Ornidazole_SW 1271 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Ornidazole perturbation in SW 1271 cell line (Tahoe Therapeutics)
Similar Terms
Downloads & Tools

Genes

200 genes differentially expressed following the Ornidazole_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
HILPDA hypoxia inducible lipid droplet-associated 0.119985
FMNL2 formin-like 2 0.0884365
FNDC3B fibronectin type III domain containing 3B 0.0878832
SMAD3 SMAD family member 3 0.0704879
PPFIBP1 PTPRF interacting protein, binding protein 1 (liprin beta 1) 0.0623364
RAD51B RAD51 paralog B 0.0617954
SMYD3 SET and MYND domain containing 3 0.0615399
ANKRD11 ankyrin repeat domain 11 0.0612516
WAC WW domain containing adaptor with coiled-coil 0.0597429
ERBIN erbb2 interacting protein 0.05875
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) 0.0579473
KIAA1328 KIAA1328 0.0564099
ZC3HAV1 zinc finger CCCH-type, antiviral 1 0.0553768
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) 0.0543805
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 0.0539272
ERO1A endoplasmic reticulum oxidoreductase 1 alpha 0.0533875
ATXN1 ataxin 1 0.053083
MACF1 microtubule-actin crosslinking factor 1 0.050598
UBR5 ubiquitin protein ligase E3 component n-recognin 5 0.0496373
SOD2 superoxide dismutase 2, mitochondrial 0.0483663
YAP1 Yes-associated protein 1 0.0480238
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 0.047923
UACA uveal autoantigen with coiled-coil domains and ankyrin repeats 0.0469608
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I 0.0464067
ZFAND3 zinc finger, AN1-type domain 3 0.0462033
APP amyloid beta (A4) precursor protein 0.0460127
PTK2 protein tyrosine kinase 2 0.0452557
PALM2AKAP2 PALM2 and AKAP2 fusion 0.0445119
RAB1A RAB1A, member RAS oncogene family 0.0442446
LRRFIP2 leucine rich repeat (in FLII) interacting protein 2 0.0437891
COG5 component of oligomeric golgi complex 5 0.0432548
NAV2 neuron navigator 2 0.0427869
SLC35F2 solute carrier family 35, member F2 0.0425446
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase 0.0424933
PARD3 par-3 family cell polarity regulator 0.0415046
SNX14 sorting nexin 14 0.0412859
SET SET nuclear proto-oncogene 0.0409849
SETD5 SET domain containing 5 0.0408963
RBM39 RNA binding motif protein 39 0.0405251
DERA deoxyribose-phosphate aldolase (putative) 0.0403146
UBE2E2 ubiquitin-conjugating enzyme E2E 2 0.0402399
ESYT2 extended synaptotagmin-like protein 2 0.0398026
PHLDB2 pleckstrin homology-like domain, family B, member 2 0.0397599
PHF21A PHD finger protein 21A 0.0388399
KCMF1 potassium channel modulatory factor 1 0.0385272
PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1 0.0382827
VMP1 vacuole membrane protein 1 0.0380782
JMJD1C jumonji domain containing 1C 0.0380137
PHF20 PHD finger protein 20 0.0375583
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2 0.0366272
AKAP12 A kinase (PRKA) anchor protein 12 0.0364339
NAMPT nicotinamide phosphoribosyltransferase 0.0364074
NKTR natural killer cell triggering receptor 0.0363191
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1 0.0362998
RAB10 RAB10, member RAS oncogene family 0.036023
CRY1 cryptochrome circadian clock 1 0.0359875
NUP58 nucleoporin 58 0.0356592
ADAM10 ADAM metallopeptidase domain 10 0.0355979
USP37 ubiquitin specific peptidase 37 0.035337
OSBPL8 oxysterol binding protein-like 8 0.0352963
RASA2 RAS p21 protein activator 2 0.035096
NUMA1 nuclear mitotic apparatus protein 1 0.0348192
AKT3 v-akt murine thymoma viral oncogene homolog 3 0.0346347
