
| DSG2 | desmoglein 2 | -0.0248903 |
| HLA-B | major histocompatibility complex, class I, B | -0.0247179 |
| MAP1B | microtubule-associated protein 1B | -0.0244781 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0242409 |
| RPL32 | ribosomal protein L32 | -0.0238948 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.023893 |
| H1-0 | H1.0 linker histone | -0.0238182 |
| GNAI2 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 | -0.0237357 |
| CRABP2 | cellular retinoic acid binding protein 2 | -0.023638 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0235048 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0230618 |
| CANX | calnexin | -0.0229983 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0229233 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0226173 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain | -0.0224909 |
| RPL8 | ribosomal protein L8 | -0.0223768 |
| FNBP4 | formin binding protein 4 | -0.0219619 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0219517 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0214825 |
| HDLBP | high density lipoprotein binding protein | -0.0212933 |
| VGLL3 | vestigial-like family member 3 | -0.0212259 |
| CCND1 | cyclin D1 | -0.0205812 |
| KRT19 | keratin 19, type I | -0.020398 |
| CTSS | cathepsin S | -0.0203275 |
| RNF213 | ring finger protein 213 | -0.0203249 |
| SMIM14 | small integral membrane protein 14 | -0.0200974 |
| FBXL20 | F-box and leucine-rich repeat protein 20 | -0.019415 |
| CDCP1 | CUB domain containing protein 1 | -0.019201 |
| SLC38A1 | solute carrier family 38, member 1 | -0.019114 |
| MX2 | MX dynamin-like GTPase 2 | -0.0191024 |
| RPL36 | ribosomal protein L36 | -0.0189329 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0188874 |
