| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ornidazole perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Ornidazole_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TRIO | trio Rho guanine nucleotide exchange factor | 0.210107 |
| FNDC3B | fibronectin type III domain containing 3B | 0.178464 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.16388 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.143525 |
| ZNF292 | zinc finger protein 292 | 0.13671 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.13116 |
| PDE10A | phosphodiesterase 10A | 0.107191 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.101379 |
| CADM1 | cell adhesion molecule 1 | 0.0931563 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0887395 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0862236 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0856127 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0781369 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0764997 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0751326 |
| NAV2 | neuron navigator 2 | 0.0724268 |
| FMNL2 | formin-like 2 | 0.0723304 |
| PGK1 | phosphoglycerate kinase 1 | 0.0714731 |
| PRELID2 | PRELI domain containing 2 | 0.0707489 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0691231 |
| NDRG1 | N-myc downstream regulated 1 | 0.0677818 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0670573 |
| GOLGA4 | golgin A4 | 0.0664194 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0650702 |
| HELZ | helicase with zinc finger | 0.0635755 |
| ATP13A3 | ATPase type 13A3 | 0.0607855 |
| OGA | O-GlcNAcase | 0.0593668 |
| FNIP1 | folliculin interacting protein 1 | 0.0586766 |
| RPS12 | ribosomal protein S12 | 0.0567711 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0565834 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0556874 |
| B2M | beta-2-microglobulin | 0.0531713 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.053067 |
| VEGFA | vascular endothelial growth factor A | 0.0510855 |
| PTMA | prothymosin, alpha | 0.0505969 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0501717 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0489102 |
| PHF21A | PHD finger protein 21A | 0.0480045 |
| FLNB | filamin B, beta | 0.047802 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.047401 |
| FLOT1 | flotillin 1 | 0.0472611 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0471891 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.046869 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0465085 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.04645 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0464213 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0459598 |
| JMJD1C | jumonji domain containing 1C | 0.0454874 |
| MYOF | myoferlin | 0.0439586 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0438813 |
| SETD5 | SET domain containing 5 | 0.043092 |
| FOXO3 | forkhead box O3 | 0.0427375 |
| GRIN2A | glutamate receptor, ionotropic, N-methyl D-aspartate 2A | 0.0421987 |
| NGLY1 | N-glycanase 1 | 0.0416695 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0416499 |
| DST | dystonin | 0.0414763 |
| CNNM2 | cyclin and CBS domain divalent metal cation transport mediator 2 | 0.0407424 |
| SNX9 | sorting nexin 9 | 0.0403939 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0403306 |
| FAM13A | family with sequence similarity 13, member A | 0.0401419 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 0.0400517 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0393837 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0387695 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0387618 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.03873 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0381481 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0376455 |
| STC1 | stanniocalcin 1 | 0.0374627 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.036824 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0365214 |
| YEATS2 | YEATS domain containing 2 | 0.0360098 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.035934 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0359169 |
| ARFGEF3 | ARFGEF family member 3 | 0.0355545 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0355139 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0355036 |
| NT5C2 | 5'-nucleotidase, cytosolic II | 0.0352708 |
| ARRDC3 | arrestin domain containing 3 | 0.0348165 |
| RPS8 | ribosomal protein S8 | 0.0345696 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0345215 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0342915 |
| RUNX1 | runt-related transcription factor 1 | 0.0342632 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0334133 |
| COPA | coatomer protein complex, subunit alpha | 0.0333023 |
| MMP12 | matrix metallopeptidase 12 | 0.0332371 |
| CDK19 | cyclin-dependent kinase 19 | 0.0331112 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0330948 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0329524 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0327075 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0326851 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0322898 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0321494 |
| WTAP | Wilms tumor 1 associated protein | 0.032107 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | 0.0319392 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0313118 |
| SPAG9 | sperm associated antigen 9 | 0.031264 |
| SBF2 | SET binding factor 2 | 0.0309942 |
| CENPF | centromere protein F, 350/400kDa | 0.030893 |