NAP1L1 nucleosome assembly protein 1-like 1 0.0346186
DLGAP4 discs, large (Drosophila) homolog-associated protein 4 0.0343043
ANKRD17 ankyrin repeat domain 17 0.0343005
ANKRD36C ankyrin repeat domain 36C 0.0342889
MAPK8 mitogen-activated protein kinase 8 0.0342295
HIVEP2 human immunodeficiency virus type I enhancer binding protein 2 0.0341099
COA1 cytochrome c oxidase assembly factor 1 homolog (S. cerevisiae) 0.0338137
SLMAP sarcolemma associated protein 0.0338038
FUS FUS RNA binding protein 0.0337734
SBF2 SET binding factor 2 0.033699
PPP6R3 protein phosphatase 6, regulatory subunit 3 0.0335418
UBE2K ubiquitin-conjugating enzyme E2K 0.0332671
TXNIP thioredoxin interacting protein 0.0331108
SEC24A SEC24 family member A 0.0331096
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1 0.032949
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 0.032639
UBR4 ubiquitin protein ligase E3 component n-recognin 4 0.0324167
KDM6A lysine (K)-specific demethylase 6A 0.0323924
SMC6 structural maintenance of chromosomes 6 0.0318018
TRA2A transformer 2 alpha homolog (Drosophila) 0.0312666
CTNND1 catenin (cadherin-associated protein), delta 1 0.031053
CUL4B cullin 4B 0.0310329
ANKIB1 ankyrin repeat and IBR domain containing 1 0.030915
BAIAP2L1 BAI1-associated protein 2-like 1 0.0307359
MYH9 myosin, heavy chain 9, non-muscle 0.0307293
SOS2 son of sevenless homolog 2 (Drosophila) 0.0304867
TMCC1 transmembrane and coiled-coil domain family 1 0.0304556
C2ORF42 chromosome 2 open reading frame 42 0.0304345
ZFAND6 zinc finger, AN1-type domain 6 0.0303767
YY1 YY1 transcription factor 0.0301243
RIN2 Ras and Rab interactor 2 0.0299352
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase 0.0298596
ELF2 E74-like factor 2 (ets domain transcription factor) 0.0297428
RICTOR RPTOR independent companion of MTOR, complex 2 0.0296573
FLNB filamin B, beta 0.0296388
ARID2 AT rich interactive domain 2 (ARID, RFX-like) 0.0295364
ZMYM2 zinc finger, MYM-type 2 0.0294134

decreased expression

Symbol Name Standardized Value
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.125699
FTH1 ferritin, heavy polypeptide 1 -0.112202
LOC112694756 uncharaterized LOC112694756 -0.0924895
EEF2 eukaryotic translation elongation factor 2 -0.0650434
VIM vimentin -0.0584058
TAS2R14 taste receptor, type 2, member 14 -0.0577601
SPTAN1 spectrin, alpha, non-erythrocytic 1 -0.0549557
ZNF638 zinc finger protein 638 -0.0515791
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa -0.046768
MAP1B microtubule-associated protein 1B -0.0461992
BDP1 B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB -0.04618
RPL19 ribosomal protein L19 -0.0441547
PKM pyruvate kinase, muscle -0.0415538
CAMKMT calmodulin-lysine N-methyltransferase -0.0413191
RPL35A ribosomal protein L35a -0.0412945
EPN2 epsin 2 -0.0407009
BSG basigin (Ok blood group) -0.0399774
RPL11 ribosomal protein L11 -0.039916
EIF2S2 eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa -0.0393434
PTGES3 prostaglandin E synthase 3 (cytosolic) -0.0379281
RPLP1 ribosomal protein, large, P1 -0.0377883
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila) -0.0370167
P4HB prolyl 4-hydroxylase, beta polypeptide -0.0368909
PHF3 PHD finger protein 3 -0.0363663
DENND4A DENN/MADD domain containing 4A -0.035658
BIRC6 baculoviral IAP repeat containing 6 -0.0356544
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 -0.0354835
AFF4 AF4/FMR2 family, member 4 -0.0349241
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 -0.0342688
