| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ornidazole perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Ornidazole_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL6A3 | collagen, type VI, alpha 3 | 0.296635 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0865581 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0838582 |
| HDAC9 | histone deacetylase 9 | 0.0786177 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.0777775 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0773671 |
| FAM13A | family with sequence similarity 13, member A | 0.0733789 |
| CDH13 | cadherin 13 | 0.0716548 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0660804 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0648771 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0636879 |
| NAV2 | neuron navigator 2 | 0.0611489 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0607565 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0599989 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.058257 |
| MYOF | myoferlin | 0.0568824 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0548967 |
| RTN4 | reticulon 4 | 0.0512753 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0492927 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0489197 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0488315 |
| FN1 | fibronectin 1 | 0.0482945 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0462469 |
| CDC27 | cell division cycle 27 | 0.0449779 |
| MTPN | myotrophin | 0.0444356 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0443552 |
| TOP1 | topoisomerase (DNA) I | 0.0440033 |
| ANLN | anillin, actin binding protein | 0.0434678 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.042827 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.042815 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0427431 |
| DIAPH3 | diaphanous-related formin 3 | 0.0427021 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0425532 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0423201 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0415146 |
| UBC | ubiquitin C | 0.0408131 |
| COL5A2 | collagen, type V, alpha 2 | 0.0406099 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0401629 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0401468 |
| WWOX | WW domain containing oxidoreductase | 0.0401293 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0395676 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0394473 |
| WDFY2 | WD repeat and FYVE domain containing 2 | 0.0388936 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0386944 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0384957 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | 0.038314 |
| EGFR | epidermal growth factor receptor | 0.0380857 |
| RPL3 | ribosomal protein L3 | 0.0380621 |
| RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 | 0.0369907 |
| ASPH | aspartate beta-hydroxylase | 0.0369904 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0367442 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.036445 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0363833 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0363352 |
| ANTXR2 | anthrax toxin receptor 2 | 0.0363141 |
| ZNF638 | zinc finger protein 638 | 0.0363122 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0362918 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0362003 |
| MT2A | metallothionein 2A | 0.0361078 |
| MKI67 | marker of proliferation Ki-67 | 0.0358223 |
| DOCK1 | dedicator of cytokinesis 1 | 0.0356765 |
| NRXN3 | neurexin 3 | 0.0356143 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0346812 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0346507 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0345736 |
| QKI | QKI, KH domain containing, RNA binding | 0.034543 |
| USP37 | ubiquitin specific peptidase 37 | 0.0344805 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0344178 |
| SLC39A8 | solute carrier family 39 (zinc transporter), member 8 | 0.0343561 |
| TPM1 | tropomyosin 1 (alpha) | 0.0339755 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0339695 |
| CBX3 | chromobox homolog 3 | 0.0339598 |
| COL8A1 | collagen, type VIII, alpha 1 | 0.0335735 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | 0.0332764 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0331886 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.0331202 |
| XPO1 | exportin 1 | 0.032393 |
| TENT2 | terminal nucleotidyltransferase 2 | 0.0322404 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0317802 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | 0.0314825 |
| ANXA2 | annexin A2 | 0.0314697 |
| SYNPO | synaptopodin | 0.0314325 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0310719 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0310481 |
| RRM2 | ribonucleotide reductase M2 | 0.0303505 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0299696 |
| NCOR1 | nuclear receptor corepressor 1 | 0.0295429 |
| STARD13 | StAR-related lipid transfer (START) domain containing 13 | 0.0292916 |
| RPL30 | ribosomal protein L30 | 0.0292728 |
| IGFBP7 | insulin-like growth factor binding protein 7 | 0.0291471 |
| SNX25 | sorting nexin 25 | 0.0291018 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0290114 |
| AFF3 | AF4/FMR2 family, member 3 | 0.0289802 |
| KYNU | kynureninase | 0.0283895 |
| TNRC6A | trinucleotide repeat containing 6A | 0.02837 |
| SBF2 | SET binding factor 2 | 0.0283539 |
| ZNF148 | zinc finger protein 148 | 0.0282774 |
| CPAP | centrosome assembly and centriole elongation protein | 0.0282702 |
| INSIG2 | insulin induced gene 2 | 0.0280802 |