| USP37 | ubiquitin specific peptidase 37 | 0.03083 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0306533 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FTH1 | ferritin, heavy polypeptide 1 | -0.159415 |
| VCL | vinculin | -0.133817 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.133173 |
| FN1 | fibronectin 1 | -0.13076 |
| GLIS3 | GLIS family zinc finger 3 | -0.110034 |
| BICC1 | BicC family RNA binding protein 1 | -0.0832412 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0824091 |
| NABP1 | nucleic acid binding protein 1 | -0.067685 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0498911 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0485352 |
| EGR1 | early growth response 1 | -0.0477442 |
| AHNAK | AHNAK nucleoprotein | -0.0474095 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0464422 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0452873 |
| RIGI | RNA sensor RIG-I | -0.0439614 |
| HMGA2 | high mobility group AT-hook 2 | -0.0428415 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0416588 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0403425 |
| RNF213 | ring finger protein 213 | -0.0402919 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0397474 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0389767 |
| PALLD | palladin, cytoskeletal associated protein | -0.0369635 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0348465 |
| GPC6 | glypican 6 | -0.0342489 |
| THBS1 | thrombospondin 1 | -0.0331677 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.0326219 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0321126 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0299002 |
| HLA-C | major histocompatibility complex, class I, C | -0.0297295 |
| HLA-A | major histocompatibility complex, class I, A | -0.0291345 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | -0.0288461 |
| DCBLD1 | discoidin, CUB and LCCL domain containing 1 | -0.0278699 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0278026 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.027162 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0267693 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0262693 |
| THBS2 | thrombospondin 2 | -0.0259504 |
| FLNA | filamin A, alpha | -0.0256124 |
| CTSD | cathepsin D | -0.0255826 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0247684 |
| NTN4 | netrin 4 | -0.0246688 |
| TUT7 | terminal uridylyl transferase 7 | -0.0244523 |
| LOX | lysyl oxidase | -0.0241037 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | -0.0233866 |
| PMP22 | peripheral myelin protein 22 | -0.0231197 |
| HLA-E | major histocompatibility complex, class I, E | -0.0224336 |
| ACTG1 | actin gamma 1 | -0.0218953 |
| VMP1 | vacuole membrane protein 1 | -0.02163 |
| INTS6 | integrator complex subunit 6 | -0.0214901 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0214892 |
| EHBP1 | EH domain binding protein 1 | -0.0213302 |
| GOPC | golgi-associated PDZ and coiled-coil motif containing | -0.0211644 |
| OSMR | oncostatin M receptor | -0.0207399 |
| TNNC1 | troponin C type 1 (slow) | -0.0207021 |
| TRIM55 | tripartite motif containing 55 | -0.0206899 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0202776 |
| SH3RF2 | SH3 domain containing ring finger 2 | -0.0201643 |
| XAF1 | XIAP associated factor 1 | -0.0193368 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0192861 |
| BOD1L1 | biorientation of chromosomes in cell division 1-like 1 | -0.0191492 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0189553 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0189158 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | -0.0188509 |
| SMAD2 | SMAD family member 2 | -0.0186119 |
| COL1A2 | collagen, type I, alpha 2 | -0.0184581 |
| GLIPR1 | GLI pathogenesis-related 1 | -0.0183635 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0183417 |
| SVIL | supervillin | -0.0182213 |
| MX1 | MX dynamin-like GTPase 1 | -0.0182175 |
| COL5A1 | collagen, type V, alpha 1 | -0.0180565 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | -0.0180061 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0176358 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0176078 |
| FAM20C | family with sequence similarity 20, member C | -0.0173483 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0173395 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | -0.0170012 |
| CREB5 | cAMP responsive element binding protein 5 | -0.0169562 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.016824 |
| KYNU | kynureninase | -0.0167169 |
| EPAS1 | endothelial PAS domain protein 1 | -0.0166717 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | -0.0164882 |
| CDK17 | cyclin-dependent kinase 17 | -0.0164869 |
| REEP3 | receptor accessory protein 3 | -0.0162807 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | -0.0161939 |
| FILIP1L | filamin A interacting protein 1-like | -0.0158784 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0158364 |
| TENM2 | teneurin transmembrane protein 2 | -0.0157858 |
| GBP1 | guanylate binding protein 1, interferon-inducible | -0.0156818 |
| KLF12 | Kruppel-like factor 12 | -0.0154496 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0152665 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.015213 |
| ANXA2 | annexin A2 | -0.0151663 |
| PPP1R10 | protein phosphatase 1, regulatory subunit 10 | -0.0151299 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0150394 |
| GOLGA3 | golgin A3 | -0.0150143 |
| STK17A | serine/threonine kinase 17a | -0.0149891 |
| CAVIN1 | caveolae associated protein 1 | -0.0147614 |
| HELZ2 | helicase with zinc finger 2, transcriptional coactivator | -0.0147146 |
| RAB22A | RAB22A, member RAS oncogene family | -0.0147079 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0144145 |