TPI1 triosephosphate isomerase 1 -0.0339999
HLA-C major histocompatibility complex, class I, C -0.0338885
FSCN1 fascin actin-bundling protein 1 -0.0337873
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase -0.0337161
CALM2 calmodulin 2 (phosphorylase kinase, delta) -0.0335301
BICD1 bicaudal D homolog 1 (Drosophila) -0.0327975
IARS1 isoleucyl-tRNA synthetase 1 -0.0323936
NCOA1 nuclear receptor coactivator 1 -0.0311807
HM13 histocompatibility (minor) 13 -0.0311273
TUBA1B tubulin, alpha 1b -0.0310369
CUL5 cullin 5 -0.0309018
RALY RALY heterogeneous nuclear ribonucleoprotein -0.0308812
IGFBP3 insulin-like growth factor binding protein 3 -0.0307483
GPATCH2L G patch domain containing 2-like -0.0306606
RPS14 ribosomal protein S14 -0.0299963
MED13L mediator complex subunit 13-like -0.0299167
LGALS1 lectin, galactoside-binding, soluble, 1 -0.0298675
ARL15 ADP-ribosylation factor-like 15 -0.029721
ARIH1 ariadne RBR E3 ubiquitin protein ligase 1 -0.029706
ZBTB10 zinc finger and BTB domain containing 10 -0.0295698
HMGA1 high mobility group AT-hook 1 -0.0294511
EEF1G eukaryotic translation elongation factor 1 gamma -0.0293865
GNAS GNAS complex locus -0.0291441
TUT4 terminal uridylyl transferase 4 -0.0289323
BRD2 bromodomain containing 2 -0.0289262
ADIPOR2 adiponectin receptor 2 -0.0289242
WNK1 WNK lysine deficient protein kinase 1 -0.0285386
AP2B1 adaptor-related protein complex 2, beta 1 subunit -0.0284473
ZFAND5 zinc finger, AN1-type domain 5 -0.0283702
SRSF10 serine/arginine-rich splicing factor 10 -0.0282496
ATXN7 ataxin 7 -0.0281565
GFPT1 glutamine--fructose-6-phosphate transaminase 1 -0.0281543
GOLGA2 golgin A2 -0.0280051
PTMS parathymosin -0.0279457
PABPC1 poly(A) binding protein, cytoplasmic 1 -0.0278103
ARF4 ADP-ribosylation factor 4 -0.0276803
MTDH metadherin -0.0275162
EHBP1 EH domain binding protein 1 -0.0273915
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1 -0.0272746
LARS1 leucyl-tRNA synthetase 1 -0.0272708
UBB ubiquitin B -0.0272515
NEK6 NIMA-related kinase 6 -0.0272027
SEMA4B sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B -0.0271966
RDX radixin -0.0268598
LIMCH1 LIM and calponin homology domains 1 -0.0267987
MLEC malectin -0.0267078
LRBA LPS-responsive vesicle trafficking, beach and anchor containing -0.0265543
SCD stearoyl-CoA desaturase (delta-9-desaturase) -0.0265466
SCFD1 sec1 family domain containing 1 -0.0264955
GLCCI1 glucocorticoid induced 1 -0.0264721
CENPF centromere protein F, 350/400kDa -0.0263883
NT5C2 5'-nucleotidase, cytosolic II -0.0262954
PNPLA8 patatin-like phospholipase domain containing 8 -0.0259301
RPL7 ribosomal protein L7 -0.0258908
MED17 mediator complex subunit 17 -0.0258242
RHOBTB3 Rho-related BTB domain containing 3 -0.0258155
RPL34 ribosomal protein L34 -0.0257592
PMEPA1 prostate transmembrane protein, androgen induced 1 -0.0257556
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase -0.025731
RB1 retinoblastoma 1 -0.0256213
AKAP9 A kinase (PRKA) anchor protein 9 -0.0250154
RPL35 ribosomal protein L35 -0.0248913
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1 -0.0248685
ALCAM activated leukocyte cell adhesion molecule -0.0247842
RABGAP1 RAB GTPase activating protein 1 -0.0247623
CLINT1 clathrin interactor 1 -0.0247557
ADGRG6 adhesion G protein-coupled receptor G6 -0.0246116
IKBIP IKBKB interacting protein -0.0245999
PIBF1 progesterone immunomodulatory binding factor 1 -0.0245691
ANLN anillin, actin binding protein -0.0245342
MECP2 methyl CpG binding protein 2 -0.0245138