| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ornidazole perturbation in NCI-H460 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Ornidazole_NCI-H460 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EFNA5 | ephrin-A5 | 0.234509 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.189652 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.139871 |
| ASPH | aspartate beta-hydroxylase | 0.125403 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.119295 |
| GDA | guanine deaminase | 0.113472 |
| TXNRD1 | thioredoxin reductase 1 | 0.100309 |
| EPB41L3 | erythrocyte membrane protein band 4.1-like 3 | 0.0949976 |
| PCBP3 | poly(rC) binding protein 3 | 0.0872025 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0803774 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.0778799 |
| NRCAM | neuronal cell adhesion molecule | 0.0700447 |
| PTGR1 | prostaglandin reductase 1 | 0.0670149 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0647187 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0572438 |
| SLC39A8 | solute carrier family 39 (zinc transporter), member 8 | 0.0567166 |
| NEK7 | NIMA-related kinase 7 | 0.0544061 |
| MYOF | myoferlin | 0.0537872 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0534102 |
| PGK1 | phosphoglycerate kinase 1 | 0.0533649 |
| GRAMD1B | GRAM domain containing 1B | 0.0496806 |
| MFF | mitochondrial fission factor | 0.0488883 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0480842 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 0.0465071 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0457915 |
| CTSC | cathepsin C | 0.0437035 |
| FAM13A | family with sequence similarity 13, member A | 0.0423259 |
| AGFG1 | ArfGAP with FG repeats 1 | 0.0411762 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.0410831 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0396173 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.039188 |
| SMYD3 | SET and MYND domain containing 3 | 0.0381423 |
| FLNB | filamin B, beta | 0.0380934 |
| ZNF292 | zinc finger protein 292 | 0.038063 |
| OGA | O-GlcNAcase | 0.0378257 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.037688 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0375349 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0374195 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0369293 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.0366764 |
| WDFY2 | WD repeat and FYVE domain containing 2 | 0.036135 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0360138 |
| TNPO1 | transportin 1 | 0.0357569 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0355192 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0352617 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | 0.0347863 |
| RTN4 | reticulon 4 | 0.0345956 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0342869 |
| PDE10A | phosphodiesterase 10A | 0.0332852 |
| TMX4 | thioredoxin-related transmembrane protein 4 | 0.0329351 |
| PYGL | phosphorylase, glycogen, liver | 0.0327388 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.031813 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | 0.0311565 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.031033 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0306894 |
| MKI67 | marker of proliferation Ki-67 | 0.0297831 |
| CHD1L | chromodomain helicase DNA binding protein 1-like | 0.0295306 |
| TNFRSF19 | tumor necrosis factor receptor superfamily, member 19 | 0.0293205 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | 0.0287475 |
| COL4A5 | collagen, type IV, alpha 5 | 0.028619 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0283147 |
| PTEN | phosphatase and tensin homolog | 0.0281173 |
| GPAT3 | glycerol-3-phosphate acyltransferase 3 | 0.0280537 |
| PRKD3 | protein kinase D3 | 0.0277876 |
| CENPF | centromere protein F, 350/400kDa | 0.0269814 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0267796 |
| NGLY1 | N-glycanase 1 | 0.0264109 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0263398 |
| PHF20 | PHD finger protein 20 | 0.0260142 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0255561 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0254601 |
| COL4A6 | collagen, type IV, alpha 6 | 0.0253185 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0249398 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0248129 |
| ENAH | enabled homolog (Drosophila) | 0.0245565 |
| SBF2 | SET binding factor 2 | 0.024216 |
| MTR | 5-methyltetrahydrofolate-homocysteine methyltransferase | 0.0239271 |
| RPL4 | ribosomal protein L4 | 0.0239037 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | 0.0238211 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0237644 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0237208 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0237048 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0233287 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0233179 |
| PRKACB | protein kinase, cAMP-dependent, catalytic, beta | 0.0232387 |
| SUB1 | SUB1 homolog (S. cerevisiae) | 0.0228967 |
| BDNF | brain-derived neurotrophic factor | 0.0228053 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0227015 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0226925 |
| TPM3 | tropomyosin 3 | 0.0226818 |
| SEPTIN10 | septin 10 | 0.0226802 |
| ATXN1 | ataxin 1 | 0.0226249 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0225529 |
| GPRIN3 | GPRIN family member 3 | 0.0223287 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.0221743 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0221616 |
| RAB3B | RAB3B, member RAS oncogene family | 0.0221039 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0220965 |
