Ornidazole_SNU-1 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Ornidazole perturbation in SNU-1 cell line (Tahoe Therapeutics)
Similar Terms
Downloads & Tools

Genes

200 genes differentially expressed following the Ornidazole_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
ZNF292 zinc finger protein 292 0.120234
ADAM10 ADAM metallopeptidase domain 10 0.115389
GBE1 glucan (1,4-alpha-), branching enzyme 1 0.103121
EML4 echinoderm microtubule associated protein like 4 0.0852795
SOX6 SRY (sex determining region Y)-box 6 0.0835921
PRELID2 PRELI domain containing 2 0.0766555
ANKRD12 ankyrin repeat domain 12 0.0729823
DLG1 discs, large homolog 1 (Drosophila) 0.0714028
ERO1A endoplasmic reticulum oxidoreductase 1 alpha 0.0704745
SBF2 SET binding factor 2 0.0703115
RBPJ recombination signal binding protein for immunoglobulin kappa J region 0.0696397
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive 0.0652576
DSCAM Down syndrome cell adhesion molecule 0.063614
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 0.0610938
CACNB4 calcium channel, voltage-dependent, beta 4 subunit 0.0586965
TMEM65 transmembrane protein 65 0.0569715
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I 0.05562
CENPF centromere protein F, 350/400kDa 0.0554675
KMT2E lysine (K)-specific methyltransferase 2E 0.0541742
NAMPT nicotinamide phosphoribosyltransferase 0.053591
RBMS3 RNA binding motif, single stranded interacting protein 3 0.0532528
TOP2A topoisomerase (DNA) II alpha 170kDa 0.0524291
GOLGA4 golgin A4 0.0522257
TXNIP thioredoxin interacting protein 0.0516524
HELZ helicase with zinc finger 0.0499733
FNDC3B fibronectin type III domain containing 3B 0.0492255
ECT2 epithelial cell transforming 2 0.0488343
EVI5 ecotropic viral integration site 5 0.0478058
XPO1 exportin 1 0.0474912
KDM4C lysine (K)-specific demethylase 4C 0.0470192
FAM13A family with sequence similarity 13, member A 0.0467886
PHIP pleckstrin homology domain interacting protein 0.046109
NAV2 neuron navigator 2 0.0450181
UBA6 ubiquitin-like modifier activating enzyme 6 0.0441671
UBR5 ubiquitin protein ligase E3 component n-recognin 5 0.0441596
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 0.043039
TJP1 tight junction protein 1 0.0427733
RPL3 ribosomal protein L3 0.041951
BIRC6 baculoviral IAP repeat containing 6 0.0419291
CAMTA1 calmodulin binding transcription activator 1 0.0409861
MINDY2 MINDY lysine 48 deubiquitinase 2 0.0407851
ADAM9 ADAM metallopeptidase domain 9 0.0407628
ZMYM2 zinc finger, MYM-type 2 0.0403021
GSK3B glycogen synthase kinase 3 beta 0.040286
NCKAP1 NCK-associated protein 1 0.0402815
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like 0.0402516
NBAS neuroblastoma amplified sequence 0.0401545
HIVEP2 human immunodeficiency virus type I enhancer binding protein 2 0.0396649
SLMAP sarcolemma associated protein 0.0395769
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 0.0394683
NUP58 nucleoporin 58 0.0392536
RALGAPA2 Ral GTPase activating protein, alpha subunit 2 (catalytic) 0.0392159
PNISR PNN-interacting serine/arginine-rich protein 0.0391216
BRWD1 bromodomain and WD repeat domain containing 1 0.0386998
ZCCHC7 zinc finger, CCHC domain containing 7 0.0384713
SMYD3 SET and MYND domain containing 3 0.0382383
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) 0.038007
RAB1A RAB1A, member RAS oncogene family 0.0379722
KIF13A kinesin family member 13A 0.0379395
B2M beta-2-microglobulin 0.0378324
MXI1 MAX interactor 1, dimerization protein 0.0375471
PGK1 phosphoglycerate kinase 1 0.0370173
CD47 CD47 molecule 0.0369048
