| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ornidazole perturbation in NCI-H596 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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183 genes differentially expressed following the Ornidazole_NCI-H596 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NLGN1 | neuroligin 1 | 0.187608 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.182877 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.177441 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.162634 |
| FAM13A | family with sequence similarity 13, member A | 0.134374 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.133323 |
| STC1 | stanniocalcin 1 | 0.128135 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.116737 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.108731 |
| USP34 | ubiquitin specific peptidase 34 | 0.103026 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.102146 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0992382 |
| NKTR | natural killer cell triggering receptor | 0.0990711 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.0978212 |
| TXNRD1 | thioredoxin reductase 1 | 0.0906584 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.088295 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.084752 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0819208 |
| RORA | RAR-related orphan receptor A | 0.0704964 |
| DST | dystonin | 0.0694418 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.068563 |
| RBM39 | RNA binding motif protein 39 | 0.0683629 |
| NCOR1 | nuclear receptor corepressor 1 | 0.0670108 |
| VMP1 | vacuole membrane protein 1 | 0.060243 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0563366 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0556951 |
| EFNA5 | ephrin-A5 | 0.0505681 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0503287 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.0502963 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0498273 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0484813 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0477753 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0474623 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.046824 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0451587 |
| ASPH | aspartate beta-hydroxylase | 0.0441914 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0416368 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.040661 |
| SBF2 | SET binding factor 2 | 0.0384164 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0377942 |
| ZNF292 | zinc finger protein 292 | 0.037359 |
| RAD51B | RAD51 paralog B | 0.0367931 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.035216 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0352029 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0349473 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0348365 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0328648 |
| EGFR | epidermal growth factor receptor | 0.0328347 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0327117 |
| PRRC2C | proline-rich coiled-coil 2C | 0.032253 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0316718 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0291932 |
| FNIP1 | folliculin interacting protein 1 | 0.0284771 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0274656 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0266409 |
| PTK2 | protein tyrosine kinase 2 | 0.0259651 |
| GOLGA4 | golgin A4 | 0.0204675 |
| SETD5 | SET domain containing 5 | 0.0202282 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.019813 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0196115 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0193006 |
| CDK6 | cyclin-dependent kinase 6 | 0.0180949 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0172727 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0171354 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0147994 |
| EZR | ezrin | 0.0141463 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0140157 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.0139161 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.0135174 |
| B2M | beta-2-microglobulin | 0.0131827 |
| NF1 | neurofibromin 1 | 0.0125971 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0122825 |
| VIM | vimentin | 0.0101528 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.00825921 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0077854 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.00627424 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | 0.00602706 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.00527079 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.00522721 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.00508367 |
| PPP2R5C | protein phosphatase 2, regulatory subunit B', gamma | 0.00310984 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.00145921 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.00118636 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.157995 |
| JMJD1C | jumonji domain containing 1C | -0.113291 |
| PTMA | prothymosin, alpha | -0.112205 |
| LMO7 | LIM domain 7 | -0.10472 |
| ITGA6 | integrin, alpha 6 | -0.102657 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0992528 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0989685 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0989355 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0946159 |
| RPLP1 | ribosomal protein, large, P1 | -0.0936608 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0927247 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | -0.0880857 |
| PRKCA | protein kinase C, alpha | -0.0848886 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0844977 |
| ATP11A | ATPase, class VI, type 11A | -0.0795197 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0786105 |
| RPS16 | ribosomal protein S16 | -0.0754111 |
| HMGA2 | high mobility group AT-hook 2 | -0.0736366 |
| PEG10 | paternally expressed 10 | -0.071947 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0694936 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.0672834 |
| SNX9 | sorting nexin 9 | -0.0669642 |
| GOLGB1 | golgin B1 | -0.0642295 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0609377 |
| NAV2 | neuron navigator 2 | -0.0554339 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0554212 |
| SEMA3D | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D | -0.0534392 |
| NDRG1 | N-myc downstream regulated 1 | -0.0522669 |
| CADM2 | cell adhesion molecule 2 | -0.0516105 |
| MYO10 | myosin X | -0.0509515 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0505072 |
| MT2A | metallothionein 2A | -0.0495699 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0491338 |
| RNF213 | ring finger protein 213 | -0.0487888 |
| RBM25 | RNA binding motif protein 25 | -0.0486622 |
| PCBP2 | poly(rC) binding protein 2 | -0.0473558 |
| BBX | bobby sox homolog (Drosophila) | -0.0473222 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0464712 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0457234 |
| RPLP2 | ribosomal protein, large, P2 | -0.045698 |
| ANXA2 | annexin A2 | -0.0442849 |
| ATXN1 | ataxin 1 | -0.0439885 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0439769 |
| VCL | vinculin | -0.0434429 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0432457 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | -0.0427766 |
| EGR1 | early growth response 1 | -0.0421987 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0419671 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0393387 |
| RPL37 | ribosomal protein L37 | -0.0391106 |
| RPS8 | ribosomal protein S8 | -0.0390579 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0388392 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0374168 |
| FMNL2 | formin-like 2 | -0.0371519 |
| STAG2 | stromal antigen 2 | -0.0361843 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0359192 |
| ATF6 | activating transcription factor 6 | -0.0358372 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0350293 |
| ZNF608 | zinc finger protein 608 | -0.0344908 |
| RPL23 | ribosomal protein L23 | -0.0338013 |
| TMSB10 | thymosin beta 10 | -0.0335391 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0329769 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | -0.0311315 |
| SP100 | SP100 nuclear antigen | -0.0308421 |
| KAT6B | K(lysine) acetyltransferase 6B | -0.0307773 |
| UBE2K | ubiquitin-conjugating enzyme E2K | -0.0305682 |
| OSMR | oncostatin M receptor | -0.0299342 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0297551 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0293282 |
| CD44 | CD44 molecule (Indian blood group) | -0.0292978 |
| KRT8 | keratin 8, type II | -0.0291741 |
| ENO1 | enolase 1, (alpha) | -0.0272901 |
| MYO1E | myosin IE | -0.0270615 |
| RAB2A | RAB2A, member RAS oncogene family | -0.0269048 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0267616 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0265483 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0252546 |
| PDE10A | phosphodiesterase 10A | -0.0247753 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.0247599 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0247129 |
| TPM4 | tropomyosin 4 | -0.0233846 |
| ARRDC3 | arrestin domain containing 3 | -0.0207524 |
| PHF3 | PHD finger protein 3 | -0.0204375 |
| RPL26 | ribosomal protein L26 | -0.0200439 |
| CARD16 | caspase recruitment domain family, member 16 | -0.0200291 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0169744 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0165512 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | -0.0165309 |
| SLTM | SAFB-like, transcription modulator | -0.0159141 |
| WASF2 | WAS protein family, member 2 | -0.0153452 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.013975 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0130004 |
| RPS6 | ribosomal protein S6 | -0.0125343 |
| CANX | calnexin | -0.0122368 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | -0.0121717 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0121232 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0111912 |
| XRN2 | 5'-3' exoribonuclease 2 | -0.00992897 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.00947949 |
| PGK1 | phosphoglycerate kinase 1 | -0.00939022 |