| RPL3 | ribosomal protein L3 | 0.0219622 |
| ANO6 | anoctamin 6 | 0.0219123 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.325644 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.156262 |
| FN1 | fibronectin 1 | -0.139469 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.121807 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0938188 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0826551 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0699872 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0600152 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0570356 |
| PM20D1 | peptidase M20 domain containing 1 | -0.0526424 |
| RPS6 | ribosomal protein S6 | -0.0523046 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0519638 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0476965 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0449327 |
| VCL | vinculin | -0.0437188 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0418104 |
| SMOC1 | SPARC related modular calcium binding 1 | -0.0410563 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0407246 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0393261 |
| SMAD2 | SMAD family member 2 | -0.0366441 |
| P3H2 | prolyl 3-hydroxylase 2 | -0.0353349 |
| CDH13 | cadherin 13 | -0.0353316 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | -0.0352378 |
| ADGRD1 | adhesion G protein-coupled receptor D1 | -0.0352284 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | -0.0346659 |
| FTL | ferritin, light polypeptide | -0.034269 |
| VIM | vimentin | -0.033855 |
| CANX | calnexin | -0.0329337 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0322993 |
| RPLP1 | ribosomal protein, large, P1 | -0.0319009 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0317328 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0313698 |
| MCL1 | myeloid cell leukemia 1 | -0.0308728 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0299356 |
| DPP10 | dipeptidyl-peptidase 10 (non-functional) | -0.0290064 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | -0.0279484 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0275615 |
| EGR1 | early growth response 1 | -0.0273786 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0273169 |
| LSAMP | limbic system-associated membrane protein | -0.0269375 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0256818 |
| POTEF | POTE ankyrin domain family, member F | -0.0251891 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0243404 |
| RHOB | ras homolog family member B | -0.0242068 |
| PDLIM5 | PDZ and LIM domain 5 | -0.023788 |
| EPHA4 | EPH receptor A4 | -0.0236568 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0234151 |
| PCBP2 | poly(rC) binding protein 2 | -0.0226064 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | -0.0222604 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0218967 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.021355 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0211115 |
| OASL | 2'-5'-oligoadenylate synthetase-like | -0.0210505 |
| MAP7 | microtubule-associated protein 7 | -0.0207772 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0206601 |
| AUTS2 | autism susceptibility candidate 2 | -0.0204697 |
| IL6 | interleukin 6 | -0.0202213 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0197761 |
| CALR | calreticulin | -0.0197022 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0195989 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | -0.0193461 |
| SVIL | supervillin | -0.0193454 |
| RPS4X | ribosomal protein S4, X-linked | -0.018703 |
| FLNA | filamin A, alpha | -0.0185199 |
| RPL35A | ribosomal protein L35a | -0.0184793 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | -0.0184683 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.018414 |
| S100A6 | S100 calcium binding protein A6 | -0.0180143 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.0178758 |
| INTS6 | integrator complex subunit 6 | -0.0177317 |
| BSG | basigin (Ok blood group) | -0.0175685 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | -0.0173781 |
| CADM2 | cell adhesion molecule 2 | -0.0173777 |
| CUX1 | cut-like homeobox 1 | -0.0173268 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0172957 |
| CHD1 | chromodomain helicase DNA binding protein 1 | -0.0170997 |
| TMSB10 | thymosin beta 10 | -0.0170831 |
| RPS19 | ribosomal protein S19 | -0.0170074 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0168469 |
| OXSR1 | oxidative stress responsive 1 | -0.0164446 |
| HYOU1 | hypoxia up-regulated 1 | -0.0164022 |
| NABP1 | nucleic acid binding protein 1 | -0.0163653 |
| AEBP2 | AE binding protein 2 | -0.0162852 |
| TOB1 | transducer of ERBB2, 1 | -0.0160582 |
| OGDH | oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) | -0.0159739 |
| ATF4 | activating transcription factor 4 | -0.0159687 |
| FAM107B | family with sequence similarity 107, member B | -0.0158452 |
| DHFR | dihydrofolate reductase | -0.0158337 |
| SFTPA2 | surfactant protein A2 | -0.0156883 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0155802 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0155767 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | -0.0155146 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.015355 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0152385 |
| ADARB2 | adenosine deaminase, RNA-specific, B2 (non-functional) | -0.0151563 |
| ANTXR1 | anthrax toxin receptor 1 | -0.0151351 |
| RAB31 | RAB31, member RAS oncogene family | -0.0149346 |
| EZR | ezrin | -0.0149209 |
| GNAS | GNAS complex locus | -0.0149071 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 | -0.0147023 |