TFG TRK-fused gene 0.0362202
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.0362111
FHIT fragile histidine triad 0.0360988
LPP LIM domain containing preferred translocation partner in lipoma 0.0359265
DENND4A DENN/MADD domain containing 4A 0.0356879
MBNL2 muscleblind-like splicing regulator 2 0.0352141
HDAC9 histone deacetylase 9 0.0348622
INSIG2 insulin induced gene 2 0.0347028
SRP54 signal recognition particle 54kDa 0.0345327
EFNA5 ephrin-A5 0.034506
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 0.0344819
TPD52 tumor protein D52 0.0343955
MAP3K2 mitogen-activated protein kinase kinase kinase 2 0.0343931
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 0.0343294
CNOT6L CCR4-NOT transcription complex, subunit 6-like 0.0342138
AKAP9 A kinase (PRKA) anchor protein 9 0.0340561
FNIP1 folliculin interacting protein 1 0.0329623
RPS8 ribosomal protein S8 0.0327673
MGAT5 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase 0.0327379
ARID4B AT rich interactive domain 4B (RBP1-like) 0.032563
FLNB filamin B, beta 0.032453
TNRC6B trinucleotide repeat containing 6B 0.0323615
SMC3 structural maintenance of chromosomes 3 0.0321043
YEATS2 YEATS domain containing 2 0.0318826
GNPDA1 glucosamine-6-phosphate deaminase 1 0.0317736
RPL4 ribosomal protein L4 0.0317297
CDC73 cell division cycle 73 0.0316924
PDS5B PDS5 cohesin associated factor B 0.031583
PCCA propionyl CoA carboxylase, alpha polypeptide 0.0313349
PPP2R2A protein phosphatase 2, regulatory subunit B, alpha 0.0312088
RAB6A RAB6A, member RAS oncogene family 0.0311744
HILPDA hypoxia inducible lipid droplet-associated 0.0308933
GLS2 glutaminase 2 (liver, mitochondrial) 0.0307965
RLF rearranged L-myc fusion 0.030195
RNF145 ring finger protein 145 0.0295683
COPA coatomer protein complex, subunit alpha 0.0295338
KDM3A lysine (K)-specific demethylase 3A 0.0294797

decreased expression

Symbol Name Standardized Value
EEF2 eukaryotic translation elongation factor 2 -0.116258
AHNAK AHNAK nucleoprotein -0.110286
LOC112694756 uncharaterized LOC112694756 -0.0914752
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) -0.0617787
CPED1 cadherin-like and PC-esterase domain containing 1 -0.058191
EGFR epidermal growth factor receptor -0.0542149
FOXP1 forkhead box P1 -0.0521533
CCND1 cyclin D1 -0.0485751
BMP10 bone morphogenetic protein 10 -0.0434491
HDLBP high density lipoprotein binding protein -0.0433169
SCD stearoyl-CoA desaturase (delta-9-desaturase) -0.0431968
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 -0.0420233
RPS6 ribosomal protein S6 -0.0399029
STAT1 signal transducer and activator of transcription 1, 91kDa -0.0394874
PARP14 poly (ADP-ribose) polymerase family, member 14 -0.0367552
TXNRD1 thioredoxin reductase 1 -0.0349975
IARS1 isoleucyl-tRNA synthetase 1 -0.0344984
EIF2S2 eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa -0.0329956
ENOX1 ecto-NOX disulfide-thiol exchanger 1 -0.0324025
RIGI RNA sensor RIG-I -0.0317287
GLI3 GLI family zinc finger 3 -0.0312888
SP100 SP100 nuclear antigen -0.0311656
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 -0.0310526
RPL35A ribosomal protein L35a -0.0306342
CYB5B cytochrome b5 type B (outer mitochondrial membrane) -0.0304796
MTHFD1L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like -0.0304067
ASNS asparagine synthetase (glutamine-hydrolyzing) -0.0300438
TAF1D TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa -0.0295024
TACC2 transforming, acidic coiled-coil containing protein 2 -0.0290063
PDE4D phosphodiesterase 4D, cAMP-specific -0.0280304
ZFAND3 zinc finger, AN1-type domain 3 -0.0275099