| LAMB1 | laminin, beta 1 | 0.0279059 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.161522 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.105113 |
| HLA-B | major histocompatibility complex, class I, B | -0.0982354 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0968315 |
| FTL | ferritin, light polypeptide | -0.0899071 |
| SDC4 | syndecan 4 | -0.0819092 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0741129 |
| TMSB10 | thymosin beta 10 | -0.0679042 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0658563 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0615502 |
| COL1A2 | collagen, type I, alpha 2 | -0.0614744 |
| SLC16A1 | solute carrier family 16 (monocarboxylate transporter), member 1 | -0.0584632 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0578324 |
| LOX | lysyl oxidase | -0.0570222 |
| ATP13A3 | ATPase type 13A3 | -0.056984 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0555493 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0543175 |
| CANX | calnexin | -0.0526851 |
| VCL | vinculin | -0.0515246 |
| IL6 | interleukin 6 | -0.0508558 |
| RPL34 | ribosomal protein L34 | -0.0478749 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0467479 |
| RPS12 | ribosomal protein S12 | -0.0461675 |
| NDFIP1 | Nedd4 family interacting protein 1 | -0.0447418 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.0437324 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0424293 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.0418878 |
| IFRD1 | interferon-related developmental regulator 1 | -0.0411593 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0404639 |
| FBXO11 | F-box protein 11 | -0.0402122 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0397231 |
| NF1 | neurofibromin 1 | -0.0386684 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0383944 |
| PDIA5 | protein disulfide isomerase family A, member 5 | -0.0368708 |
| EPAS1 | endothelial PAS domain protein 1 | -0.0368428 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0355205 |
| RYBP | RING1 and YY1 binding protein | -0.0352943 |
| BLTP1 | bridge-like lipid transfer protein family member 1 | -0.0350376 |
| MAPK8 | mitogen-activated protein kinase 8 | -0.0348344 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0347531 |
| LCOR | ligand dependent nuclear receptor corepressor | -0.034598 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0344811 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0344742 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0344124 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.034396 |
| EIF4H | eukaryotic translation initiation factor 4H | -0.0343405 |
| CEP350 | centrosomal protein 350kDa | -0.0342601 |
| AUTS2 | autism susceptibility candidate 2 | -0.034253 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | -0.0342346 |
| HM13 | histocompatibility (minor) 13 | -0.0342084 |
| ZFC3H1 | zinc finger, C3H1-type containing | -0.0340476 |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 | -0.0340189 |
| GNAI2 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 | -0.0338287 |
| SRSF11 | serine/arginine-rich splicing factor 11 | -0.0337202 |
| HLA-C | major histocompatibility complex, class I, C | -0.0331062 |
| NOP58 | NOP58 ribonucleoprotein | -0.0331033 |
| FRMD4A | FERM domain containing 4A | -0.0327621 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0324744 |
| NOTCH2 | notch 2 | -0.0322921 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.031693 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0315807 |
| OSMR | oncostatin M receptor | -0.0313386 |
| PRELID2 | PRELI domain containing 2 | -0.0309986 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0306563 |
| POTEF | POTE ankyrin domain family, member F | -0.0305803 |
| HLA-A | major histocompatibility complex, class I, A | -0.0304896 |
| FOXP1 | forkhead box P1 | -0.0303324 |
| CUL3 | cullin 3 | -0.0302772 |
| KLC1 | kinesin light chain 1 | -0.03014 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0297873 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0297695 |
| TPM4 | tropomyosin 4 | -0.0294595 |
| CPNE8 | copine VIII | -0.0293056 |
| EGR1 | early growth response 1 | -0.0290541 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0289935 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0285479 |
| PRPF3 | pre-mRNA processing factor 3 | -0.0284183 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.0281846 |
| PALLD | palladin, cytoskeletal associated protein | -0.0281092 |
| GORASP2 | golgi reassembly stacking protein 2, 55kDa | -0.0280664 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0279563 |
| UBAP1 | ubiquitin associated protein 1 | -0.027779 |
| TPST1 | tyrosylprotein sulfotransferase 1 | -0.0277393 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | -0.0276403 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0275835 |
| LDHA | lactate dehydrogenase A | -0.0275457 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | -0.0274896 |
| VASP | vasodilator-stimulated phosphoprotein | -0.0273138 |
| MYO1E | myosin IE | -0.0271711 |
| GNAS | GNAS complex locus | -0.0271414 |
| CALR | calreticulin | -0.027033 |
| SEC23IP | SEC23 interacting protein | -0.0268891 |
| CTNNBL1 | catenin, beta like 1 | -0.0268707 |
| DIP2A | DIP2 disco-interacting protein 2 homolog A (Drosophila) | -0.0268414 |
| RPL35A | ribosomal protein L35a | -0.0267388 |
| CALU | calumenin | -0.0266098 |
| RPL7A | ribosomal protein L7a | -0.0266082 |
| RNF216 | ring finger protein 216 | -0.0263743 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0263563 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0262533 |