| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ornidazole perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Ornidazole_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TSC22D2 | TSC22 domain family, member 2 | 0.113937 |
| COL5A2 | collagen, type V, alpha 2 | 0.0999304 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0912233 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0867927 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0778109 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0726482 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0708695 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0673859 |
| PLPP1 | phospholipid phosphatase 1 | 0.0663346 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0624207 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.062089 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0609614 |
| UPP1 | uridine phosphorylase 1 | 0.0537631 |
| TMSB4X | thymosin beta 4, X-linked | 0.0534819 |
| PDGFC | platelet derived growth factor C | 0.0521263 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0514107 |
| SRPK2 | SRSF protein kinase 2 | 0.0512901 |
| CDC73 | cell division cycle 73 | 0.0496254 |
| FUS | FUS RNA binding protein | 0.0468879 |
| RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 | 0.0468488 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0462542 |
| NFIA | nuclear factor I/A | 0.0450452 |
| STRN3 | striatin, calmodulin binding protein 3 | 0.0443572 |
| HDAC9 | histone deacetylase 9 | 0.043907 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.0432742 |
| ZNF217 | zinc finger protein 217 | 0.042545 |
| ZNF292 | zinc finger protein 292 | 0.042297 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0418106 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0408361 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | 0.0404097 |
| MTF2 | metal response element binding transcription factor 2 | 0.0392569 |
| CCN2 | cellular communication network factor 2 | 0.0381922 |
| JMJD1C | jumonji domain containing 1C | 0.0379916 |
| ATXN2 | ataxin 2 | 0.0376109 |
| ANK2 | ankyrin 2, neuronal | 0.0374664 |
| ANKRD33B | ankyrin repeat domain 33B | 0.0365691 |
| CRISPLD1 | cysteine-rich secretory protein LCCL domain containing 1 | 0.036002 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0355782 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0354518 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0353555 |
| ANXA1 | annexin A1 | 0.0351546 |
| RYBP | RING1 and YY1 binding protein | 0.0348667 |
| POLR2B | polymerase (RNA) II (DNA directed) polypeptide B, 140kDa | 0.0346818 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0346158 |
| MB21D2 | Mab-21 domain containing 2 | 0.033332 |
| SMG7 | SMG7 nonsense mediated mRNA decay factor | 0.0332601 |
| SFRP4 | secreted frizzled-related protein 4 | 0.033135 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0319161 |
| PLEKHB2 | pleckstrin homology domain containing, family B (evectins) member 2 | 0.0318475 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0318335 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0317151 |
| PER1 | period circadian clock 1 | 0.031684 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | 0.0316774 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0315225 |
| YES1 | YES proto-oncogene 1, Src family tyrosine kinase | 0.0313725 |
| FIP1L1 | factor interacting with PAPOLA and CPSF1 | 0.0311344 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.0306936 |
| AK1 | adenylate kinase 1 | 0.030063 |
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 | 0.0299441 |
| CORO1C | coronin, actin binding protein, 1C | 0.0293882 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | 0.0291538 |
| TPD52 | tumor protein D52 | 0.028861 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 | 0.0287425 |
| TMEM64 | transmembrane protein 64 | 0.0285506 |
| RPL4 | ribosomal protein L4 | 0.0285184 |
| FAM171B | family with sequence similarity 171, member B | 0.028445 |
| PLK2 | polo-like kinase 2 | 0.028162 |
| PPP4R1 | protein phosphatase 4, regulatory subunit 1 | 0.0279709 |
| GASK1B | golgi associated kinase 1B | 0.0278466 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | 0.0277621 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0276139 |
| NONO | non-POU domain containing, octamer-binding | 0.0275412 |
| MED13L | mediator complex subunit 13-like | 0.0273914 |
| ZDHHC17 | zinc finger, DHHC-type containing 17 | 0.0270847 |
| RPL3 | ribosomal protein L3 | 0.0269106 |
| XPO1 | exportin 1 | 0.0266333 |
| OGA | O-GlcNAcase | 0.0266198 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0265694 |
| CPNE8 | copine VIII | 0.0264997 |
| NCKAP1 | NCK-associated protein 1 | 0.0264363 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0260839 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0259749 |
| SUB1 | SUB1 homolog (S. cerevisiae) | 0.0257813 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0253824 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0253468 |
| UBA2 | ubiquitin-like modifier activating enzyme 2 | 0.0252976 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0251052 |
| ACTN4 | actinin, alpha 4 | 0.0249004 |
| WASL | Wiskott-Aldrich syndrome-like | 0.0248816 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0248695 |
| PDCD6IP | programmed cell death 6 interacting protein | 0.0248445 |
| LSM14A | LSM14A, SCD6 homolog A (S. cerevisiae) | 0.0246834 |
| RLF | rearranged L-myc fusion | 0.0246694 |
| RIOK3 | RIO kinase 3 | 0.0244613 |
| FEM1C | fem-1 homolog c (C. elegans) | 0.0242999 |
| EVI5 | ecotropic viral integration site 5 | 0.0242807 |
| FNBP1L | formin binding protein 1-like | 0.0242653 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0242289 |