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) -0.0272067
GLI2 GLI family zinc finger 2 -0.0271272
PDE7B phosphodiesterase 7B -0.0266298
NT5C2 5'-nucleotidase, cytosolic II -0.0262748
CARS1 cysteinyl-tRNA synthetase 1 -0.0255638
DOCK3 dedicator of cytokinesis 3 -0.025351
NFE2L2 nuclear factor, erythroid 2-like 2 -0.0252653
TBL1X transducin (beta)-like 1X-linked -0.0243173
ANKRD11 ankyrin repeat domain 11 -0.0242349
FKBP10 FK506 binding protein 10, 65 kDa -0.0242075
FBLN2 fibulin 2 -0.0240965
HLA-B major histocompatibility complex, class I, B -0.024094
ZNFX1 zinc finger, NFX1-type containing 1 -0.0239649
WARS1 tryptophanyl-tRNA synthetase 1 -0.0232899
FER1L6 fer-1-like family member 6 -0.0232635
ARF1 ADP-ribosylation factor 1 -0.0223205
ALDH1A2 aldehyde dehydrogenase 1 family, member A2 -0.0222226
SPRY4 sprouty homolog 4 (Drosophila) -0.0218265
ARHGAP25 Rho GTPase activating protein 25 -0.0218106
ZC3HAV1 zinc finger CCCH-type, antiviral 1 -0.0217728
HLA-C major histocompatibility complex, class I, C -0.0215406
MLIP muscular LMNA-interacting protein -0.0211727
LARP1 La ribonucleoprotein domain family, member 1 -0.0211101
ZMYND8 zinc finger, MYND-type containing 8 -0.0210817
ANK2 ankyrin 2, neuronal -0.0206132
RRAS2 related RAS viral (r-ras) oncogene homolog 2 -0.020321
DHFR dihydrofolate reductase -0.0202967
GDI2 GDP dissociation inhibitor 2 -0.020118
MTAP methylthioadenosine phosphorylase -0.0199788
GALNT5 polypeptide N-acetylgalactosaminyltransferase 5 -0.0194938
PRDM16 PR domain containing 16 -0.0193505
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 -0.0192425
GANAB glucosidase, alpha; neutral AB -0.019237
KLF6 Kruppel-like factor 6 -0.0186943
EXT1 exostosin glycosyltransferase 1 -0.0183746
IFI16 interferon, gamma-inducible protein 16 -0.017952
YARS1 tyrosyl-tRNA synthetase 1 -0.0179217
TARS1 threonyl-tRNA synthetase 1 -0.017837
GCLM glutamate-cysteine ligase, modifier subunit -0.0177634
HLA-E major histocompatibility complex, class I, E -0.017683
MYC v-myc avian myelocytomatosis viral oncogene homolog -0.0173167
COMMD10 COMM domain containing 10 -0.0172782
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 -0.0171982
CRPPA CDP-L-ribitol pyrophosphorylase A -0.0171202
PARVA parvin, alpha -0.0170818
TEAD1 TEA domain family member 1 (SV40 transcriptional enhancer factor) -0.017069
BICD1 bicaudal D homolog 1 (Drosophila) -0.0169163
PWWP2A PWWP domain containing 2A -0.0168764
FHAD1 forkhead-associated (FHA) phosphopeptide binding domain 1 -0.0166905
PLSCR1 phospholipid scramblase 1 -0.0165922
FASN fatty acid synthase -0.0165638
EIF1 eukaryotic translation initiation factor 1 -0.0164226
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) -0.0163781
VTI1A vesicle transport through interaction with t-SNAREs 1A -0.0163437
ZNF438 zinc finger protein 438 -0.0161557
S100A6 S100 calcium binding protein A6 -0.0161405
UBR3 ubiquitin protein ligase E3 component n-recognin 3 (putative) -0.0160603
IRS1 insulin receptor substrate 1 -0.0160391
RHOB ras homolog family member B -0.0155354
GNL3L guanine nucleotide binding protein-like 3 (nucleolar)-like -0.0153899
CCT4 chaperonin containing TCP1, subunit 4 (delta) -0.0152861
CLIC4 chloride intracellular channel 4 -0.0152712
ENTPD6 ectonucleoside triphosphate diphosphohydrolase 6 (putative) -0.0152078
PLXNA1 plexin A1 -0.0151965
ONECUT2 one cut homeobox 2 -0.0151831
POTEF POTE ankyrin domain family, member F -0.0151786
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3 -0.0150548
PATJ PATJ crumbs cell polarity complex component -0.014944
NARS1 asparaginyl-tRNA synthetase 1 -0.0148636