| DLX2 | distal-less homeobox 2 | 0.0236401 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0235421 |
| Symbol | Name | Standardized Value |
|---|---|---|
| COL11A1 | collagen, type XI, alpha 1 | -0.171877 |
| CADM2 | cell adhesion molecule 2 | -0.147703 |
| VIM | vimentin | -0.134906 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | -0.132561 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | -0.078924 |
| PEG10 | paternally expressed 10 | -0.0780592 |
| RPS6 | ribosomal protein S6 | -0.0765796 |
| GPC3 | glypican 3 | -0.0714714 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | -0.0610658 |
| COL3A1 | collagen, type III, alpha 1 | -0.0605219 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.0582529 |
| DEK | DEK proto-oncogene | -0.0576663 |
| NCAM2 | neural cell adhesion molecule 2 | -0.0509499 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0486073 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0455071 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0446301 |
| SIK3 | SIK family kinase 3 | -0.0445136 |
| COL1A2 | collagen, type I, alpha 2 | -0.0443437 |
| HS3ST5 | heparan sulfate (glucosamine) 3-O-sulfotransferase 5 | -0.0441361 |
| SNX6 | sorting nexin 6 | -0.0423476 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0420835 |
| AHNAK | AHNAK nucleoprotein | -0.0420827 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0415717 |
| POTEF | POTE ankyrin domain family, member F | -0.0412584 |
| ZC3H12B | zinc finger CCCH-type containing 12B | -0.0406951 |
| PTMA | prothymosin, alpha | -0.0401586 |
| ADGRV1 | adhesion G protein-coupled receptor V1 | -0.039857 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.039649 |
| RASAL2 | RAS protein activator like 2 | -0.0392918 |
| PHF3 | PHD finger protein 3 | -0.0367984 |
| TUBA1B | tubulin, alpha 1b | -0.0360108 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0350667 |
| RAD51B | RAD51 paralog B | -0.0350475 |
| CSMD3 | CUB and Sushi multiple domains 3 | -0.0347169 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0342234 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0341788 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0329415 |
| TMSB10 | thymosin beta 10 | -0.0323494 |
| GALNTL6 | polypeptide N-acetylgalactosaminyltransferase-like 6 | -0.0322419 |
| HMGA1 | high mobility group AT-hook 1 | -0.0317888 |
| CTNNA3 | catenin (cadherin-associated protein), alpha 3 | -0.0310668 |
| TULP4 | tubby like protein 4 | -0.0309726 |
| HMCN1 | hemicentin 1 | -0.0299893 |
| ERBIN | erbb2 interacting protein | -0.0294824 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0293327 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0280823 |
| PCDH9 | protocadherin 9 | -0.0279794 |
| CANX | calnexin | -0.0278986 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0268289 |
| PRRC2B | proline-rich coiled-coil 2B | -0.0267748 |
| TENM3 | teneurin transmembrane protein 3 | -0.0267388 |
| TXNRD1 | thioredoxin reductase 1 | -0.0260533 |
| VGLL3 | vestigial-like family member 3 | -0.0260401 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.0260096 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0258311 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0254902 |
| DHFR | dihydrofolate reductase | -0.0252824 |
| ITSN1 | intersectin 1 (SH3 domain protein) | -0.025231 |
| RPS2 | ribosomal protein S2 | -0.025216 |
| CCDC102B | coiled-coil domain containing 102B | -0.0242418 |
| FRY | furry homolog (Drosophila) | -0.0241951 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0241274 |
| TPTE | transmembrane phosphatase with tensin homology | -0.0241201 |
| SMYD3 | SET and MYND domain containing 3 | -0.0239871 |
| MCL1 | myeloid cell leukemia 1 | -0.0238487 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0238438 |
| DOCK1 | dedicator of cytokinesis 1 | -0.0237942 |
| TARS1 | threonyl-tRNA synthetase 1 | -0.0235401 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0234268 |
| CAVIN1 | caveolae associated protein 1 | -0.023252 |
| MAP1B | microtubule-associated protein 1B | -0.0230853 |
| SRP54 | signal recognition particle 54kDa | -0.0230348 |
| GLI3 | GLI family zinc finger 3 | -0.0229215 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0229004 |
| LARS1 | leucyl-tRNA synthetase 1 | -0.0228237 |
| TPM4 | tropomyosin 4 | -0.0225862 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0225531 |
| CBX3 | chromobox homolog 3 | -0.0225101 |
| RFPL4B | ret finger protein-like 4B | -0.0224534 |
| MACROH2A1 | macroH2A.1 histone | -0.0222246 |
| MRPS30 | mitochondrial ribosomal protein S30 | -0.022205 |
| LPGAT1 | lysophosphatidylglycerol acyltransferase 1 | -0.0221306 |
| ATF7IP | activating transcription factor 7 interacting protein | -0.022025 |
| RPL35A | ribosomal protein L35a | -0.0219971 |
| RPL19 | ribosomal protein L19 | -0.0219305 |
| LRRC4C | leucine rich repeat containing 4C | -0.0217243 |
| TPR | translocated promoter region, nuclear basket protein | -0.0216628 |
| SLC25A24 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24 | -0.0215168 |
| FAM177A1 | family with sequence similarity 177, member A1 | -0.0208816 |
| BPTF | bromodomain PHD finger transcription factor | -0.0207999 |
| NSD1 | nuclear receptor binding SET domain protein 1 | -0.0207826 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0206808 |
| UBE2B | ubiquitin-conjugating enzyme E2B | -0.0206562 |
| RPL31 | ribosomal protein L31 | -0.020566 |
| CUX1 | cut-like homeobox 1 | -0.0204667 |
| GNAS | GNAS complex locus | -0.0203964 |
| ADGRL1 | adhesion G protein-coupled receptor L1 | -0.0200849 |
| DCAF7 | DDB1 and CUL4 associated factor 7 | -0.0200763 |
| WDR70 | WD repeat domain 70 | -0.0198968 |
| USP33 | ubiquitin specific peptidase 33 | -0.0197287 |
